Abstract
Monoclonal antibody-based competitive ELISA (C-ELISA) has been used for the specific measurement of antibodies to peste des petits ruminants (PPR) viruses in sheep, goats, cattle and buffalo. Serum samples from sheep (n = 232), goats (n = 428), cattle (n = 43), buffalo (n = 89) were tested. The anim...
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PMID: 18716909
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Abstract
The one-humped camel (Camelus dromedarius) was first introduced to German South West Africa (Namibia) for military purposes in 1889. Introductions to the Cape of Good Hope (South Africa) in 1897 and Rhodesia (Zimbabwe) in 1903 were initially with a view to replacing oxen that died of rinderpest. Dis...
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PMID: 18846848
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Abstract
The Civil Veterinary Service on Java, Netherlands East-Indies, was established in 1853, more than 20 years after the introduction of the Cultivation System. During the 19th century its tasks were directed at the survey of livestock, esp. its health. Despite the fact that the number of veterinarians...
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PMID: 20642139
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Abstract
Between 1998 and 2005, the Regional Reference Laboratory at Bingerville (Ivory-Coast) received samples for analysis from Western and Central African countries. From a total of 606 sera; 65 tissue samples and 75 swabs received, no rinderpest virus or specific gene products or antibodies against rinde...
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PMID: 17316721
PDF is available here.
Abstract
Peste-des-petits-ruminants virus (PPRV) and rinderpest virus (RPV) are two morbilliviruses of economic relevance in African and Asian countries. Although efficient vaccines are available for both diseases, they cannot protect the animals before 14 days post-vaccination. In emergencies, it would be d...
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PMID: 17622636
PDF is available here.
Abstract
The nucleocapsid (N) protein of all morbilliviruses has a highly conserved central region that is thought to interact with and encapsidate the viral RNA. The C-terminal third of the N protein is highly variable among morbilliviruses and is thought to be located on the outer surface and to be availab...
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PMID: 17554036
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Abstract
We examined long-term monitoring data on different components of the Serengeti-Mara Ecosystem to trace the effects of disturbances and thus to elucidate cause-and-effect connections between them. The long-term data illustrated the role of food limitation in population regulation in mammals, particul...
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PMID: 17531037
PDF is available here.
Abstract
Peste des petits ruminants is a highly contagious viral disease of small ruminants making its diagnosis difficult from the similar symptoms of Rinderpest. Computer based prediction algorithms was applied to identify antigenic determinants on the nucleocapsid (N) protein of PPRV. Specificity and anti...
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PMID: 16962260
PDF is available here.
Abstract
Two previously unpublished manuscripts reveal how innovative the Austrian Low Countries were when they introduced an animal health policy to control rinderpest in 1769. The policy was novel in that it replaced the slaughter of individual sick animals with herd slaughter. Unfortunately, a number of n...
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PMID: 17361762
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Abstract
A single-tube one-step multiplex RT-PCR was standardized to amplify both 337 bp and 191 bp fragments of N and M genes of peste des petits ruminants virus (PPRV), respectively, and only a 337 bp fragment of N gene of Rinderpest virus (RPV). The RT-PCR using purified viral RNA was easily adopted for d...
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PMID: 16838207
PDF is available here.
Abstract
We report surveillance for rinderpest virus in wildlife populations in three major ecosystems of East Africa: Great Rift Valley, Somali and Tsavo from 1994 to 2003. Three hundred and eighty wild animals were sampled for detection of rinderpest virus, antigen or genome and 1133 sampled for antibody i...
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PMID: 16551482
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Abstract
Eight hundred and thirty five serum samples collected from eight wild artiodactyl species in Kenya and Tanzania between 1982 and 1993 were tested for virus-neutralising (VN) antibodies to rinderpest (RP) virus. Antibodies were found in 116 of 344 buffaloes (Syncerus caffer) but not in the other spec...
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PMID: 16529830
PDF is available here.
Abstract
The ability of the attenuated vaccine 75/1 of peste des petits ruminants to interfere with rinderpest vaccination in cattle was investigated experimentally. Young cattle (93) were selected and tested as being negative for antibodies against RP or PPR viruses. These were vaccinated with the peste des...
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PMID: 16757064
PDF is available here.
Abstract
The matrix (M) protein of paramyxoviruses forms an inner coat to the viral envelope and serves as a bridge between the surface glycoproteins (F and H) and the ribonucleoprotein core. Previously, a marker vaccine (RPV-PPRFH) was produced for the control of peste des petits ruminants (PPR) disease, wh...
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PMID: 16760405
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Abstract
We conclude that since there has been no outbreak of this pandemic, it is logical to assert that the veterinary services of this country are doing a sterling job, given that there are countries in Africa today where the disease is smoldering....
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PMID: 18447300
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Abstract
Rinderpest, or cattle plague, is caused by Rinderpest virus (RPV), which is related most closely to human Measles virus (MV), both being members of the genus Morbillivirus, a group of viruses known to have strong immunosuppressive effects in vitro and in vivo. Here, it was shown that peripheral bloo...
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PMID: 16298981
PDF is available here.
Abstract
The authors provide a report on the surveillance of rinderpest virus (RPV) and peste des petits ruminants virus (PPRV) in the wildlife population in Côte d'Ivoire. For this purpose, 266 animals from nine different species, selected according to susceptibility and abundance, were captured and sample...
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PMID: 16642757
PDF is available here.
