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BioMed Research International

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Hindawi Publishing Corporation

  1. Exercise improves immune function, antidepressive response, and sleep quality in patients with chronic primary insomnia.

    BioMed Research International 2014:498961 (2014) PMID 25328886 PMCID PMC4189910

    The aim of this study was to evaluate the effects of moderate aerobic exercise training on sleep, depression, cortisol, and markers of immune function in patients with chronic primary insomnia. Twenty-one sedentary participants (16 women aged 44.7 ± 9 years) with chronic primary insomnia completed a...
  2. Tumor suppression and promotion by autophagy.

    BioMed Research International 2014:603980 (2014) PMID 25328887 PMCID PMC4189854

    We will focus the discussion on this ambiguous role of autophagy in the development and progression of cancer....
  3. Protective effect of a prime-boost strategy with the Ts87 vaccine against Trichinella spiralis infection in mice.

    BioMed Research International 2014:326860 (2014) PMID 25250316 PMCID PMC4164511

    Trichinellosis is a widespread zoonosis primarily caused by Trichinella spiralis. Mucosal immunity is crucial for preventing Trichinella spiralis infection. In our previous study, a DNA vaccine with the Trichinella antigen Ts87 delivered by an attenuated Salmonella typhimurium elicited partial prote...
  4. Hypervolemia for hypertension pathophysiology: a population-based study.

    BioMed Research International 2014:895401 (2014) PMID 25177700 PMCID PMC4142663

    Hypertension and hypervolemia relationship was proven among renal disease, although it is not known in normal population. Present study determines the fluid distribution defects in relation to blood pressure. In a population-based survey in Turkey demographics, height, weight, blood pressure, urine...
  5. Impact of seasons and dioecy on therapeutic phytoconstituents of Tinospora cordifolia, a Rasayana drug.

    BioMed Research International 2014:902138 (2014) PMID 25177701 PMCID PMC4142535

    Tinospora cordifolia (Thunb.) Miers, Menispermaceae, is a dioecious creeper, commonly known as "Giloe" or "Guduchi" with significant medicinal importance in the traditional systems of medicine. It is designated as Rasayana drug in Ayurveda and recommended for a number of diseases and also as adaptog...
  6. Negative regulation of GADD34 on myofibroblasts during cutaneous wound healing.

    BioMed Research International 2014:137049 (2014) PMID 25210702 PMCID PMC4156997

    We subjected WT and GADD34(-/-) mice to dermal wound healing. Here we show that GADD34(-/-) mice exhibited accelerated wound closure compared with WT mice. In addition, GADD34(-/-) mice showed increased number of myofibroblasts, elevated collagen production, and decreased cell apoptosis during wound...
  7. Accuracy of patient specific cutting blocks in total knee arthroplasty.

    BioMed Research International 2014:562919 (2014) PMID 25254210 PMCID PMC4164815

    We obtained a success rate of 92.9% for the HKA, 98.2% for the PTA, and 99.1% for the DFA. The TS showed postoperative results of 2.86±2.02° (mean change 1.76±2.85°). PSCBs for TKA seem to restore the overall leg alignment. Our data suggest that each individual component can be implanted accurately...
  8. Targeting mast cells tryptase in tumor microenvironment: a potential antiangiogenetic strategy.

    BioMed Research International 2014:154702 (2014) PMID 25295247 PMCID PMC4177740

    We focused on molecular mechanisms of three tryptase inhibitors (gabexate mesylate, nafamostat mesylate, and tranilast) in order to consider their prospective role in cancer therapy....
  9. Model of break-bone fever via beta-derivatives.

    BioMed Research International 2014:523159 (2014) PMID 25295263 PMCID PMC4177741

    We modelled the well-known infectious disease called break-bone fever or the dengue fever. We presented the endemic equilibrium points under certain conditions of the physical parameters included in the model. We made use of an iteration method to solve the extended model. To show the efficiency of...
  10. Effects of soft denture liners on L929 fibroblasts, HaCaT keratinocytes, and RAW 264.7 macrophages.

    BioMed Research International 2014:840613 (2014) PMID 25295276 PMCID PMC4177820

    The effects of six soft liners (Ufi Gel P (UG), Sofreliner S (SR), Durabase Soft (D), Trusoft (T), Coe Comfort (CC), and Softone (ST)) on L929, HaCat, and RAW 264.7 cells were investigated. Eluates (24 and 48 h) from the materials were applied on the cells and the viability, type of cell death, and...