BioMed Research International
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- Hindawi Publishing Corporation
Association of CHMP4B and Autophagy with Micronuclei: Implications for Cataract Formation.
We show that the ESCRT-III subunit CHMP4B not only localizes to normal cytokinetic bridges but also to chromosome bridges and micronuclei, the latter surrounded by lysosomes and autophagosomes. Moreover, CHMP4B can be co-immunoprecipitated with chromatin. Interestingly, a CHMP4B mutation associated...
Red cell distribution width as a prognostic indicator in pediatric heart disease and after surgery.
Background. Red cell distribution width (RDW) is an important marker which reflects inflammatory activity in many chronic diseases. The objective of this study is to investigate the impact of RDW on morbidity and mortality before and after pediatric congenital heart surgery. Methods. 107 patients wi...
Antihypertensive action of allantoin in animals.
We suggest that allantoin, as I-1R agonist, has the potential to develop as a new therapeutic agent for hypertension in the future....
Genetics of Alzheimer's disease.
We review the known genetics of early- and late-onset Alzheimer's disease....
Aorta structural alterations in term neonates: the role of birth and maternal characteristics.
To evaluate the influence of selected maternal and neonatal characteristics on aorta walls in term, appropriately grown-for-gestational age newborns. Age, parity, previous abortions, weight, height, body mass index before and after delivery, smoking, and history of hypertension, of diabetes, of card...
Development of bioadhesive chitosan superporous hydrogel composite particles based intestinal drug delivery system.
Bioadhesive superporous hydrogel composite (SPHC) particles were developed for an intestinal delivery of metoprolol succinate and characterized for density, porosity, swelling, morphology, and bioadhesion studies. Chitosan and HPMC were used as bioadhesive and release retardant polymers, respectivel...
Antibodies against food antigens in patients with autistic spectrum disorders.
Immune system of some autistic patients could be abnormally triggered by gluten/casein assumption. The prevalence of antibodies to gliadin and milk proteins in autistic children with paired/impaired intestinal permeability and under dietary regimen either regular or restricted is reported. 162 ASDs...
Production of fungal amylases using cheap, readily available agriresidues, for potential application in textile industry.
The study aimed at isolation and screening of fungal amylase producer, optimization of solid state fermentation conditions for maximum amylase production by the best amylase producer, and characterization of the crude amylases, so produced. Aspergillus fumigatus NTCC1222 showed the highest amylase a...
Comparison of extraction methods of chitin from Ganoderma lucidum mushroom obtained in submerged culture.
The chitin was isolated from the Ganoderma lucidum submerged cultures mycelium as potential source of chitin under biotechnological processes. The extraction of chitin was carried out through 5 different assays which involved mainly three phases: pulverization of the mushroom, deproteinization of th...
Evaluation of antioxidant compounds, antioxidant activities, and mineral composition of 13 collected purslane (Portulaca oleracea L.) access...
The methanolic extracts of 13 accessions of purslane were analyzed for their total phenol content (TPC), total flavonoid contents (TFC), and total carotenoid contents (TCC) and antioxidant activity of extracts was screened using FRAP assay and DPPH radical scavenging methods. The TPC, TFC, and TCC r...