Find your PDFs fast.
Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Cytoskeletal Proteins (14):
Recent article
Cytoskeletal Proteins
Proteomics (11)18 2011
Abstract
This review covers progress in proteome research on Mycoplasma pneumoniae made over the last 5 years. This bacterium is one of the smallest known self-replicating bacteria. With fewer than 700 proposed proteins, it is well suited to a comprehensive proteome analysis. While all of the...
|
PMID: 21751371
PDF is available here.
PDF is available here.
| < More recent | Older article > |
Journal of Proteomics (74)8 2011
Abstract
We have analyzed the adaptive responses of Lupinus albus roots to long-term B deficiency. Large morphological differences were observed between plants grown with or without B, and 265 polypeptides were found to be responsive to B deficiency out of a total of 406 polypeptides detected by two-dimensio...
|
PMID: 21406259
PDF is available here.
PDF is available here.
Developmental Cell (21)2 2011
Abstract
We show that the kinesin-like myosin passenger-protein Smy1 interacts with the FH2 domain of the formin Bnr1 to decrease rates of actin filament elongation, which is distinct from the formin displacement activity of Bud14. In vivo analysis of smy1Δ mutants demonstrates that this "damper" mechanism...
|
PMID: 21839918
PDF is available here.
PDF is available here.
Abstract
Idiopathic pulmonary fibrosis (IPF) is the most common form of the idiopathic interstitial pneumonias and remains a disease with a poor prognosis. Familial interstitial pneumonia (FIP) occurs when 2 or more individuals from a given family have an idiopathic interstitial pneumonia. FI...
|
PMID: 21613931
PDF is available here.
PDF is available here.
Transplantation (91)9 2011
Abstract
We investigated in vivo the effects of sirolimus on nephrin, podocin, CD2ap, and actin protein expression. Slit diaphragm (SD)-associated protein expressions were evaluated in T0 and T2 biopsies. The same analysis was performed in cultured human podocytes treated with different doses of sirolimus (5...
|
PMID: 21364499
PDF is available here.
PDF is available here.
Transplantation (91)9 2011
Abstract
We investigated in vivo the effects of sirolimus on nephrin, podocin, CD2ap, and actin protein expression. Slit diaphragm (SD)-associated protein expressions were evaluated in T0 and T2 biopsies. The same analysis was performed in cultured human podocytes treated with different doses of sirolimus (5...
|
PMID: 21364499
PDF is available here.
PDF is available here.
Developmental Cell (20)5 2011
Abstract
We show that yeast dynein offloads from microtubule plus ends to the daughter cell cortex. Mutants with an engineered peptide inserted between the tail domain and the motor head retain wild-type motor activity but exhibit enhanced offloading and cortical targeting. Conversely, shortening the "neck"...
|
PMID: 21571221
PDF is available here.
PDF is available here.
Cellular Microbiology (13)4 2011
Abstract
I investigated the regulation of host cell actin dynamics in T. annulata-transformed macrophages and how this affects host cell morphology and motility. T. annulata was found to promote the formation of filamentous-actin-rich podosome-type adhesions (PTAs) and lamellipodia, and to establish a polari...
|
PMID: 21091599
PDF is available here.
PDF is available here.
Abstract
We show that Notch1 and its ligand Jagged1 are present at the synapse, and that Notch signaling in neurons occurs in response to synaptic activity. In addition, neuronal Notch signaling is positively regulated by Arc/Arg3.1, an activity-induced gene required for synaptic plasticity. In Arc/Arg3.1 mu...
|
PMID: 21315255
PDF is available here.
PDF is available here.
Abstract
We hypothesized that in the esophagus, immunohistochemistry for smoothelin would differentiate the NMM from the TMM.
Thirty cases of EMRs for Barrett esophagus-related neoplasia were retrieved from the archives of the pathology department, St Michael's Hospital. Immunohistochemical staining for smoo...
|
PMID: 21164287
PDF is available here.
