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All Cells Blood Cells Leukocytes Leukocytes, Mononuclear Cytokine-Induced Killer Cells

Cytokine-Induced Killer Cells 6 articles


  1. [Preliminary assessment of immune reconstitution after autologous peripheral hematopoietic stem cell transplantation (AHSCT)].

    Ai zheng = Aizheng = Chinese journal of cancer 25(8):1023 (2006) PMID 16965687

    Administration of CIK cells, thymus factor, IL-2 and IFN-alpha after AHSCT could improve the immunologic function of patients, and TH1/TH2 ratio may virtually reflect the immune status of patients. However more information is required to make prognostic assessments of immune reconstruction and the l...
  2. Dendritic cell-activated cytokine-induced killer cells enhance the anti-tumor effect of chemotherapy on non-small cell lung cancer in patien...

    Cytotherapy 11(8):1076 (2009) PMID 19929470

    This study suggests that the role of DC-activated CIK cells in improvement of chemotherapy for malignant tumor treatment is associated with up-regulation of the production of cytokines involved in the anti-tumor effect....
  3. Immunotherapy in high-risk chemotherapy-resistant patients with metastatic solid tumors and hematological malignancies using intentionally m...

    Cancer Immunology, Immunotherapy 59(10):1511 (2010) PMID 20563804

    We present our phase 1 clinical study data in a cohort of 40 high-risk patients with metastatic solid tumors and hematological malignancies. Treatment was accompanied by some malaise and occasional self-limited fever but otherwise well tolerated on an outpatient basis. Transient engraftment of donor...
  4. [Biological characteristics and antitumor activity of CIK cells activated by recombinant human fibronectin for human lung cancer cell lines ...

    Chinese Journal of Lung Cancer 13(4):277 (2010) PMID 20677549

    We separated the mononuclear cells (PBMCs) in 50 mL peripheral blood from 10 healthy persons with density gradient centrifugation in the lymphocyte-separating medium, and the PBMCs were divided into two groups, of which were cultivated by RN-introduced and conventional method separately. Then we est...
  5. Optimized protocols for generation of cord blood-derived cytokine-induced killer/natural killer cells.

    Audio, Transactions of the IRE Professional Gro... 30(9):3493 (2010) PMID 20944128

    The efficacy of various combinations of stem cell factor (SCF), FLT3 ligand, interleukin (IL)-2, IL-7 and IL-15 to induce and expand cord blood-derived cytokine-induced killer (CIK) cells was investigated. There were three treatment groups: group A: SCF combined with IL-2, IL-7 and IL-15; group B: S...
  6. [Effects of human bone marrow mesenchymal stem cells on cytokines secretion from allogeneic dendritic cell activated cytokine-induced killer...

    Xi bao yu fen zi mian yi xue za zhi = Chinese j... 26(10):988 (2010) PMID 20937236

    to study the effect of human bone marrow derived mesenchymal stem cells (hMSCs) on cytokines secretion (IFN-γ, TNF-α, IL-10, IL-6, IL-4 and IL-2) of allogeneic DC-CIK cells (in co-culture of CIK cells with DC), which investigate the mechanism of immunoregulation induced by hMSCs. the hMSCs from bo...