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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Vesicular Transport Proteins (10):
Recent article
Vesicular Transport Proteins
Eukaryotic Cell (10)9 2011
Abstract
We analyzed the structure of the macronuclear TtVPS13A gene, which was found to be composed of 17 exons spanning 12.5 kb and was predicted to encode a protein of 3,475 amino acids (aa). A strain expressing a TtVPS13A-green fluorescent protein (GFP) fusion protein was constructed, and the protein was...
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PMID: 21764909
PDF is available here.
PDF is available here.
| < More recent | Older article > |
Developmental Cell (21)2 2011
Abstract
We show that selective autophagy downregulates Ty1 transposition by eliminating Ty1 VLPs from the cytoplasm under nutrient-limited conditions. Ty1 VLPs are targeted to autophagosomes by an interaction with Atg19. We propose that selective autophagy safeguards genome integrity against excessive inser...
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PMID: 21839922
PDF is available here.
PDF is available here.
Abstract
We showed that the t(4;9)(q21;p24) leads to a novel SEC31A-JAK2 fusion. Screening of 131 cHL cases identified 1 additional case with SEC31A-JAK2 and 2 additional cases with rearrangements involving JAK2. We demonstrated that SEC31A-JAK2 is oncogenic in vitro and acts as a constitutively activated ty...
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PMID: 21325169
PDF is available here.
PDF is available here.
Abstract
We found that for responses measured above 0.2%, inter-laboratory %CVs were, on average, 35%. No differences in inter-laboratory variation were observed if a 4-color antibody cocktail or a 7-color combination was used. Moreover, the data allowed identification of important sources of variability for...
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PMID: 20727897
PDF is available here.
PDF is available here.
EMBO Journal (30)18 2011
Abstract
We found that ERK7 negatively regulates secretion in response to serum and amino-acid starvation, in both Drosophila and human cells. Under these conditions, ERK7 turnover through the proteasome is inhibited, and the resulting higher levels of this kinase lead to a modification in a site within the...
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PMID: 21847093
PDF is available here.
PDF is available here.
Abstract
We report that BEC-1, the C. elegans ortholog of Atg6/Vps30/Beclin1, a key regulator of the autophagic machinery, also contributes to endosome function. In particular we identify a defect in retrograde transport from endosomes to the Golgi in bec-1 mutants. MIG-14/Wntless is normally recycled from e...
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PMID: 21183797
PDF is available here.
PDF is available here.
Abstract
We generated Vps26b knockout mice and studied their molecular, histological, and behavioral phenotypes. We found that the loss of Vps26b results in no significant defects in the behavior, body size, and health of the mice. Vps26b-deficient mice showed a severe reduction of Vps35 protein at cellular...
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PMID: 21040701
PDF is available here.
PDF is available here.
Abstract
We investigated distinct genetic profiles in Korean PTC through cDNA microarray analysis.
Transcriptional profiles of five PTC samples and five paired normal thyroid tissue samples were generated using cDNA microarrays. The tumors were genotyped for BRAF mutations. The results of the cDNA microarray...
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PMID: 21179278
PDF is available here.
PDF is available here.
Abstract
We examined 75 vascular lesions: KHE (n=18), TA (n=13), infantile hemangioma (n=13), pyogenic granuloma (n=18), and granulation tissue (n=13). Overall, KHE and TA shared an identical endothelial immunophenotype: the neoplastic spindle cells were Prox1, podoplanin, LYVE-1, CD31, and CD34, whereas end...
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PMID: 20975337
PDF is available here.
PDF is available here.
Free Radical Research (44)11 2010
Abstract
Nrf2, a redox sensitive transcription factor, plays a pivotal role in redox homeostasis during oxidative stress. Nrf2 is sequestered in cytosol by an inhibitory protein Keap1 which causes its proteasomal degradation. In response to electrophilic and oxidative stress, Nrf2 is activated, translocates...
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PMID: 20815789
PDF is available here.
PDF is available here.
Abstract
We performed a phenotype-driven high throughput screening with a random siRNA library, in search of novel genes that can accelerate murine preosteoblast MC3T3-E1 cell proliferation. Three siRNAs screened from the library were able to enhance MC3T3-E1 cell proliferation significantly. One of the prol...
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PMID: 20712584
PDF is available here.
PDF is available here.
Abstract
We use Drosophila melanogaster to identify the Rab11/Sec15 exocyst, which acts at the last step of endocytic recycling, as a novel target of both EF and LF. EF reduces levels of apically localized Rab11 and indirectly blocks vesicle formation by its binding partner and effector Sec15 (Sec15-GFP), wh...
