Nature Communications

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  1. Genetic blueprint of the zoonotic pathogen Toxocara canis.

    Nature Communications 6:6145 (2015) PMID 25649139 PMCID PMC4327413

    Toxocara canis is a zoonotic parasite of major socioeconomic importance worldwide. In humans, this nematode causes disease (toxocariasis) mainly in the under-privileged communities in developed and developing countries. Although relatively well studied from clinical and epidemiological perspecti...
  2. A fatty acid-dependent hypothalamic-DVC neurocircuitry that regulates hepatic secretion of triglyceride-rich lipoproteins.

    Nature Communications 6:5970 (2015) PMID 25580573

    The brain emerges as a regulator of hepatic triglyceride-rich very-low-density lipoproteins (VLDL-TG). The neurocircuitry involved as well as the ability of fatty acids to trigger a neuronal network to regulate VLDL-TG remain unknown. Here we demonstrate that infusion of oleic acid into the medi...
  3. Emergence of coherence in the charge-density wave state of 2H-NbSe2.

    Nature Communications 6:6313 (2015) PMID 25687135

    A charge-density wave (CDW) state has a broken symmetry described by a complex order parameter with an amplitude and a phase. The conventional view, based on clean, weak-coupling systems, is that a finite amplitude and long-range phase coherence set in simultaneously at the CDW transition temper...
  4. Strong interactive growth behaviours in solution-phase synthesis of three-dimensional metal oxide nanostructures.

    Nature Communications 6:6325 (2015) PMID 25687241

    Wet-chemical synthesis is a promising alternative to the conventional vapour-phase method owing to its advantages in commercial-scale production at low cost. Studies on nanocrystallization in solution have suggested that growth rate is commonly affected by the size and density of surrounding cry...
  5. The polymeric mucin Muc5ac is required for allergic airway hyperreactivity.

    Nature Communications 6:6281 (2015) PMID 25687754

    In asthma, airflow obstruction is thought to result primarily from inflammation-triggered airway smooth muscle (ASM) contraction. However, anti-inflammatory and smooth muscle-relaxing treatments are often temporary or ineffective. Overproduction of the mucin MUC5AC is an additional disease featu...
  6. Visualization of molecular fluorescence point spread functions via remote excitation switching fluorescence microscopy.

    Nature Communications 6:6287 (2015) PMID 25687887

    The enhancement of molecular absorption, emission and scattering processes by coupling to surface plasmon polaritons on metallic nanoparticles is a key issue in plasmonics for applications in (bio)chemical sensing, light harvesting and photocatalysis. Nevertheless, the point spread functions for...
  7. Bandgap tunability at single-layer molybdenum disulphide grain boundaries.

    Nature Communications 6:6298 (2015) PMID 25687991

    Two-dimensional transition metal dichalcogenides have emerged as a new class of semiconductor materials with novel electronic and optical properties of interest to future nanoelectronics technology. Single-layer molybdenum disulphide, which represents a prototype two-dimensional transition metal...
  8. Metabolic cross-feeding via intercellular nanotubes among bacteria.

    Nature Communications 6:6238 (2015) PMID 25703793

    Bacteria frequently exchange metabolites by diffusion through the extracellular environment, yet it remains generally unclear whether bacteria can also use cell-cell connections to directly exchange nutrients. Here we address this question by engineering cross-feeding interactions within and bet...
  9. A mechanically sensitive cell layer regulates the physical properties of the Arabidopsis seed coat.

    Nature Communications 6:6382 (2015) PMID 25702924

    Endogenous mechanical stresses regulate plant growth and development. Tensile stress in epidermal cells affects microtubule reorientation and anisotropic cell wall deposition, and mechanical stimulus at the meristem regulates trafficking and polar localization of auxin transporters. However, the...
  10. Formation of titanium monoxide (001) single-crystalline thin film induced by ion bombardment of titanium dioxide (110).

