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All Nervous System Diseases Neurologic Manifestations Neurogenic Inflammation

Neurogenic Inflammation 36 articles


  1. Orofacial deep and cutaneous tissue inflammation differentially upregulates preprodynorphin mRNA in the trigeminal and paratrigeminal nuclei...

    Molecular Brain Research 67(1):87 (1999) PMID 10101236

    These results indicate that TMJ inflammation resulted in a more intense and widespread increase in PPD mRNA expression when compared to PO inflammation. These changes may contribute to persistent central hyperexcitability and pain associated with temporomandibular disorders. Copyright 1999 Elsevier...
  2. [Neuronal mechanisms of chronic pain]

    Der Orthopäde 33(5):515 (2004) PMID 15045171

    Until recently the paradigms of pain research were predominantly related to acute pain in humans and animals. Some 20 years ago the focus of basic and clinical research was shifted towards the mechanisms of chronic pain. Usually the nociceptors of our joints respond only to overload and lesions and...
  3. Expression of neurotransmitters and neurotrophins in neurogenic inflammation of the rat retina.

    European Journal of Histochemistry 51(4):251 (2007) PMID 18162454

    Antidromic stimulation of the rat trigeminal ganglion triggers the release of substance P (SP) and calcitonin gene-related peptide (CGRP) from sensory nerve terminals of the capsaicin sensitive C-fibers. These pro-inflammatory neuropeptides produce a marked hyperemia in the anterior segment of the e...
  4. Analgesic effect of subcutaneous administration of oxygen-ozone. A blind study in the rat on the modulation of the capsaicin-induced edema.

    Acupuncture and Electro-Therapeutics Research 23(3-4):171 (1998) PMID 10193702

    The Authors have explored a new complementary approach, employed in the last 40 years for, among other uses, medical purposes: oxygen-ozone therapy. Anecdotal works have highlighted interesting results obtained in disk herniation with infiltration of paravertebral muscles with oxygen-ozone. To verif...
  5. Interleukin-6 and nerve growth factor levels in peripheral nerve and brainstem after trigeminal nerve injury in the rat.

    Archives of Oral Biology 46(7):633 (2001) PMID 11369318

    We demonstrate bilateral changes in interleukin-6 (IL-6) and nerve growth factor (nerve growth factor) levels following unilateral infraorbital nerve (infraorbital nerve) constriction. infraorbital nerve constriction resulted in an initial period of decreased mechanical sensitivity (1 and 3 days), f...
  6. Periapical inflammatory responses and their modulation.

    Critical Reviews in Oral Biology & Medicine 9(4):498 (1998) PMID 9825224

    Periapical inflammatory responses occur as a consequence of bacterial infection of the dental pulp, as a result of caries, trauma, or iatrogenic insult. Periapical inflammation stimulates the formation of granulomas and cysts, with the destruction of bone. These inflammatory responses are complex an...
  7. Substance P expression is elevated in inflamed human periradicular tissue.

    Journal of Endodontics 30(5):329 (2004) PMID 15107644

    We observed the presence of neutrophils expressing substance P without concurrent clinical symptoms of acute inflammation. Our results are consistent with the hypothesis that substance P may be released from neutrophils in the inflamed region, and thus, substance P may modulate clinical inflammatory...
  8. Central nervous system plasticity and persistent pain.

    Journal of orofacial pain 13(3):155 (1999) PMID 10823030

    Nerve signals arising from sites of tissue or nerve injury lead to long-term changes in the central nervous system and contribute to hyperalgesia and the amplification and persistence of pain. These nociceptor activity-induced changes are referred to as central sensitization. Central...
  9. Neurogenic inflammation of the ocular surface.

    Current Opinion in Allergy and Clinical Immunology 10(5):498 (2010) PMID 20706114

    We present the most recent advances in the understanding of the roles played by nerve endings and neuropeptides in local inflammatory processes of the ocular surface, in order to better clarify their function in physiologic and pathologic conditions and to open new research, diagnostic, and therapeu...
  10. Neutralization of endogenous NGF prevents the sensitization of nociceptors supplying inflamed skin.

    European Journal of Neuroscience 11(5):1698 (1999) PMID 10215923

    We asked whether NGF contributes to sensitization of primary afferent nociceptors, which are an important component of pain and hyperalgesia in inflamed tissue. An in vitro skin nerve preparation of the rat was used to directly record the receptive properties of thin myelinated (Adelta) and unmyelin...