Find your PDFs fast.
Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Bacterial Outer Membrane Proteins (3):
Recent article
Bacterial Outer Membrane Proteins
Chemmedchem (6)8 2011
Abstract
We previously screened a library of analogues based on the ubiquitous PTP substrate para-nitrophenylphosphate (pNPP) and found that incorporation of a 3-phenyl substituent to give 6-nitro-[1,1'-biphenyl]-3-yldihydrogen phosphate (1) enhanced affinity. Herein we report the conversion of 1 from a subs...
|
PMID: 21671403
PDF is available here.
PDF is available here.
| < More recent | Older article > |
Proteomics (11)16 2011
Abstract
Pseudomonas aeruginosa, an opportunistic human bacterial pathogen, constitutively secretes outer membrane vesicles (OMVs) into the extracellular milieu. Although recent progress has revealed that OMVs are essential for pathogenesis of P. aeruginosa, their proteins have not been compr...
|
PMID: 21751344
PDF is available here.
PDF is available here.
Abstract
We developed a simple, safe, and rapid method to prepare highly purified outer membrane (OM) fragments from these pathogens. Shotgun proteomic analyses of OMs by trypsin shaving and mass spectrometry identified >155 proteins, the majority of which are clearly outer membrane proteins (OMPs). These in...
|
PMID: 21391724
PDF is available here.
PDF is available here.
Abstract
We assessed the protective capacity of recombinant LipL32, the six carboxy-terminal unique Ig-like repeat domains of LigA (LigANI) and a LipL32-LigANI fusion protein in hamsters against infection with Leptospira interrogans serovar Manilae. Despite all of the proteins eliciting antibody responses, n...
|
PMID: 21396409
PDF is available here.
PDF is available here.
Abstract
We assessed the protective capacity of recombinant LipL32, the six carboxy-terminal unique Ig-like repeat domains of LigA (LigANI) and a LipL32-LigANI fusion protein in hamsters against infection with Leptospira interrogans serovar Manilae. Despite all of the proteins eliciting antibody responses, n...
|
PMID: 21396409
PDF is available here.
PDF is available here.
Abstract
We evaluated the potential of Brucella abortus 19 kDa outer membrane protein (U-Omp19) as an edible subunit vaccine against brucellosis. We investigated the protective immune response elicited against oral B. abortus infection after vaccination of mice with leaves from transgenic plants expressing U...
|
PMID: 21264260
PDF is available here.
PDF is available here.
Abstract
We developed a Galleria mellonella larvae (wax worm) model of invasive GAS infection and used it to compare the virulence of serotype M3 GAS strains. We found that GAS causes severe tissue damage and kills wax worms in a dose-dependent manner. The virulence of genetically distinct GAS strains wa...
|
PMID: 21258213
PDF is available here.
PDF is available here.
Gut Microbes (2)1 2011
Abstract
We recently described modulation in expression of BabA and related outer membrane proteins that occurs during colonization of experimental animals. Here we put these findings into a broader context, and speculate on their implications for the host-pathogen relationship.
© 2011 Lande...
|
PMID: 21637017
PDF is available here.
PDF is available here.
Trends in Microbiology (19)1 2011
Abstract
We review a selection of recent structural studies which have major ramifications for our understanding of the passage of macromolecules across the outer membrane.
Copyright © 2010 Elsevier Ltd. All rights reserved....
|
PMID: 21130656
PDF is available here.
PDF is available here.
Abstract
Harpin protein induces disease resistance in diverse plant species. Transcriptome study of tomato (Solanum lycopersicum) genome indicated that harpin activated cellular events of transcription regulation, signaling transduction, stress response, membrane transporting, photosynthesis and cell wall bi...
|
PMID: 20951117
PDF is available here.
PDF is available here.
Abstract
We profiled the outer membrane proteome of growing and starving cells using two strategies. First, outer membrane proteins were enriched by biotinylation of intact cells using the reagent NHS (N-hydroxysuccinimide)-PEO(12) (polyethylene oxide)-biotin with subsequent membrane solubilization and affin...
|
PMID: 20687614
PDF is available here.
PDF is available here.
Abstract
We showed the immunogenicity and protective efficacy of five pertactin recombinants against Bordetella bronchiseptica (Bb) challenge.
The complete coding sequence (2040 bp) of the prn gene (PRN) and its fragments,5'-terminal 1173 bp fragment (PN),3'-terminal 867 bp fragment (PC), two copies of regio...
|
PMID: 21090265
PDF is available here.
