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Journal of Biomedical Optics

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  1. Artery phantoms for intravascular optical coherence tomography: diseased arteries.

    Journal of Biomedical Optics 18(9):096010 (2013) PMID 24022516

    We propose and test various strategies for the creation of artery phantoms mimicking different kinds of diseased arteries when imaged by intravascular optical coherence tomography (IVOCT). We first review the method for making healthy artery phantoms. We then describe the procedure to fabricate dise...
  2. Spatiotemporal analysis for indocyanine green-aided imaging of rheumatoid arthritis in hand joints.

    Journal of Biomedical Optics 18(9):097004 (2013) PMID 24045692

    Rheumatoid arthritis (RA) is the most common chronic inflammatory joint disease, with a prevalence of 0.5 to 1% in the general population. Imaging can possibly aid in early diagnosis, crucial to effective personalized therapeutic strategies and treatment follow-up. The intravenous administration of...
  3. Femtosecond laser etching of dental enamel for bracket bonding.

    Journal of Biomedical Optics 18(9):098003 (2013) PMID 24045693

    The aim is to investigate femtosecond laser ablation as an alternative method for enamel etching used before bonding orthodontic brackets. A focused laser beam is scanned over enamel within the area of bonding in a saw tooth pattern with a varying number of lines. After patterning, ceramic brackets...
  4. Elucidation of the mechanisms of optical clearing in collagen tissue with multiphoton imaging.

    Journal of Biomedical Optics 18(4):40104 (2013) PMID 23549411

    We also found that phosphate-buffered saline- and glycerol-treatments were reversible, and fiber morphology and SHG signal intensity were recovered after the removal of immersion agents. It was shown that tissue OC was a dynamic process and elucidation of its physical mechanisms may help choose opti...
  5. Comprehensive data visualization for high resolution endovascular carotid arterial wall imaging.

    Journal of Biomedical Optics 17(5):056003 (2012) PMID 22612126

    Carotid angioplasty and stenting is a minimally invasive endovascular procedure that may benefit from in vivo high resolution imaging for monitoring the physical placement of the stent and potential complications. The purpose of this pilot study was to evaluate the ability of optical...
  6. Errata: Localization capability and limitation of electron-multiplying charge-coupled, scientific complementary metal-oxide semiconductor, a...

    Journal of Biomedical Optics 17(4):049801 (2012) PMID 22559699

  7. Second harmonic generation signal in collagen fibers: role of polarization, numerical aperture, and wavelength.

    Journal of Biomedical Optics 17(4):045005 (2012) PMID 22559679

    Our results show that polarization modulates the SHG signal. Elliptical polarization can generate high signals (even greater than those corresponding to linear polarization) when combined with appropriate values of both incident wavelength and NA. On the other hand, the SHG intensity might also be i...
  8. Optodynamic monitoring of laser tattoo removal.

    Journal of Biomedical Optics 17(4):047003 (2012) PMID 22559694

    We simultaneously employed a laser-beam deflection probe (LBDP) to measure the shock wave and a camera to detect the plasma radiation, both originating from a high-intensity laser-pulse interaction with a tattoo. The experiments were performed in vitro (skin phantoms), ex vivo (marking tattoos on pi...
  9. JBO Setting New Records.

    Journal of Biomedical Optics 17(2):020101 (2012) PMID 22463017

  10. Single myelin fiber imaging in living rodents without labeling by deep optical coherence microscopy.

    Journal of Biomedical Optics 16(11):116012 (2011) PMID 22112117

    We perform myelin imaging without labeling and at micron-scale resolution with >300-μm penetration depth on living rodents. This was achieved with a prototype [termed deep optical coherence microscopy (deep-OCM)] of a high-numerical aperture infrared full-field optical coherence microscope, which i...