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PMID: 20944747
PDF is available here.
PDF is available here.
Lymphology (43)3 2010
Abstract
This study investigated (cardiac) remodeling of the myocardial microvasculature in patients with terminal heart failure due to ischemic (ICM) and dilative (DCM) cardiomyopathy. Seventeen transmural left-ventricular (LV) biopsies (9 ICM and 8 DCM), taken from heart transplant recipients at transplant...
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PMID: 21226413
PDF is available here.
PDF is available here.
Abstract
We did not recognize correlations of LYVE-1/+ vessel density to the distribution of the myofibre spectrum in trained skeletal muscle.
It was concluded that lymphatic vessels are rather normally distributed in skeletal muscle not dependent on a predominant myofibre type. The partial n...
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PMID: 20863269
PDF is available here.
PDF is available here.
Biophysical Journal (99)4 2010
Abstract
We implement sensitized emission Förster resonance energy transfer (FRET) stoichiometry under total internal reflection fluorescence (TIRF) microscopy. We demonstrate through quantitative analysis and modeling that evanescent fields must be precisely matched between FRET excitation wavelengths to i...
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PMID: 20713017
PDF is available here.
PDF is available here.
Abstract
Cohen syndrome is a rare autosomal recessive inherited disorder that results from mutations of the VPS13B gene. Clinical features consist of a combination of mental retardation, facial dysmorphism, postnatal microcephaly, truncal obesity, slender extremities, joint hyperextensibility, myopia, progre...
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PMID: 20656880
PDF is available here.
PDF is available here.
Abstract
Mutations in SOD1, ANG, VAPB, TARDBP and FUS genes have been identified in amyotrophic lateral sclerosis (ALS).
The relative contributions of the different mutations to ALS were estimated by systematically screening a cohort of 162 families enrolled in France and 500 controls (1000 chromosomes) usin...
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PMID: 20577002
PDF is available here.
PDF is available here.
Abstract
We discuss integrated structural studies of proteins whose assembly shapes membranes into vesicles and tubules, before turning to the so-called tethering factors that appear to orchestrate vesicle docking and fusion.
Copyright 2010 Elsevier Ltd. All rights reserved....
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PMID: 20418086
PDF is available here.
PDF is available here.
Abstract
We immunolocalized lymphatic and vascular blood vessels in 12- and 14-week-old human fetal knee joint tissues using a polyclonal antibody to a lymphatic vascular endothelium specific hyaluronan receptor (LYVE-1) and a monoclonal antibody to podoplanin (mAb D2-40). A number of lymphatic vessels were...
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PMID: 20334573
PDF is available here.
PDF is available here.
Journal of Cell Science (123)Pt 14 2010
Abstract
We report Drosophila Waharan (Wah), a 170-kD predominantly nuclear protein with two potential human homologues, as a newly identified regulator of endosomal trafficking. Wah is required for neuromuscular-junction development and muscle integrity. In muscles, knockdown of Wah caused novel accumulatio...
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PMID: 20551180
PDF is available here.
PDF is available here.
New Phytologist (188)2 2010
Abstract
We used the Arabidopsis seed coat to study the participation of the exocyst complex in polarized pectin delivery. • We characterized the amount of pectinaceous mucilage and seed coat structure in sec8 and exo70A1 exocyst mutants. Using a yeast two-hybrid screen, we identified a new interactor of t...
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PMID: 20618910
PDF is available here.
PDF is available here.
Human Mutation (31)7 2010
Abstract
We report a resequencing array that allows the simultaneous resequencing of up to 92 genes associated with IMDs. To validate the array, DNA samples from 51 patients with 52 different known variants (including point variants, small insertion, and deletions [indels]) in seven genes (C14ORF133, GAA, NP...
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PMID: 20578233
PDF is available here.
PDF is available here.
Human Mutation (31)7 2010
Abstract
We report a resequencing array that allows the simultaneous resequencing of up to 92 genes associated with IMDs. To validate the array, DNA samples from 51 patients with 52 different known variants (including point variants, small insertion, and deletions [indels]) in seven genes (C14ORF133, GAA, NP...
|
PMID: 20578233
PDF is available here.
PDF is available here.
Human Mutation (31)7 2010
Abstract
We report a resequencing array that allows the simultaneous resequencing of up to 92 genes associated with IMDs. To validate the array, DNA samples from 51 patients with 52 different known variants (including point variants, small insertion, and deletions [indels]) in seven genes (C14ORF133, GAA, NP...
|
PMID: 20578233
PDF is available here.
