Current Opinion in Clinical Nutrition and Metabolic Care
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Perioperative immunonutrition and gut function.
These results have been found in both upper and lower GI patients, regardless of their baseline nutritional status. Promising results have been found also in head and neck surgery. In the light of these findings the use of perioperative immunonutrition should be implemented in patien...
Segmental bioelectrical impedance analysis: an update.
Segmental impedance analysis tends to underestimate fat-free mass and overestimate fat mass when compared to reference techniques, although the magnitude of these differences can be small. Performance is improved with population-specific prediction equations; algorithms in-built into instrument firm...
Epigenetic regulation of adipogenesis.
The advent of high-throughput technologies has made possible the exhaustive analysis of the epigenetic phenomenons taking place during adipogenesis. The cooperative recruitment of CCAAT/enhancer-binding protein (C/EBPβ) and other early proadipogenic transcription factors to transcription factor hot...
Nonalcoholic fatty liver disease in children.
Pediatric NAFLD is an underdiagnosed condition which can result in significant liver injury including cirrhosis. Although liver biopsy remains the standard for diagnosis and monitoring disease activity, several noninvasive biomarkers and imaging techniques hold significant promise. Dietary constitue...
Role of zinc in the development and treatment of mood disorders.
The present review is a critical examination of the most recent published work on the role of zinc in the development and treatment of mood disorders. Clinical studies and experimental work using animal models have both revealed a link between zinc status and neuropsychological disorders such as dep...
Calories and cachexia.
Caloric supplementation improves outcomes in malnourished hospital patients and malnourished older persons. It may improve the quality of life in cancer patients and for those persons receiving palliative care. Caloric supplementation should include a balanced essential amino acid supplement given a...
Catabolism of lipoproteins and metabolic syndrome.
Dyslipidemia plays an important role in the development of atherosclerosis and is mainly associated by the hepatic overproduction of large triglyceride-rich VLDL, low levels of HDL cholesterol and high levels of small, dense, LDL cholesterol particles. It is thus of special interest to understand th...
Selenium supplementation in the critically ill: posology and pharmacokinetics.
Antioxidants and especially high-dose parenteral selenium may be associated with a significant reduction in mortality among critically ill patients with systemic inflammatory response syndrome (SIRS). Selenium seems to be a cornerstone of the antioxidant defense in SIRS patients. In the past few yea...
The risks of free copper in the body and the development of useful anticopper drugs.
Some exciting recent work indicates that free copper levels are increased in Alzheimer's disease, and copper may be involved in disease pathogenesis, opening the way to possible therapy of Alzheimer's disease with anticopper drugs. Copper may also be involved in other diseases of neurodegeneration....