Clinical Research in Cardiology
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Chronic protection against ischemia and reperfusion-induced endothelial dysfunction during therapy with different organic nitrates.
Ischemic and pharmacologic preconditioning have great clinical potential, but it remains unclear whether their effects can be maintained over time during repeated exposure.We have previously demonstrated that the acute protective effect of nitroglycerin (GTN) is attenuated during repeated daily admin...
Complement anaphylatoxin C3a as a novel independent prognostic marker in heart failure.
Results of the present study showed that complement activation is strongly linked to unfavourable outcomes in heart failure. High levels of anaphylatoxin C3a predicted re-hospitalization, cardiovascular events and mortality in adjusted survival model. Increased C3a levels were associated with biomar...
Relationship and prognostic value of microvascular obstruction and infarct size in ST-elevation myocardial infarction as visualized by magne...
In contrast to infarct size, MO is associated with adverse clinical outcome after STEMI even after adjustment for other CMR parameters. However, MO/infarct size is a more powerful predictor for long-term outcome after STEMI than either parameter alone....
Incidence and distribution of occluded culprit arteries and impact of coronary collaterals on outcome in patients with non-ST-segment elevat...
We examined 448 consecutive NSTEMI patients within 72 h of symptom onset. All patients underwent early invasive angiography plus optimal medical therapy. We compared clinical characteristics and 30-days/6-month major adverse cardiovascular events (MACE) between patients with OCA and non-OCA. The sec...
Intracardial dislocation of a cranio-peritoneal shunt in a 6-year-old boy.
Admission C-reactive protein and short- as well as long-term mortality in diabetic versus non-diabetic patients with incident myocardial inf...
Carotid artery interventions for restenosis after prior stenting: is it different from interventions of de novo lesions? Results from the ca...
Two concomitant arrhythmias in a transplanted heart.
Long-term follow-up of acute changes in coronary artery diameter caused by Kawasaki disease: risk factors for development of stenotic lesion...
After KD, patients with a coronary aneurysm size >5.0 mm need close follow-up assessments because of an elevated risk for the development of coronary stenotic lesions. In case of new and even unspecific ECG changes, coronary imaging modalities (angiography, MRI) have to be considered. Therapy option...
Biventricular repair despite hypoplastic tricuspid valve and right ventricle.