Immune System 4,108 articles
- Antibody-Producing Cells
- Antigen-Presenting Cells
- Bone Marrow
- Enterochromaffin Cells
- Immunological Synapses
The missing sense modality: the immune system.
I argue that it has only taken two millennia to recognize that the immune system has been the hidden sensory modality. The immune system completes the range of operation allowing detection of meaningful entities at all distances, from very near to very far. It also withstands the often implicit crit...
Developmental vitamin D"3 deficiency induces alterations in immune organ morphology and function in adult offspring
We hypothesised that the developmental absence of vitamin D3 may alter thymic development and thus produce associated functional changes in T cells. We have developed a model of developmental vitamin D3 (DVD) deficiency in Sprague-Dawley rats, in which the vitamin D3 deficiency is transient and rest...
Analysis of in vivo dynamics of influenza virus infection in mice using a GFP reporter virus.
We report the generation of a recombinant influenza virus carrying a GFP reporter gene in the NS segment (NS1-GFP virus). Although attenuated when compared with wild-type virus, the NS1-GFP virus replicates efficiently in murine lungs and shows pathogenicity in mice. Using whole-organ imaging and fl...
Autism: an emerging ‘neuroimmune disorder’ in search of therapy
BACKGROUND: Autism spectrum disorders (ASDs) are neurodevelopmental disorders characterized by difficulties in communication and by repetitive and stereotypic behaviors, as well as by social impairment, attention, cognitive, and learning defects. ASDs present in early childhood and their prevalence...
Origins. On the origin of the immune system.
Functional changes induced by long-term stimulation of nicotinic acetylcholine receptors. Foreword.
Early maternal deprivation in rats: a proposed animal model for the study of developmental neuroimmunoendocrine interactions.
We review here these neuroendocrine effects and show new data indicating that the MD procedure induces diverse detrimental effects on the immune system that are already revealed in the short term (PND 13) and persist into adulthood. These long-lasting effects might be related to altered hypothalamus...
Looking ahead in cancer stem cell research.
The gastrointestinal tract (GIT) microbiota plays an important role in host health due to its involvement in nutritional, immunologic and physiological functions. Microbial imbalances have been associated with enhanced risk of specific diseases. This observation has allowed the introduction of micro...
Siglecs as positive and negative regulators of the immune system.
We review recent findings on the signalling properties of the CD33-related siglecs and discuss the emergence of both inhibitory and activating forms of this family. We also discuss how Sn may function as a positive regulator of adaptive immune responses and its emerging role as an induced macrophage...