Find your PDFs fast.
Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Chromogranins (3):
Recent article
Chromogranins
Abstract
We investigated the frequency of PGAs and other lesions in all nonconsultation gastric biopsies and resections (1988 to 2008) diagnosed as AMAG. We further selected cases confirmed as AMAG by immunohistochemical identification of the gastric body (negative gastrin) and linear and nodular enterochrom...
|
PMID: 20975338
PDF is available here.
PDF is available here.
| < More recent | Older article > |
Abstract
Abstract
Small cell neuroendocrine carcinoma (SCNEC) of the urinary bladder is a rare but aggressive neoplasm that usually exhibits neuroendocrine differentiation. Here, the authors report a case of SCNEC in an 80-year-old man. The patient had gross hematuria and nodular mass involving the wall of the urinar...
|
PMID: 20594044
PDF is available here.
PDF is available here.
Abstract
A 58-year-old woman presented with a lump on the left side of the neck. Investigations by ultrasound-guided fine needle aspiration, magnetic resonance imaging, and positron emission tomography were all indicative of a diagnosis of a solitary malignant mass with no primary lesion identified. The pati...
|
PMID: 20303047
PDF is available here.
PDF is available here.
Abstract
We have encountered an increasing number of image-guided adrenal mass biopsies in which the differential diagnosis is adrenal cortical lesion versus pheochromocytoma. This distinction is sometimes difficult because of confounding clinical presentations, overlapping morphologies, and some degree of i...
|
PMID: 20154585
PDF is available here.
PDF is available here.
Abstract
Abstract
Acta Cytologica (54)5 Suppl 2010
Abstract
Pheochromocytomas/paragangliomas are rare tumors originating from neuroectodermic cells, which metastasize in only 10% of cases.
A case of cutaneous metastasis of an extramedullary paraganglioma was diagnosed by fine needle aspiration cytology (FNAC). A 39-year-old woman complained of a recently ari...
|
PMID: 21053562
PDF is available here.
PDF is available here.
Abstract
We looked for correlations of AbetaPP-derived molecules in cerebrospinal fluid (CSF) with chromogranin (Cg) derived peptides, representing the regulated secretion. Patients with Alzheimer's disease (AD, N=32), multiple sclerosis (MS, N=50), and healthy controls (N= 70) were enrolled. CSF was analyze...
|
PMID: 20413871
PDF is available here.
PDF is available here.
Endocrine Journal (57)4 2010
Abstract
Secretory granules in endocrine cells selectively store bioactive peptide hormones and amines, which are secreted in a regulated manner upon appropriate stimulation. In addition to bioactive substances, various proteins and lipids characteristic of secretory granules are likely recruited to a restri...
|
PMID: 20203425
PDF is available here.
PDF is available here.
Abstract
OBSERVATION: A 29 year-old-woman presented with a massive painless slow-growing tumor of the right cheek, with a benign aspect on clinical examination. The CT scan with injection, showed a solid-cystic mass, well defined, and partially enhanced. The mass was easily removed with a com...
|
PMID: 19168194
PDF is available here.
PDF is available here.
Abstract
We reported that secretogranin III (SCG3) and myotubularin-related protein 9 (MTMR9) confer susceptibility to the obesity in the Japanese population. Variations in the insulin-induced gene 2 (INSIG2) and in the fat mass and obesity associated (FTO) genes are also associated with the obesity in the J...
|
PMID: 19202896
PDF is available here.
PDF is available here.
Abstract
We found that the presence of ITCs identified by immunohistochemical analysis may predict the persistence of disease but does not show significant overall survival differences. We also identified beta-catenin as a sensitive immunohistochemical marker of primary and metastatic neuroblastoma....
|
PMID: 19095565
PDF is available here.
PDF is available here.
Endocrine Pathology (20)4 2009
Abstract
We add a new classic case of amyloid goiter that differs from other reported cases in its association with intrathyroid parathyroid and lymphoepthelial cyst involved with amyloidosis. The presence of parathyroid tissue inside the thyroid parenchyma and surrounded by amyloid material elicited a diagn...
|
PMID: 19697162
PDF is available here.
PDF is available here.
Endocrine Pathology (20)4 2009
Abstract
Intraductal lesions of the pancreas are usually due to intraductal papillary mucinous neoplasms and the less common intraductal tubular adenoma. Cases of acinar cell carcinoma within intraductal location have also been encountered recently. Pancreatic neuroendocrine tumors are rarely...
|
PMID: 19763904
PDF is available here.
PDF is available here.
