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Salivary Proteins and Peptides (6):
Recent article
Salivary Proteins and Peptides
Abstract
We were not able to determine serum stability; the peptide consisting of 36 amino acid residues is subject to cleavage by endopetidases. Three of the homologated compounds, 2b, 2c, and 5c, were shown to be agonists (Fig. 7 and 11). A comparison of terminal homologation with other stability-increas...
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PMID: 21560227
PDF is available here.
PDF is available here.
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Abstract
The aim of this study is to compare salivary and serum biomarker levels and degrees of matrix metalloproteinase (MMP) activation between patients with acute myocardial infarction (AMI) and systemically healthy patients (non-AMI) with similar periodontal conditions.
A...
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PMID: 21091346
PDF is available here.
PDF is available here.
Abstract
We sought to determine whether the treatment of mice with Salp15 during EAE induction would prevent the generation of proinflammatory T cell responses and the development of the disease. Surprisingly, Salp15-treated mice developed more severe EAE than control animals. The treatment of EAE-induced mi...
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PMID: 20920474
PDF is available here.
PDF is available here.
Abstract
We ectopically expressed either PSP94 or CRISP-3 alone or PSP94 along with CRISP-3 in three prostate cell lines (PC3, WPE1-NB26 and LNCaP) and performed growth inhibition assays. Reverse transcription-polymerase chain reaction and Western blot analysis were used to screen prostate cell lines for PSP...
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PMID: 20676114
PDF is available here.
PDF is available here.
Abstract
Abstract
Elastase concentrations maintained stable during the follow-up, while myeloperoxidase concentrations increased significantly after delivery. During pregnancy, MMP-8 concentrations were significantly lower than postpartum concentrations, being lowest during the second trimester and highest after deli...
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PMID: 20412421
PDF is available here.
PDF is available here.
Abstract
We investigated whether Mediterranean goats use salivary tannin-binding proteins to cope with tannin-rich forages by determining the affinity of salivary or parotid gland proteins for tannic acid or quebracho tannin. Mixed saliva, sampled from the oral cavity, or parotid gland contents were compared...
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PMID: 20559693
PDF is available here.
PDF is available here.
Abstract
Salivary sCD44 might be considered a biomarker of periodontal destruction in smokers and non-smokers. The research opens the door to further research into a role for CD44 as a diagnostic marker for periodontitis....
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PMID: 20429650
PDF is available here.
PDF is available here.
Biochemistry (New York) (75)5 2010
Abstract
The relative location of proteins and lipids in particles of medicinal leech salivary gland secretion (SGS) is revealed for the first time. Their sizes and morphology are described. Using scanning electron microscopy and transmission electron microscopy, it was determined that SGS consists of partic...
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PMID: 20632937
PDF is available here.
PDF is available here.
British Dental Journal (208)7 2010
Abstract
The washer-disinfector is the most effective method of cleaning photographic retractors, but no method was found to be 100% successful at removing amylase and albumin....
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PMID: 20357820
PDF is available here.
PDF is available here.
Abstract
Hyposalivation is represented by a reduced salivary flow rate and can be caused by etiologic factors such as systemic diseases and intake of various medications or by radiotherapy following head and neck cancer. The aim of this review was to compile data about the qualitative and quantitative change...
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PMID: 20305867
PDF is available here.
PDF is available here.
Archives of Oral Biology (55)4 2010
Abstract
We investigated the interaction occurring between oil-in-water emulsion droplets, stabilized by different emulsifiers, i.e. lysozyme and beta-lactoglobulin (beta-lg), and salivary proteins (SPs) with a molecular mass (M(r)) above about 10kDa. Different techniques, i.e. infrared spectroscopy, Western...
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PMID: 20197185
PDF is available here.
PDF is available here.
Abstract
We aimed to investigate an eventual role of ethanol both in astringency and salivary protein-enological tannin interactions. A trained sensory panel scored perceived astringency. Salivary protein-tannin interactions were assessed by observing both tannin-dependent changes in salivary protein diffusi...
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PMID: 20158256
PDF is available here.
PDF is available here.