PDF is available here.
Proteomics (10)17 2010
Abstract
We optimized a proteolytic shaving approach to identify those surface-exposed protein domains - the surfacome - of S. aureus that are accessible to extracellular bio-macromolecules, for example in the host milieu. Subsequently, this approach was applied to define the surfacomes of four strains with...
|
PMID: 20662103
PDF is available here.
PDF is available here.
Abstract
Avian pathogenic Escherichia coli (APEC) is an important respiratory pathogen of poultry. A variety of virulence-associated genes and serogroups are associated with avian colibacillosis caused by APEC strains. One hundred forty-eight E. coli isolates recovered from diagnosed cases of...
|
PMID: 20618074
PDF is available here.
PDF is available here.
Proteomics (10)17 2010
Abstract
We have used iTRAQ proteomics to identify and quantify alterations in global protein expression of T. forsythia during growth in a biofilm. This is the first proteomic study concentrating on biofilm growth in this key periodontal pathogen, and this study has identified several changes in protein exp...
|
PMID: 20806225
PDF is available here.
PDF is available here.
Abstract
Outer membrane proteins of Pasteurella (P.) multocida have been known to be protective immunogens. Pasteurella lipoprotein E (PlpE) has been reported to be an important cross reactive outer membrane protein in P. multocida. The gene encoding the PlpE of P. multocida serotypes A: 3, B: 2 and D: 1 was...
|
PMID: 20706030
PDF is available here.
PDF is available here.
Abstract
We investigated 37 ethylene-inducible Arabidopsis transcription factor genes for their effects on the activation of ethylene signalling and insect defence. Twenty-eight of the 37 genes responded to both ethylene and HrpN Ea, and showed either increased or inhibited transcription, while 18 genes show...
|
PMID: 20826953
PDF is available here.
PDF is available here.
Archives de Pédiatrie (17)9 2010
Abstract
We report on a case of Streptococcus pyogenes invasive disease with toxic shock syndrome due to an M1 strain producing SpeA and SmeZ superantigenic toxins. Post-streptococcal sequelae included several episodes of reactive arthritis and orchitis whose outcome was favorable with corticosteroid therapy...
|
PMID: 20709506
PDF is available here.
PDF is available here.
Infection and Immunity (78)9 2010
Abstract
Pseudomonas aeruginosa is a prevalent opportunistic human pathogen that, like other Gram-negative pathogens, secretes outer membrane vesicles. Vesicles are complex entities composed of a subset of envelope lipid and protein components that have been observed to interact with and be internalized by h...
|
PMID: 20605984
PDF is available here.
PDF is available here.
Infection and Immunity (78)9 2010
Abstract
We constructed an unmarked, in-frame H. ducreyi cpxA deletion mutant, 35000HPDeltacpxA. In human inoculation experiments, 35000HPDeltacpxA formed papules at a rate and size that were significantly less than its parent and was unable to form pustules compared to the parent. CpxA usually has kinase an...
|
PMID: 20605985
PDF is available here.
PDF is available here.
Abstract
Outer membrane protein A (OmpA) of enterohaemorrhagic Escherichia coli (EHEC) plays multiple roles in bacterial physiology and pathogenesis, such as mediation of bacterial conjunction, maintenance of cell shape, induction of adhesion of EHEC to host cells etc. Better understanding of the functions o...
|
PMID: 20693671
PDF is available here.
PDF is available here.
Abstract
We developed an in vivo method to detect the orientation of outer membrane cytochromes via analysis of electron transfer reactions between these enzymes and riboflavin....
|
PMID: 20451567
PDF is available here.
PDF is available here.
Journal of Medical Microbiology (59)Pt 8 2010
Abstract
Abstract
FEMS Microbiology Letters (309)1 2010
Abstract
BmpA is an immunodominant protein of Borrelia burgdorferi as well as an arthritogenic factor. Rabbit antirecombinant BmpA (rBmpA) antibodies were raised, characterized by assaying their cross reactivity with rBmpB, rBmpC and rBmpD, and then rendered monospecific by absorption with rB...
|
PMID: 20546313
PDF is available here.
PDF is available here.
