Current Diabetes Reports
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- Metapress, Gale, and Springer
Lifestyle interventions to reduce diabetes and cardiovascular disease risk among children.
Diseases once associated with older adulthood, type 2 diabetes and cardiovascular disease, are increasingly diagnosed in children and adolescents. Interventions designed to assist adults in modifying dietary and physical activity habits have been shown to help prevent the development of type 2 diabe...
Role of B lymphocytes in the pathogenesis of type 1 diabetes.
We review extant findings implicating B cells in T1D in mice and men....
Getting a technology-based diabetes intervention ready for prime time: a review of usability testing studies.
We conducted a narrative review of peer-reviewed articles published from 2009 to 2013 that tested the usability of a web- or mobile-delivered system/application designed to educate and support patients with diabetes. Overall, the 23 papers included in our review used mixed (n = 11), descriptive quan...
New insight on human type 1 diabetes biology: nPOD and nPOD-transplantation.
The Juvenile Diabetes Research Foundation (JDRF) Network for Pancreatic Organ Donors with Diabetes (JDRF nPOD) was established to obtain human pancreata and other tissues from organ donors with type 1 diabetes (T1D) in support of research focused on disease pathogenesis. Since 2007, nPOD has recover...
The relationship and potential mechanistic pathways between sleep disturbances and maternal hyperglycemia.
This paper reviews recent work investigating the influence of sleep disturbances on maternal hyperglycemia, particularly gestational diabetes mellitus (GDM). The incidence and prevalence of hyperglycemia are increasing worldwide, which is cause for concern because GDM and even mild hyperglycemia are...
Transition readiness in adolescents and emerging adults with diabetes: the role of patient-provider communication.
Transition from pediatric to adult care represents a high risk period for adolescents and emerging adults with diabetes. Fundamental differences between pediatric and adult care delivery models may contribute to increased risk for poor health outcomes. This review provides a brief overview of models...
Moving on from GWAS: functional studies on the G6PC2 gene implicated in the regulation of fasting blood glucose.
Genome-wide association studies (GWAS) have shown that single-nucleotide polymorphisms (SNPs) in G6PC2 are the most important common determinants of variations in fasting blood glucose (FBG) levels. Molecular studies examining the functional impact of these SNPs on G6PC2 gene transcription and splic...
Hypoglycemia in patients with type 1 diabetes: epidemiology, pathogenesis, and prevention.
Hypoglycemia is uncommon in the general, nondiabetic population but occurs frequently in persons with diabetes treated with insulin or insulin secretagogues. Thus, iatrogenic hypoglycemia explains the majority of cases among persons with type 1 diabetes (T1DM). Since T1DM is characterized by absolut...
Erratum to: The Role of Community Health Workers in Diabetes: Update on Current Literature.
Uric acid lowering to prevent kidney function loss in diabetes: the preventing early renal function loss (PERL) allopurinol study.
Diabetic kidney disease causes significant morbidity and mortality among people with type 1 diabetes (T1D). Intensive glucose and blood pressure control have thus far failed to adequately curb this problem and therefore a major need for novel treatment approaches exists. Multiple observations link s...