Endocrine Pathology (20)4 2009
Abstract
We add a new classic case of amyloid goiter that differs from other reported cases in its association with intrathyroid parathyroid and lymphoepthelial cyst involved with amyloidosis. The presence of parathyroid tissue inside the thyroid parenchyma and surrounded by amyloid material elicited a diagn...
|
PMID: 19697162
PDF is available here.
PDF is available here.
Endocrine Pathology (20)4 2009
Abstract
Intraductal lesions of the pancreas are usually due to intraductal papillary mucinous neoplasms and the less common intraductal tubular adenoma. Cases of acinar cell carcinoma within intraductal location have also been encountered recently. Pancreatic neuroendocrine tumors are rarely...
|
PMID: 19763904
PDF is available here.
PDF is available here.
Endocrine Pathology (20)4 2009
Abstract
We add a new classic case of amyloid goiter that differs from other reported cases in its association with intrathyroid parathyroid and lymphoepthelial cyst involved with amyloidosis. The presence of parathyroid tissue inside the thyroid parenchyma and surrounded by amyloid material elicited a diagn...
|
PMID: 19697162
PDF is available here.
PDF is available here.
Endocrine Pathology (20)4 2009
Abstract
Intraductal lesions of the pancreas are usually due to intraductal papillary mucinous neoplasms and the less common intraductal tubular adenoma. Cases of acinar cell carcinoma within intraductal location have also been encountered recently. Pancreatic neuroendocrine tumors are rarely...
|
PMID: 19763904
PDF is available here.
PDF is available here.
Endocrine Pathology (20)4 2009
Abstract
We add a new classic case of amyloid goiter that differs from other reported cases in its association with intrathyroid parathyroid and lymphoepthelial cyst involved with amyloidosis. The presence of parathyroid tissue inside the thyroid parenchyma and surrounded by amyloid material elicited a diagn...
|
PMID: 19697162
PDF is available here.
PDF is available here.
Endocrine Pathology (20)4 2009
Abstract
Intraductal lesions of the pancreas are usually due to intraductal papillary mucinous neoplasms and the less common intraductal tubular adenoma. Cases of acinar cell carcinoma within intraductal location have also been encountered recently. Pancreatic neuroendocrine tumors are rarely...
|
PMID: 19763904
PDF is available here.
PDF is available here.
Endocrine Pathology (20)4 2009
Abstract
We add a new classic case of amyloid goiter that differs from other reported cases in its association with intrathyroid parathyroid and lymphoepthelial cyst involved with amyloidosis. The presence of parathyroid tissue inside the thyroid parenchyma and surrounded by amyloid material elicited a diagn...
|
PMID: 19697162
PDF is available here.
PDF is available here.
Endocrine Pathology (20)4 2009
Abstract
Intraductal lesions of the pancreas are usually due to intraductal papillary mucinous neoplasms and the less common intraductal tubular adenoma. Cases of acinar cell carcinoma within intraductal location have also been encountered recently. Pancreatic neuroendocrine tumors are rarely...
|
PMID: 19763904
PDF is available here.
PDF is available here.
Abstract
Abstract
We report a case of breast carcinoma in which most of the areas studied on the tissue section showed neuroendocrine differentiation....
|
PMID: 19136787
PDF is available here.
PDF is available here.
Abstract
Chromaffin vesicles (CV) are highly sophisticated secretory organelles synthesized in adrenal medullary chromaffin cells. They contain a complex mixture of structural proteins, catecholamine neurotransmitters, peptide hormones, and the relative processing enzymes, as well as protease inhibitors. In...
|
PMID: 19037853
PDF is available here.
PDF is available here.
Abstract
We described 7 examples of Merkel cell carcinoma of the skin with eccrine and squamous differentiation. Five patients were men, and 2 were women; and their ages ranged from 63 to 81 years (mean age, 73 years). Six tumors arose in the head and neck; and one, on the sole of the right foot. Three tumor...
|
PMID: 18995205
PDF is available here.
PDF is available here.
Electrophoresis (29)20 2008
Abstract
Media conditioned by dysfunctioning pancreatic beta cells offer an excellent source of potential protein markers associated with this phenotype. Proteins identified from cell culture model systems are often found to be of importance clinically. Previous work by us and others have shown that low-pass...
|
PMID: 18924105
PDF is available here.
PDF is available here.
Molecular Endocrinology (22)8 2008
Abstract
We previously demonstrated that secretogranin III binds chromogranin A and targets it to the secretory granules in pituitary corticotrope-derived AtT-20 cells. However, secretogranin III has not been identified in adrenal chromaffin and PC12 cells, where chromogranin A is correctly sorted to the sec...
|
PMID: 18483175
PDF is available here.
PDF is available here.
