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Pharmaceutical Biology

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  1. Evaluation of antidiabetic properties of cactus pear seed oil in rats.

    Pharmaceutical Biology 52(10):1286 (2014) PMID 25026333

    Cactus pear (Opuntia ficus-indica (L.) Mill. (Cactaceae)) is a medicinal plant widely used to treat diabetes. This work investigates the hypoglycemic and antihyperglycemic effect of cactus pear seed oil (CPSO), its mechanism of action, and any toxic effects. The hypoglycemic effect of CPSO was evalu...
  2. α-Glucosidase inhibition, 15-lipoxygenase inhibition, and brine shrimp toxicity of extracts and isolated compounds from Terminalia macropter...

    Pharmaceutical Biology 52(9):1166 (2014) PMID 24635511

    Terminalia macroptera Guill. & Perr. (Combretaceae), a tree that grows in West Africa, has been used in traditional medicine against a variety of diseases such as hepatitis, gonorrhea, skin diseases, and diabetes. To investigate enzyme inhibitory activity against α-glucosidase and 15-lipoxygenase (1...
  3. Ardisiphenol D, a resorcinol derivative identified from Ardisia brevicaulis, exerts antitumor effect through inducing apoptosis in human non...

    Pharmaceutical Biology 52(7):797 (2014) PMID 24392814

    We have isolated and identified some chemical constituents from this plant. Furthermore, these compounds showed significant inhibition of the proliferation of human pancreatic PANC-1, human lung A549, human gastrointestinal carcinoma SGC 7901, human breast MCF-7, and human prostate PC-3 cancer cells...
  4. Corrigendum.
    Author(s) unavailable

    Pharmaceutical Biology 52(7):933 (2014) PMID 24920236

  5. Nature cures nature: Hypericum perforatum attenuates physical withdrawal signs in opium dependent rats.

    Pharmaceutical Biology 52(5):586 (2014) PMID 24256159

    Hypericum perforatum Linn. (Hypericaceae) (St. John's wort) attenuates opium withdrawal signs. To explore the therapeutic potential of Hypericum perforatum in the management of opium-induced withdrawal syndrome. The effect of the Hypericum perforatum hydro-ethanol extract was investigated for potent...
  6. An LC-MS/MS method for the determination of salidroside and its metabolite p-tyrosol in rat liver tissues.

    Pharmaceutical Biology 52(5):637 (2014) PMID 24479765

    Salidroside and its metabolite p-tyrosol are two major phenols in the genus Rhodiola L. (Crassulaceae). They have been confirmed to possess various pharmacological properties and are used for the prophylaxis and therapeutics of many diseases. Several analytical methods have been developed for the de...
  7. HPLC fingerprint analysis combined with chemometrics for pattern recognition of ginger.

    Pharmaceutical Biology 52(3):362 (2014) PMID 24171804

    Ginger, the fresh rhizome of Zingiber officinale Rosc. (Zingiberaceae), has been used worldwide; however, for a long time, there has been no standard approbated internationally for its quality control. To establish an efficacious and combinational method and pattern recognition technique for quality...
  8. Protective effect of Basella alba and Carpolobia alba extracts against maneb-induced male infertility.

    Pharmaceutical Biology 52(1):97 (2014) PMID 24073857

    Male infertility is one of the leading causes of social frustration and marginalization, mainly in the developing world. It is attributed to many factors including exposure to agropesticides such as manganese ethylenebis (dithiocarbamate) (maneb), which is one of the most frequently used fungicides...
  9. AZT and emodin exhibit synergistic growth-inhibitory effects on K562/ADM cells by inducing S phase cell cycle arrest and suppressing MDR1 mR...

    Pharmaceutical Biology 51(12):1586 (2013) PMID 24004004

    These results show a synergistic growth-inhibitory effect of AZT and emodin in K562/ADM cells, which is achieved through S phase arrest. MDR1 might ultimately be responsible for these phenomena....
  10. Botanicals in Ribes nigrum bud-preparations: an analytical fingerprinting to evaluate the bioactive contribution to total phytocomplex.

    Pharmaceutical Biology 51(10):1282 (2013) PMID 23844599

    CONTEXT. Ribes nigrum L. (Grossulariaceae) is among the most commonly used herbal medicines and it is popularized for its alleged tonic effect and curative and restorative properties. The current practice of identifying herbal extracts is by measuring the concentration of the main botanicals. Their...