PDF is available here.
Abstract
We found expression of CD43 induced cell rounding, inhibition of cell re-attachment, augmentation of microvilli, and phosphorylation of ERM in HEK293T cells. Mutant studies revealed the ectodomain of CD43, but not the intracellular domain, essential and sufficient for all these phenomena. We also fo...
|
PMID: 21045567
PDF is available here.
PDF is available here.
Abstract
We use Sla1p as a model to describe approaches for adaptor-clathrin interaction studies. We focus on live cell fluorescence microscopy, GST-pull down, and co-immunoprecipitation methods....
|
PMID: 21307828
PDF is available here.
PDF is available here.
Abstract
We used new domain-specific antibodies and small interfering RNA technology to uncover physiological functions of kindlin-2 in human dermal fibroblasts in vitro and in adult skin in situ. In primary dermal fibroblasts, kindlin-2 is essential for the integrin clustering and activation, and it regulat...
|
PMID: 20861856
PDF is available here.
PDF is available here.
Biochemical Journal (433)2 2010
Abstract
AE1 (anion exchanger 1) and protein 4.2 associate in a protein complex bridging the erythrocyte membrane and cytoskeleton; disruption of the complex results in unstable erythrocytes and HS (hereditary spherocytosis). Three HS mutations (E40K, G130R and P327R) in cdAE1 (the cytoplasmic domain of AE1)...
|
PMID: 21039340
PDF is available here.
PDF is available here.
Journal of Glaucoma (19)9 2010
Abstract
To determine the concentration of myocilin in primary open-angle glaucoma (POAG) and pseudoexfoliation glaucoma (PEXG) aqueous humor.
Aqueous humor was collected during surgery from patients with POAG, PEXG, and elective cataract removal (control). Volume-equivalent aqueous samples were separated on...
|
PMID: 20179615
PDF is available here.
PDF is available here.
Abstract
We hypothesized that mutations in pyrin may affect Siva-mediated apoptosis. The confirmation of this hypothesis would be of a great biological significance since it would be demonstrated a connection between apoptosis and inflammation. We used homology modeling to construct a 3-D model of Siva prote...
|
PMID: 20934406
PDF is available here.
PDF is available here.
Nucleic Acids Research (38)20 2010
Abstract
We therefore designed a novel DNA-based targeted sequencing approach to screen systematically for fusions within the 90 human TKs; it should detect 92% of known TK fusions. We deliberately paired 'in-solution' DNA capture with 454 sequencing to minimize starting material requirements, take advantage...
|
PMID: 20587502
PDF is available here.
PDF is available here.
Abstract
We found that Arc increases spine density and regulates spine morphology by increasing the proportion of thin spines. Furthermore, Arc specifically reduces surface GluR1 internalization at thin spines, and Arc mutants that fail to facilitate AMPAR endocytosis do not increase the proportion of thin s...
|
PMID: 20921410
PDF is available here.
PDF is available here.
Neuroscience (170)2 2010
Abstract
In this study, the expression patterns of zif268 and activity-regulated cytoskeleton-associated gene (arc) were investigated in the basolateral amygdala (BLA) and dorsal hippocampal (dHPC) subregions during context-induced drug-seeking following 22 h or 15 d abstinence from cocaine self-administrati...
|
PMID: 20654701
PDF is available here.
PDF is available here.
Acta Cardiologica (65)5 2010
Abstract
OBJECTIVE; ; The objective of this study was to identify developmental changes in vascular smooth muscle cells (VSMC) during aneurysm formation using an elastase-induced rabbit carotid artery aneurysm model.
- Aneurysms were induced in carotid arteries of rabbits by exposure to elastase. Tissues fro...
|
PMID: 21125970
PDF is available here.
PDF is available here.
Abstract
We report eight homologs of mical family genes in zebrafish and their expression profiles during embryonic development. Consistent with the findings in Drosophila and mammals, most zebrafish mical family genes display expression in neural and musculature systems. In addition, five mical homologs are...
|
PMID: 21035094
PDF is available here.