Transgenic Research (17)4 2008
Abstract
We used this method to identify a mouse gene of unknown function and to establish a mutant mouse line. We subsequently identified one gene, denoted Ayu17-449, on mouse chromosome 3 that comprised 14 exons encoding 1920 amino acids with a granin motif in its N-terminal sequence. In adult mice, this g...
|
PMID: 18288583
PDF is available here.
PDF is available here.
Regulatory Peptides (148)1-3 2008
Abstract
Increased plasma concentrations were recorded in 11, 4 and 3 of the patients with the SgII 154-165 (N-terminal secretoneurin), the SgII 172-186 (C-terminal Secretoneurin) and the SgII 225-242 assays respectively. The SgIII, SgV, PC1/3 and PC2 assays failed to detect increased concentrations in any o...
|
PMID: 18448176
PDF is available here.
PDF is available here.
Abstract
Abstract
We have analyzed our clinical experience of eight patients with hepatic primary NET. From January 1997 to December 2006, eight patients with a mean age of 50.4 +/- 9.5 years underwent liver resection for primary hepatic NET. Seven patients underwent preoperative liver biopsies, which correctly diagn...
|
PMID: 18046612
PDF is available here.
PDF is available here.
Abstract
We believe that radical resection, with the aim of complete tumor removal and cure, is the treatment of choice....
|
PMID: 17992565
PDF is available here.
PDF is available here.
Pathology International (58)3 2008
Abstract
A unique case of ganglioneuroma mimicking a lipomatous tumor in a 73-year-old man is reported. The tumor was incidentally found on radiography performed for unrelated reasons. Because of the fat element, CT and magnetic resonance imaging suggested myelolipoma inside or outside the right adrenal glan...
|
PMID: 18251782
PDF is available here.
PDF is available here.
Clinical Cancer Research (14)5 2008
Abstract
All four cases of testicular carcinoid tumor arose in a background of mature teratoma. Isochromosome 12p was identified in carcinoid tumor cells in all four samples. 12p overrepresentation was also observed in three cases. Isochromosome 12p and 12p overrepresentation were present in cells of coexist...
|
PMID: 18316560
PDF is available here.
PDF is available here.
Journal of Anatomy (212)3 2008
Abstract
We have described the development of region-specific antibodies against CgA and CgB. In this study we describe antibodies to SgII and SgIII and their usefulness for immunohistochemical staining. Peptides homologous to defined parts of secretogranins II and III were selected and synthesized. Antibodi...
|
PMID: 18221483
PDF is available here.
PDF is available here.
Abstract
OBJECTIVE: To report a case of a patient who developed an acute and transient, tender, and bilateral swelling of the thyroid that occurred during fine-needle aspiration (FNA) of a solitary nodule in the left thyroid lobe; to add accurate ultrasound measurements to support our clinical observation; a...
|
PMID: 18302522
PDF is available here.
PDF is available here.
Abstract
A 70-year-old woman was examined for a 4-mm bluish nodule in the left upper eyelid. The lesion was excised and pathology showed it to be endocrine mucin-producing sweat gland carcinoma with positive margins. She underwent Mohs surgery and reconstruction of the resulting defect. Clinicians should be...
|
PMID: 18356733
PDF is available here.
PDF is available here.
Abstract
We describe a case of non-functioning pituitary adenoma in a 35-year-old woman with a prior history of fertility problems. The patient had received clomiphen citrate and human chorionic gonadotrophin for 3 years. Histological examination of the tumor revealed signet ring-like cell areas admixed with...
|
PMID: 18207654
PDF is available here.
PDF is available here.
Abstract
We report a case of a 73-year-old female with a rare simultaneous occurrence of three tumors: ovarian carcinoma, endometrial carcinoma, and breast carcinoma. The ovarian tumor was a primary pure large-cell neuroendocrine carcinoma. Grossly, the left ovary was enlarged by a solid tumor that measured...
|
PMID: 18164557
PDF is available here.
PDF is available here.
Neuroscience (151)1 2008
Abstract
We submitted inbred RHA (RHA-I), inbred RLA (RLA-I) and Sprague-Dawley-OFA (SD-OFA) rats to a sensitization regimen with amphetamine and studied the behavioral response to an amphetamine challenge after a 2-week withdrawal period. The expression patterns of nerve growth factor inducible clone A (NGF...
|
PMID: 18093743
PDF is available here.
PDF is available here.
Yonsei Medical Journal (48)6 2007
Abstract
We described an 82-year-old female patient with primary small cell carcinoma of the liver. Histologically, the tumor showed typical morphology of a pulmonary small cell carcinoma. Immunohistochemically, the tumor revealed neuroendocrine differentiation; positive reaction for chromogranin, synaptophy...
|
PMID: 18159605
PDF is available here.
