Find your PDFs fast.
Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Oligoclonal Bands (0):
Recent article
Oligoclonal Bands
Abstract
The occurrence of OB could be a potential favorable prognostic marker after transplantation due to the prolonged survival observed. Close follow-up of anomalous protein bands, either in serum or urine, is essential due to the additional difficulty in interpretation when the therapeutic response and...
|
PMID: 20450334
PDF is available here.
PDF is available here.
| < More recent | Older article > |
Abstract
Abstract
Abstract
Abstract
Abstract
Abstract
Abstract
Abstract
Optic neuropathy (ON) is defined as the reduction of vision due to inflammatory lesion of the optic nerve. The patient with ON has to be evaluated clinically but also with complex techniques (magnetic resonance imaging, visual evoked potentials, cerebrospinal fluid examination) because ON could be t...
|
PMID: 20540361
PDF is available here.
PDF is available here.
Abstract
These results suggest that the frequency of CSF OCB is much lower in Brazilian MS patients from São Paulo city than that reported in MS series from Caucasian populations....
|
PMID: 20069212
PDF is available here.
PDF is available here.
Journal of Neuroimmunology (211)1-2 2009
Abstract
We studied oligoclonal bands in 424 MS patients. Most primary progressive (PPMS) patients showed serum OCGB with additional bands in CSF. Conversely, most RRMS and secondary progressive (SPMS) patients showed OCGB exclusively in CSF (p<0.0001). Moreover, no PPMS patient presented LS-OCMB, while 31%...
|
PMID: 19443047
PDF is available here.
PDF is available here.
Autoimmunity (42)8 2009
Abstract
Increasing evidence indicates an involvement of B cells in multiple sclerosis (MS). However, little is known about antigenic targets recognized by antibodies present in blood and cerebrospinal fluid (CSF) of MS patients. This study was therefore aimed at identifying the antigen reactivity of antibod...
|
PMID: 19835487
PDF is available here.
PDF is available here.
Revista de Neurologia (48)2 2009
[Pseudomigraine with pleocytosis: a pediatric case with cerebellar ataxia and mumps virus infection]
Abstract
Revista de Neurologia (48)7 2009
Abstract
INTRODUCTION: Spinal cord involvement is a rare presentation of grade II astrocytomas. Nevertheless, differentiation from inflammatory demyelinating diseases of the central nervous system can be challenging in some clinical situations. A patient with an optic-spinal syndrome due to a fibrillary astr...
|
PMID: 19319816
PDF is available here.
PDF is available here.
Revista de Neurologia (48)1 2009
Abstract
Biomedical Papers (152)2 2008
Abstract
No positive correlation between the IgG index and the number of OCB was found. Mann-Whitney test also failed to demonstrate any significant difference of the IgG index values in patients both with the OCB number > or = 2 and < 2. CONCLUSION: This study did not confirm any correlation between the IgG...
|
PMID: 19219215
PDF is available here.
PDF is available here.
Abstract
We aimed to disclose possible factors contributing to the development of such MRI features. METHOD: Genotyping of HLA-DRB1 and -DPB1 alleles was performed in 121 consecutive Japanese patients with clinically definite MS based on the Poser criteria and 125 healthy controls. Possible factors associate...
|
PMID: 18952831
PDF is available here.
PDF is available here.
Abstract
Lipid-specific immunoglobulin M bands were detected in the CSF of 24 of 81 patients with MS and were absent in the CSF of all headache controls. Median time to conversion to a secondary progressive course was 11 years in patients with bands and 22 years in patients without bands. Median time to an E...
|
PMID: 18755821
PDF is available here.
PDF is available here.
Abstract
The persistence of CSF lymphocyte activation markers sCD27 and intrathecal oligoclonal IgG bands after maximum immunoablative treatment indicates that complete eradication of activated lymphocytes from the CNS has not been established. This is paralleled by disease progression observed in several st...
|
PMID: 18223013
PDF is available here.
PDF is available here.
