Find your PDFs fast.
Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Myelin Proteins (4):
Recent article
Myelin Proteins
Abstract
We hypothesized that early endoplasmic reticulum (ER) stress, which is associated with clinical triggers of PAH including hypoxia, bone morphogenetic protein receptor II mutations, and HIV/herpes simplex virus infections, explains the mitochondrial abnormalities and has a causal role in PAH. We show...
|
PMID: 21697531
PDF is available here.
PDF is available here.
| < More recent | Older article > |
Abstract
Abstract
Copy number variations (CNV) within the genome are extremely abundant. In this closeup, Canales and Walz discuss how CNV are associated with normal variation, genomic disorders, genome evolution, adaptive traits and how the use of a novel screen described by Ermakova et al in this is...
|
PMID: 21204264
PDF is available here.
PDF is available here.
Annals of Neurology (68)1 2010
Abstract
We present and validate a new rat model for muscle spasms after incomplete SCI and show that both intrathecal anti-Nogo-A antibody treatment and locomotor training, started early after injury, permanently reduce the development of muscle spasms.
The results show that an antibody-medi...
|
PMID: 20582944
PDF is available here.
PDF is available here.
Annals of Neurology (68)1 2010
Abstract
We present and validate a new rat model for muscle spasms after incomplete SCI and show that both intrathecal anti-Nogo-A antibody treatment and locomotor training, started early after injury, permanently reduce the development of muscle spasms.
The results show that an antibody-medi...
|
PMID: 20582944
PDF is available here.
PDF is available here.
Annals of Neurology (68)1 2010
Abstract
We present and validate a new rat model for muscle spasms after incomplete SCI and show that both intrathecal anti-Nogo-A antibody treatment and locomotor training, started early after injury, permanently reduce the development of muscle spasms.
The results show that an antibody-medi...
|
PMID: 20582944
PDF is available here.
PDF is available here.
Annals of Neurology (68)1 2010
Abstract
We present and validate a new rat model for muscle spasms after incomplete SCI and show that both intrathecal anti-Nogo-A antibody treatment and locomotor training, started early after injury, permanently reduce the development of muscle spasms.
The results show that an antibody-medi...
|
PMID: 20582944
PDF is available here.
PDF is available here.
Annals of Neurology (68)1 2010
Abstract
We present and validate a new rat model for muscle spasms after incomplete SCI and show that both intrathecal anti-Nogo-A antibody treatment and locomotor training, started early after injury, permanently reduce the development of muscle spasms.
The results show that an antibody-medi...
|
PMID: 20582944
PDF is available here.
PDF is available here.
Annals of Neurology (68)1 2010
Abstract
We present and validate a new rat model for muscle spasms after incomplete SCI and show that both intrathecal anti-Nogo-A antibody treatment and locomotor training, started early after injury, permanently reduce the development of muscle spasms.
The results show that an antibody-medi...
|
PMID: 20582944
PDF is available here.
PDF is available here.
Annals of Neurology (68)1 2010
Abstract
We present and validate a new rat model for muscle spasms after incomplete SCI and show that both intrathecal anti-Nogo-A antibody treatment and locomotor training, started early after injury, permanently reduce the development of muscle spasms.
The results show that an antibody-medi...
|
PMID: 20582944
PDF is available here.
PDF is available here.
Annals of Neurology (68)1 2010
Abstract
We present and validate a new rat model for muscle spasms after incomplete SCI and show that both intrathecal anti-Nogo-A antibody treatment and locomotor training, started early after injury, permanently reduce the development of muscle spasms.
The results show that an antibody-medi...
|
PMID: 20582944
PDF is available here.
PDF is available here.
Annals of Neurology (68)1 2010
Abstract
We present and validate a new rat model for muscle spasms after incomplete SCI and show that both intrathecal anti-Nogo-A antibody treatment and locomotor training, started early after injury, permanently reduce the development of muscle spasms.
The results show that an antibody-medi...
|
PMID: 20582944
PDF is available here.
PDF is available here.
Annals of Neurology (68)1 2010
Abstract
We present and validate a new rat model for muscle spasms after incomplete SCI and show that both intrathecal anti-Nogo-A antibody treatment and locomotor training, started early after injury, permanently reduce the development of muscle spasms.