PDF is available here.
Abstract
Abstract
Synchronous and metachronous ovarian and appendiceal mucinous tumors are often the subject of diagnostic consultations in gynecologic pathology practices to address whether the tumors are independent neoplasms or related as primary and metastasis. Those with goblet cell carcinoidlike patterns have n...
|
PMID: 17895750
PDF is available here.
PDF is available here.
Abstract
We report a series of 21 renal carcinoid tumors, with emphasis on histopathologic features and clinical outcomes. Patient age ranged from 27 to 78 years (average 52 y). The majority of specimens consisted of radical nephrectomies with or without associated lymph node dissection. Nine tumors were pre...
|
PMID: 17895755
PDF is available here.
PDF is available here.
Histopathology (51)3 2007
Abstract
Abstract
We report 2 unusual cases of hypervascular masses in the parapharyngeal space. The first case involved a poorly differentiated metastatic carcinoma of oropharyngeal origin that mimicked a carotid body tumor. The second case involved a highly vascular myoepithelioma located in the parapharyngeal spac...
|
PMID: 17702321
PDF is available here.
PDF is available here.
Pathologica (99)3 2007
Abstract
Jugulo-tympanic paraganglioma is the most commonly recognized neoplasia involving the middle ear, arising from chemopressure receptors. Clinical presentation is variable, with otalgia, dizziness and cranial nerve palsies. This tumor usually occurs in middle aged women and its presentation may be fam...
|
PMID: 17987728
PDF is available here.
PDF is available here.
Diagnostic Cytopathology (35)5 2007
Abstract
We present clinicopathological and cytological findings of a well-defined breast mass in a patient with history of primary renal carcinoid tumor. Fine-needle aspiration (FNA) cytology showed monotonous tumor cells with plasmacytoid appearance arranged singly and in small clusters. Occasional tumor c...
|
PMID: 17427210
PDF is available here.
PDF is available here.
Glycobiology (17)5 2007
Abstract
We previously demonstrated that cyclophilin B (CyPB) triggers chemotaxis and integrin-mediated adhesion of T lymphocytes mainly of the CD4+/CD45RO+ phenotype. These activities are related to interactions with two types of binding sites, CD147 and cell surface HS. Here, we demonstrate that CyPB-media...
|
PMID: 17267519
PDF is available here.
PDF is available here.
Der Pathologe (28)3 2007
Abstract
Sex cord markers comprise proteins and hormones that are produced in sex cord-derivatives in normal ovaries and testes as well as in gonadal sex cord-stromal tumors. Sex cord markers (e.g. inhibin-alpha) are used clinically as serum tumor markers. Immunohistochemical staining of sex...
|
PMID: 17429635
PDF is available here.
PDF is available here.
Journal of Biological Chemistry (282)17 2007
Abstract
We have recently shown that pancreatic islet betagranin levels are down-regulated in obese, leptin-deficient mice. In the present study, we have investigated the distribution of betagranin in primary mouse islets and cells of the MIN6 line and have evaluated its effects on insulin secretion. We show...
|
PMID: 17289672
PDF is available here.
PDF is available here.
Abstract
We report an additional case and review the literature. The patient is a 41-year-old man with a 5-year history of progressive dyspnea, cough, and wheezing. He was initially diagnosed as having bronchial asthma but did not respond to treatment of bronchodilators and inhaled steroids. Pulmonary functi...
|
PMID: 17349572
PDF is available here.
PDF is available here.
Abstract
The peripheral primitive neuroectodermal tumour (pPNET) is a rare and highly malignant soft tissue neoplasm in children and young adults. We present a case of pPNET of the maxilla in a 49-year-old woman.
|
PMID: 16203064
PDF is available here.
PDF is available here.
Abstract
We favor that in this case carcinoma arose in the trichilemmal cyst rather than being a collision tumor. This hypothesis is also supported by the recent observation that Merkel cells are frequently present within normal hair follicles, especially in the isthmic portion that corresponds with the area...
|
PMID: 17414443
PDF is available here.
PDF is available here.
Abstract
Genetic variations in the SCG3 gene may influence the risk of obesity through possible regulation of hypothalamic neuropeptide secretion....
|
PMID: 17200173
PDF is available here.
PDF is available here.
Abstract
Abstract
The existence of non-small cell lung carcinoma with neuroendocrine differentiation as a distinct entity and its relevance for prognostic and treatment purposes is controversial. This study assesses the frequency and biologic and prognostic significance of neuroendocrine (NE) expression of synaptophy...
|
PMID: 17197916
PDF is available here.
PDF is available here.