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Reagins (0):
Recent article
Reagins
Abstract
I Hypersensitivity responses. The development of this type of allergy involves a series of events that begins with reaginic antibodies, mainly IgE and some IgG subclasses. These reaginic antibodies bind with high affinity, via the Fc portion, to FcepsilonRI receptors on the membrane of mast cells an...
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PMID: 20012188
PDF is available here.
PDF is available here.
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Abstract
One hundred eighty subjects experienced 231 cases of syphilis. The median follow-up time was 5.3 years. A total of 71 episodes of serologic failure were documented. A CD4 cell count of <200 cells/mL at the time of syphilis diagnosis was associated with an increased risk of serologic failure (adjuste...
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PMID: 18532887
PDF is available here.
PDF is available here.
Abstract
The aim of the study was to determine the characteristics of primary and late latent syphilis cases that were non-reactive on initial screening by rapid plasma reagin (RPR) but reactive by treponemal tests. RPR test results of all primary and late latent syphilis cases in the province of Alberta, Ca...
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PMID: 18574118
PDF is available here.
PDF is available here.
Abstract
We describe 4 patients (age, >50 years) with secondary syphilis. All patients presented with ocular syphilis, and 2 presented with syphilis-negative rapid plasma reagin titers due to a prozone phenomenon. Three male patients reported sildenafil use. The presentation of these patients with ocular syp...
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PMID: 18462103
PDF is available here.
PDF is available here.
Abstract
The incidence of seroresistance was not significantly different among patients with different ages and genders, but was significantly different among patients with different disease courses, antibody titers, and medications. Patients with a baseline serum rapid plasma reagin (RPR) titer of greater t...
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PMID: 18686618
PDF is available here.
PDF is available here.
Sexually Transmitted Diseases (34)7 Suppl 2007
Abstract
It is feasible to introduce rapid syphilis testing in settings without laboratory services at a small incremental cost per woman screened. In settings with laboratories, the cost of ICS is similar to that of RPR....
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PMID: 17220812
PDF is available here.
PDF is available here.
Sexually Transmitted Diseases (34)7 Suppl 2007
Abstract
In settings of high maternal syphilis prevalence, on-site antenatal screening with ICS is a cost-effective approach to reduce the incidence of congenital syphilis....
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PMID: 17308502
PDF is available here.
PDF is available here.
Sexually Transmitted Diseases (34)7 Suppl 2007
Abstract
The on-site ICS test can reduce syphilis-related adverse outcomes of pregnancy through accurate diagnosis and immediate treatment of pregnant women with syphilis....
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PMID: 17139234
PDF is available here.
PDF is available here.
Zhonghua Yixue Zazhi (87)24 2007
Abstract
The serum sensitivity and specificity of Abbott Determine Syphilis TP test were 100% and 98.4% respectively. The serum sensitivity and specificity of RPR test were 65.1% and 98.4% respectively. CONCLUSION: The sensitivity of the rapid ELISA based on recombinant Tp antigen is significantly higher tha...
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PMID: 17825160
PDF is available here.
PDF is available here.
Abstract
Of the 450 HIV-positive patients with syphilis, 288 (64%) did not have documented follow-up serologies and 129 (28.5%) met the inclusion criteria; 168 (17%) of 1000 known HIV-negative patients were similarly eligible. There were 22 failures in the HIV-positive group and 5 in the HIV-negative group (...
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PMID: 16943224
PDF is available here.
PDF is available here.
Abstract
Twenty-six of 112 had neurosyphilis. Neurologic manifestations and serum rapid plasma reagin (RPR) were associated with neurosyphilis (P = 0.036, P = 0.018, respectively). In multivariate analysis, log(2)RPR was still associated with neurosyphilis (P = 0.005). In patients without neurologic manifest...
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PMID: 16865051
PDF is available here.
PDF is available here.
Abstract
Abstract
We conclude that detection of specific 47-kDa T. pallidum antibodies can be used to diagnose primary syphilis. By RPR, antibodies disappear in 6-24 months after treatment in many patients, suggesting that a change in titer may be an indicator of treatment success....
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PMID: 17040431
PDF is available here.
PDF is available here.
Abstract
Syphilis was common, associated with HIV infection, and less responsive to therapy in those with initial RPR titers
PDF is available here.
PDF is available here.