Abstract
We developed a primary culture of Rhodnius prolixus salivary gland and main salivary canal cells. Cells remained viable in culture for 30 days. Three types of cells were indentified in the salivary gland cultures, with binuclear cells being the most abundant. The supernatants of salivary cultures co...
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PMID: 20428670
PDF is available here.
PDF is available here.
Abstract
FA patients may exhibit significant changes in SSFR, calcium, and urea concentration of saliva....
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PMID: 20147854
PDF is available here.
PDF is available here.
Abstract
Salivary IL-6 concentrations were elevated in patients with periodontitis with or without diabetes. Salivary MMP-8 and OPG concentrations were elevated regardless of periodontal inflammation in patients with diabetes. Therefore, periodontitis and diabetes are conditions that may interfere with prote...
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PMID: 20192865
PDF is available here.
PDF is available here.
Abstract
We hypothesized that oral malodor would be associated with enhanced proteolysis or deglycosylation in saliva. The purpose of this study was to evaluate properties of glycoproteins in saliva and assess their association with VSC levels. Subjects were 88 patients who visited "the Fresh Breath Clinic",...
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PMID: 20437763
PDF is available here.
PDF is available here.
Oral Diseases (16)2 2010
Abstract
Handheld mobile phones (MPHs) have become a 'cultural' accessory device, no less so than a wrist watch. Nevertheless, the use of MPHs has given rise to great concern because of possible adverse health effects from exposure to the radiofrequency radiation (RFR) emitted by the device....
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PMID: 19744173
PDF is available here.
PDF is available here.
Oral Diseases (16)2 2010
Abstract
Handheld mobile phones (MPHs) have become a 'cultural' accessory device, no less so than a wrist watch. Nevertheless, the use of MPHs has given rise to great concern because of possible adverse health effects from exposure to the radiofrequency radiation (RFR) emitted by the device....
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PMID: 19744173
PDF is available here.
PDF is available here.
Oral Diseases (16)2 2010
Abstract
Handheld mobile phones (MPHs) have become a 'cultural' accessory device, no less so than a wrist watch. Nevertheless, the use of MPHs has given rise to great concern because of possible adverse health effects from exposure to the radiofrequency radiation (RFR) emitted by the device....
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PMID: 19744173
PDF is available here.
PDF is available here.
Abstract
Hydroxyapatite (HA) is used as a construction material for artificial supplementation of enamel tooth surfaces to improve oral hygiene. This study examined in vitro HA interactions with mutans streptococci (MS) and bacterial adherence to small (nanosize) crystal form of HA beads having a protean hex...
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PMID: 19907724
PDF is available here.
PDF is available here.
Abstract
We detected a significant lack in the overall expression of terminal sugar residues of MUC7 (stress value = 0.088).
We observed a strong positive correlation between the aberrant terminal sugar patterns in this sub group of CRS patients with biofilms. The innate immunity function of...
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PMID: 21244730
PDF is available here.
PDF is available here.
Abstract
RT-PCR evaluation of the activity of eight Ixodes persulcatus salivary gland genes shows clear distinctions in their expression depending of the stage of tick feeding. Out of them, only Salp 10 and Salp 15 proteins may be regarded as candidates for protective antigens to develop anti-tick and anti-B...
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PMID: 20608183
PDF is available here.
PDF is available here.
Journal of Oral Science (52)3 2010
Abstract
In astronauts and cosmonauts, exposure to microgravity has been associated with several physiological changes, including an osteoporosis like loss of bone mass. It has been reported that head-down tilt bed-rest studies mimic many of the observations seen in space flights. There has been no study of...
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PMID: 20881330
PDF is available here.
PDF is available here.
Journal of Oral Science (52)3 2010
Abstract
We thus evaluated saliva samples for levels of glucose, amylase and total protein, and assessed salivary flow rate in diabetics and healthy non-diabetics. We also analyzed these parameters with regard to duration and type of diabetes mellitus and gender, and aimed to assess the interrelationships am...
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PMID: 20881327
PDF is available here.
PDF is available here.
