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BioMed Research International

Print ISSN
2314-6133
Publisher
Hindawi Publishing Corporation

  1. Genetics of Alzheimer's disease.

    BioMed research international 2013:254954 (2013) PMID 23984328 PMCID PMC3741956

    We review the known genetics of early- and late-onset Alzheimer's disease....
  2. Aorta structural alterations in term neonates: the role of birth and maternal characteristics.

    BioMed research international 2013:459168 (2013) PMID 23984364 PMCID PMC3741912

    To evaluate the influence of selected maternal and neonatal characteristics on aorta walls in term, appropriately grown-for-gestational age newborns. Age, parity, previous abortions, weight, height, body mass index before and after delivery, smoking, and history of hypertension, of diabetes, of card...
  3. Development of bioadhesive chitosan superporous hydrogel composite particles based intestinal drug delivery system.

    BioMed research international 2013:563651 (2013) PMID 23984380 PMCID PMC3747347

    Bioadhesive superporous hydrogel composite (SPHC) particles were developed for an intestinal delivery of metoprolol succinate and characterized for density, porosity, swelling, morphology, and bioadhesion studies. Chitosan and HPMC were used as bioadhesive and release retardant polymers, respectivel...
  4. Antibodies against food antigens in patients with autistic spectrum disorders.

    BioMed research international 2013:729349 (2013) PMID 23984403 PMCID PMC3747333

    Immune system of some autistic patients could be abnormally triggered by gluten/casein assumption. The prevalence of antibodies to gliadin and milk proteins in autistic children with paired/impaired intestinal permeability and under dietary regimen either regular or restricted is reported. 162 ASDs...
  5. Isocitrate dehydrogenase-1 mutations as prognostic biomarker in glioblastoma multiforme patients in West Bohemia.

    BioMed research international 2014:735659 (2014) PMID 24511544 PMCID PMC3910481

    We investigated the prognostic role of IDH1 R132H mutation in GBM patients in West Bohemia. The IDH1 R132H mutation was assessed by the RT-PCR in the tumor samples from 45 GBM patients treated in the Faculty Hospital in Pilsen and was correlated with the progression free and overall survival. The ID...
  6. Formulation and evaluation of fixed-dose combination of bilayer gastroretentive matrix tablet containing atorvastatin as fast-release and at...

    BioMed research international 2014:396106 (2014) PMID 24527446 PMCID PMC3909979

    The objective of the present study was to develop bilayer tablets of atorvastatin and atenolol that are characterized by initial fast-release of atorvastatin in the stomach and comply with the release requirements of sustained-release of atenolol. An amorphous, solvent evaporation inclusion complex...
  7. Oncogenic processes.

    BioMed research international 2014:879013 (2014) PMID 24551854 PMCID PMC3914301

  8. Food-derived bioactive peptides on inflammation and oxidative stress.

    BioMed research international 2014:608979 (2014) PMID 24527452 PMCID PMC3914560

    We summarize the roles of various food-derived bioactive peptides in inflammation and oxidative stress and discuss the potential benefits and limitations of using these compounds against the burden of chronic diseases....
  9. Some in vitro/in vivo chemically-induced experimental models of liver oxidative stress in rats.

    BioMed research international 2014:706302 (2014) PMID 24551852 PMCID PMC3914340

    We discuss further....
  10. The Role of PinX1 in Growth Control of Breast Cancer Cells and Its Potential Molecular Mechanism by mRNA and lncRNA Expression Profiles Scre...

    BioMed research international 2014:978984 (2014) PMID 24672800 PMCID PMC3929369

    We found a lower growth rate, G0/G1 phase arrest, and S phase inhibition in the PinX1 overexpressed breast cancer cells, while a higher growth rate, decreased G0/G1 phase, and increased S phase rate in the PinX1 knocked-down nontumorigenic breast cell. A total of 977 mRNAs and 631 lncRNAs were ident...