PDF is available here.
Human Mutation (31)7 2010
Abstract
We report a resequencing array that allows the simultaneous resequencing of up to 92 genes associated with IMDs. To validate the array, DNA samples from 51 patients with 52 different known variants (including point variants, small insertion, and deletions [indels]) in seven genes (C14ORF133, GAA, NP...
|
PMID: 20578233
PDF is available here.
PDF is available here.
Human Mutation (31)7 2010
Abstract
We report a resequencing array that allows the simultaneous resequencing of up to 92 genes associated with IMDs. To validate the array, DNA samples from 51 patients with 52 different known variants (including point variants, small insertion, and deletions [indels]) in seven genes (C14ORF133, GAA, NP...
|
PMID: 20578233
PDF is available here.
PDF is available here.
Human Mutation (31)7 2010
Abstract
We report a resequencing array that allows the simultaneous resequencing of up to 92 genes associated with IMDs. To validate the array, DNA samples from 51 patients with 52 different known variants (including point variants, small insertion, and deletions [indels]) in seven genes (C14ORF133, GAA, NP...
|
PMID: 20578233
PDF is available here.
PDF is available here.
Human Mutation (31)7 2010
Abstract
We report a resequencing array that allows the simultaneous resequencing of up to 92 genes associated with IMDs. To validate the array, DNA samples from 51 patients with 52 different known variants (including point variants, small insertion, and deletions [indels]) in seven genes (C14ORF133, GAA, NP...
|
PMID: 20578233
PDF is available here.
PDF is available here.
Human Mutation (31)7 2010
Abstract
We report a resequencing array that allows the simultaneous resequencing of up to 92 genes associated with IMDs. To validate the array, DNA samples from 51 patients with 52 different known variants (including point variants, small insertion, and deletions [indels]) in seven genes (C14ORF133, GAA, NP...
|
PMID: 20578233
PDF is available here.
PDF is available here.
Human Mutation (31)7 2010
Abstract
We report a resequencing array that allows the simultaneous resequencing of up to 92 genes associated with IMDs. To validate the array, DNA samples from 51 patients with 52 different known variants (including point variants, small insertion, and deletions [indels]) in seven genes (C14ORF133, GAA, NP...
|
PMID: 20578233
PDF is available here.
PDF is available here.
Human Mutation (31)7 2010
Abstract
We report a resequencing array that allows the simultaneous resequencing of up to 92 genes associated with IMDs. To validate the array, DNA samples from 51 patients with 52 different known variants (including point variants, small insertion, and deletions [indels]) in seven genes (C14ORF133, GAA, NP...
|
PMID: 20578233
PDF is available here.
PDF is available here.
Human Mutation (31)7 2010
Abstract
We report a resequencing array that allows the simultaneous resequencing of up to 92 genes associated with IMDs. To validate the array, DNA samples from 51 patients with 52 different known variants (including point variants, small insertion, and deletions [indels]) in seven genes (C14ORF133, GAA, NP...
|
PMID: 20578233
PDF is available here.
PDF is available here.
Human Mutation (31)7 2010
Abstract
We report a resequencing array that allows the simultaneous resequencing of up to 92 genes associated with IMDs. To validate the array, DNA samples from 51 patients with 52 different known variants (including point variants, small insertion, and deletions [indels]) in seven genes (C14ORF133, GAA, NP...
|
PMID: 20578233
PDF is available here.
PDF is available here.
Human Mutation (31)7 2010
Abstract
We report a resequencing array that allows the simultaneous resequencing of up to 92 genes associated with IMDs. To validate the array, DNA samples from 51 patients with 52 different known variants (including point variants, small insertion, and deletions [indels]) in seven genes (C14ORF133, GAA, NP...
|
PMID: 20578233
PDF is available here.
PDF is available here.
Human Mutation (31)7 2010
Abstract
We report a resequencing array that allows the simultaneous resequencing of up to 92 genes associated with IMDs. To validate the array, DNA samples from 51 patients with 52 different known variants (including point variants, small insertion, and deletions [indels]) in seven genes (C14ORF133, GAA, NP...
|
PMID: 20578233
PDF is available here.
PDF is available here.
Human Mutation (31)7 2010
Abstract
We report a resequencing array that allows the simultaneous resequencing of up to 92 genes associated with IMDs. To validate the array, DNA samples from 51 patients with 52 different known variants (including point variants, small insertion, and deletions [indels]) in seven genes (C14ORF133, GAA, NP...
|
PMID: 20578233
PDF is available here.