Thrombosis and Haemostasis (102)6 2009
Abstract
We evaluated the anticoagulant effect of the algal sulfated galactan using serpin-free plasma. In contrast to heparin, the sulfated galactan is still able to prolong coagulation time and delay thrombin and FXa generation in serpin-free plasma. We further investigated this effect using purified blood...
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PMID: 19967150
PDF is available here.
PDF is available here.
Journal of Periodontology (80)11 2009
Abstract
The activities of DPPIV in the LCP and GCP groups were not significantly different from one another, but both groups had significantly higher enzyme activities than the periodontally healthy group (P = 0.001). DPPIV activity was positively correlated with all clinical parameters and the prevalence o...
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PMID: 19905950
PDF is available here.
PDF is available here.
Abstract
We report on the reduction of nitrite in the absence of a second substrate at the heme center of the ferriheme protein nitrophorin 7 (NP7) resulting in the formation of NO and restoration of the ferriheme center. The product was spectroscopically characterized, in particular by resonance Raman and F...
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PMID: 19655755
PDF is available here.
PDF is available here.
Abstract
Interaction of taste molecules with saliva is the first step in the flavor perception process. Saliva is assumed to influence copper-induced sensation by controlling the copper solubility or causing astringency via binding of proteins with copper. This study was performed to identify the nature of c...
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PMID: 19572649
PDF is available here.
PDF is available here.
Abstract
We compared whole saliva samples of captive Theropithecus gelada and Papio hamadryas using gel electrophoresis and tannin-binding assay. We hypothesized that the amount of proline-rich salivary proteins with tannin-binding capacity is higher in baboons consuming a feed with high dicot/monocot ration...
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PMID: 19431194
PDF is available here.
PDF is available here.
Medical Science Monitor (15)8 2009
Abstract
Acute ingestion of a large dose of ethanol increased the activity of salivary exoglycosidases, which might be followed by subsequent degradation of proteins in saliva. The observed changes might contribute to salivary defense system malfunction as well as to oral malodor production....
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PMID: 19644418
PDF is available here.
PDF is available here.
Archives of Oral Biology (54)8 2009
Abstract
We have evaluated the effect of three different antidepressants in ecto-nucleotide pyrophosphatase/phosphodiesterase (E-NPP1-3) activities in cultured cells from salivary glands. Rats received imipramine (10mg/ml), fluoxetine (20mg/ml) or moclobemide (30mg/ml) by oral gavage. The drugs were administ...
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PMID: 19473651
PDF is available here.
PDF is available here.
Abstract
Rhodnius prolixus Nitrophorin 4 (abbreviated NP4) is an almost pure beta-sheet heme protein. Its dynamics is investigated by X-ray structure determination at eight different temperatures from 122 to 304 K and by means of Mössbauer spectroscopy. A comparison of this beta-sheet protein with the pur...
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PMID: 19271215
PDF is available here.
PDF is available here.
Insect Molecular Biology (18)3 2009
Abstract
We report the construction of a novel cDNA library from Culicoides nubeculosus linked to the analysis of abundant salivary gland proteins by mass spectrometry. Fifty-four novel proteins sequences are described including those of the enzymes maltase, hyaluronidase and two serine proteases demonstrate...
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PMID: 19523070
PDF is available here.
PDF is available here.
Legal Medicine (11)3 2009
Abstract
We have also demonstrated the feasibility of identifying body fluids by using a real-time RT-PCR assay. Statherin (STATH) and histatin (HTN3), the selected genes for saliva, and protamin 2 (PRM2) and semenogelin 1 (SEMG1), those selected for semen, showed high specificity to these body fluids. Thus,...
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PMID: 19036626
PDF is available here.
PDF is available here.
Legal Medicine (11)3 2009
Abstract
We have also demonstrated the feasibility of identifying body fluids by using a real-time RT-PCR assay. Statherin (STATH) and histatin (HTN3), the selected genes for saliva, and protamin 2 (PRM2) and semenogelin 1 (SEMG1), those selected for semen, showed high specificity to these body fluids. Thus,...
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PMID: 19036626
PDF is available here.
PDF is available here.