PDF is available here.
Abstract
Anticancer Research (30)10 2010
Abstract
We examined whether epigenetic silencing of target of methylation induced silencing 1 (TMS1) contributes to resistance to chemotherapy in pancreatic cancer.
Methylation analysis was performed by methylation-specific PCR (MS-PCR) and gene expression was analyzed by quantitative reverse transcriptase...
|
PMID: 21036703
PDF is available here.
PDF is available here.
Cytoskeleton (67)9 2010
Abstract
We reported a formin homology sequence and actin assembly activity in association with macrophage beta-3 integrin. In this study we demonstrate by quantitative reverse transcriptase polymerase chain reaction and Western blotting that the formin FRL1 is specifically upregulated during monocyte differ...
|
PMID: 20617518
PDF is available here.
PDF is available here.
Abstract
We showed that ezrin and RhoGDI1 are expressed in human testes. Thus, we sought to determine whether the ezrin-RhoGDI1-actin-membrane protein network has a role in human sperm capacitation. Our results by Western blot indicate that ezrin is activated by phosphorylation of the threonine567 residue du...
|
PMID: 20711218
PDF is available here.
PDF is available here.
Journal of Biological Chemistry (285)33 2010
Abstract
We examined a mechanism of nephrin endocytosis via CIN85/Ruk(L)-mediated ubiquitination. We can demonstrate that the loss of nephrin expression and onset of the proteinuria in CD2AP(-/-) mice correlates with an increased accumulation of ubiquitinated proteins and expression of CIN85/Ruk(L) in podocy...
|
PMID: 20457601
PDF is available here.
PDF is available here.
Abstract
A proteomic approach was used to investigate the dynamic cellular host cell response induced by influenza virus infection in two different vaccine production cell lines, MDCK and Vero. For identification of proteins possibly involved in global host cell response mechanisms and virus-host cell intera...
|
PMID: 20435171
PDF is available here.
PDF is available here.
FEMS Microbiology Letters (309)1 2010
Abstract
We have characterized a DeltarodZ mutant and show that defective peptidoglycan synthesis might be the primary effect of the deletion. A motile pseudorevertant of DeltarodZ isolated possessed a near rod-shaped cell morphology, indicating that RodZ is not absolutely required for the elongation of the...
|
PMID: 20528937
PDF is available here.
PDF is available here.
Infection and Immunity (78)8 2010
Abstract
We examine the organization of clathrin in pedestals and report that CD2AP, an endocytosis-associated and cortactin-binding protein, is a novel and important component of EPEC pedestal formation that also utilizes Y474 phosphorylation of EPEC Tir. We also demonstrate the successive recruitment of Nc...
|
PMID: 20515931
PDF is available here.
PDF is available here.
Molecular Cell (39)2 2010
Abstract
We have now determined the structure of an Hsp90-CS-CHORD ternary complex, providing a framework for understanding the dynamic nature of Hsp90-Rar1-Sgt1 complexes. Mutational and biochemical analyses define the architecture of the ternary complex that recruits nucleotide-binding leucine-rich repeat...
|
PMID: 20670895
PDF is available here.
PDF is available here.
Histopathology (57)2 2010
Abstract
We aimed to analyse the expression of smoothelin in the gastrointestinal tract in MP and MM in order to define a novel diagnostic tool to identify MM bundles.
The expression of smoothelin was analysed immunohistochemically in comparison with alpha-smooth muscle actin (alpha-SMA) in specimens from co...
|
PMID: 20716166
PDF is available here.
PDF is available here.
Abstract
We found that ciliary membrane proteins were highly mobile, but their diffusion was impeded at the base of the cilium by a diffusion barrier. Septin 2 (SEPT2), a member of the septin family of guanosine triphosphatases that form a diffusion barrier in budding yeast, localized at the base of the cili...
|
PMID: 20558667
PDF is available here.