    Nature Communications 6:6147 (2015) PMID 25707936

    A plethora of technological applications justify why titanium dioxide is probably the most studied oxide, and an optimal exploitation of its properties quite frequently requires a controlled modification of the surface. Low-energy ion bombardment is one of the most extended techniques for this p...
  11. A molecular nematic liquid crystalline material for high-performance organic photovoltaics.

    Nature Communications 6:6013 (2015) PMID 25586307

    Solution-processed organic photovoltaic cells (OPVs) hold great promise to enable roll-to-roll printing of environmentally friendly, mechanically flexible and cost-effective photovoltaic devices. Nevertheless, many high-performing systems show best power conversion efficiencies (PCEs) with a thi...
  12. Size dependence of phase transitions in aerosol nanoparticles.

    Nature Communications 6:5923 (2015) PMID 25586967

    Phase transitions of nanoparticles are of fundamental importance in atmospheric sciences, but current understanding is insufficient to explain observations at the nano-scale. In particular, discrepancies exist between observations and model predictions of deliquescence and efflorescence transiti...
  13. Cytoplasmic TAF2-TAF8-TAF10 complex provides evidence for nuclear holo-TFIID assembly from preformed submodules.

    Nature Communications 6:6011 (2015) PMID 25586196

    General transcription factor TFIID is a cornerstone of RNA polymerase II transcription initiation in eukaryotic cells. How human TFIID-a megadalton-sized multiprotein complex composed of the TATA-binding protein (TBP) and 13 TBP-associated factors (TAFs)-assembles into a functional transcription...
  14. Erratum: Ferroelectrically driven spatial carrier density modulation in graphene.

    Nature Communications 6:6371 (2015) PMID 25666202

  15. Observation of long-lived interlayer excitons in monolayer MoSe2-WSe2 heterostructures.

    Nature Communications 6:6242 (2015) PMID 25708612

    Van der Waals bound heterostructures constructed with two-dimensional materials, such as graphene, boron nitride and transition metal dichalcogenides, have sparked wide interest in device physics and technologies at the two-dimensional limit. One highly coveted heterostructure is that of differi...
  16. Controlling the direction of rectification in a molecular diode.

    Nature Communications 6:6324 (2015) PMID 25727708

    A challenge in molecular electronics is to control the strength of the molecule-electrode coupling to optimize device performance. Here we show that non-covalent contacts between the active molecular component (in this case, ferrocenyl of a ferrocenyl-alkanethiol self-assembled monolayer (SAM)) ...
  17. Structure and function of lysosomal phospholipase A2 and lecithin:cholesterol acyltransferase.

    Nature Communications 6:6250 (2015) PMID 25727495

    Lysosomal phospholipase A2 (LPLA2) and lecithin:cholesterol acyltransferase (LCAT) belong to a structurally uncharacterized family of key lipid-metabolizing enzymes responsible for lung surfactant catabolism and for reverse cholesterol transport, respectively. Whereas LPLA2 is predicted to under...
  18. Visualizing the non-equilibrium dynamics of photoinduced intramolecular electron transfer with femtosecond X-ray pulses.

    Nature Communications 6:6359 (2015) PMID 25727920

    Ultrafast photoinduced electron transfer preceding energy equilibration still poses many experimental and conceptual challenges to the optimization of photoconversion since an atomic-scale description has so far been beyond reach. Here we combine femtosecond transient optical absorption spectros...
  19. Methane hydrate formation in confined nanospace can surpass nature.

    Nature Communications 6:6432 (2015) PMID 25728378

    Natural methane hydrates are believed to be the largest source of hydrocarbons on Earth. These structures are formed in specific locations such as deep-sea sediments and the permafrost based on demanding conditions of high pressure and low temperature. Here we report that, by taking advantage of...
  20. Predicting clinical response to anticancer drugs using an ex vivo platform that captures tumour heterogeneity.

    Nature Communications 6:6169 (2015) PMID 25721094

    Predicting clinical response to anticancer drugs remains a major challenge in cancer treatment. Emerging reports indicate that the tumour microenvironment and heterogeneity can limit the predictive power of current biomarker-guided strategies for chemotherapy. Here we report the engineering of p...