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Metabolic Clearance Rate 2,055 articles


  1. Diabinese-Dialume: a potential catastrophe.

    Uremia investigation 8(2):135 (1984) PMID 6537686

    We provide recommendations regarding therapy, bedside glucose monitoring, and prevention....
  2. Dietary protein as a risk factor in gentamicin nephrotoxicity.

    Renal Failure 10(3-4):153 (1987) PMID 3504004

    Our findings indicate that conditioning to higher dietary protein prior to gentamicin administration results in less uptake of gentamicin by the kidneys. If rats on HP diets are placed on LP coincident with gentamicin administration, there is a significant improvement in survival. Switching rats fro...
  3. Enzyme-linked immunosorbent assay of carbamoylphosphate synthetase I: plasma enzyme in rat experimental hepatitis and its clearance.

    Enzyme & protein 48(4):213 (1994) PMID 8821709

    We developed a sensitive enzyme-linked immunosorbent assay (ELISA) for measurement of the enzyme in plasma using an antibody against the rat enzyme. In galactosamine-induced rat acute hepatitis, plasma concentration of CPS I that was 1-2 micrograms/ml blood before the treatment, increased up to 125...
  4. Pharmacokinetics of phenytoin in acute adult and child intoxication.

    Journal of Toxicology: Clinical Toxicology 24(6):519 (1986) PMID 3573125

    We suggest that these kinetic parameters for phenytoin probably are independent of age....
  5. Symptomatic hyponatremia: pathophysiology and management.

    Acute care 14-15:270 (1988) PMID 3155033

    We believe that the osmotic difference between the brain cell and the extracellular fluid is the critical parameter in determining therapy. A gradient of 30 mosm/kg or more produces significant shifts of intracellular water and cell damage. Seizure and coma are the neurologic signs associated with a...
  6. Managing rapid metabolizers of antidepressants.

    Depression and Anxiety (Hoboken) 4(6):320 (1996) PMID 9166660

    Depressed patients who rapidly metabolize antidepressants may be common, and may not respond to even high doses of antidepressants if subtherapeutic plasma levels are produced. Rapid metabolizers (RMs) are identifiable if patients are on tricyclic antidepressants (TCAs), and TCA plasma levels (commo...
  7. Plasma levels of tricyclic antidepressants in panic disorder.

    International Journal of Psychiatry in Medicine 13(2):93 (1983) PMID 6642878

    Five patients with panic disorder were placed on low doses of imipramine. All patients had shown dramatic improvement after three weeks of treatment, when plasma levels of imipramine and desipramine were measured. Plasma levels corresponded to the low doses being administered. This result implies th...
  8. Is flunarizine a long-acting oral atypical antipsychotic? A randomized clinical trial versus haloperidol for the treatment of schizophrenia.

    Journal of Clinical Psychiatry 69(10):1572 (2008) PMID 19192440

    Mean doses at endpoint were 29.7 mg/day for flunarizine and 6.4 mg/day for haloperidol. Both groups showed significant symptom improvement during the study, with a reduction of 21% in the flunarizine group and 19% in the haloperidol group in PANSS total scores (p < .05). There were no significant di...
  9. Comparing infant oral glucose clearance with and without a water rinse.

    The Journal of the Indiana Dental Association 82(4):25 (2003) PMID 15354382

    The purpose of this study was to test the hypothesis that a small rinse of water in an infant's mouth immediately following formula consumption would significantly improve oral glucose clearance. Though statistically significant results were not obtained at all time intervals, this study lends valid...
  10. [Kidney retention of urea in sheep on a hypoprotein diet: study by retrograde perfusion of urea in the kidney pelvis].

    Journal of Physiology 83(2):64 (1988) PMID 3251040

    In order to study the role of the renal pelvis on urea sparing in sheep fed low protein diets, the pelvis was perfused through the ureter with 1M and 3M urea solutions. Eight ewes were used: four on a regular diet (total nitrogen 188.7 g.kg-1 dry matter) and the other four on a low protein diet (tot...