Nature Medicine (14)6 2008
Abstract
We describe a method for correlating the immunoglobulin (Ig) proteomes with the B cell transcriptomes in human fluid and tissue samples, using multiple sclerosis as a paradigm. Oligoclonal Ig bands and elevated numbers of clonally expanded B cells in the cerebrospinal fluid (CSF) are diagnostic hall...
|
PMID: 18488038
PDF is available here.
PDF is available here.
Parassitologia (50)1-2 2008
Abstract
With the advent of the highly active antiretroviral therapy (HAART), the natural course of HIV infection has markedly changed and opportunistic infections including toxoplasmosis have declined and modified in presentation, outcome and incidence. However, TE is a major cause of morbidity and mortalit...
|
PMID: 18693556
PDF is available here.
PDF is available here.
Abstract
A 15-year-old girl presented to our emergency department with dizziness, anorexia, nausea, and malaise. Clinical examination and magnetic resonance imaging studies showed characteristic features of multiple sclerosis. Surprisingly, a diagnostic lumbar puncture showed significant intracranial hyperte...
|
PMID: 18539995
PDF is available here.
PDF is available here.
Journal of the Neurological Sciences (268)1-2 2008
Abstract
Unlike paraneoplastic LE, VGKC-LE is not frequently associated with intrathecal Ig production or markedly elevated white cell counts. Thus, normal CSF findings do not preclude the disease. VGKC-Ab should, therefore, be determined whenever LE is clinically suspected, irrespective of the presence or a...
|
PMID: 18068189
PDF is available here.
PDF is available here.
Journal of the Neurological Sciences (268)1-2 2008
Abstract
Our results confirm previous studies demonstrating IgG synthesis against onconeuronal antigens by intrathecal B-cell clones in PNS and extend this observation to patients with anti-Ri syndrome. The pathogenic relevance of these antibodies, however, is further challenged by the finding that specific...
|
PMID: 18096187
PDF is available here.
PDF is available here.
Abstract
Factors predicting incomplete recovery are more closely linked to the characteristics of the single relapse (extension and duration of tissue damage) than to the patient's genetic and environmental background....
|
PMID: 18208889
PDF is available here.
PDF is available here.
Journal of Neurology (255)5 2008
Abstract
We evaluated clinical presentation, cerebrospinal fluid (CSF), and magnetic resonance imaging (MRI) in patients with late-onset multiple sclerosis (LOMS). Fifty-two patients with definitive multiple sclerosis (MS) diagnosed after the age of 50 years were identified between 1991 and 2002. Data pertai...
|
PMID: 18283394
PDF is available here.
PDF is available here.
Journal of Neurology (255)5 2008
Abstract
Abstract
Abstract
We identified 73 patients with a first-ever APTM admitted to our institution from January 1999 to June 2005. The follow-up time ranged from 12 to 90 months (mean follow-up 46 months). Patient demographics, clinical impairment at onset and after 3 months, ancillary tests including cerebrospinal fluid...
|
PMID: 18312402
PDF is available here.
PDF is available here.
Abstract
Presence of oligoclonal bands doubles the risk for having a second attack, independently of MRI, but does not seem to influence the development of disability....
|
PMID: 17881717
PDF is available here.
PDF is available here.
Abstract
Abstract
We describe here a characterization of these antibodies and study their role in MS progression. Fifty-four MS patients showing CSF-restricted OCMB were included in this study at disease onset and followed-up during 61.1 +/- 2.7 months. The specificity of OCMB and the CSF B-cell profile were investig...
|
PMID: 17942517
PDF is available here.
PDF is available here.
Neuroscience Letters (431)1 2008
Abstract
We compared the prevalence of C2370A single nucleotide polymorphism (SNP) in the 3' untranslated region (3'UTR) of the IL-23 receptor (IL23R) between 223 patients with relapsing-remitting multiple sclerosis (RRMS) and 200 healthy controls. The A2370A genotype was significantly over-represented among...
|
PMID: 18180107
PDF is available here.
PDF is available here.
