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All Organic Chemicals Amides Benzamides

Benzamides 696 articles


  1. The use of roflumilast in COPD: a primary care perspective.

    Primary Care Respiratory Journal 19(4):342 (2010) PMID 21085915

    Therapeutic interventions in chronic obstructive pulmonary disease (COPD) shown to reduce exacerbations include smoking cessation, vaccination and appropriate pharmacological therapy. Long-acting bronchodilators are the cornerstone of COPD pharmacotherapy, whereas inhaled corticoster...
  2. Hypoglycemic neuronal death and cognitive impairment are prevented by poly(ADP-ribose) polymerase inhibitors administered after hypoglycemia...

    Journal of Neuroscience 23(33):10681 (2003) PMID 14627653

    These results suggest that PARP-1 activation is a major factor mediating hypoglycemic neuronal death and that PARP-1 inhibitors can rescue neurons that would otherwise die after severe hypoglycemia....
  3. [Reflux esophagitis].

    Nippon rinsho. Japanese journal of clinical med... 60(8):1559 (2002) PMID 12187751

    There are some factors which influence reflux esophagitis, in our country atrophic gastritis is important for the degree of it especially. Helicobacter pylori(H.P.) infection is popular in aged patients, so atrophic gastritis is also popular in such patients, then the frequency of reflux esophagitis...
  4. Effects of intracolonic opioid receptor agonists on polymodal pelvic nerve afferent fibers in the rat.

    Journal of Neurophysiology 83(2):963 (2000) PMID 10669508

    We studied the effects of intracolonic administration of opioid receptor agonists (ORAs) on responses of pelvic nerve afferent fibers to colorectal distension (CRD) and heat. Single-fiber recordings were made from the decentralized S1 dorsal rootlet in the rat. An approximately 7-cm length of descen...
  5. [Mechanism of the etiology of dyspeptic disorders during the period of primary reaction after exposure to high-dose ionizing radiation].

    Radiatsionnaia Biologiia, Radioekologii 38(6):819 (1998) PMID 9889776

    The experiments with dogs exposed to accelerated electrons at a dose of 100 Gy have confirmed an important role of the central mechanism of early post-radiation dyspepsia which is realized through the excitation of receptors in the mechanism of postradiation gastrointestinal disturbance, alongside b...
  6. Registration of dynamic dopamine D2 receptor images using principal component analysis.

    European Journal of Nuclear Medicine 24(11):1405 (1997) PMID 9371874

    This paper describes a novel technique for registering a dynamic sequence of single-photon emission tomography (SPET) dopamine D2 receptor images, using principal component analysis (PCA). Conventional methods for registering images, such as count difference and correlation coefficient algorithms, f...
  7. Moclobemide effects on prolactin plasma levels in healthy individuals: the hormonal increase induced by a single dose is maintained during a...

    International Clinical Psychopharmacology 12(6):317 (1997) PMID 9547133

    Neuroendocrine challenge studies are frequently used to study the pathophysiology of psychiatric illnesses and the effects of psychotropic drug treatment on brain monoamine function. Moclobemide, a reversible inhibitor of monoamine oxidase, with predominant effects on the A-type of the enzyme, was a...
  8. Assessment of endogenous dopamine release by methylphenidate challenge using iodine-123 iodobenzamide single-photon emission tomography.

    European Journal of Nuclear Medicine 24(6):674 (1997) PMID 9169577

    This double-blind, placebo-controlled study assessed pharmacologically induced endogenous dopamine (DA) release in healthy male volunteers (n=12). Changes in endogenous DA release after injection of the psychostimulant drug methylphenidate were evaluated by single-photon emission tomography (SPET) a...
  9. Central antitussive activity of the NK1 and NK2 tachykinin receptor antagonists, CP-99,994 and SR 48968, in the guinea-pig and cat.

    British Journal of Pharmacology 121(2):165 (1997) PMID 9154323

    We concluded that CP-99,994 and SR 48968 inhibit cough in the guinea-pig and cat by a central site of action. In the cat, the antitussive action of these compounds appears to be solely by a central site....
  10. In vitro pharmacological profile of YM-43611, a novel D2-like receptor antagonist with high affinity and selectivity for dopamine D3 and D4 ...

    British Journal of Pharmacology 117(8):1625 (1996) PMID 8732269 PMCID 1909569

    We investigated some neurochemical properties of a novel benzamide, YM-43611, [(S)-N-(1-benzyl-3-pyrrolidinyl)-5-chloro-4-cyclopropylcarbonylamino+ ++-2- methoxybenzamide] in comparison with putative D2-like receptor antagonists using both rat and human cloned dopamine D2-like receptors in vitro. 2....