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- Csh, Rcgp, Proquest, Ovid from 2002, Ama, Aaas, Aacr, Endocrine, Nephrology, Oxford, Highwire from 1952, Oxford University Press, Rupress, Ingenta, and CSA
The prevalence of abnormal pulse wave velocity, pulse contour analysis and ankle-brachial index in patients with livedo reticularis: a contr...
We recruited 74 patients, of whom 41 had livedo: 16 APS, 9 APS with SLE and 16 with livedo (negative for aPL or lupus). The other group of 33 patients without livedo consisted of 10 APS, 8 APS with SLE and 15 with SLE only. Livedo was diagnosed and confirmed by a dermatologist. PWV was assessed in f...
Long-term efficacy and safety of pre-emptive maintenance therapy with rituximab in granulomatosis with polyangiitis: results from a single c...
Our study aims to evaluate the long-term efficacy and safety of chronic pre-emptive RTX therapy in GPA. Retrospective study of 35 GPA patients treated with RTX between April 2004 and September 2011 for active disease and maintenance. RTX was initiated as two 1 g infusions 2 weeks apart and thereafte...
Revisiting ANCA-associated vasculitis in systemic sclerosis: clinical, serological and immunogenetic factors.
We examined a clinical database of 2,200 patients with either limited or diffuse cutaneous systemic sclerosis (SSc). Patients with a confirmed diagnosis of vasculitis who were ANCA positive with either MPO or PR3 reactivity had their clinical features, serology, histology and HLA haplotypes examined...
Is the presence of sleep apnoea-hypopnoea syndrome a precursor for gout?
A subgroup of juvenile idiopathic arthritis patients who respond well to methotrexate are identified by the serum biomarker MRP8/14 protein.
We have demonstrated that high levels of baseline serum MRP8/14 have prognostic value in predicting a subgroup of patients whose arthritis will improve on MTX. Routine collection of serum prior to the start of medication would be a valuable step in collaborative validation of such biomarkers....
Early improvement of radiological signs of large-vessel inflammation in giant cell arteritis upon glucocorticoid treatment.
Efficacy and safety of leflunomide in DMARD-naive patients with early rheumatoid arthritis: comparison of a loading and a fixed-dose regimen...
Objective. To assess the efficacy of LEF administered with or without a loading dose in DMARD-naïve patients with early RA. Methods. This multicentre, double-blind, randomized clinical trial included adults with RA diagnosed within 6 months (ACR criteria). Patients were randomly selected to receive...
Long-term follow-up in lupus nephritis patients treated with rituximab--clinical and histopathological response.
Objective. To investigate the long-term clinical, histological and serological affects of B-cell-depleting therapy (BCDT) in patients with LN refractory to conventional treatment. Methods. Twenty-five patients, followed for a mean time of 36 months (9-95 months), were included. Renal disease activit...
Aerobic fitness after JDM--a long-term follow-up study.
We hypothesized that fitness (VO(2max)) is reduced compared with healthy controls in the years after active JDM. Methods. A maximal exercise test was performed using a cycle ergometer. Results were compared with those of sex- and age-matched healthy controls. Results. A total of 36 patients with JDM...