Neurologist (14)1 2008
Abstract
Journal of Neurology (255)1 2008
Abstract
We studied 58 ATM patients with normal brain MRI at presentation for up to 5 years with serial neurologic and imaging studies. All patients underwent CSF analysis at onset which was defined positive if two or more IgG oligoclonal bands and/or elevated IgG index were present. Brain and spinal cord MR...
|
PMID: 18080852
PDF is available here.
PDF is available here.
Abstract
Typical multiple myeloma can be diagnosed precisely through lots of evaluations including the confirmation of the presence of increased clonal myeloma cells in bone marrow accompanied by monoclonal protein, cytopenia, bone diseases and renal disturbance. However, there still exists not a little diff...
|
PMID: 18069272
PDF is available here.
PDF is available here.
Pediatric Nephrology (22)11 2007
Abstract
We describe a child presenting with oligoclonal plasma IgM (1.2 g%) and nephrotic syndrome with focal segmental glomerulosclerosis. Oligoclonality was demonstrated by the analysis of the complementary determining region 3 (CDR 3) on immunoglobulin heavy chains and by two dimensional electrophoresis...
|
PMID: 17661091
PDF is available here.
PDF is available here.
Journal of Neurosurgery (107)5 2007
Abstract
The results of isoelectric focusing studies showed that CCM lesions had oligoclonal patterns of IgG unrelated to peripheral blood contamination, indicating selective synthesis of IgG within the lesions. This finding probably reflects a clonal expansion of B cells and/or plasmacytes in CCMs, an event...
|
PMID: 17977276
PDF is available here.
PDF is available here.
Neurological Sciences (28)4 2007
Abstract
In six patients with slowly progressive sporadic cerebellar ataxia and cortical multifocal action myoclonus, cerebrospinal fluid (CSF) IgG index was persistently very high (1.2-6.7) and numerous oligoclonal bands were detected. Progressive cognitive impairment and MRI cerebellar and cerebral atrophy...
|
PMID: 17690852
PDF is available here.
PDF is available here.
Clinical Chemistry (53)8 2007
Abstract
Abstract
We describe a case of encephalopathy in which the clinical picture and triphasic waves in the EEG indicated a metabolic cause. However, the illness was caused by neuroborreliosis. The occurrence of triphasic waves in the EEG is a strong evidence of metabolic encephalopathy, but triphasic waves are n...
|
PMID: 17661801
PDF is available here.
PDF is available here.
Abstract
The objective of this study was to investigate, whether the presence of oligoclonal immunoglobulin M bands (IgM-OCB) in cerebrospinal fluid (CSF) from patients with a clinically isolated syndrome (CIS), which is suggestive for the first clinical manifestation of multiple sclerosis (MS), anticipates...
|
PMID: 17662013
PDF is available here.
PDF is available here.
Abstract
Three women (aged 21-36 years) developed acute illnesses that were similar to epidemic encephalitis lethargica. Each presented with a neuropsychiatric disturbance that was succeeded by pyrexia, a fluctuating conscious state and involuntary movements including oculogyria. Cerebrospinal fluid examinat...
|
PMID: 16647855
PDF is available here.
PDF is available here.
Gastroenterology (133)1 2007
Abstract
Biliary atresia is associated with oligoclonal expansions of CD4(+) and CD8(+) T cells within liver and extrahepatic bile duct remnant tissues, indicating the presence of activated T cells reacting to specific antigenic stimulation. Future studies entail identifying the specific antigen(s) responsib...
|
PMID: 17631149
PDF is available here.
PDF is available here.
Abstract
Antibody-mediated inflammation is believed to contribute to tissue injury in multiple sclerosis (MS). The majority of patients with MS have oligoclonal bands (OCB), corresponding to antibodies against a variety of antigens, in their cerebrospinal fluid (CSF). The relation of CSF OCB and disease prog...
|
PMID: 17594338
PDF is available here.
PDF is available here.
Abstract
The CSF humoral immune response is more active among African Americans (AAs) than among Caucasian Americans (CAs) with multiple sclerosis. AAs also progress to ambulatory assistance earlier than CAs, but high immunoglobulin G index does not predict earlier progression to the disability endpoint....
|
PMID: 17606883
PDF is available here.
