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Pharmaceutical Biology

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  1. Natural product drug discovery in the next millennium.

    Pharmaceutical Biology 39 Suppl 1:8 (2001) PMID 21554167

    Nature has been a source of medicinal agents for thousands of years, and an impressive number of modern drugs have been isolated from natural sources, many based on their use in traditional medicine. In the past century, however, an increasing role has been played by microorganisms in the produc...
  2. African ethnobotany and healthcare: emphasis on mozambique.

    Pharmaceutical Biology 39 Suppl 1:70 (2001) PMID 21554173

    The relationship between common medicinal plants and major health problems in Africa, specifically Mozambique, is presented here. Emphasis is given to plant species largely used to solve or slow down diarrhoea, malaria, respiratory, and sexual complaints. These diseases, together with malnutriti...
  3. Ensuring equitable benefits: the falealupo covenant and the isolation of anti-viral drug prostratin from a samoan medicinal plant.

    Pharmaceutical Biology 39 Suppl 1:33 (2001) PMID 21554169

    Equitable sharing of benefits from pharmacological development of biodiversity has been the topic of much discussion, but few concrete examples of recent plant-derived pharmaceuticals exist. The discovery of prostratin as an anti-viral phorbol isolated from healer preparations of the rain forest...
  4. A database model for integrating and facilitating collaborative ethnomedicinal research.

    Pharmaceutical Biology 39 Suppl 1:41 (2001) PMID 21554170

    A model for a database system that provides a standardized environment for submission, storage, and retrieval of ethnomedicinal data was developed. The model is based on object oriented database technology, and is suitable for not only storing data, digital images, sound and video, but also for ...
  5. Natural products research in latin america.

    Pharmaceutical Biology 39 Suppl 1:80 (2001) PMID 21554175

    The biodiversity found in Latin America is one of the richest in the world, yet its potential as a source of new pharmaceuticals has not been fully investigated. This paper will explore the present status of natural products research in 19 Latin American countries. Future research needs will be ...
  6. The ethnomedicinal uses of magnoliaceae from the southeastern United States as leads in drug discovery.

    Pharmaceutical Biology 39 Suppl 1:63 (2001) PMID 21554172

    In Asia and North America, members of the family Magnoliaceae have been and are presently used extensively in indigenous herbal medicine. Many taxa of the genus Magnolia produce lignans and sesquiterpene lactones, some with considerable in vitro bioactivities. This review focuses on selected nat...
  7. Preface.

    Pharmaceutical Biology 39 Suppl 1:6 (2001) PMID 21554166

  8. Ethnobotanical approaches of traditional medicine studies: some experiences from Asia.

    Pharmaceutical Biology 39 Suppl 1:74 (2001) PMID 21554174

    Ethnobotany, as a research field of science, has been widely used for the documentation of indigenous knowledge on the use of plants and for providing an inventory of useful plants from local flora in Asian countries. Plants that are used for traditional herbal medicine in different countries ar...
  9. On the cover.

    Pharmaceutical Biology 39 Suppl 1:5 (2001) PMID 21554165

  10. Modern screening techniques for plant extracts.

    Pharmaceutical Biology 39 Suppl 1:18 (2001) PMID 21554168

    In order to discover new bioactive compounds from plant sources which could become new leads or new drugs, extracts should be simultaneously evaluated by chemical screening and by various biological or pharmacological targets. Chemical screening using hyphenated techniques such as LC/UV and LC/M...