The results show that an antibody-medi...
|
PMID: 20582944
PDF is available here.
PDF is available here.
Annals of Neurology (68)1 2010
Abstract
We present and validate a new rat model for muscle spasms after incomplete SCI and show that both intrathecal anti-Nogo-A antibody treatment and locomotor training, started early after injury, permanently reduce the development of muscle spasms.
The results show that an antibody-medi...
|
PMID: 20582944
PDF is available here.
PDF is available here.
Annals of Neurology (68)1 2010
Abstract
We present and validate a new rat model for muscle spasms after incomplete SCI and show that both intrathecal anti-Nogo-A antibody treatment and locomotor training, started early after injury, permanently reduce the development of muscle spasms.
The results show that an antibody-medi...
|
PMID: 20582944
PDF is available here.
PDF is available here.
Annals of Neurology (68)1 2010
Abstract
We present and validate a new rat model for muscle spasms after incomplete SCI and show that both intrathecal anti-Nogo-A antibody treatment and locomotor training, started early after injury, permanently reduce the development of muscle spasms.
The results show that an antibody-medi...
|
PMID: 20582944
PDF is available here.
PDF is available here.
Annals of Neurology (68)1 2010
Abstract
We present and validate a new rat model for muscle spasms after incomplete SCI and show that both intrathecal anti-Nogo-A antibody treatment and locomotor training, started early after injury, permanently reduce the development of muscle spasms.
The results show that an antibody-medi...
|
PMID: 20582944
PDF is available here.
PDF is available here.
Annals of Neurology (68)1 2010
Abstract
We present and validate a new rat model for muscle spasms after incomplete SCI and show that both intrathecal anti-Nogo-A antibody treatment and locomotor training, started early after injury, permanently reduce the development of muscle spasms.
The results show that an antibody-medi...
|
PMID: 20582944
PDF is available here.
PDF is available here.
Annals of Neurology (68)1 2010
Abstract
We present and validate a new rat model for muscle spasms after incomplete SCI and show that both intrathecal anti-Nogo-A antibody treatment and locomotor training, started early after injury, permanently reduce the development of muscle spasms.
The results show that an antibody-medi...
|
PMID: 20582944
PDF is available here.
PDF is available here.
Annals of Neurology (68)1 2010
Abstract
We present and validate a new rat model for muscle spasms after incomplete SCI and show that both intrathecal anti-Nogo-A antibody treatment and locomotor training, started early after injury, permanently reduce the development of muscle spasms.
The results show that an antibody-medi...
|
PMID: 20582944
PDF is available here.
PDF is available here.
Annals of Neurology (68)1 2010
Abstract
We present and validate a new rat model for muscle spasms after incomplete SCI and show that both intrathecal anti-Nogo-A antibody treatment and locomotor training, started early after injury, permanently reduce the development of muscle spasms.
The results show that an antibody-medi...
|
PMID: 20582944
PDF is available here.
PDF is available here.
Annals of Neurology (68)1 2010
Abstract
We present and validate a new rat model for muscle spasms after incomplete SCI and show that both intrathecal anti-Nogo-A antibody treatment and locomotor training, started early after injury, permanently reduce the development of muscle spasms.
The results show that an antibody-medi...
|
PMID: 20582944
PDF is available here.
PDF is available here.
Annals of Neurology (68)1 2010
Abstract
We present and validate a new rat model for muscle spasms after incomplete SCI and show that both intrathecal anti-Nogo-A antibody treatment and locomotor training, started early after injury, permanently reduce the development of muscle spasms.
The results show that an antibody-medi...
|
PMID: 20582944
PDF is available here.
PDF is available here.
Annals of Neurology (68)1 2010
Abstract
We present and validate a new rat model for muscle spasms after incomplete SCI and show that both intrathecal anti-Nogo-A antibody treatment and locomotor training, started early after injury, permanently reduce the development of muscle spasms.
The results show that an antibody-medi...
|
PMID: 20582944
PDF is available here.
PDF is available here.
Annals of Neurology (68)1 2010
Abstract
We present and validate a new rat model for muscle spasms after incomplete SCI and show that both intrathecal anti-Nogo-A antibody treatment and locomotor training, started early after injury, permanently reduce the development of muscle spasms.
