Current Molecular Medicine
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Clinical assessment of carotid atherosclerosis inflammation by positron emission tomography.
Stroke caused by carotid atherosclerosis is a leading cause of mortality and the leading cause of disability in the developed world. For carotid plaques within the neurovascular territory of a recent stroke or transient ischaemic attack, surgical removal of the plaque (endarterectomy) has been clear...
Hrd1 facilitates tau degradation and promotes neuron survival.
We showed an inverse relationship between endoplasmic reticulum membrane ubiquitin ligase (E3) Hrd1 expression and p-tau accumulation in the hippocampal neurons of AD, and proposed that Hrd1 may be a negative regulator of p-tau. This notion was further supported by in vitro study demonstrating that...
Pharmacotherapies for glaucoma.
DNA repair pathways and human metastatic malignant melanoma.
Pigment epithelium-derived factor (PEDF) in health and disease.
Pneumolysin: a double-edged sword during the host-pathogen interaction.
Epidemiology and clinical presentation of stress-related peptic damage and chronic peptic ulcer.
Molecular genetics and biomarkers of polyglutamine diseases.
Ca2+ signaling, mitochondria and cell death.
Mitochondria and human cancer.