BioMed Research International
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- Hindawi Publishing Corporation
MicroRNAs: promising new antiangiogenic targets in cancer.
MicroRNAs are one class of small, endogenous, non-coding RNAs that are approximately 22 nucleotides in length; they are very numerous, have been phylogenetically conserved, and involved in biological processes such as development, differentiation, cell proliferation, and apoptosis. MicroRNAs contrib...
Genetics of Alzheimer's disease.
We review the known genetics of early- and late-onset Alzheimer's disease....
Aorta structural alterations in term neonates: the role of birth and maternal characteristics.
To evaluate the influence of selected maternal and neonatal characteristics on aorta walls in term, appropriately grown-for-gestational age newborns. Age, parity, previous abortions, weight, height, body mass index before and after delivery, smoking, and history of hypertension, of diabetes, of card...
Development of bioadhesive chitosan superporous hydrogel composite particles based intestinal drug delivery system.
Bioadhesive superporous hydrogel composite (SPHC) particles were developed for an intestinal delivery of metoprolol succinate and characterized for density, porosity, swelling, morphology, and bioadhesion studies. Chitosan and HPMC were used as bioadhesive and release retardant polymers, respectivel...
Antibodies against food antigens in patients with autistic spectrum disorders.
Immune system of some autistic patients could be abnormally triggered by gluten/casein assumption. The prevalence of antibodies to gliadin and milk proteins in autistic children with paired/impaired intestinal permeability and under dietary regimen either regular or restricted is reported. 162 ASDs...
Ischemia-reperfusion injury and volatile anesthetics.
Ischemia-reperfusion injury (IRI) is induced as a result of reentry of the blood and oxygen to ischemic tissue. Antioxidant and some other drugs have protective effect on IRI. In many surgeries and clinical conditions IRI is counteract inevitable. Some anesthetic agents may have a protective role in...
Antimicrobial activity of artemisinin and precursor derived from in vitro plantlets of Artemisia annua L.
Artemisia annua L., a medicinal herb, produces secondary metabolites with antimicrobial property. In Malaysia due to the tropical hot climate, A. annua could not be planted for production of artemisinin, the main bioactive compound. In this study, the leaves of three in vitro A. annua L. clones were...
Microtexturing of the conductive PEDOT:PSS polymer for superhydrophobic organic electrochemical transistors.
We integrated superhydrophobic patterns with the conducting polymer PEDOT:PSS, one of the most used polymers in organic electronics because highly sensitive to ionized species in solution. In doing so, we combined geometry and materials science to obtain an advanced device where, on account of the s...
Drug resistance mechanisms of Mycoplasma pneumoniae to macrolide antibiotics.
Throat swabs from children with suspected Mycoplasma pneumoniae (M. pneumoniae) infection were cultured for the presence of M. pneumoniae and its species specificity using the 16S rRNA gene. Seventy-six M. pneumoniae strains isolated from 580 swabs showed that 70 were erythromycin resistant with min...
D-glucosamine promotes transfection efficiency during electroporation.
D-Glucosamine is a useful medicament in various fields of medicine and dentistry. With respect to stability of the cell membrane, it has been reported that bradykinin-induced nociceptive responses are significantly suppressed by the direct application of D-glucosamine. Electroporation is usually use...