PDF is available here.
A surveillance pathway monitors the fitness of the endoplasmic reticulum to control its inheritance.
Abstract
We report here that ER stress in S. cerevisiae activates the MAP kinase Slt2 in a new ER stress surveillance (ERSU) pathway, independent of the unfolded protein response. Upon ER stress, ERSU alters the septin complex to delay ER inheritance and cytokinesis. In the absence of Slt2 kinase, the stress...
|
PMID: 20619447
PDF is available here.
PDF is available here.
Journal of Biological Chemistry (285)29 2010
Abstract
We have characterized the functional motions in FtsZ with a computational consensus of essential dynamics, structural comparisons, sequence conservation, and networks of co-evolving residues. Employing this information, we have constructed 17 mutants, which alter the FtsZ functional cycle at differe...
|
PMID: 20472561
PDF is available here.
PDF is available here.
Abstract
A decrease in environmental temperature can directly affect the contractility of cutaneous vasculature, mediated in part by alpha(2)-adrenoceptors. Most of the cellular mechanisms underlying the cooling-enhanced contractility to alpha(2)-adrenoceptor agonists have been reported in cu...
|
PMID: 20360439
PDF is available here.
PDF is available here.
Abstract
We show that LMP1 is upregulated in early stage of PDL cell osteogenic differentiation. Stable gene knockdown of LMP1 by shRNA inhibits DNA synthesis and corresponding cell proliferation in PDL cells, and further leads to decreased mineralization in vitro. Overexpression of LMP1 increases cell proli...
|
PMID: 20348040
PDF is available here.
PDF is available here.
Molecular Pharmacology (78)1 2010
Abstract
We reported previously that ethanol treatment regulates D(1) receptor phosphorylation and signaling in a protein kinase C (PKC) delta- and PKCgamma-dependent fashion by a mechanism that may involve PKC isozyme-specific interacting proteins. Using a PKC isozyme-specific coimmunoprecipitation approach...
|
PMID: 20395553
PDF is available here.
PDF is available here.
Molecular Pharmacology (78)1 2010
Abstract
We reported previously that ethanol treatment regulates D(1) receptor phosphorylation and signaling in a protein kinase C (PKC) delta- and PKCgamma-dependent fashion by a mechanism that may involve PKC isozyme-specific interacting proteins. Using a PKC isozyme-specific coimmunoprecipitation approach...
|
PMID: 20395553
PDF is available here.
PDF is available here.
Molecular Pharmacology (78)1 2010
Abstract
We reported previously that ethanol treatment regulates D(1) receptor phosphorylation and signaling in a protein kinase C (PKC) delta- and PKCgamma-dependent fashion by a mechanism that may involve PKC isozyme-specific interacting proteins. Using a PKC isozyme-specific coimmunoprecipitation approach...
|
PMID: 20395553
PDF is available here.
PDF is available here.
Molecular Pharmacology (78)1 2010
Abstract
We reported previously that ethanol treatment regulates D(1) receptor phosphorylation and signaling in a protein kinase C (PKC) delta- and PKCgamma-dependent fashion by a mechanism that may involve PKC isozyme-specific interacting proteins. Using a PKC isozyme-specific coimmunoprecipitation approach...
|
PMID: 20395553
PDF is available here.
PDF is available here.
Molecular Pharmacology (78)1 2010
Abstract
We reported previously that ethanol treatment regulates D(1) receptor phosphorylation and signaling in a protein kinase C (PKC) delta- and PKCgamma-dependent fashion by a mechanism that may involve PKC isozyme-specific interacting proteins. Using a PKC isozyme-specific coimmunoprecipitation approach...
|
PMID: 20395553
PDF is available here.
PDF is available here.
