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Amino Acids, Peptides, and Proteins (3)


Articles on Amino Acids, Peptides, and Proteins

  1. IGF1 mRNA Splicing Variants in Liaoning Cashmere Goat: Identification, Characterization, and Transcriptional Patterns in Skin and Visceral O...

    Anim Biotechnol 24(2):81-93 (2013) PMID 23534956

    We isolated and characterized three kinds of IGF1 mRNA splicing variants from the liver of Liaoning Cashmere goat, and the expression characterization of the IGF1 mRNA splicing variants were investigated in skin and other tissues of Liaoning cashmere goat. The sequencing results indicated that the c...
  2. Protein encapsulation in and release from monodisperse double-wall polymer microspheres.

    J Pharm Sci (2013) PMID 23529836

    Biodegradable polymer double-wall microspheres (DWMS) are promising vehicles for macromolecular therapeutics such as proteins and peptides. Using precision particle fabrication (PPF) technology, uniform DWMS with outer diameter approximately 55 μm were fabricated comprising poly(lac...
  3. PNA-peptide Assembly in a 3D DNA Nanocage at Room Temperature.

    J Am Chem Soc (2013) PMID 23521013

    We demonstrate a new approach to rationally design 3D nucleic acid-amino acid complexes using Peptide Nucleic Acid (PNA) to assemble peptides inside a 3D DNA nanocage. The PNA-peptides were found to bind to the preassembled DNA nanocage in 5-10 minutes at room temperature and assembly could be perfo...
  4. Proteolytic elimination of N-myristoyl modifications by the Shigella virulence factor IpaJ.

    Nature (2013) PMID 23535599

    We describe an irreversible mechanism of protein demyristoylation catalysed by invasion plasmid antigen J (IpaJ), a previously uncharacterized Shigella flexneri type III effector protein with cysteine protease activity. A yeast genetic screen for IpaJ substrates identified ADP-ribosylation factor (A...
  5. Identification of a Protein Interacting with the Spore Wall Protein SWP26 of Nosema bombycis in a Cultured BmN Cell Line of Silkworm.

    Infect Genet Evol (2013) PMID 23542093

    Nosema bombycis is a silkworm parasite that causes severe economic damage to sericulture worldwide. It is the first microsporidia to be described in the literature, and to date, very little molecular information is available regarding microsporidian physiology and their relationships...
  6. Mixed Ligand Cu(2+) Complexes of a Model Therapeutic with Alzheimer's Amyloid-β Peptide and Monoamine Neurotransmitters.

    Inorg Chem (2013) PMID 23537393

    We show that the homologous ligand 2-[(dimethylamino)methyl]-8-hydroxyquinoline (HL) forms a CuL complex with a conditional (apparent) dissociation constant of 0.33 nM at pH 6.9 and is capable of forming ternary Cu(2+) complexes with neurotransmitters including histamine (HA), glutamic acid (Glu), a...
  7. Anti-hyperglycaemic globulins from selected Cucurbitaceae seeds used as antidiabetic medicinal plants in Africa.

    BMC Complement Altern Med 13(1):63 (2013) PMID 23506532

    These findings showed that the selected Cucurbitaceae seeds contained globulins with significant anti-hyperglycaemic activity. It is therefore highly encouraged to pursue investigations towards development of peptide-drugs and/or phytomedicines from these bioactive proteins which could be used as af...
  8. Comparison of periplasmic and intracellular expression of Arabidopsis thionin proproteins in E. coli.

    Biotechnol Lett (2013) PMID 23515894

    We tested the expression of all four Arabidopsis proproteins as fusion proteins. Periplasmic expression as fusion with maltose binding protein was not successful but cytoplasmic expression as His-tagged TRX fusion proteins with a TEV recognition sequence resulted in proteins of correct size. Use of...
  9. Sequence-specific determination of protein and peptide concentrations by absorbance at 205 nm.

    Protein Sci (2013) PMID 23526461

    We propose and validate a method for predicting the molar absorptivity of a protein or peptide at 205 nm directly from its amino acid sequence, allowing one to accurately determine concentrations of proteins that do not contain tyrosine or tryptophan residues. This method is simple to implement, req...
  10. Fatty acid binding protein 3 (fabp3) is associated with insulin, lipids and cardiovascular phenotypes of the metabolic syndrome through epig...

    BMC Med Genomics 6(1):9 (2013) PMID 23510163

    Our findings suggest that DNA methylation of FABP3 strongly influences MetS, and this may have important implications for cardiovascular disease....