Current Diabetes Reports
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- Metapress, Gale, and Springer
Glycemic targets in pregnancies affected by diabetes: historical perspective and future directions.
The definition of optimal glycemic control in pregnancies affected by diabetes remains enigmatic. Diabetes phenotypes are heterogeneous. Moreover, fetal macrosomia insidiously occurs even with excellent glycemic control. Current blood glucose (BG) targets (FBG ≤95, 1-h post-prandial <120 m...
Ultra widefield fundus imaging for diabetic retinopathy.
For decades, the standard method for screening and grading severity of diabetic retinal disease has relied upon a montage of photographs using normal angle fundus cameras. With the development of ultrawide field (UWF) fundus imaging, more of the retina can be imaged with fewer pictures, less depende...
Environmental endocrine disruption of energy metabolism and cardiovascular risk.
Rates of metabolic diseases have increased at an astounding rate in recent decades. Even though poor diet and physical inactivity are central drivers, these lifestyle changes alone fail to fully account for the magnitude and rapidity of the epidemic. Thus, attention has turned to identifying novel r...
The sum of many parts: potential mechanisms for improvement in glucose homeostasis after bariatric surgery.
We discuss the various types of surgical interventions and the multitude of factors that potentially mediate the effects on glycemia, such as altered delivery of nutrients to the distal ileum, duodenal exclusion, gut hormone changes, bile acid reabsorption, and amino acid metabolism. Accumulating ev...
Risk vs benefit in diabetes pharmacotherapy: a rational approach to choosing pharmacotherapy in type 2 diabetes.
We review the commonly prescribed pharmacotherapy options with attention to recently published information and provide a rational approach to choice of therapy....
Novel targets against retinal angiogenesis in diabetic retinopathy.
Proliferative diabetic retinopathy (PDR), characterized by pathologic retinal angiogenesis, is a major cause of blindness in the USA and globally. Treatments targeting vascular endothelial growth factor (VEGF) have emerged as a beneficial part of the therapeutic armamentarium for this condition, hig...
Dual renin-angiotensin-aldosterone system blockade for diabetic kidney disease.
Blockade of the renin-angiotensin-aldosterone system (RAAS) prevents the development and progression of diabetic kidney disease (DKD). It is controversial whether the simultaneous use of two RAAS inhibitors (ie, dual RAAS blockade) further improves renal outcomes. This review examines the scientific...
Current concepts about chromium supplementation in type 2 diabetes and insulin resistance.
Best strategies for hypertension management in type 2 diabetes and obesity.
The Eurodiab study: what has this taught us about diabetic peripheral neuropathy?
Apart from tight blood glucose control, no other treatments have been shown to retard the progression of diabetic peripheral neuropathy (DPN). Therefore, identifying potential risk factors for DPN is important, particularly if they are modifiable. The Eurodiab baseline DPN study found a prevalence o...