PDF is available here.
Human Mutation (31)7 2010
Abstract
We report a resequencing array that allows the simultaneous resequencing of up to 92 genes associated with IMDs. To validate the array, DNA samples from 51 patients with 52 different known variants (including point variants, small insertion, and deletions [indels]) in seven genes (C14ORF133, GAA, NP...
|
PMID: 20578233
PDF is available here.
PDF is available here.
Human Mutation (31)7 2010
Abstract
We report a resequencing array that allows the simultaneous resequencing of up to 92 genes associated with IMDs. To validate the array, DNA samples from 51 patients with 52 different known variants (including point variants, small insertion, and deletions [indels]) in seven genes (C14ORF133, GAA, NP...
|
PMID: 20578233
PDF is available here.
PDF is available here.
Human Mutation (31)7 2010
Abstract
We report a resequencing array that allows the simultaneous resequencing of up to 92 genes associated with IMDs. To validate the array, DNA samples from 51 patients with 52 different known variants (including point variants, small insertion, and deletions [indels]) in seven genes (C14ORF133, GAA, NP...
|
PMID: 20578233
PDF is available here.
PDF is available here.
Human Mutation (31)7 2010
Abstract
We report a resequencing array that allows the simultaneous resequencing of up to 92 genes associated with IMDs. To validate the array, DNA samples from 51 patients with 52 different known variants (including point variants, small insertion, and deletions [indels]) in seven genes (C14ORF133, GAA, NP...
|
PMID: 20578233
PDF is available here.
PDF is available here.
Human Mutation (31)7 2010
Abstract
We report a resequencing array that allows the simultaneous resequencing of up to 92 genes associated with IMDs. To validate the array, DNA samples from 51 patients with 52 different known variants (including point variants, small insertion, and deletions [indels]) in seven genes (C14ORF133, GAA, NP...
|
PMID: 20578233
PDF is available here.
PDF is available here.
Human Mutation (31)7 2010
Abstract
We report a resequencing array that allows the simultaneous resequencing of up to 92 genes associated with IMDs. To validate the array, DNA samples from 51 patients with 52 different known variants (including point variants, small insertion, and deletions [indels]) in seven genes (C14ORF133, GAA, NP...
|
PMID: 20578233
PDF is available here.
PDF is available here.
Human Mutation (31)7 2010
Abstract
We report a resequencing array that allows the simultaneous resequencing of up to 92 genes associated with IMDs. To validate the array, DNA samples from 51 patients with 52 different known variants (including point variants, small insertion, and deletions [indels]) in seven genes (C14ORF133, GAA, NP...
|
PMID: 20578233
PDF is available here.
PDF is available here.
Human Mutation (31)7 2010
Abstract
We report a resequencing array that allows the simultaneous resequencing of up to 92 genes associated with IMDs. To validate the array, DNA samples from 51 patients with 52 different known variants (including point variants, small insertion, and deletions [indels]) in seven genes (C14ORF133, GAA, NP...
|
PMID: 20578233
PDF is available here.
PDF is available here.
Human Mutation (31)7 2010
Abstract
We report a resequencing array that allows the simultaneous resequencing of up to 92 genes associated with IMDs. To validate the array, DNA samples from 51 patients with 52 different known variants (including point variants, small insertion, and deletions [indels]) in seven genes (C14ORF133, GAA, NP...
|
PMID: 20578233
PDF is available here.
PDF is available here.
Human Mutation (31)7 2010
Abstract
We report a resequencing array that allows the simultaneous resequencing of up to 92 genes associated with IMDs. To validate the array, DNA samples from 51 patients with 52 different known variants (including point variants, small insertion, and deletions [indels]) in seven genes (C14ORF133, GAA, NP...
|
PMID: 20578233
PDF is available here.
PDF is available here.
Human Mutation (31)7 2010
Abstract
We report a resequencing array that allows the simultaneous resequencing of up to 92 genes associated with IMDs. To validate the array, DNA samples from 51 patients with 52 different known variants (including point variants, small insertion, and deletions [indels]) in seven genes (C14ORF133, GAA, NP...
|
PMID: 20578233
PDF is available here.
PDF is available here.
Human Mutation (31)7 2010
Abstract
We report a resequencing array that allows the simultaneous resequencing of up to 92 genes associated with IMDs. To validate the array, DNA samples from 51 patients with 52 different known variants (including point variants, small insertion, and deletions [indels]) in seven genes (C14ORF133, GAA, NP...
|
PMID: 20578233
PDF is available here.
PDF is available here.
