Journal of Biomedical Optics
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Monte Carlo simulation of optical coherence tomography for turbid media with arbitrary spatial distributions.
We developed a Monte Carlo-based simulator of optical coherence tomography (OCT) imaging for turbid media with arbitrary spatial distributions. This simulator allows computation of both Class I diffusive reflectance due to ballistic and quasiballistic scattered photons and Class II diffusive reflect...
Diffuser-aided time-domain diffuse optical imaging: a phantom study.
We present the first experimental results of time-resolved diffuser-aided diffuse optical imaging (DADOI) method in this paper. A self-manufactured diffuser plate was inserted between the optode and the surface of a scattering medium. The diffuser was utilized to enhance the multiple scattering that...
Artery phantoms for intravascular optical coherence tomography: diseased arteries.
We propose and test various strategies for the creation of artery phantoms mimicking different kinds of diseased arteries when imaged by intravascular optical coherence tomography (IVOCT). We first review the method for making healthy artery phantoms. We then describe the procedure to fabricate dise...
Spatiotemporal analysis for indocyanine green-aided imaging of rheumatoid arthritis in hand joints.
Rheumatoid arthritis (RA) is the most common chronic inflammatory joint disease, with a prevalence of 0.5 to 1% in the general population. Imaging can possibly aid in early diagnosis, crucial to effective personalized therapeutic strategies and treatment follow-up. The intravenous administration of...
Femtosecond laser etching of dental enamel for bracket bonding.
The aim is to investigate femtosecond laser ablation as an alternative method for enamel etching used before bonding orthodontic brackets. A focused laser beam is scanned over enamel within the area of bonding in a saw tooth pattern with a varying number of lines. After patterning, ceramic brackets...
Elucidation of the mechanisms of optical clearing in collagen tissue with multiphoton imaging.
We also found that phosphate-buffered saline- and glycerol-treatments were reversible, and fiber morphology and SHG signal intensity were recovered after the removal of immersion agents. It was shown that tissue OC was a dynamic process and elucidation of its physical mechanisms may help choose opti...
Comprehensive data visualization for high resolution endovascular carotid arterial wall imaging.
Carotid angioplasty and stenting is a minimally invasive endovascular procedure that may benefit from in vivo high resolution imaging for monitoring the physical placement of the stent and potential complications. The purpose of this pilot study was to evaluate the ability of optical...
Errata: Localization capability and limitation of electron-multiplying charge-coupled, scientific complementary metal-oxide semiconductor, a...
Second harmonic generation signal in collagen fibers: role of polarization, numerical aperture, and wavelength.
Our results show that polarization modulates the SHG signal. Elliptical polarization can generate high signals (even greater than those corresponding to linear polarization) when combined with appropriate values of both incident wavelength and NA. On the other hand, the SHG intensity might also be i...
Optodynamic monitoring of laser tattoo removal.
We simultaneously employed a laser-beam deflection probe (LBDP) to measure the shock wave and a camera to detect the plasma radiation, both originating from a high-intensity laser-pulse interaction with a tattoo. The experiments were performed in vitro (skin phantoms), ex vivo (marking tattoos on pi...