Genetika (Moskva) (46)8 2010
Abstract
Using cosmid vector, a gene library of German cockroach Blattella germanica was constructed. From this library, clones containing full-length copies of two subfamilies of R1 retroposons were selected. Retroposons R1 of German cockroach belonging to different subfamilies were shown to be different in...
|
PMID: 20873200
PDF is available here.
PDF is available here.
Infection and Immunity (78)8 2010
Abstract
The YopM protein of Yersinia sp. is a type III secreted effector that is required for virulence in murine models of infection. YopM has previously been shown to contain leucine-rich repeats (LRRs) and to interact with two host kinases, RSK1 and PRK2, although the consequence of these interactions is...
|
PMID: 20515922
PDF is available here.
PDF is available here.
Infection and Immunity (78)8 2010
Abstract
Yersinia pestis, the causative agent of plague, evades host immune responses and rapidly causes disease. The Y. pestis adhesin Ail mediates host cell binding and is critical for Yop delivery. To identify the Ail receptor(s), Ail was purified following overexpression in Escherichia coli. Ail bound sp...
|
PMID: 20498264
PDF is available here.
PDF is available here.
Nippon Saikingaku Zasshi (65)2-4 2010
Abstract
Abstract
Borrelia burdorferi genotype in the northeastern United States is associated with Lyme borreliosis severity. Analysis of DNA sequences of the outer surface protein C gene and rrs-rrlA intergenic spacer from extracts of Ixodes spp. ticks in 3 US regions showed linkage disequilibrium between the 2 loc...
|
PMID: 20587192
PDF is available here.
PDF is available here.
Cellular Microbiology (12)7 2010
Abstract
We found that YopE also inhibited reactive oxygen species (ROS) production and inactivated Rac2. How YopE distinguishes among its targets and which specific targets are critical for Yersinia survival in different tissues are unknown. A screen identifying YopE mutants in Yersinia pseudotuberculosis t...
|
PMID: 20148901
PDF is available here.
PDF is available here.
Cellular Microbiology (12)7 2010
Abstract
We found that YopE also inhibited reactive oxygen species (ROS) production and inactivated Rac2. How YopE distinguishes among its targets and which specific targets are critical for Yersinia survival in different tissues are unknown. A screen identifying YopE mutants in Yersinia pseudotuberculosis t...
|
PMID: 20148901
PDF is available here.
PDF is available here.
Cellular Microbiology (12)7 2010
Abstract
We found that YopE also inhibited reactive oxygen species (ROS) production and inactivated Rac2. How YopE distinguishes among its targets and which specific targets are critical for Yersinia survival in different tissues are unknown. A screen identifying YopE mutants in Yersinia pseudotuberculosis t...
|
PMID: 20148901
PDF is available here.
PDF is available here.
Cellular Microbiology (12)7 2010
Abstract
We found that YopE also inhibited reactive oxygen species (ROS) production and inactivated Rac2. How YopE distinguishes among its targets and which specific targets are critical for Yersinia survival in different tissues are unknown. A screen identifying YopE mutants in Yersinia pseudotuberculosis t...
|
PMID: 20148901
PDF is available here.
PDF is available here.
Cellular Microbiology (12)7 2010
Abstract
We found that YopE also inhibited reactive oxygen species (ROS) production and inactivated Rac2. How YopE distinguishes among its targets and which specific targets are critical for Yersinia survival in different tissues are unknown. A screen identifying YopE mutants in Yersinia pseudotuberculosis t...
|
PMID: 20148901
PDF is available here.
PDF is available here.
Cellular Microbiology (12)7 2010
Abstract
We found that YopE also inhibited reactive oxygen species (ROS) production and inactivated Rac2. How YopE distinguishes among its targets and which specific targets are critical for Yersinia survival in different tissues are unknown. A screen identifying YopE mutants in Yersinia pseudotuberculosis t...
|
PMID: 20148901
PDF is available here.
PDF is available here.
Cellular Microbiology (12)7 2010
Abstract
We found that YopE also inhibited reactive oxygen species (ROS) production and inactivated Rac2. How YopE distinguishes among its targets and which specific targets are critical for Yersinia survival in different tissues are unknown. A screen identifying YopE mutants in Yersinia pseudotuberculosis t...
|
PMID: 20148901
PDF is available here.
PDF is available here.
Cellular Microbiology (12)7 2010
Abstract
We found that YopE also inhibited reactive oxygen species (ROS) production and inactivated Rac2. How YopE distinguishes among its targets and which specific targets are critical for Yersinia survival in different tissues are unknown. A screen identifying YopE mutants in Yersinia pseudotuberculosis t...
|
PMID: 20148901
PDF is available here.