Human Mutation (31)7 2010
Abstract
We report a resequencing array that allows the simultaneous resequencing of up to 92 genes associated with IMDs. To validate the array, DNA samples from 51 patients with 52 different known variants (including point variants, small insertion, and deletions [indels]) in seven genes (C14ORF133, GAA, NP...
|
PMID: 20578233
PDF is available here.
PDF is available here.
Human Mutation (31)7 2010
Abstract
We report a resequencing array that allows the simultaneous resequencing of up to 92 genes associated with IMDs. To validate the array, DNA samples from 51 patients with 52 different known variants (including point variants, small insertion, and deletions [indels]) in seven genes (C14ORF133, GAA, NP...
|
PMID: 20578233
PDF is available here.
PDF is available here.
Human Mutation (31)7 2010
Abstract
We report a resequencing array that allows the simultaneous resequencing of up to 92 genes associated with IMDs. To validate the array, DNA samples from 51 patients with 52 different known variants (including point variants, small insertion, and deletions [indels]) in seven genes (C14ORF133, GAA, NP...
|
PMID: 20578233
PDF is available here.
PDF is available here.
Human Mutation (31)7 2010
Abstract
We report a resequencing array that allows the simultaneous resequencing of up to 92 genes associated with IMDs. To validate the array, DNA samples from 51 patients with 52 different known variants (including point variants, small insertion, and deletions [indels]) in seven genes (C14ORF133, GAA, NP...
|
PMID: 20578233
PDF is available here.
PDF is available here.
Human Mutation (31)7 2010
Abstract
We report a resequencing array that allows the simultaneous resequencing of up to 92 genes associated with IMDs. To validate the array, DNA samples from 51 patients with 52 different known variants (including point variants, small insertion, and deletions [indels]) in seven genes (C14ORF133, GAA, NP...
|
PMID: 20578233
PDF is available here.
PDF is available here.
Human Mutation (31)7 2010
Abstract
We report a resequencing array that allows the simultaneous resequencing of up to 92 genes associated with IMDs. To validate the array, DNA samples from 51 patients with 52 different known variants (including point variants, small insertion, and deletions [indels]) in seven genes (C14ORF133, GAA, NP...
|
PMID: 20578233
PDF is available here.
PDF is available here.
Human Mutation (31)7 2010
Abstract
We report a resequencing array that allows the simultaneous resequencing of up to 92 genes associated with IMDs. To validate the array, DNA samples from 51 patients with 52 different known variants (including point variants, small insertion, and deletions [indels]) in seven genes (C14ORF133, GAA, NP...
|
PMID: 20578233
PDF is available here.
PDF is available here.
Human Mutation (31)7 2010
Abstract
We report a resequencing array that allows the simultaneous resequencing of up to 92 genes associated with IMDs. To validate the array, DNA samples from 51 patients with 52 different known variants (including point variants, small insertion, and deletions [indels]) in seven genes (C14ORF133, GAA, NP...
|
PMID: 20578233
PDF is available here.
PDF is available here.
Human Mutation (31)7 2010
Abstract
We report a resequencing array that allows the simultaneous resequencing of up to 92 genes associated with IMDs. To validate the array, DNA samples from 51 patients with 52 different known variants (including point variants, small insertion, and deletions [indels]) in seven genes (C14ORF133, GAA, NP...
|
PMID: 20578233
PDF is available here.
PDF is available here.
Human Mutation (31)7 2010
Abstract
We report a resequencing array that allows the simultaneous resequencing of up to 92 genes associated with IMDs. To validate the array, DNA samples from 51 patients with 52 different known variants (including point variants, small insertion, and deletions [indels]) in seven genes (C14ORF133, GAA, NP...
|
PMID: 20578233
PDF is available here.
PDF is available here.
Cellular Microbiology (12)7 2010
Abstract
We found significant invasion of Caco-2 cells by EPEC, which, like tubulation, was blocked by pharmacological inhibition of CCPs. Interestingly, however, inhibition of dynamin activity did not prevent tubulation or EPEC invasion, which is in contrast to Salmonella invasion, which requires dynamin ac...
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PMID: 20088948
PDF is available here.
PDF is available here.
Cellular Microbiology (12)7 2010
Abstract
We found significant invasion of Caco-2 cells by EPEC, which, like tubulation, was blocked by pharmacological inhibition of CCPs. Interestingly, however, inhibition of dynamin activity did not prevent tubulation or EPEC invasion, which is in contrast to Salmonella invasion, which requires dynamin ac...
|
PMID: 20088948
PDF is available here.
PDF is available here.