The results show that an antibody-medi...
|
PMID: 20582944
PDF is available here.
PDF is available here.
Abstract
We investigated 21 subjects with rare CNVs associated with CMT1A or HNPP by oligonucleotide-based comparative genomic hybridization microarrays and breakpoint sequence analyses, and we identified 17 unique CNVs, including two genomic deletions, ten genomic duplications, two complex rearrangements, a...
|
PMID: 20493460
PDF is available here.
PDF is available here.
Journal of Neuroscience (30)19 2010
Abstract
We selectively deleted Dicer and consequently gene expression regulation by mature miRNAs from Mus musculus SCs. Our results show that in the absence of Dicer, most SCs arrest at the promyelinating stage and fail to start forming myelin. At the molecular level, the promyelinating transcription facto...
|
PMID: 20463238
PDF is available here.
PDF is available here.
Abstract
Multiple sclerosis (MS) is a devastating neurological condition that mainly affects young adults and is associated with long-standing morbidity. The pathophysiology of MS is believed to involve immune-mediated multifocal lesions in the CNS that are characterized by inflammation, demyelination, and a...
|
PMID: 20448478
PDF is available here.
PDF is available here.
Abstract
This study suggests that behavioral training interacts with the effects of the axonal growth promoter, NEP 1-40, and may accelerate behavioral recovery after focal cortical ischemia....
|
PMID: 20075346
PDF is available here.
PDF is available here.
Nature Neuroscience (13)3 2010
Abstract
We found that mice lacking the type 2 CXC chemokine receptor (CXCR2) were relatively resistant to cuprizone-induced demyelination and that circulating CXCR2-positive neutrophils were important for cuprizone-induced demyelination. Our findings support a two-hit process of cuprizone-induced demyelinat...
|
PMID: 20154684
PDF is available here.
PDF is available here.
Abstract
We found that Nogo-A was also expressed on the surface of neural stem cells (NSCs). The possible effects of NSCs-expressed Nogo-A on the NSC transplantation for CNS repair were discussed....
|
PMID: 20374087
PDF is available here.
PDF is available here.
Journal of Neurotrauma (27)3 2010
Abstract
We therefore studied possible cellular mechanisms accompanying the recovery process in a non-human primate model system, in which the lateral frontal motor cortex areas controlling the preferred upper limb were unilaterally lesioned, and the animals eventually regained fine hand motor function. Immu...
|
PMID: 20030560
PDF is available here.
PDF is available here.
Neuropathology (30)1 2010
Abstract
We identified 82 NIG-interacting proteins by screening a high-density human protein microarray composed of 5000 proteins with a recombinant NIG protein as a probe. Following an intensive database search, we selected 12 neuron/oligodendrocyte-associated NIG interactors. Among them, we verified the mo...
|
PMID: 19508346
PDF is available here.
PDF is available here.
Neuropathology (30)1 2010
Abstract
We identified 82 NIG-interacting proteins by screening a high-density human protein microarray composed of 5000 proteins with a recombinant NIG protein as a probe. Following an intensive database search, we selected 12 neuron/oligodendrocyte-associated NIG interactors. Among them, we verified the mo...
|
PMID: 19508346
PDF is available here.
PDF is available here.
Neuropathology (30)1 2010
Abstract
We identified 82 NIG-interacting proteins by screening a high-density human protein microarray composed of 5000 proteins with a recombinant NIG protein as a probe. Following an intensive database search, we selected 12 neuron/oligodendrocyte-associated NIG interactors. Among them, we verified the mo...
|
PMID: 19508346
PDF is available here.
PDF is available here.
Neuropathology (30)1 2010
Abstract
We identified 82 NIG-interacting proteins by screening a high-density human protein microarray composed of 5000 proteins with a recombinant NIG protein as a probe. Following an intensive database search, we selected 12 neuron/oligodendrocyte-associated NIG interactors. Among them, we verified the mo...
|
PMID: 19508346
PDF is available here.
PDF is available here.
Neuropathology (30)1 2010
Abstract
We identified 82 NIG-interacting proteins by screening a high-density human protein microarray composed of 5000 proteins with a recombinant NIG protein as a probe. Following an intensive database search, we selected 12 neuron/oligodendrocyte-associated NIG interactors. Among them, we verified the mo...
|
PMID: 19508346
PDF is available here.