PDF is available here.
Cellular Microbiology (12)7 2010
Abstract
We found that YopE also inhibited reactive oxygen species (ROS) production and inactivated Rac2. How YopE distinguishes among its targets and which specific targets are critical for Yersinia survival in different tissues are unknown. A screen identifying YopE mutants in Yersinia pseudotuberculosis t...
|
PMID: 20148901
PDF is available here.
PDF is available here.
Cellular Microbiology (12)7 2010
Abstract
We found that YopE also inhibited reactive oxygen species (ROS) production and inactivated Rac2. How YopE distinguishes among its targets and which specific targets are critical for Yersinia survival in different tissues are unknown. A screen identifying YopE mutants in Yersinia pseudotuberculosis t...
|
PMID: 20148901
PDF is available here.
PDF is available here.
Cellular Microbiology (12)7 2010
Abstract
We found that YopE also inhibited reactive oxygen species (ROS) production and inactivated Rac2. How YopE distinguishes among its targets and which specific targets are critical for Yersinia survival in different tissues are unknown. A screen identifying YopE mutants in Yersinia pseudotuberculosis t...
|
PMID: 20148901
PDF is available here.
PDF is available here.
Cellular Microbiology (12)7 2010
Abstract
We found that YopE also inhibited reactive oxygen species (ROS) production and inactivated Rac2. How YopE distinguishes among its targets and which specific targets are critical for Yersinia survival in different tissues are unknown. A screen identifying YopE mutants in Yersinia pseudotuberculosis t...
|
PMID: 20148901
PDF is available here.
PDF is available here.
Cellular Microbiology (12)7 2010
Abstract
We found that YopE also inhibited reactive oxygen species (ROS) production and inactivated Rac2. How YopE distinguishes among its targets and which specific targets are critical for Yersinia survival in different tissues are unknown. A screen identifying YopE mutants in Yersinia pseudotuberculosis t...
|
PMID: 20148901
PDF is available here.
PDF is available here.
Cellular Microbiology (12)7 2010
Abstract
We found that YopE also inhibited reactive oxygen species (ROS) production and inactivated Rac2. How YopE distinguishes among its targets and which specific targets are critical for Yersinia survival in different tissues are unknown. A screen identifying YopE mutants in Yersinia pseudotuberculosis t...
|
PMID: 20148901
PDF is available here.
PDF is available here.
Cellular Microbiology (12)7 2010
Abstract
We found that YopE also inhibited reactive oxygen species (ROS) production and inactivated Rac2. How YopE distinguishes among its targets and which specific targets are critical for Yersinia survival in different tissues are unknown. A screen identifying YopE mutants in Yersinia pseudotuberculosis t...
|
PMID: 20148901
PDF is available here.
PDF is available here.
Infection and Immunity (78)7 2010
Abstract
We have previously shown that pathogenic leptospiral strains are able to bind C4b binding protein (C4BP). Surface-bound C4BP retains its cofactor activity, indicating that acquisition of this complement regulator may contribute to leptospiral serum resistance. In the present study, the abilities of...
|
PMID: 20404075
PDF is available here.
PDF is available here.
Infection and Immunity (78)7 2010
Abstract
We demonstrate that LbpB is also released into the culture medium. We identified NalP, an autotransporter known to be involved in the processing of other autotransporters, as the protease responsible for LbpB release. This release of LbpB reduced the complement-mediated killing of the bacteria when...
|
PMID: 20421383
PDF is available here.
PDF is available here.
Infection and Immunity (78)7 2010
Abstract
We demonstrated that a surprisingly large fraction of Neisseria meningitidis disease isolates are lipid A mutants, due to inactivating mutations in the lpxL1 gene. The lpxL1 mutants activate human TLR4 much less efficiently than wild-type bacteria, which may be advantageous by allowing them to escap...
|
PMID: 20439476
PDF is available here.
PDF is available here.
Infection and Immunity (78)7 2010
Abstract
We report results of an immunoproteomics approach to antigen discovery with ETEC strain H10407. Immunoblotting of proteins separated by two-dimensional electrophoresis (2DE) with sera from mice infected with strain H10407 or with convalescent human sera obtained following natural ETEC infections dem...
|
PMID: 20457787
PDF is available here.
PDF is available here.
