Proteins 88,814 articles
- Algal Proteins
- Amphibian Proteins
- Antifreeze Proteins
- Archaeal Proteins
- Armadillo Domain Proteins
- Avian Proteins
- Bacterial Proteins
- Blood Proteins
- Carrier Proteins
- Cell Cycle Proteins
- Cerebrospinal Fluid Proteins
- Contractile Proteins
- Cytoskeletal Proteins
- Dental Enamel Proteins
- Dietary Proteins
- DNA-Binding Proteins
- Dynein ATPase
- Egg Proteins
- Epididymal Secretory Proteins
- Eye Proteins
- Fanconi Anemia Complementation Group Proteins
- Fetal Proteins
- Fish Proteins
- Fungal Proteins
- GTP-Binding Protein Regulators
- Heat-Shock Proteins
- Helminth Proteins
- Immediate-Early Proteins
- Immobilized Proteins
- Insect Proteins
- Intercellular Signaling Peptides and Proteins
- Intracellular Signaling Peptides and Proteins
- Iron-Regulatory Proteins
- LDL-Receptor Related Proteins
- Luminescent Proteins
- Membrane Proteins
- Mitochondrial Proteins
- Molecular Chaperones
- Mutant Proteins
- Neoplasm Proteins
- Nerve Tissue Proteins
- Proteinase Inhibitory Proteins, Secretory
- Nuclear Proteins
- Oxidative Phosphorylation Coupling Factors
- Photoreceptors, Microbial
- Photosynthetic Reaction Center Complex Proteins
- Plant Proteins
- Pregnancy Proteins
- Protein Hydrolysates
- Protein Isoforms
- Protein Precursors
- Protein Subunits
- Protozoan Proteins
- Pulmonary Surfactant-Associated Proteins
- Receptors, Cytoplasmic and Nuclear
- Receptors, Drug
- Recombinant Proteins
- Reptilian Proteins
- Ribosomal Proteins
- Salivary Proteins and Peptides
- Selenium-Binding Proteins
- Seminal Plasma Proteins
- Silver Proteins
- Tissue Inhibitor of Metalloproteinases
- Transcription Factors
- Viral Proteins
Unraveling lipid/protein interaction in model lipid bilayers by Atomic Force Microscopy.
We will review the technical aspects inherent to and the main results obtained by AFM in the study of protein partitioning in lipid domains concentrating in particular on GPI-anchored proteins, lipidated proteins, and transmembrane proteins. Whenever possible, we will also discuss the functional con...
Handling of solid brain tumor tissue for protein analysis.
We suggest handling the brain tumor tissue sterilely and coldly (on ice) for as short time as possible prior to processing, but for no more than 8 h. This simple protocol results in apparently intact morphology, immunoreactivity, protein integrity, and protein phosphorylation with the criteria we ap...
A partial set covering model for protein mixture identification using mass spectrometry data.
We extend this technology to protein mixture identification. First, we formulate the problem of protein mixture identification as a Partial Set Covering (PSC) problem. Then, we present several algorithms that can solve the PSC problem efficiently. Finally, we extend the partial set covering model to...
Celebrating structural biology.
Prediction of the disulphide bonding state of cysteines in proteins using conditional random fields.
We developed a novel method based on Conditional Random Fields (CRFs) to predict the disulphide bonding state from protein primary sequence, predicted secondary structures and predicted relative solvent accessibilities (all-state information). Our experiments obtain 84% accuracy, 88% precision and 9...
Physicochemical characterization of protein-loaded pectin-chitosan nanoparticles prepared by polyelectrolyte complexation.
Recent advances in nanotechnology applied to proteins are directed towards safer and simpler methods of preparation, using naturally occurring polymers such as alginate, pectin and chitosan. In this study, pectin-chitosan nanoparticles (NPs) were designed by the mild process of polyelectrolyte compl...
Differential expression of liver and kidney proteins in a mouse model for primary hyperoxaluria type I.
We have developed an Agxt knockout (AgxtKO) mouse that reproduces some key features of primary hyperoxaluria type I. To improve our understanding of the metabolic adjustments subsequent to AGXT deficiency, we performed a proteomic analysis of the changes in expression levels of various subcellular f...
Naphthyl methacrylate-phenylene diacrylate-based monolithic column for reversed-phase capillary electrochromatography via hydrophobic and π ...
A neutral naphthyl methacrylate-phenylene diacrylate-based monolith (NPM) was introduced for RP-CEC of various neutral and charged solute probes via hydrophobic and π interactions. The NPM column was prepared by the in situ polymerization of naphthyl methacrylate as the functional m...
[Study on natural products for drug development].
We paid an attention to inhibitors against three enzymes, ubiquitin-activating enzyme (E1), ubiquitin-conjugating enzyme (E2), and ubiquitin-protein ligase (E3), which are required for polyubiquitination of proteins and prerequisite to proteasome-mediated protein degradation. We succeeded in isolati...
Anti-oxidative stress and beyond: multiple functions of the protein glutathionylation.
Glutathionylation, covalently attaching glutathione(s) to cysteine residue(s) of a protein, has attracted great attention in recent years. The importance of glutathionylation was initially recognized for its role in protecting proteins from irreversible oxidation; however, more studi...