Abstract
We describe the use of computer-controllable suspension bioreactors to form EBs in an automated and highly reproducible process and their subsequent differentiation along the osteoblast lineage. The development of the differentiating cells taken from bioreactor EBs to EBs formed in static control cu...
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PMID: 21042990
PDF is available here.
Abstract
We studied the temporal generation and diversity of Neurog2-positive precursor progeny using an inducible genetic fate mapping approach. We show that all subtypes of glutamatergic neurons derive from Neurog2 positive progenitors during development of the OB. Projection neurons, that is, mitral and t...
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PMID: 21466690
PDF is available here.
Abstract
We examined piebald, a pigmentation phenotype in both human and Merino sheep, by analysing multiple data types using a systems approach. First, a case control analysis of 49,034 ovine SNP was performed which confirmed a multigenic basis for the condition. We combined these results with gene expressi...
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PMID: 21701676
PDF is available here.
Abstract
We identify in the mouse a subpopulation of the first (crescent-forming) field marked by endothelin receptor type A (Ednra) gene expression, which contributes to chamber myocardium through a unique type of cell behavior. Ednra-lacZ/EGFP-expressing cells arise in the ventrocaudal inflow region of the...
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PMID: 20929948
PDF is available here.
Wendy S Garrett,
Carey A Gallini,
Tanya Yatsunenko,
Monia Michaud,
Andrea DuBois,
Mary L Delaney,
Shivesh Punit,
Maria Karlsson,
Lynn Bry,
Jonathan N Glickman,
Jeffrey I Gordon,
Andrew B Onderdonk and
Laurie H Glimcher
Abstract
We characterized the fecal microbial communities in the recently described T-bet(-/-) ×Rag2(-/-) ulcerative colitis (TRUC) model driven by T-bet deficiency in the innate immune system. 16S rRNA-based analysis of TRUC and Rag2(-/-) mice revealed distinctive communities that correlate with host genot...
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PMID: 20833380
PDF is available here.
Abstract
We showed that TCF-1 deficiency limited proliferation of CD8(+) effector T cells and impaired their differentiation toward a central memory phenotype. Moreover, TCF-1-deficient memory CD8(+) T cells were progressively lost over time, exhibiting reduced expression of the antiapoptotic molecule Bcl-2...
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PMID: 20727791
PDF is available here.
Abstract
We have now examined the role of GPx1 in the activation, differentiation, and functions of CD4(+) T helper (Th) cells. TCR stimulation increased the intracellular ROS concentration in Th cells in a time-dependent manner, and such TCR-induced ROS generation was found to promote cell proliferation. GP...
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PMID: 20367278
PDF is available here.
Abstract
We show that Tbr2-positive cortical intermediate (basal) neuronal progenitors (INPs) dictate the migratory route and control the amount of subpallial GABAergic interneurons in the subventricular zone (SVZ) through a non-cell-autonomous mechanism. In fact, Tbr2 interneuron attractive activity is mode...
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PMID: 20713522
PDF is available here.
Abstract
We report that a combination of three developmental transcription factors (i.e., Gata4, Mef2c, and Tbx5) rapidly and efficiently reprogrammed postnatal cardiac or dermal fibroblasts directly into differentiated cardiomyocyte-like cells. Induced cardiomyocytes expressed cardiac-specific markers, had...
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PMID: 20691899
PDF is available here.
Abstract
We aim to identify the signaling molecules and transcription factors that regulate PE specification.
Here, we present the first genetic evidence that bone morphogenetic protein (Bmp) signaling in conjunction with the T-box transcription factor Tbx5a is essential for PE specification...
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PMID: 20413782
PDF is available here.
Abstract
We aim to identify the signaling molecules and transcription factors that regulate PE specification.
Here, we present the first genetic evidence that bone morphogenetic protein (Bmp) signaling in conjunction with the T-box transcription factor Tbx5a is essential for PE specification...
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PMID: 20413782
PDF is available here.
Abstract
We aim to identify the signaling molecules and transcription factors that regulate PE specification.
Here, we present the first genetic evidence that bone morphogenetic protein (Bmp) signaling in conjunction with the T-box transcription factor Tbx5a is essential for PE specification...
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PMID: 20413782
PDF is available here.
Abstract
We aim to identify the signaling molecules and transcription factors that regulate PE specification.
Here, we present the first genetic evidence that bone morphogenetic protein (Bmp) signaling in conjunction with the T-box transcription factor Tbx5a is essential for PE specification...
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PMID: 20413782
PDF is available here.
Abstract
We aim to identify the signaling molecules and transcription factors that regulate PE specification.
Here, we present the first genetic evidence that bone morphogenetic protein (Bmp) signaling in conjunction with the T-box transcription factor Tbx5a is essential for PE specification...
|
PMID: 20413782
PDF is available here.
Abstract
We aim to identify the signaling molecules and transcription factors that regulate PE specification.
Here, we present the first genetic evidence that bone morphogenetic protein (Bmp) signaling in conjunction with the T-box transcription factor Tbx5a is essential for PE specification...
|
PMID: 20413782
PDF is available here.
Abstract
We aim to identify the signaling molecules and transcription factors that regulate PE specification.