PDF is available here.
Abstract
We investigated cerebrospinal fluid (CSF) and sera from three patients with positive anti-CV2/CRMP5- and one patient with positive anti-amphiphysin serology. CSF and sera were previously adjusted to total IgG concentrations of 20 mg/l. All patients suffered from paraneoplastic neurological syndromes...
|
PMID: 17539943
PDF is available here.
PDF is available here.
Abstract
Abstract
The two parameters, OCBs and IgGIF are of less diagnostic value for MS in China....
|
PMID: 17489942
PDF is available here.
PDF is available here.
Abstract
A 10-year-old boy developed corticosteroid-responsive relapsing neurologic signs, including nystagmus and ataxia. MRI revealed multifocal T2 white matter hyperintensities; several were gadolinium-enhancing. CSF contained oligoclonal bands. Although the patient met criteria for multiple sclerosis (MS...
|
PMID: 17438221
PDF is available here.
PDF is available here.
Abstract
We suggest that RE might be presently underdiagnosed and should be suspected in cases of new onset hemiparesis. In this series, three out of five patients showed oligoclonal bands on examination of cerebrospinal fluid (CSF) which represented additional diagnostic hints towards an immune-mediated con...
|
PMID: 17388985
PDF is available here.
PDF is available here.
Abstract
We report the novel presence of oxidized phosphatidylcholine [1-palmitoyl-2-(5'-oxo)valeryl-sn-glycero-3-phosphorylcholine (POVPC)], a lipid associated with inflammatory diseases such as atherosclerosis and lung disease, in the brain of MS patients. The OxPC epitope was detected by Western blotting...
|
PMID: 17304573
PDF is available here.
PDF is available here.
Abstract
Thai MS patients had much more female occurrence, no family history, common optico-spinal form, long spinal MRI lesions and low positive CSF oligoclonal bands....
|
PMID: 17352356
PDF is available here.
PDF is available here.
Abstract
The sensitivity for detecting any inflammatory (autoimmune or infectious) CNS disease (52 patients) was 67% for IEF, 50% for IFPE and 29% for HRAGE. The sensitivity for detecting MS (14 patients) was 93%, 86% and 29% respectively. The sensitivity for detecting clinically isolated syndrome (eight pat...
|
PMID: 17212616
PDF is available here.
PDF is available here.
Abstract
Patients with suspected Creutzfeldt-Jakob disease (CJD) often have routine cerebrospinal fluid (CSF) analysis performed to exclude treatable inflammatory conditions; however, little information is available about the range of results obtained for CSF tests in patients with sporadic CJD and other tra...
|
PMID: 17250717
PDF is available here.
PDF is available here.
Abstract
A retrospective search in available patient files revealed that 6 of 6 (100.0 %) PAB-positive ON patients developed MS over time. Eight of 24 (33 %) PAB-negative ON patients developed MS over time and 47 % (14/30) of all ON patients developed MS. A series of patient CSF was analysed by ELISA to asse...
|
PMID: 17852796
PDF is available here.
PDF is available here.
Abstract
The performed analysis indicated that the differences in levels of anti-MOG IgG antibody in serum and cerebrospinal fluid from the patients with RRMS, PPMS or NIND were not statistically significant. CONCLUSION: The assay is not sensitive or specific enough to be used as a differential diagnostic to...
|
PMID: 16750597
PDF is available here.
PDF is available here.
Abstract
Abstract
We studied two extended families in which not only multiple sclerosis (MS) segregates, but also approximately 18% of the cerebrospinal fluid (CSF) investigated blood relatives have 'MS immunopathic trait', an oligoclonal CSF immunopathy similar to that seen in MS, but with no neurological symptoms....
|
PMID: 17262999
PDF is available here.
PDF is available here.
Abstract
B-cells may be involved at many levels in the pathogenesis of MS, starting from the earliest stage of antigen capture, continuing through the processes of tissue damage and even extending through to remyelination and repair. Recent advances in our understanding of normal B-cell biology and abnormal...
|
PMID: 17101076
PDF is available here.
PDF is available here.