Abstract
Forty-one patients were included. CD4 cell count decreased significantly during infection in patients with primary and secondary stages of syphilis (mean 106 cells/mm, P = 0.03). Treatment of syphilis was associated with an increase in the CD4 cell count and a decrease in HIV-RNA in the overall grou...
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PMID: 16505739
PDF is available here.
PDF is available here.
Abstract
For active syphilis, the sensitivity of the ICS was 95.3% at the reference laboratory, and 84.1% at the health facility. The sensitivity of the RPR at the health facility was 70.7%. Specificity and positive and negative predictive values showed a similar pattern. The ICS outperformed RPR in all comp...
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PMID: 16501726
PDF is available here.
PDF is available here.
Abstract
False-positive reactions in the Venereal Disease Research Laboratory test are well known, whereas a positive fluorescent treponemal antibody absorption assay is rarely thought to be a false positive. The non-recognition of serological false-positive tests for syphilis may have negative prognostic an...
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PMID: 17083877
PDF is available here.
PDF is available here.
Abstract
Rapid plasma reagin (RPR) titers were periodically examined during and after treatment in three rabbits clinically diagnosed with rabbit syphilis. RPR titers remained positive after clinical recovery and then gradually declined. Of the two rabbits inoculated experimentally, one showed clinical signs...
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PMID: 16082127
PDF is available here.
PDF is available here.
Abstract
These results supported the specific relationship between clinical signs and RPR titers. Histopathological examination of the skin lesion from the symptomatic rabbit revealed spirochetes....
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PMID: 15699599
PDF is available here.
PDF is available here.
Abstract
Our recommendation is that the Determine test be made available in areas of the country where VDRL is unavailable or where logistics do not allow for test results to be available early enough to make a difference to the care of th pregnant woman and her fetus....
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PMID: 17212063
PDF is available here.
PDF is available here.
Abstract
The objective of this prospective pilot study was to evaluate the response of HIV-infected patients with asymptomatic syphilis to one of two intensive antibiotic treatment regimens. Thirty-one HIV-infected patients with serum rapid plasma reagin titre > or =1:4 and no clinical findings of syphilis w...
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PMID: 15117503
PDF is available here.
PDF is available here.
Abstract
Sixty-five subjects (20.1%) had neurosyphilis. Early syphilis increased the odds of neurosyphilis in univariate but not multivariate analyses. In multivariate analyses, serum rapid plasma reagin (RPR) titer > or =1 : 32 increased the odds of neurosyphilis 10.85-fold in human immunodeficiency virus (...
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PMID: 14745693
PDF is available here.
PDF is available here.
Abstract
Cellular immunity imbalance and immune suppression can be present in treated syphilis patients with persistent positive RPR and the risk to transmission, which may lower the host ability to resist and clear Treponema pallidum and is associated with the difficulty in treating syphilis patients and th...
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PMID: 14678898
PDF is available here.
PDF is available here.
Abstract
Reactor grids are widely used and may exclude persons with infectious syphilis from health department evaluation, especially men. The impact of reactor grid use on syphilis control and surveillance in the United States should be evaluated....
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PMID: 12897688
PDF is available here.
PDF is available here.
Abstract
Abstract
The appropriateness of syphilis screening using RPR testing in antenatal clinics and health centres should be questioned if there is a low prevalence in the population, conditions for testing are poor, and resources limited. There is still an urgent need for an appropriate rapid syphilis test for fi...
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PMID: 12181468
PDF is available here.
PDF is available here.
Abstract
Cumulative response rates were as follows: benzathine penicillin G, 86% (12 of 14); azithromycin, 2.0-g single dose, 94% (16 of 17); and azithromycin, two 2.0-g doses given 1 week apart, 83% (24 of 29). Therapy failed for one patient treated with benzathine penicillin and one patient treated with th...
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PMID: 12172535
PDF is available here.
PDF is available here.
Mikrobiyoloji bulteni (36)1 2002
Abstract
Transfusion of blood and blood products is a widely used method for therapy in medicine, however it may result with the transmission of infectious agents from donor to recipient. In order to achieve safe blood transfusions and to minimize post-transfusion infections, several screening tests for infe...
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PMID: 12476771
PDF is available here.
PDF is available here.