Molecular Pharmacology (78)1 2010
Abstract
We reported previously that ethanol treatment regulates D(1) receptor phosphorylation and signaling in a protein kinase C (PKC) delta- and PKCgamma-dependent fashion by a mechanism that may involve PKC isozyme-specific interacting proteins. Using a PKC isozyme-specific coimmunoprecipitation approach...
|
PMID: 20395553
PDF is available here.
PDF is available here.
Molecular Pharmacology (78)1 2010
Abstract
We reported previously that ethanol treatment regulates D(1) receptor phosphorylation and signaling in a protein kinase C (PKC) delta- and PKCgamma-dependent fashion by a mechanism that may involve PKC isozyme-specific interacting proteins. Using a PKC isozyme-specific coimmunoprecipitation approach...
|
PMID: 20395553
PDF is available here.
PDF is available here.
Molecular Pharmacology (78)1 2010
Abstract
We reported previously that ethanol treatment regulates D(1) receptor phosphorylation and signaling in a protein kinase C (PKC) delta- and PKCgamma-dependent fashion by a mechanism that may involve PKC isozyme-specific interacting proteins. Using a PKC isozyme-specific coimmunoprecipitation approach...
|
PMID: 20395553
PDF is available here.
PDF is available here.
Molecular Pharmacology (78)1 2010
Abstract
We reported previously that ethanol treatment regulates D(1) receptor phosphorylation and signaling in a protein kinase C (PKC) delta- and PKCgamma-dependent fashion by a mechanism that may involve PKC isozyme-specific interacting proteins. Using a PKC isozyme-specific coimmunoprecipitation approach...
|
PMID: 20395553
PDF is available here.
PDF is available here.
Molecular Pharmacology (78)1 2010
Abstract
We reported previously that ethanol treatment regulates D(1) receptor phosphorylation and signaling in a protein kinase C (PKC) delta- and PKCgamma-dependent fashion by a mechanism that may involve PKC isozyme-specific interacting proteins. Using a PKC isozyme-specific coimmunoprecipitation approach...
|
PMID: 20395553
PDF is available here.
PDF is available here.
Molecular Pharmacology (78)1 2010
Abstract
We reported previously that ethanol treatment regulates D(1) receptor phosphorylation and signaling in a protein kinase C (PKC) delta- and PKCgamma-dependent fashion by a mechanism that may involve PKC isozyme-specific interacting proteins. Using a PKC isozyme-specific coimmunoprecipitation approach...
|
PMID: 20395553
PDF is available here.
PDF is available here.
Molecular Pharmacology (78)1 2010
Abstract
We reported previously that ethanol treatment regulates D(1) receptor phosphorylation and signaling in a protein kinase C (PKC) delta- and PKCgamma-dependent fashion by a mechanism that may involve PKC isozyme-specific interacting proteins. Using a PKC isozyme-specific coimmunoprecipitation approach...
|
PMID: 20395553
PDF is available here.
PDF is available here.
Molecular Pharmacology (78)1 2010
Abstract
We reported previously that ethanol treatment regulates D(1) receptor phosphorylation and signaling in a protein kinase C (PKC) delta- and PKCgamma-dependent fashion by a mechanism that may involve PKC isozyme-specific interacting proteins. Using a PKC isozyme-specific coimmunoprecipitation approach...
|
PMID: 20395553
PDF is available here.
PDF is available here.
Molecular Pharmacology (78)1 2010
Abstract
We reported previously that ethanol treatment regulates D(1) receptor phosphorylation and signaling in a protein kinase C (PKC) delta- and PKCgamma-dependent fashion by a mechanism that may involve PKC isozyme-specific interacting proteins. Using a PKC isozyme-specific coimmunoprecipitation approach...
|
PMID: 20395553
PDF is available here.
PDF is available here.
Molecular Pharmacology (78)1 2010
Abstract
We reported previously that ethanol treatment regulates D(1) receptor phosphorylation and signaling in a protein kinase C (PKC) delta- and PKCgamma-dependent fashion by a mechanism that may involve PKC isozyme-specific interacting proteins. Using a PKC isozyme-specific coimmunoprecipitation approach...
|
PMID: 20395553
PDF is available here.