Legal Medicine (11)3 2009
Abstract
We have also demonstrated the feasibility of identifying body fluids by using a real-time RT-PCR assay. Statherin (STATH) and histatin (HTN3), the selected genes for saliva, and protamin 2 (PRM2) and semenogelin 1 (SEMG1), those selected for semen, showed high specificity to these body fluids. Thus,...
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PMID: 19036626
PDF is available here.
PDF is available here.
Legal Medicine (11)3 2009
Abstract
We have also demonstrated the feasibility of identifying body fluids by using a real-time RT-PCR assay. Statherin (STATH) and histatin (HTN3), the selected genes for saliva, and protamin 2 (PRM2) and semenogelin 1 (SEMG1), those selected for semen, showed high specificity to these body fluids. Thus,...
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PMID: 19036626
PDF is available here.
PDF is available here.
Abstract
The effectiveness of massage for postexercise recovery remains unclear, despite numerous studies on this issue. The aim of this study was to determine the effect of massage on endocrine and immune functions of healthy active volunteers after intense exercise. After repeated Wingate tests, the effect...
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PMID: 19197204
PDF is available here.
PDF is available here.
Abstract
We demonstrated that sialorphin can cause increased rates of relaxation of corporal smooth muscle (CSM). We have also demonstrated that in vitro, Vcsa1 causes changes in the expression of G-protein-coupled receptors (GPCRs). This has led us to suggest that the action of Vcsa1 on erectile physiology...
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PMID: 19267851
PDF is available here.
PDF is available here.
Abstract
We have replaced the native axial heme-coordinating histidine residue with glycine, alanine, and cysteine. We report here the characterization of the cysteine mutant H60C_NP1 by spectroscopic and crystallographic methods. The UV/vis, resonance Raman, and magnetic circular dichroism spectra suggest w...
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PMID: 18923851
PDF is available here.
PDF is available here.
Abstract
We have now studied the complex between human MSP and CRISP-3 with multidimensional NMR. 15N-HSQC spectra show substantial differences between free and complexed hMSP. Using several 3D-NMR spectra of triply labeled hMSP in complex with a recombinant N-terminal domain of CRISP-3, most of the backbone...
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PMID: 19026612
PDF is available here.
PDF is available here.
Srpski arhiv za celokupno lekarstvo (137)3-4 2009
Abstract
The values of most of the studied parameters exceeded the normal range in a high degree: CIC 72.5%, IgG 70%, SP 80%. The concentrations of CIC were significantly higher in the patients with the duration of disease less than 10 years. With the decrease of USFR, the concentration of slgA and IgG were...
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PMID: 19459558
PDF is available here.
PDF is available here.
Abstract
sIGF-I was significantly increased at the end of the physical exercise. The plasma free IGF-I concentrations did not demonstrate any difference. The saliva total protein level (sTP) was also significantly increased. A positive correlation between sTP and sIGF-I, was observed, both before and after p...
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PMID: 19337006
PDF is available here.
PDF is available here.
Abstract
Periodontitis is a chronic inflammatory disease characterized by tissue destruction which is usually diagnosed through clinical and radiographic signs. The detection of changes in the chemical composition of saliva could be used to reflect gingivo-periodontal alterations. The aim of this study was t...
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PMID: 19839486
PDF is available here.
PDF is available here.
Abstract
The aim of this study was to examine the relationship between serum and saliva levels of cancer antigen (CA) 125 and compare them among healthy women and patients with treated and untreated breast cancer.
CA125 levels were assayed in serum and unstimulated whole saliv...
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PMID: 20020075
PDF is available here.
PDF is available here.
Abstract
By using the guanidine-isothiocyanate test, the authors isolated a summary RNA preparation from Ixodes persulcatus salivary gland extracts. Activity products of the genes responsible for the expression of some salivary proteins were first identified using the RT-PCR. It has been shown that, firstly,...
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PMID: 19348314
PDF is available here.
PDF is available here.
The Journal of Medical Investigation (56 Suppl) 2009
Abstract
We developed a shotgun proteomic method using two-dimensional nano-flow LC tandem mass spectrometry. We report here that our method is able to detect proteins quantitatively even in small sample volumes of saliva....