Abstract
The aim of this study was to evaluate the performance of rapid plasma reagin (RPR) testing using expired and adversely stored antigen reagent. The sensitivity of RPR using antigen stored at 36 degrees C was compared at 3-monthly intervals with RPR using fresh antigen on 116 sera reactive by RPR and...
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PMID: 11368802
PDF is available here.
PDF is available here.
Abstract
We conclude that there is a need for improved services for STD prevention and RTI/STD management in rural Bali, and for condom promotion....
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PMID: 11177482
PDF is available here.
PDF is available here.
Abstract
Nontreponemal antibody tests such as the Venereal Disease Research Laboratory (VDRL) test are carried out on serum and widely used as screening tests for syphilis. The aim of the present study was to develop a screening test for syphilis making use of whole blood and VDRL liposomes. Antibody to huma...
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PMID: 10970393
PDF is available here.
PDF is available here.
Journal of Rheumatology (27)8 2000
Abstract
Abstract
We compared the microhemagglutination assay for Treponema pallidum (MHA-TP), a treponemal test, with two other treponemal tests, the Serodia Treponema pallidum particle agglutination (TP-PA) assay and the Captia Syphilis-G enzyme immunoassay, using 390 clinical serum samples. We also compared two no...
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PMID: 10878040
PDF is available here.
PDF is available here.
Abstract
Mechanisms by which subjects have been sensitized, still unknown, happen in different times according to family history. These findings suggest several genetic factors....
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PMID: 10191890
PDF is available here.
PDF is available here.
Abstract
These results support the hypothesis that mast cells play a role in the early stage of atherosclerosis and suggest that this animal model could be useful for evaluating the role of the diet in immune-related atherogenesis....
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PMID: 10192920
PDF is available here.
PDF is available here.
Transfusion (39)2 1999
Abstract
The change to the PK-TP test resulted in a lower repeatedly reactive rate, better prediction that a confirmed-positive test for syphilis would occur in testing in the FTA-ABS, fewer donations lost, and comparable deferral rates. Because of the high rate of reactivity to serologic testing for syphili...
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PMID: 10037133
PDF is available here.
PDF is available here.
Clinica Chimica Acta (279)1-2 1999
Abstract
Abstract
Abstract
Abstract
Cats, naturally or experimentally infected with Toxocara cati were immunised with dinitrophenylated ascaris antigen (DNP-Asc). All cats developed immediate skin reactivity to DNP coupled to bovine serum albumin (DNP-BSA) and the sera of the nine cats had a heat labile homocytotropic antibody detecta...
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PMID: 9656457
PDF is available here.
PDF is available here.
Abstract
Sera from 10 cats with symptoms consistent with atopy, from 15 normal household cats and from 11 laboratory maintained cats were assessed for allergen-specific IgE and IgG to Dermatophagoides farinae (DF) by enzyme-linked immunosorbent assay (ELISA). In addition, 10 normal cats were immunised with D...
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PMID: 9656458
PDF is available here.
PDF is available here.
Abstract
The effect of chemical denaturation of ovalbumin (OVA) on the induction of oral tolerance of reaginic antibody responses was studied. Both urea-denatured OVA (UD-OVA) and carboxymethylated UD-OVA (CM-OVA) were purified by centrifugation. When compared with OVA and UD-OVA, CM-OVA had the least sensit...
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PMID: 9627132
PDF is available here.
PDF is available here.
Abstract
We present an unusual case, in which a woman presenting with markedly decreased fetal movements at 29 weeks gestation following a recent increase in fundal height was noted sonographically to have fetal hydrops consisting of scalp edema, marked hepatomegaly, ascites, and polyhydramnios. No lethal st...
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PMID: 9565220
PDF is available here.
PDF is available here.
Abstract
In the event of rapid plasma reagin titres of 1:8 and higher, indicative of active syphilis, the on-site rapid plasma reagin test had a sensitivity of 90.5%. The test had a sensitivity of 100% if the rapid plasma reagin titres were 1:16 and higher. CONCLUSION: The on-site rapid plasma reagin test id...
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PMID: 9539935
PDF is available here.
PDF is available here.
Statistics in Medicine (16)18 1997
Abstract
We propose a method to predict non-treponemal seroreversion based on short term response. To develop and illustrate this method, we used data from 370 individuals with infectious syphilis. Individual serologic response appears to be a linear function of (log) time, suggesting the possibility of usin...
