Find your PDFs fast.
Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Peptides (33):
- Oligopeptides
- Intracellular Signaling Peptides and Proteins
- Fibrinopeptide B
- Fibrinopeptide A
- Phosphopeptides
- Peptide Hormones
- Neuropeptides
- Glycopeptides
- Peptides, Cyclic
- Opioid Peptides
- Diazepam Binding Inhibitor
- Proteinase Inhibitory Proteins, Secretory
- Peptide Fragments
- Cholecystokinin
- Charybdotoxin
- Myocardial Depressant Factor
- Edeine
- Intercellular Signaling Peptides and Proteins
- Polylysine
- Peptoids
- Salivary Proteins and Peptides
- Polyglutamic Acid
- Distamycins
- Polygeline
- Lipopeptides
- Disintegrins
- Aptamers, Peptide
- Peptaibols
- Tyrothricin
- Tissue Polypeptide Antigen
- Protein Sorting Signals
- Peptide Library
- Antimicrobial Cationic Peptides
Recent article
Peptides
Organic Letters (12)23 2010
Abstract
The first total synthesis of symplostatin 4, a marine cyanobacterium-derived natural product, is described. Notable features of the route include the efficient preparation of three key fragments and final assembly to the natural product via sequential imide and amide couplings. Sympl...
|
PMID: 21049908
PDF is available here.
PDF is available here.
| < More recent | Older article > |
Abstract
We sought to develop an active method to increase the circulation half-life of proteins by binding to erythrocytes in blood. Screening a naive phage-displayed peptide library against whole mouse erythrocytes yielded a 12 amino acid peptide (ERY1) that binds the erythrocyte surface with high specific...
|
PMID: 20831257
PDF is available here.
PDF is available here.
Abstract
We report that Treg promotes such neuroprotection by an even broader range of mechanisms than previously seen including inhibition of virus release, killing infected MP, and inducing phenotypic cell switches. Changes in individual Treg-induced macrophage proteins were quantified by iTRAQ labeling fo...
|
PMID: 20954747
PDF is available here.
PDF is available here.
Abstract
The human Ether-à-go-go Related Gene (hERG) potassium channel mediates the rapid delayed rectifier current (IKr) in the cardiac action potential. Mutations in the 135 amino acid residue N-terminal domain (NTD) cause channel dysfunction or mis-translocation. To study the structure of NTD, it was ove...
|
PMID: 21055387
PDF is available here.
PDF is available here.
Abstract
We have designed several peptidomimetics to inhibit HER2-mediated signaling for cell growth. One of the compounds (HERP5, Arg-beta Naph-Phe) exhibited antiproliferative activity with IC(50) values in the micromolar-to-nanomolar range in breast cancer cell lines. Binding of fluorescently labeled HERP...
|
PMID: 20919746
PDF is available here.
PDF is available here.
Abstract
The structural and thermodynamic characters of alpha-syn12 peptide in aqueous solution at different pH and temperatures have been investigated through temperature replica exchange molecular dynamics (T-REMD) simulations with GROMOS 43A1 force field. The two independent T-REMD simulations were comple...
|
PMID: 20919750
PDF is available here.
PDF is available here.
British Journal of Nutrition (104)11 2010
Abstract
We sought to determine whether postcaesarean treatment with whey peptides (WP) affects the healing of skin and uterine incision in rats during puerperium. Forty-eight rats were randomly divided into two groups. After a caesarean section, twenty-four rats were intragastrically administered WP, while...
|
PMID: 20691127
PDF is available here.
PDF is available here.
Abstract
The crude extracts from three species of sea anemones (Cryptodendrum adhaesivum, Heterodactyla hemprichii and Thalassianthus aster) belonging to the family Thalassianthidae exhibited potent lethality to freshwater crabs (Potamon dehaani). Regardless of the species, high and low molecular weight toxi...
|
PMID: 20817118
PDF is available here.
PDF is available here.
Abstract
Angiogenin is one of the more potent angiogenic factors known, whose activity may be affected by the presence of copper ions. Copper(II) complexes with the peptides encompassing the putative endothelial cell binding domain of angiogenin, Ac-KNGNPHREN-NH(2) and Ac-PHREN-NH(2), have been characterized...
|
PMID: 20941439
PDF is available here.
PDF is available here.
Abstract
We identified the effects of mutation on the structure and dynamics of the amyloidogenic peptide apoC-II(60-70), in monomeric and oligomeric states. Methionine (Met60) substitutions to hydrophilic Gln, hydrophobic Val, and methionine sulfoxide residues were investigated and the results compared with...
|
PMID: 20938536
PDF is available here.
PDF is available here.
Oral Oncology (46)12 2010
Abstract
Our study successfully used cell-penetrating peptides to conjugate near-infrared quantum dots for the first time and labeled oral squamous carcinoma cells with quantum dot conjugates by endocytosis for visual in vivo imaging. Because of the strong penetration power to tissues, near-infrared quantum...
|
PMID: 21051276
PDF is available here.