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PMID: 20224185
PDF is available here.
PDF is available here.
BMC Genomics (10)1 2009
Abstract
A cDNA library from salivary glands of P. arabicus females was constructed and transcripts were sequenced and analyzed. The most abundant protein families identified were SP15-like proteins, ParSP25-like proteins, D7-related proteins, yellow-related proteins, PpSP32-like proteins, antigen 5-related...
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PMID: 19555500
PDF is available here.
PDF is available here.
BMC Genomics (10)1 2009
Abstract
A total of 2,371 clones randomly selected from an adult female An. darlingi SG cDNA library were sequenced and used to assemble a database that yielded 966 clusters of related sequences, 739 of which were singletons. Primer extension experiments were performed in selected clones to further extend se...
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PMID: 19178717
PDF is available here.
PDF is available here.
Malaria Journal (8)1 2009
Abstract
Specific IgG responses to gSG6-P1 were observed in children exposed to very low-level of Anopheles bites. In addition, a significant increase in the specific IgG Ab level was observed during the Anopheles exposure season whereas classical entomological data have reported very few or no Anopheles dur...
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PMID: 19674487
PDF is available here.
PDF is available here.
BMC Microbiology (9)1 2009
Abstract
We demonstrate here, using purified MUC7 to overlay blots of SDS-extracts of Streptococcus gordonii cell surface proteins, 4 MUC7-binding bands, with apparent molecular masses of 62, 78, 84 and 133 kDa from the Streptococcus gordonii strain, PK488. Putative adhesins were identified by in-gel digesti...
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PMID: 19671172
PDF is available here.
PDF is available here.
Abstract
These results suggest that analysis of salivary phospho-peptides might help to discriminate a considerable subgroup of ASD patients....
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PMID: 19367726
PDF is available here.
PDF is available here.
Abstract
Saliva is commonly referred to as the blood stream of the oral cavity. It has many functions, one of the major functions being protection of teeth against dental caries. There are many components in saliva, each one having a specific role in the prevention of dental caries. The composition of saliva...
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PMID: 19008624
PDF is available here.
PDF is available here.
Journal of Biological Chemistry (283)48 2008
Abstract
We report here the very specific expression of FDC-SP in junctional epithelium at the gingival crevice. This region is very important for the host defense against pathogens and for periodontal protection. To be able to better understand the function of FDC-SP, we developed a novel gene expression sy...
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PMID: 18806264
PDF is available here.
PDF is available here.
The Journal of Chemical Physics (129)18 2008
Abstract
The structural properties of the salivary protein statherin upon adsorption have been examined using a coarse-grained model and Monte Carlo simulation. A simple model system with focus on electrostatic interactions and short-ranged attractions among the uncharged amino acids has been used. To mimic...
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PMID: 19045429
PDF is available here.
PDF is available here.
FASEB Journal (22)11 2008
Abstract
We examined the properties of human saliva and the fractions that were obtained from saliva by high-performance liquid chromotography (HPLC) separation. We identified histatin 1 (Hst1) and histatin 2 (Hst2) as major wound-closing factors in human saliva. In contrast, the d-enantiomer of Hst2 did not...
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PMID: 18650243
PDF is available here.
PDF is available here.
Journal of Rheumatology (35)11 2008
Abstract
Serum and salivary concentrations of androgens were low in SS. Substrate to end-product ratios and correlations suggest that in SS salivary glands DHEA is effectively converted to testosterone, but that there are defects in converting testosterone further to dihydrotestosterone (DHT). In healthy con...
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PMID: 18843777
PDF is available here.
PDF is available here.
Physiology & Behavior (95)3 2008
Abstract
We conclude that salivary proteins in solution inhibit the mouthfeeling of astringency which is mediated, at least in part, by salivary proteins adhered to buccal mucosal cells....
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PMID: 18590751
PDF is available here.
PDF is available here.
Abstract
Salp15 Iric-1 interacts with all European Borrelia species but differentially protects B. burgdorferi from antibody-mediated killing, putatively giving this Borrelia species a survival advantage in nature....
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PMID: 18752445
PDF is available here.
PDF is available here.