PDF is available here.
Neuropathology (30)1 2010
Abstract
We identified 82 NIG-interacting proteins by screening a high-density human protein microarray composed of 5000 proteins with a recombinant NIG protein as a probe. Following an intensive database search, we selected 12 neuron/oligodendrocyte-associated NIG interactors. Among them, we verified the mo...
|
PMID: 19508346
PDF is available here.
PDF is available here.
Neuropathology (30)1 2010
Abstract
We identified 82 NIG-interacting proteins by screening a high-density human protein microarray composed of 5000 proteins with a recombinant NIG protein as a probe. Following an intensive database search, we selected 12 neuron/oligodendrocyte-associated NIG interactors. Among them, we verified the mo...
|
PMID: 19508346
PDF is available here.
PDF is available here.
Neuropathology (30)1 2010
Abstract
We identified 82 NIG-interacting proteins by screening a high-density human protein microarray composed of 5000 proteins with a recombinant NIG protein as a probe. Following an intensive database search, we selected 12 neuron/oligodendrocyte-associated NIG interactors. Among them, we verified the mo...
|
PMID: 19508346
PDF is available here.
PDF is available here.
Neuropathology (30)1 2010
Abstract
We identified 82 NIG-interacting proteins by screening a high-density human protein microarray composed of 5000 proteins with a recombinant NIG protein as a probe. Following an intensive database search, we selected 12 neuron/oligodendrocyte-associated NIG interactors. Among them, we verified the mo...
|
PMID: 19508346
PDF is available here.
PDF is available here.
Neuropathology (30)1 2010
Abstract
We identified 82 NIG-interacting proteins by screening a high-density human protein microarray composed of 5000 proteins with a recombinant NIG protein as a probe. Following an intensive database search, we selected 12 neuron/oligodendrocyte-associated NIG interactors. Among them, we verified the mo...
|
PMID: 19508346
PDF is available here.
PDF is available here.
Neuropathology (30)1 2010
Abstract
We identified 82 NIG-interacting proteins by screening a high-density human protein microarray composed of 5000 proteins with a recombinant NIG protein as a probe. Following an intensive database search, we selected 12 neuron/oligodendrocyte-associated NIG interactors. Among them, we verified the mo...
|
PMID: 19508346
PDF is available here.
PDF is available here.
Neuropathology (30)1 2010
Abstract
We identified 82 NIG-interacting proteins by screening a high-density human protein microarray composed of 5000 proteins with a recombinant NIG protein as a probe. Following an intensive database search, we selected 12 neuron/oligodendrocyte-associated NIG interactors. Among them, we verified the mo...
|
PMID: 19508346
PDF is available here.
PDF is available here.
Neuropathology (30)1 2010
Abstract
We identified 82 NIG-interacting proteins by screening a high-density human protein microarray composed of 5000 proteins with a recombinant NIG protein as a probe. Following an intensive database search, we selected 12 neuron/oligodendrocyte-associated NIG interactors. Among them, we verified the mo...
|
PMID: 19508346
PDF is available here.
PDF is available here.
Journal of Cell Biology (188)2 2010
Abstract
We show that NogoDelta20 is internalized into neuronal cells by a Pincher- and rac-dependent, but clathrin- and dynamin-independent, mechanism. Pincher-mediated macroendocytosis results in the formation of NogoDelta20-containing signalosomes that direct RhoA activation and growth cone collapse. In c...
|
PMID: 20083601
PDF is available here.
PDF is available here.
Abstract
We compare functional differences and pathogenic potential of "monoclonal" T cell lines that recognize myelin oligodendrocyte glycoprotein (MOG) with the same transgenic TCR but are distinguished by an IFN-γ producing Th1-like and IL-17 producing Th17-like cytokine signature.
CD4(+) T cell lines we...
|
PMID: 21209700
PDF is available here.
PDF is available here.
Abstract
We show that Nogo receptor (NgR) participates in the regulation of Nanog expression via Stat3 pathway. Activation of NgR results in the phosphorylation of Stat3 and increases expression levels of Nanog mRNA and protein, which inhibits differentiation of embryoid bodies. This up-regulation of Nanog c...
|
PMID: 19400741
PDF is available here.