Here, we present the first genetic evidence that bone morphogenetic protein (Bmp) signaling in conjunction with the T-box transcription factor Tbx5a is essential for PE specification...
|
PMID: 20413782
PDF is available here.
Abstract
We aim to identify the signaling molecules and transcription factors that regulate PE specification.
Here, we present the first genetic evidence that bone morphogenetic protein (Bmp) signaling in conjunction with the T-box transcription factor Tbx5a is essential for PE specification...
|
PMID: 20413782
PDF is available here.
Abstract
We aim to identify the signaling molecules and transcription factors that regulate PE specification.
Here, we present the first genetic evidence that bone morphogenetic protein (Bmp) signaling in conjunction with the T-box transcription factor Tbx5a is essential for PE specification...
|
PMID: 20413782
PDF is available here.
Abstract
We aim to identify the signaling molecules and transcription factors that regulate PE specification.
Here, we present the first genetic evidence that bone morphogenetic protein (Bmp) signaling in conjunction with the T-box transcription factor Tbx5a is essential for PE specification...
|
PMID: 20413782
PDF is available here.
Abstract
We aim to identify the signaling molecules and transcription factors that regulate PE specification.
Here, we present the first genetic evidence that bone morphogenetic protein (Bmp) signaling in conjunction with the T-box transcription factor Tbx5a is essential for PE specification...
|
PMID: 20413782
PDF is available here.
Abstract
We aim to identify the signaling molecules and transcription factors that regulate PE specification.
Here, we present the first genetic evidence that bone morphogenetic protein (Bmp) signaling in conjunction with the T-box transcription factor Tbx5a is essential for PE specification...
|
PMID: 20413782
PDF is available here.
Abstract
We aim to identify the signaling molecules and transcription factors that regulate PE specification.
Here, we present the first genetic evidence that bone morphogenetic protein (Bmp) signaling in conjunction with the T-box transcription factor Tbx5a is essential for PE specification...
|
PMID: 20413782
PDF is available here.
Abstract
We aim to identify the signaling molecules and transcription factors that regulate PE specification.
Here, we present the first genetic evidence that bone morphogenetic protein (Bmp) signaling in conjunction with the T-box transcription factor Tbx5a is essential for PE specification...
|
PMID: 20413782
PDF is available here.
Abstract
We aim to identify the signaling molecules and transcription factors that regulate PE specification.
Here, we present the first genetic evidence that bone morphogenetic protein (Bmp) signaling in conjunction with the T-box transcription factor Tbx5a is essential for PE specification...
|
PMID: 20413782
PDF is available here.
Abstract
We aim to identify the signaling molecules and transcription factors that regulate PE specification.
Here, we present the first genetic evidence that bone morphogenetic protein (Bmp) signaling in conjunction with the T-box transcription factor Tbx5a is essential for PE specification...
|
PMID: 20413782
PDF is available here.
Abstract
We aim to identify the signaling molecules and transcription factors that regulate PE specification.
Here, we present the first genetic evidence that bone morphogenetic protein (Bmp) signaling in conjunction with the T-box transcription factor Tbx5a is essential for PE specification...
|
PMID: 20413782
PDF is available here.
Abstract
We aim to identify the signaling molecules and transcription factors that regulate PE specification.
Here, we present the first genetic evidence that bone morphogenetic protein (Bmp) signaling in conjunction with the T-box transcription factor Tbx5a is essential for PE specification...
|
PMID: 20413782
PDF is available here.
Abstract
We aim to identify the signaling molecules and transcription factors that regulate PE specification.
Here, we present the first genetic evidence that bone morphogenetic protein (Bmp) signaling in conjunction with the T-box transcription factor Tbx5a is essential for PE specification...
|
PMID: 20413782
PDF is available here.
Abstract
We aim to identify the signaling molecules and transcription factors that regulate PE specification.
Here, we present the first genetic evidence that bone morphogenetic protein (Bmp) signaling in conjunction with the T-box transcription factor Tbx5a is essential for PE specification...
|
PMID: 20413782
PDF is available here.
Abstract
We aim to identify the signaling molecules and transcription factors that regulate PE specification.
Here, we present the first genetic evidence that bone morphogenetic protein (Bmp) signaling in conjunction with the T-box transcription factor Tbx5a is essential for PE specification...
|
PMID: 20413782
PDF is available here.
Abstract
We aim to identify the signaling molecules and transcription factors that regulate PE specification.
Here, we present the first genetic evidence that bone morphogenetic protein (Bmp) signaling in conjunction with the T-box transcription factor Tbx5a is essential for PE specification...
|
PMID: 20413782
PDF is available here.
Abstract
We aim to identify the signaling molecules and transcription factors that regulate PE specification.
Here, we present the first genetic evidence that bone morphogenetic protein (Bmp) signaling in conjunction with the T-box transcription factor Tbx5a is essential for PE specification...
|
PMID: 20413782
PDF is available here.
Abstract
We aim to identify the signaling molecules and transcription factors that regulate PE specification.
Here, we present the first genetic evidence that bone morphogenetic protein (Bmp) signaling in conjunction with the T-box transcription factor Tbx5a is essential for PE specification...
|
PMID: 20413782
PDF is available here.