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- Algal Proteins
- Amphibian Proteins
- Antifreeze Proteins
- Archaeal Proteins
- Armadillo Domain Proteins
- Avian Proteins
- Bacterial Proteins
- Blood Proteins
- Carrier Proteins
- Cell Cycle Proteins
- Cerebrospinal Fluid Proteins
- Contractile Proteins
- Cytoskeletal Proteins
- Dental Enamel Proteins
- Dietary Proteins
- DNA-Binding Proteins
- Dynein ATPase
- Egg Proteins
- Epididymal Secretory Proteins
- Eye Proteins
- Fanconi Anemia Complementation Group Proteins
- Fetal Proteins
- Fish Proteins
- Fungal Proteins
- GTP-Binding Protein Regulators
- Heat-Shock Proteins
- Helminth Proteins
- Immediate-Early Proteins
- Immobilized Proteins
- Insect Proteins
- Intercellular Signaling Peptides and Proteins
- Intracellular Signaling Peptides and Proteins
- Iron-Regulatory Proteins
- LDL-Receptor Related Proteins
- Luminescent Proteins
- Membrane Proteins
- Mitochondrial Proteins
- Molecular Chaperones
- Mutant Proteins
- Neoplasm Proteins
- Nerve Tissue Proteins
- Proteinase Inhibitory Proteins, Secretory
- Nuclear Proteins
- Oxidative Phosphorylation Coupling Factors
- Photoreceptors, Microbial
- Photosynthetic Reaction Center Complex Proteins
- Plant Proteins
- Pregnancy Proteins
- Protein Hydrolysates
- Protein Isoforms
- Protein Precursors
- Protein Subunits
- Protozoan Proteins
- Pulmonary Surfactant-Associated Proteins
- Receptors, Cytoplasmic and Nuclear
- Receptors, Drug
- Recombinant Proteins
- Reptilian Proteins
- Ribosomal Proteins
- Salivary Proteins and Peptides
- Selenium-Binding Proteins
- Seminal Plasma Proteins
- Silver Proteins
- Tissue Inhibitor of Metalloproteinases
- Transcription Factors
- Viral Proteins
Articles on Proteins
Nanotechnologies and regenerative medical approaches for space and terrestrial medicine.
We now refer to as nano-medicine--and regenerative medicine have enormous untapped potential for future space and terrestrial medical applications. Novel means for drug delivery and nanoscale screening tools will one day benefit astronauts venturing to Mars and places beyond, while the space laborat...
A high-throughput approach for measuring temporal changes in the interactome.
We combine quantitative proteomics and size-exclusion chromatography to map 291 coeluting complexes. This method allows mapping of an interactome to the same depth and accuracy as AP-MS with less work and without overexpression or tagging. The use of triplex labeling enables monitoring of interactom...
The use of hyaluronan to regulate protein adsorption and cell infiltration in nanofibrous scaffolds.
We developed a protein resistant and porous nanofibrous scaffold composed of hyaluronan (HA), silk fibroin (SF), and polycaprolactone (PCL) blends via one-step emulsion electrospinning. The scaffolds were characterized and evaluated for nanostructures, chemical composition, mechanical properties, hy...
The clinical and pathological phenotype of C9ORF72 hexanucleotide repeat expansions.
There is increasing evidence that frontotemporal dementia and amyotrophic lateral sclerosis are part of a disease continuum. Recently, a hexanucleotide repeat expansion in C9orf72 was identified as a major cause of both sporadic and familial frontotemporal dementia and amyotrophic la...
Shwachman-Diamond syndrome in India.
Preparation of phenyl-silica hybrid monolithic column with "one-pot" process for capillary liquid chromatography.
A phenyl-silica hybrid monolithic column for capillary liquid chromatography (cLC) was prepared through "one-pot" process by con-currently using benzyl methacrylate and alkoxysilanes. The effects of the molar ratio of tetramethoxysilane/vinyltrimethoxysilane (TMOS/VTMS), polycondensa...
Distinct clinical and pathological characteristics of frontotemporal dementia associated with C9ORF72 mutations.
We screened a cohort of 398 patients with frontotemporal dementia, progressive non-fluent aphasia, semantic dementia or mixture of these syndromes for mutations in the C9ORF72 gene. Motor neuron disease was present in 55 patients (14%). We identified 32 patients with C9ORF72 mutations, representing...
The AMPK stress response pathway mediates anoikis resistance through inhibition of mTOR and suppression of protein synthesis.
We show that, after detachment, mouse embryonic fibroblasts (MEFs) transformed by K-Ras(V12) or ETV6-NTRK3 (EN) activate a transcriptional response overrepresented by genes related to bioenergetic stress and the AMP-activated protein kinase (AMPK) energy-sensing pathway. Accordingly, AMPK is activat...
Investigation of endogenous metabolic changes in the urine of pseudo germ-free rats using a metabolomic approach
We prepared pseudo germ-free rats by antibiotic treatment, and we investigated urinary metabolite profiles of pseudo germ-free rats using UPLC-QTOF-MS based on metabolomics. The repeatability and stability of the analysis were evaluated using QC samples and testmixes in both positive and negative io...
Genetics. Gene losses in the human genome.