PDF is available here.
Molecular Pharmacology (78)1 2010
Abstract
We reported previously that ethanol treatment regulates D(1) receptor phosphorylation and signaling in a protein kinase C (PKC) delta- and PKCgamma-dependent fashion by a mechanism that may involve PKC isozyme-specific interacting proteins. Using a PKC isozyme-specific coimmunoprecipitation approach...
|
PMID: 20395553
PDF is available here.
PDF is available here.
Molecular Pharmacology (78)1 2010
Abstract
We reported previously that ethanol treatment regulates D(1) receptor phosphorylation and signaling in a protein kinase C (PKC) delta- and PKCgamma-dependent fashion by a mechanism that may involve PKC isozyme-specific interacting proteins. Using a PKC isozyme-specific coimmunoprecipitation approach...
|
PMID: 20395553
PDF is available here.
PDF is available here.
Molecular Pharmacology (78)1 2010
Abstract
We reported previously that ethanol treatment regulates D(1) receptor phosphorylation and signaling in a protein kinase C (PKC) delta- and PKCgamma-dependent fashion by a mechanism that may involve PKC isozyme-specific interacting proteins. Using a PKC isozyme-specific coimmunoprecipitation approach...
|
PMID: 20395553
PDF is available here.
PDF is available here.
Molecular Pharmacology (78)1 2010
Abstract
We reported previously that ethanol treatment regulates D(1) receptor phosphorylation and signaling in a protein kinase C (PKC) delta- and PKCgamma-dependent fashion by a mechanism that may involve PKC isozyme-specific interacting proteins. Using a PKC isozyme-specific coimmunoprecipitation approach...
|
PMID: 20395553
PDF is available here.
PDF is available here.
Molecular Pharmacology (78)1 2010
Abstract
We reported previously that ethanol treatment regulates D(1) receptor phosphorylation and signaling in a protein kinase C (PKC) delta- and PKCgamma-dependent fashion by a mechanism that may involve PKC isozyme-specific interacting proteins. Using a PKC isozyme-specific coimmunoprecipitation approach...
|
PMID: 20395553
PDF is available here.
PDF is available here.
Molecular Pharmacology (78)1 2010
Abstract
We reported previously that ethanol treatment regulates D(1) receptor phosphorylation and signaling in a protein kinase C (PKC) delta- and PKCgamma-dependent fashion by a mechanism that may involve PKC isozyme-specific interacting proteins. Using a PKC isozyme-specific coimmunoprecipitation approach...
|
PMID: 20395553
PDF is available here.
PDF is available here.
Molecular Pharmacology (78)1 2010
Abstract
We reported previously that ethanol treatment regulates D(1) receptor phosphorylation and signaling in a protein kinase C (PKC) delta- and PKCgamma-dependent fashion by a mechanism that may involve PKC isozyme-specific interacting proteins. Using a PKC isozyme-specific coimmunoprecipitation approach...
|
PMID: 20395553
PDF is available here.
PDF is available here.
Molecular Pharmacology (78)1 2010
Abstract
We reported previously that ethanol treatment regulates D(1) receptor phosphorylation and signaling in a protein kinase C (PKC) delta- and PKCgamma-dependent fashion by a mechanism that may involve PKC isozyme-specific interacting proteins. Using a PKC isozyme-specific coimmunoprecipitation approach...
|
PMID: 20395553
PDF is available here.
PDF is available here.
Molecular Pharmacology (78)1 2010
Abstract
We reported previously that ethanol treatment regulates D(1) receptor phosphorylation and signaling in a protein kinase C (PKC) delta- and PKCgamma-dependent fashion by a mechanism that may involve PKC isozyme-specific interacting proteins. Using a PKC isozyme-specific coimmunoprecipitation approach...
|
PMID: 20395553
PDF is available here.
PDF is available here.