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Journal of Toxicology and Environmental Health, Part A: Current Issues

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  1. Hematological and hepatic alterations in brazilian population heavily exposed to organochlorine pesticides.

    Journal of Toxicology and Environmental Health,... 78(8):534 (2015) PMID 25849770

    The aim of this study was to investigate the frequency of hematological and hepatic alterations and possible association with serum levels of beta-hexachlorocyclohexane (beta-HCH), p,p'-DDE, and hexachlorobenzene (HCB) among residents in an area heavily contaminated with organochlorine (OC) pest...
  2. Risk factors for lead exposure in adult population in southern Brazil.

    Journal of Toxicology and Environmental Health,... 78(2):92 (2015) PMID 25424618

    In Brazil there is no systematic evaluation to access blood lead levels (BLL) in the general population and few studies with adults have been published. The aim of this study was to examine the socioeconomic, environmental, and lifestyle determinants of BLL in the adult Brazilian population. In ...
  3. Comparative analysis of the relationship between trichloroethylene metabolism and tissue-specific toxicity among inbred mouse strains: kidney effects.

    Journal of Toxicology and Environmental Health,... 78(1):32 (2015) PMID 25424545 PMCID PMC4281933

    Trichloroethylene (TCE) is a well-known environmental and occupational toxicant that is classified as carcinogenic to humans based on the epidemiological evidence of an association with higher risk of renal-cell carcinoma. A number of scientific issues critical for assessing human health risks f...
  4. Organic and inorganic fractions of diesel exhaust particles produce changes in mucin profile of mouse trachea explants.

    Journal of Toxicology and Environmental Health,... 78(4):215 (2015) PMID 25674825

    Diesel exhaust particles (DEP) contain organic and inorganic elements that produce damage to the respiratory epithelium. The aim of this study was to determine the mucus profile of tracheal explants exposed to either crude diesel exhaust particles (DEP) or DEP treated with nitric acid (DEP/NA), ...
  5. Essential and toxic elements in clays for pharmaceutical and cosmetic use.

    Journal of Toxicology and Environmental Health,... 78(5):316 (2015) PMID 25734627

    Essential and toxic elements (Al, Si, P, S, K, Ca, Ti, Mn, Fe, Ni, Cu, Zn, As, Br, Rb, Sr, Ba, Cd, Ce, Nd, Pb, U, Th, and La) were determined by energy-dispersive polarized x-ray fluorescence spectrometry (EDPXRF) in 15 samples of clay materials for pharmaceutical and cosmetic use. The investiga...
  6. Scales of freshwater fish Labeo rohita as bioindicators of water pollution in Tung Dhab Drain, Amritsar, Punjab, India.

    Journal of Toxicology and Environmental Health,... 78(6):388 (2015) PMID 25734766

    This study examined the impact of municipal wastewater on scale morphology of freshwater fish Labeo rohita. Fish were exposed to sublethal concentrations (17.7, 26.6, or 35.4%) of municipal wastewater for durations of 15, 30, and 60 d. Recovery experiments were also performed for a duration of 6...
  7. Kidney biomarkers associated with blood lead, mercury, and cadmium in premenopausal women: a prospective cohort study.

    Journal of Toxicology and Environmental Health,... 78(2):119 (2015) PMID 25424620 PMCID PMC4246415

    Certain metals are harmful to the kidney and liver at high levels, but associations with functional biomarkers at low exposure levels among premenopausal women apparently has not been evaluated. Healthy, regularly menstruating women (n = 259) were followed for up to 2 menstrual cycles with up to...
  8. In vitro assessment of mutagenic and genotoxic effects of coumarin derivatives 6,7-dihydroxycoumarin and 4-methylesculetin.

    Journal of Toxicology and Environmental Health,... 78(2):109 (2015) PMID 25424619

    Coumarins are naturally occurring compounds, widely distributed throughout the plant kingdom (Plantae), and possess important pharmacological properties, including inhibition of oxidative stress. In this context, newly synthesized coumarin compounds are being produced due to their potent antioxi...
  9. Chromosome damage, apoptosis, and necrosis in exfoliated cells of oral mucosa from androgenic anabolic steroids users.

    Journal of Toxicology and Environmental Health,... 78(2):67 (2015) PMID 25424616

    The aim of this study was to evaluate the potential of the androgenic anabolic steroids (AAS) for inducing chromosome damage, apoptosis, and necrosis, using the micronucleus test on exfoliated cells from the oral mucosa of AAS users. The sample consisted of 55 male individuals, practitioners of ...
  10. Phthalate concentrations in personal care products and the cumulative exposure to female adults and infants in shanghai.

    Journal of Toxicology and Environmental Health,... 78(5):325 (2015) PMID 25734628

    Phthalate esters (PE) are synthetic chemicals widely used in industry, and have been detected in personal care products (PCP). Recent findings of human reports demonstrated endocrine-disrupting action associated with phthalate exposures. The aims of this study were to (1) measure levels of 11 PE...