Journal of Cellular and Molecular Medicine
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- Ingenta, Ovid, Proquest, Wiley from 2000, CSA, and Rcgp
Protein kinase Cδ promotes proliferation and induces malignant transformation in skeletal muscle.
We investigated the isoform-specific roles of certain protein kinase C (PKC) isoforms in the regulation of skeletal muscle growth. Here, we provide the first intriguing functional evidence that nPKCδ (originally described as an inhibitor of proliferation in various cells types) is a key player in pr...
Toll-like receptor stimulation differentially regulates vasoactive intestinal peptide type 2 receptor in macrophages.
Phenazopyridine induces and synchronizes neuronal differentiation of embryonic stem cells.
We developed a screening approach to identify small organic molecules driving neuronal differentiation of ES cells. For this purpose, we used a lentivector carrying a dual luciferase reporter system to engineer an ES cell line which allowed us to screen for small organic molecules enhancing neuronal...
Inhibition of DNA methyltransferase induces G2 cell cycle arrest and apoptosis in human colorectal cancer cells via inhibition of JAK2/STAT3...
We demonstrate that 5-aza-dc suppresses growth of CRC cells, and induces G2 cell cycle arrest and apoptosis through regulation of downstream targets of JAK2/STAT3/STAT5 signaling including Bcl-2, p16(ink4a), p21(waf1/cip1), and p27(kip1). Although 5-aza-dc did not significantly inhibit cell invasion...
E2F1 represses beta-catenin/TCF activity by direct upregulation of Siah1.
Still life: cerebellar neurons in early apoptosis
Beta-cell dysfunctions and insulin resistance in subjects with increased risk for type 2 diabetes mellitus
Letter to the Editor