PDF is available here.
Abstract
We report a new Ser112Arg mutation in the PMP22 gene, identified in a patient with early-onset CMT and slowly progressive hearing impairment beginning in the second decade of life. We suggest that the Ser112Arg mutation in the PMP22 gene might have a causative role in the early-onset CMT with hearin...
|
PMID: 20453308
PDF is available here.
PDF is available here.
Abstract
These results in a clinically-relevant SCI model showed that significant neuroprotection can be obtained by combining an initial acute IV injection of MP with continuously infused NEP1-40....
|
PMID: 20515570
PDF is available here.
PDF is available here.
Abstract
We performed an analysis of the equilibrium conformations of this peptide using the Replica Exchange Molecular Dynamics technique in conjunction with the Generalized Born continuum solvent model. Four variants of the peptide, stabilized by a disulfide bond, were also studied. We found that a signifi...
|
PMID: 19891505
PDF is available here.
PDF is available here.
Rinsho Shinkeigaku (49)11 2009
Abstract
We have reported a novel HMSN with proximal dominancy (HMSN-P) originated in Okinawa and Shiga prefectures, Japan. The gene locus is located in the centromere region of chromosome 3. In 2008, a new family with the HMSN-P was reported from Brazilians of Japanese ancestry. This Brazilian family was in...
|
PMID: 20030257
PDF is available here.
PDF is available here.
Neurogenetics (10)4 2009
Abstract
We identified a homozygous p.A335V mutation in the MED25 gene in an extended Costa Rican family with autosomal recessively inherited Charcot-Marie-Tooth neuropathy linked to the CMT2B2 locus in chromosome 19q13.3. MED25, also known as ARC92 and ACID1, is a subunit of the human activator-recruited co...
|
PMID: 19290556
PDF is available here.
PDF is available here.
Journal of Immunology (183)6 2009
Abstract
We investigated autoantibodies to myelin surface Ags in a large cohort of pediatric MS cases by flow cytometric labeling of transfectants that expressed different myelin proteins. Although Abs to native myelin oligodendrocyte glycoprotein (MOG) were uncommon among adult-onset patients, a subset of p...
|
PMID: 19687098
PDF is available here.
PDF is available here.
Abstract
We describe the generation and molecular characterization of an OMgp allelic series. With a single gene targeting event and Cre/FLP mediated recombination, we generated an OMgp null allele with a LacZ reporter, one without a reporter gene, and an OMgp conditional allele. This allelic series will aid...
|
PMID: 19672953
PDF is available here.
PDF is available here.
Abstract
The relation of Nogo-B to atherosclerotic plaque progression is not well understood. Thus, the purpose of this study was to assess the expression of Nogo-B in fibroatheromas (FA) of different stages, classified using virtual histology intravascular ultrasound (VH-IVUS) analysis in 19 autopsied cases...
|
PMID: 19654939
PDF is available here.
PDF is available here.
Abstract
We identified Charcot-Marie-Tooth disease type 1A (CMT1A) in a family with schwannomas in the spinal cord and median nerve. The CMT1A in this family showed an autosomal dominant pattern, like other CMT patients with PMP22 duplication, and the family also indicated a possible genetic predisposition t...
|
PMID: 19654968
PDF is available here.
PDF is available here.
Abstract
These results provide the first evidence that RNA-binding proteins affect the invasive and rapid growth characteristics of glioma cell lines. Its actions on proliferation appear to be mediated, in part, through alternative splicing of RTN4....
|
PMID: 19506066
PDF is available here.
PDF is available here.
Abstract
Tree shrews are small mammals that bear some semblance to squirrels, but are actually close relatives of primates. Thus, they have been extensively studied as a model for the early stages of primate evolution. In this study, subdivisions of cortex were reconstructed from brain sections cut in the co...
|
PMID: 19462403
PDF is available here.
PDF is available here.
Schizophrenia Research (112)1-3 2009
Abstract
We hypothesized that middle second trimester infection (E16) in mice may lead to a different pattern of brain gene expression and structural defects in the developing offspring. C57BL6 mice were infected on E16 with a sublethal dose of human influenza virus or sham-infected using vehicle solution. M...
|
PMID: 19487109
PDF is available here.
PDF is available here.