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PMID: 9308135
PDF is available here.
PDF is available here.
Allergie et Immunologie (Paris) (29 Spec No) 1997
Abstract
After recalling the medical reluctance as well as the risks that there are in complete elimination of milk in infants, the author presents several clinical pictures and then a classification of the immunological types. Allergic shock of neonates, digestive and extra-digestive (skin and respiratory a...
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PMID: 9376082
PDF is available here.
PDF is available here.
Dermatology (195 Suppl 2) 1997
Abstract
We are drawing attention to the high isolation rate of Staphylococcus aureus when starting disinfectant treatment combined with topical steroid therapies for the purpose of killing S. aureus. As a result, we examined many patients in whom almost a complete remission was obtained even after short per...
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PMID: 9403258
PDF is available here.
PDF is available here.
Abstract
Abstract
We sought to determine: (1) the perinatal outcomes in the subsequent pregnancy; (2) the natural history of serologic titers over the course of the two pregnancies; and (3) the incidence and risk factors for delivering an infant with congenital syphilis in the subsequent pregnancy. Over a five-year p...
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PMID: 8989486
PDF is available here.
PDF is available here.
Genitourinary medicine (71)5 1995
Abstract
OBJECTIVES--To compare characteristics of syphilis serological reactivity in HIV positive (+) and HIV negative (-) female sex workers, as well as the serological response to therapy after treatment with intramuscular benzathine penicillin, 2.4 million U weekly, for three consecutive weeks. METHODS--...
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PMID: 7490041
PDF is available here.
PDF is available here.
Journal of Trauma (39)3 1995
Abstract
We evaluated the presence of human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV), and rapid plasma reagin (RPR) among patients admitted to our trauma unit from April 15 to June 30, 1993. Of 984 patients tested, we found 255 (26%) had evidence of exposure to one or mo...
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PMID: 7473920
PDF is available here.
PDF is available here.
Abstract
Annales de medecine interne (146)8 1995
Abstract
This study was conducted in 1,091 children and adolescents submitted to an allergy check-up for respiratory symptoms. All subjects had a research of IgE for Dermatophagoides pteronyssinus, cat and timothy grass pollen by CAP-System Pharmacia. Three hundred subjects had a personal history of atopic d...
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PMID: 8734080
PDF is available here.
PDF is available here.
Abstract
The prevalence of false-positive reactions for syphilis (reactive rapid plasma reagin [RPR] test and nonreactive fluorescent treponemal antibody absorption [FTA-ABS] test) among patients at sexually transmitted disease (STD) clinics was assessed to evaluate the association between false-positive RPR...
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PMID: 7527828
PDF is available here.
PDF is available here.
Toxicology (91)3 1994
Abstract
We have investigated the potential of the inbred Brown Norway (BN) rat as a model for food allergy using two different antigens, ovalbumin (OA) and semi-skimmed milk (SSM). The use of milk-free diet prior to and during exposure to SSM was a key factor in the induction of sensitisation to milk protei...
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PMID: 8079365
PDF is available here.
PDF is available here.
Annals of Internal Medicine (121)2 1994
Abstract
The clinical presentation of syphilis in patients with HIV infection differs from that of patients without HIV infection in that patients with HIV infection present more often in the secondary stage and those with secondary syphilis are more likely to have chancres....
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PMID: 7912483
PDF is available here.
PDF is available here.
Abstract
Abstract
Reported are the results of a comparative study of two procedures for the rapid plasma reagin (RPR) test for syphilis serology: in one approach a mechanical rotator was used and in the other, hand rotation was employed. Both procedures were performed on 327 sera. The agreement between both was 98.8%...
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PMID: 7955023
PDF is available here.
PDF is available here.
Abstract
We recommend screening for syphilis at the initial antenatal visit and rescreening at the time of delivery in areas such as ours....
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PMID: 8191324
PDF is available here.
PDF is available here.
Abstract
STUDY OBJECTIVE. To determine the sensitivity, specificity, negative predictive value and positive predictive value of the rapid plasma reagin (RPR) test as performed on site in an antenatal clinic to facilitate immediate diagnosis and treatment of maternal syphilis. DESIGN. Open, descriptive study....
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PMID: 8191323
PDF is available here.
PDF is available here.