Microbiology and Molecular Biology Reviews
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- Aaas, Csh, American Society for Microbiology (ASM), Gale, Proquest, Rupress, Endocrine, Aacr, Ama, ASM, Nephrology, CSA, and Highwire from 1937
Higher levels of organization in the interphase nucleus of cycling and differentiated cells.
The review examines the structured organization of interphase nuclei using a range of examples from the plants, animals, and fungi. Nuclear organization is shown to be an important phenomenon in cell differentiation and development. The review commences by examining nuclei in dividing cells and show...
Membrane topology and insertion of membrane proteins: search for topogenic signals.
Integral membrane proteins are found in all cellular membranes and carry out many of the functions that are essential to life. The membrane-embedded domains of integral membrane proteins are structurally quite simple, allowing the use of various prediction methods and biochemical methods to obtain s...
Mechanisms of Giardia lamblia differentiation into cysts.
We summarize the most recent fundings on several aspects of Giardia differentiation and discuss the significance of these findings within the context of current knowledge in the field....
Biochemistry and evolution of anaerobic energy metabolism in eukaryotes.
We review the available biochemical data on the enzymes and pathways that eukaryotes use in anaerobic energy metabolism and summarize the metabolic end products that they generate in their anaerobic habitats, focusing on the biochemical roles that their mitochondria play in anaerobic ATP synthesis....
Genomics of bacterial and archaeal viruses: dynamics within the prokaryotic virosphere.
We discuss all families of bacterial and archaeal viruses that contain more than one characterized member and for which evolutionary conclusions can be attempted by use of comparative genomic analysis. We focus on the molecular mechanisms of their genome evolution as well as on the relationships bet...
Gliding motility revisited: how do the myxobacteria move without flagella?
These results are summarized in this review....
Poxvirus proteomics and virus-host protein interactions.
We discuss poxvirus proteomics, including the use of proteomic methodologies to identify viral components and virus-host protein interactions. High-throughput global protein expression studies using protein chip technology as well as new methods for validating putative protein-protein interactions a...
Getting a handle on the role of coenzyme M in alkene metabolism.
Coenzyme M (2-mercaptoethanesulfonate; CoM) is one of several atypical cofactors discovered in methanogenic archaea which participate in the biological reduction of CO(2) to methane. Elegantly simple, CoM, so named for its role as a methyl carrier in all methanogenic archaea, is the smallest known o...
Molecular control of bacterial death and lysis.
Although the phenomenon of bacterial cell death and lysis has been studied for over 100 years, the contribution of these important processes to bacterial physiology and development has only recently been recognized. Contemporary study of cell death and lysis in a number of different bacteria has rev...
Impact of protein kinase PKR in cell biology: from antiviral to antiproliferative action.
We provide a detailed picture on how signaling downstream of PKR unfolds and what are the ultimate consequences for the cell fate. PKR activation affects both transcription and translation. PKR phosphorylation of the alpha subunit of eukaryotic initiation factor 2 results in a blockade on translatio...