PDF is available here.
Abstract
Acta Biomaterialia (6)12 2010
Abstract
We have used peptide motifs that have been selected to bind to gold, platinum, glass and titanium to modify surfaces with poly(ethylene glycol) anti-fouling polymer and the integrin-binding RGD sequence. The peptides have several advantages over conventional molecular immobilization techniques; they...
|
PMID: 20601249
PDF is available here.
PDF is available here.
Nature Methods (7)12 2010
Abstract
We used an array of self-assembled monolayers to identify peptide surfaces that sustain pluripotent stem cell self-renewal. The effective substrates displayed heparin-binding peptides, which can interact with cell-surface glycosaminoglycans and could be used with a defined medium to culture hES cell...
|
PMID: 21076418
PDF is available here.
PDF is available here.
AAPS Journal (12)4 2010
Abstract
The proteome and peptidome are defined as the set of proteins and peptides present in a tissue or other biological sample. In most proteomic studies, only abundant proteins are detected and, although these are important molecules, they are often well-studied structural proteins. A nu...
|
PMID: 20848247
PDF is available here.
PDF is available here.
Cancer Biology & Therapy (10)11 2010
Abstract
We identified CSCs in primary GBC and in the cell line GBC-SD using the cell surface markers CD44 and CD133. The percentages of CD44+CD133+ cells were 1.76-3.05% in primary tumors and 40.29% in GBC-SD cells. These cells showed stem cell properties, including self-renewal, differentiation potential,...
|
PMID: 20948317
PDF is available here.
PDF is available here.
Giornale italiano di cardiologia (2006) (11)12 Suppl 2 2010
Abstract
We review the data from clinical trials that have assessed the mechanism of action, the efficacy, and safety of exenatide and liraglutide, two analogues already available for therapy. The data of these trials showed that exenatide and liraglutide induced an improvement in glycemic control comparable...
|
PMID: 21361051
PDF is available here.
PDF is available here.
EMBO Journal (29)23 2010
Abstract
We found that, in the rate-limiting intermediate of a chaperonin reaction, the unfolded polypeptide in the cage partly protrudes through a narrow space near the GroEL/GroES interface. Then, the entire polypeptide is released either into the cage or to the outside medium. The former adopts a native s...
|
PMID: 20959808
PDF is available here.
PDF is available here.
Abstract
We used a novel biosensor-based surface plasmon resonance (SPR) technique for estimation of circulating COX-2 levels in 76 patients with oral cancer and 43 normal individuals. Antitumor activities of five COX-2 inhibitory peptides were evaluated using propidium iodide labeling and flow cytometry, al...
|
PMID: 20213098
PDF is available here.
PDF is available here.
Abstract
We explore the compatibility of phosphopeptide synthesis and glycopeptide synthesis with thioester production through N→S acyl transfer....
|
PMID: 20835458
PDF is available here.
PDF is available here.
The inhibitor profiling of the caspase family of proteases using substrate-derived peptide glyoxals.
Abstract
A series of substrate-based α-keto-β-aldehyde (glyoxal) sequences have been synthesised and evaluated as inhibitors of the caspase family of cysteine proteases. A number of potent inhibitor sequences have been identified. For example, a palmitic acid containing sequence pal-Tyr-Val-Ala-Asp-glyoxal...
|
PMID: 20955686
PDF is available here.
PDF is available here.
Chemical Communications (46)42 2010
Abstract
An efficient tandem reaction system was developed, in which primary alcohols were used for the oxidation to the corresponding aldehydes followed by an asymmetric α-oxyamination with a resin-supported peptide catalyst.
|
PMID: 20859596
PDF is available here.
PDF is available here.
Brain research (1360) 2010
Abstract
We have shown for the first time the neuroprotective efficacy of full-length and truncated AP-1 inhibitory peptides in kainic acid and glutamate neuronal excitotoxicity models. The identification of therapeutic targets, such as the AP-1 complex, is an important step for the development of pharmaceut...
|
PMID: 20833150
PDF is available here.
PDF is available here.
Abstract
RNA editing by adenosine deamination is a form of epigenetic control of gene expression wherein the ADAR enzymes convert adenosine to inosine in RNA often changing the meaning of codons. The pre-mRNA for the 2c subtype of serotonin receptor (5-HT2cR) is shown here to support small molecule binding n...
|
PMID: 20820662
PDF is available here.
PDF is available here.
Abstract
We have shown that the presence of 3-nitrotyrosine within a peptide sequence severely depletes the peptide backbone fragments typically observed following electron capture dissociation (ECD) mass spectrometry. Instead, ECD of nitrated peptides is characterised by abundant losses of small neutrals (h...
|
PMID: 20830387
PDF is available here.
PDF is available here.