Annals of transplantation : quarterly of the Polish Transplantation Society
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Protection of heart and rejection of lymphocyte allografts from the same donor in recipients of donor-specific transfusions.
We reported previously that the DST (donor specific transfusion) recipients accept heart allografts but reject hyperacutely i.v. infused lymphocytes from the same as DST donor. The present study was devoted to elucidation of the mechanism of these divergent processes. Syngeneic BN hearts and mesente...
Microchimerism following allogeneic vascularized bone marrow transplantation--its possible role in induction of posttransplantation toleranc...
We have noticed that bone marrow transplanted in a vascularized limb graft providing a continuous supply of donor BMC may prolong the survival time of skin graft from the same donor. The question arises whether the raised microchimerism plays a role in the prolonged survival of skin allograft. The a...
Outcomes of renal transplantation in recipients with peak panel reactive antibody >30% under tacrolimus-based immunosuppression.
We examined outcomes of renal transplantation recipients with a peak PRA >30% and compared the outcomes of first and re-transplanted recipients. Survival outcomes between recipients of first transplants (n=68) and re-transplants (n=155) operated between June 1990 and August 2000 were compared. Sub-g...
Acute rejection and delayed graft function--risk factors of graft loss.
We studied the impact of these factors on graft outcome among 109 renal transplant recipients. All recipients were treated with triple drug protocol. The recipients were divided into two groups: I group included 57 patients with delayed graft function (DGF), II group included 52 patients with immedi...
Donation after cardiac death: the University of Wisconsin experience.
The objective of this analysis was to compare the results of transplantation of livers, pancreases, kidneys, and lungs from donation after cardiac death (DCD) donors to organs transplanted from donation after brain death (DBD) donors. From January 1984 through July 2000, outcomes of 382 DCD kidneys...
The mechanism of immunological "enhancement" in allografts--distribution of alloantigen and alloantiserum in the recipient.
We investigated the mechanism of the effect of administering the recipient donor cells and antibodies against these cells on prolongation of heart graft survival. AUGust rat (RTIc) cells and WIStar rat (RTIu) antibodies against AUG antigens were labeled with 51Cr and I 125, respectively. They were a...
Heart transplantation in the elderly: why cardiac transplantation does not need to be limited to younger patients but can be safely performe...
Within the last forty years, heart transplantation as the ultimate option for the treatment of end-stage heart disease has undergone dramatic changes and advances in operative techniques, postoperative care, immunosuppression, and rejection management which resulted in reduced morbidity and mortalit...
The effect of nephrectomy on the outcome of renal transplantation in patients with polycystic kidney disease.
Although various forms of polycystic kidney disease (PKD) account for up to 10% of patients requiring renal replacement therapy and severe complications may arise from these kidneys, no clear indications for pretransplant nephrectomy have been defined so far. A total of 104 renal transplants in thre...
Body distribution of syngeneic and allogeneic cells from vascularized bone marrow graft.
Renal transplants using expanded cadaver donor criteria.
We found: the incidence of delayed graft function of 63.9% vs 50.4% (P: 0.007); incidence of acute rejection of 66.1% vs 72.3% (P: 0.203). The patient survival at 1 and 5 years was 87% vs 92% and 81% vs 79%, respectively (P: 0.6809). The graft survival at 1 and 5 year was 74% vs 82% and 57% vs 59% (...