Infection and Immunity (78)7 2010
Abstract
We identified NlpI as a novel bacterial determinant contributing to E. coli K1 interaction with HBMECs. The deletion of nlpI did not affect the expression of the known bacterial determinants involved in E. coli K1-HBMEC interaction, such as type 1 fimbriae, flagella, and OmpA, and the contribution o...
|
PMID: 20421385
PDF is available here.
PDF is available here.
Infection and Immunity (78)7 2010
Abstract
We have previously shown that Lactobacillus jensenii, one of the most prevalent microorganisms in the healthy human vaginal tract, can inhibit gonococcal adherence to epithelial cells in culture. Here we examined the role of the epithelial cells and the components of L. jensenii involved in the inhi...
|
PMID: 20385752
PDF is available here.
PDF is available here.
Infection and Immunity (78)7 2010
Abstract
We investigated the role of PRN in pathogenesis using B. bronchiseptica and natural-host animal models. A Deltaprn mutant did not differ from wild-type B. bronchiseptica in its ability to adhere to epithelial and macrophage-like cells in vitro or to establish respiratory infection in rats but was cl...
|
PMID: 20421378
PDF is available here.
PDF is available here.
Infection and Immunity (78)7 2010
Abstract
We demonstrated that expression of the surface lipoprotein-encoding gene bba07 is induced by an elevated temperature and a reduced pH during in vitro cultivation, as well as during nymphal tick feeding. Expression of bba07 is regulated by the Rrp2-RpoN-RpoS pathway, a central regulatory network that...
|
PMID: 20421380
PDF is available here.
PDF is available here.
Infection and Immunity (78)7 2010
Abstract
We investigated the role of PRN in pathogenesis using B. bronchiseptica and natural-host animal models. A Deltaprn mutant did not differ from wild-type B. bronchiseptica in its ability to adhere to epithelial and macrophage-like cells in vitro or to establish respiratory infection in rats but was cl...
|
PMID: 20421378
PDF is available here.
PDF is available here.
Infection and Immunity (78)7 2010
Abstract
We demonstrated that expression of the surface lipoprotein-encoding gene bba07 is induced by an elevated temperature and a reduced pH during in vitro cultivation, as well as during nymphal tick feeding. Expression of bba07 is regulated by the Rrp2-RpoN-RpoS pathway, a central regulatory network that...
|
PMID: 20421380
PDF is available here.
PDF is available here.
Infection and Immunity (78)7 2010
Abstract
We investigated the role of PRN in pathogenesis using B. bronchiseptica and natural-host animal models. A Deltaprn mutant did not differ from wild-type B. bronchiseptica in its ability to adhere to epithelial and macrophage-like cells in vitro or to establish respiratory infection in rats but was cl...
|
PMID: 20421378
PDF is available here.
PDF is available here.
Infection and Immunity (78)7 2010
Abstract
We demonstrated that expression of the surface lipoprotein-encoding gene bba07 is induced by an elevated temperature and a reduced pH during in vitro cultivation, as well as during nymphal tick feeding. Expression of bba07 is regulated by the Rrp2-RpoN-RpoS pathway, a central regulatory network that...
|
PMID: 20421380
PDF is available here.
PDF is available here.
Infection and Immunity (78)7 2010
Abstract
We investigated the role of PRN in pathogenesis using B. bronchiseptica and natural-host animal models. A Deltaprn mutant did not differ from wild-type B. bronchiseptica in its ability to adhere to epithelial and macrophage-like cells in vitro or to establish respiratory infection in rats but was cl...
|
PMID: 20421378
PDF is available here.
PDF is available here.
Infection and Immunity (78)7 2010
Abstract
We demonstrated that expression of the surface lipoprotein-encoding gene bba07 is induced by an elevated temperature and a reduced pH during in vitro cultivation, as well as during nymphal tick feeding. Expression of bba07 is regulated by the Rrp2-RpoN-RpoS pathway, a central regulatory network that...
|
PMID: 20421380
PDF is available here.
PDF is available here.
Infection and Immunity (78)7 2010
Abstract
We investigated the role of PRN in pathogenesis using B. bronchiseptica and natural-host animal models. A Deltaprn mutant did not differ from wild-type B. bronchiseptica in its ability to adhere to epithelial and macrophage-like cells in vitro or to establish respiratory infection in rats but was cl...
|
PMID: 20421378
PDF is available here.
PDF is available here.