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Journal of Toxicology and Environmental Health, Part A: Current Issues

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  1. Kidney biomarkers associated with blood lead, mercury, and cadmium in premenopausal women: a prospective cohort study.

    Journal of Toxicology and Environmental Health,... 78(2):119 (2015) PMID 25424620 PMCID PMC4246415

    Certain metals are harmful to the kidney and liver at high levels, but associations with functional biomarkers at low exposure levels among premenopausal women apparently has not been evaluated. Healthy, regularly menstruating women (n = 259) were followed for up to 2 menstrual cycles with up to...
  2. Risk factors for lead exposure in adult population in southern Brazil.

    Journal of Toxicology and Environmental Health,... 78(2):92 (2015) PMID 25424618

    In Brazil there is no systematic evaluation to access blood lead levels (BLL) in the general population and few studies with adults have been published. The aim of this study was to examine the socioeconomic, environmental, and lifestyle determinants of BLL in the adult Brazilian population. In ...
  3. Organic and inorganic fractions of diesel exhaust particles produce changes in mucin profile of mouse trachea explants.

    Journal of Toxicology and Environmental Health,... 78(4):215 (2015) PMID 25674825

    Diesel exhaust particles (DEP) contain organic and inorganic elements that produce damage to the respiratory epithelium. The aim of this study was to determine the mucus profile of tracheal explants exposed to either crude diesel exhaust particles (DEP) or DEP treated with nitric acid (DEP/NA), ...
  4. Scales of freshwater fish Labeo rohita as bioindicators of water pollution in Tung Dhab Drain, Amritsar, Punjab, India.

    Journal of Toxicology and Environmental Health,... 78(6):388 (2015) PMID 25734766

    This study examined the impact of municipal wastewater on scale morphology of freshwater fish Labeo rohita. Fish were exposed to sublethal concentrations (17.7, 26.6, or 35.4%) of municipal wastewater for durations of 15, 30, and 60 d. Recovery experiments were also performed for a duration of 6...
  5. Comparative analysis of the relationship between trichloroethylene metabolism and tissue-specific toxicity among inbred mouse strains: kidney effects.

    Journal of Toxicology and Environmental Health,... 78(1):32 (2015) PMID 25424545 PMCID PMC4281933

    Trichloroethylene (TCE) is a well-known environmental and occupational toxicant that is classified as carcinogenic to humans based on the epidemiological evidence of an association with higher risk of renal-cell carcinoma. A number of scientific issues critical for assessing human health risks f...
  6. Essential and toxic elements in clays for pharmaceutical and cosmetic use.

    Journal of Toxicology and Environmental Health,... 78(5):316 (2015) PMID 25734627

    Essential and toxic elements (Al, Si, P, S, K, Ca, Ti, Mn, Fe, Ni, Cu, Zn, As, Br, Rb, Sr, Ba, Cd, Ce, Nd, Pb, U, Th, and La) were determined by energy-dispersive polarized x-ray fluorescence spectrometry (EDPXRF) in 15 samples of clay materials for pharmaceutical and cosmetic use. The investiga...
  7. Fine particulate air pollution and outpatient department visits for headache in Taipei, Taiwan.

    Journal of Toxicology and Environmental Health,... 78(8):506 (2015) PMID 25849767

    This study was undertaken to determine whether there was an association between fine particle matter (PM(2.5)) levels and daily outpatient department visits (OPD) for headaches in Taipei, Taiwan. Daily OPD visits for headaches and ambient air pollution data for Taipei were obtained for the perio...
  8. Effects of Lead Exposure and Genetic Polymorphisms on ALAD and GPx Activities in Brazilian Battery Workers.

    Journal of Toxicology and Environmental Health,... 78(16):1073 (2015) PMID 26275098

    Lead (Pb) is a toxic metal that is widely used by metallurgical industries such as car battery recycling. Exposure to the metal may modify the redox status of the cells and consequently result in changes in activities of important enzymes such as delta-aminolevulinic acid dehydratase (ALAD) and ...
  9. 4-Hydroxynonenal: A Superior Oxidative Biomarker Compared to Malondialdehyde and Carbonyl Content Induced by Carbon Tetrachloride in Rats.

    Journal of Toxicology and Environmental Health,... 78(16):1051 (2015) PMID 26252470

    Carbon tetrachloride (CCl4), a halogenated substance that generates free radical species during metabolism in vivo, induces hepatotoxicity, produces oxidative DNA damage, and increased levels of protein carbonyl, malondialdehyde (MDA), and 4-hydroxynonenal (4-HNE). In this study, Sprague-Dawley ...
  10. Prenatal exposure to the phytoestrogen daidzein resulted in persistent changes in ovarian surface epithelial cell height, folliculogenesis, and estrus phase length in adult Sprague-Dawley rat offspring.

    Journal of Toxicology and Environmental Health,... 78(10):635 (2015) PMID 26039681

    Daidzein (DZ), an isoflavone with the potential to interfere with estrogen signaling, is found in soy products, which have gained popularity due to purported beneficial effects on the cardiovascular and skeletal systems and potential antineoplastic properties. However, the ingestion of phytoestr...