Abstract
The development of a stochastic, state-transition model of rinderpest transmission dynamics is described using parameter estimates obtained from both laboratory and participatory research. Using serological data, the basic reproduction numbers for lineage-1 rinderpest virus in southern Sudan and for...
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PMID: 15907573
PDF is available here.
Abstract
Rinderpest virus (RPV) is a morbillivirus that causes cattle plague, a disease of large ruminants. The viral genome is flanked at the 3' and 5' genome termini by the genome promoter (GP) and antigenome promoter (AGP), respectively. These promoters play essential roles in directing replication and tr...
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PMID: 15784902
PDF is available here.
Abstract
The currently used vaccine strain of Rinderpest virus was derived by serial passage of the highly virulent Kabete 'O' strain (KO). A full-length cDNA copy of the KO strain was made from which a virus identical in pathogenicity to the wild-type virus was rescued. A series of chimeric viruses was prep...
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PMID: 15784903
PDF is available here.
Abstract
With few exceptions, vaccination aims to control rather than eliminate or eradicate disease. The eradication of smallpox in the 1970s led to two other human diseases, polio and measles, being targeted for eradication by the World Health Organization. In general, animal diseases are ignored by the pu...
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PMID: 15757478
PDF is available here.
Abstract
This paper provides an ex-ante economic analysis comparing four alternative intervention strategies for the control and eradication of rinderpest against a scenario of no intervention in a cattle population similar in size to that of Ethiopia. The interventions were three different coverage levels o...
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PMID: 15861869
PDF is available here.
Abstract
We previously demonstrated that the rinderpest virus (RPV) hemagglutinin (H) protein plays an important role in determining host range but that other viral proteins are clearly required for full RPV pathogenicity to be manifest in different species. To examine the effects of the RPV nucleocapsid (N)...
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PMID: 15163758
PDF is available here.
Abstract
We have developed transgenic peanut (Arachis hypogaea L.) plants expressing hemagglutinin (H) protein of rinderpest virus (RPV), which is antigenically authentic. In this work, we have evaluated the immunogenicity of peanut-expressed H protein using mouse model, administered parenterally as well as...
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PMID: 15193924
PDF is available here.
Abstract
Peste des petits ruminants (PPR) is an emerging, economically important viral disease of goats and sheep in the Indian subcontinent. In the present investigation, 15 hill goats were experimentally infected with 2 ml of 10% splenic suspension of a virulent isolate of PPR virus (PPR/Izatnagar/94) that...
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PMID: 15228548
PDF is available here.
Abstract
Rinderpest was such a devastating disease throughout Africa, Asia and Europe, capable of shaping the destinies of governments as well as the livelihoods of producers and consumers alike, that all sectors of society demanded that scientists should strive to develop a means of protecting cattle agains...
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PMID: 15742620
PDF is available here.
Abstract
A panel of monoclonal antibodies (mAbs) was generated against the RBOK strain of rinderpest virus (RPV). All of them bound to the N protein of RPV. The antigen capture ELISA using the mAbs could detect the virus in crude viral preparations. The mAb 12BF8.1.1 showed higher reactivity with cell-associ...
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PMID: 14979554
PDF is available here.
Abstract
This paper describes an objective system of monitoring the performance of disease surveillance. The system was developed through dialogue with a number of countries in Africa and adopted as part of the Global Rinderpest Eradication Programme of the Food and Agriculture Organization of the United Nat...
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PMID: 15005541
PDF is available here.
Abstract
An experimental competitive enzyme-linked immunosorbent assay (morbillivirus cELISA) using a recombinant N antigen (rRPV N) expressed in a baculovirus and a ruminant morbillivirus (RPV and PPRV)-specific monoclonal antibody (P-13A9) was developed for simultaneous detection of rinderpest virus (RPV)...
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PMID: 14516703
PDF is available here.
Abstract
In 1994, rinderpest virus of African lineage 2 was detected in East Africa after an apparent absence of more than 30 years. In 1996, a disease search, based on participatory epidemiological techniques supplemented by serological and virological analyses, was undertaken in southern Somalia and north-...
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PMID: 12790233
PDF is available here.
Abstract
We report on an epidemiological assessment of surveillance and control of rinderpest (RP) in Uganda between 1990 and 1998. Active data were collected by administration of questionnaires to animal health personnel and their auxiliaries and to stockowners in six selected districts of eastern and north...
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PMID: 12507853
PDF is available here.
T T Yilma,
F F Aziz,
S S Ahmad,
L L Jones,
R R Ngotho,
H H Wamwayi,
B B Beyene,
M M Yesus,
B B Egziabher,
M M Diop,
J J Sarr and
P P Verardi
Abstract
We previously reported the development of first- and second-generation recombinant vaccinia virus vaccines which provide complete protection against rinderpest virus (RPV) and peste-des-petits ruminants virus (PPRV). These vaccines are safe even for immunodeficient mice and macaques with acquired im...
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PMID: 14677681
PDF is available here.
Abstract
We describe different approaches we have taken to produce such a vaccine using reverse genetics to add a marker to the existing and widely used Plowright rinderpest vaccine....
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PMID: 14677680
PDF is available here.
Abstract
Rinderpest, also known as cattle plague, was for centuries the most dreaded bovine plague known and one that changed the course of history and still seriously compromises trade. It can lay waste not only to farming communities but the wildlife heritage of countries also is threatened because its bro...
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PMID: 12442581
PDF is available here.
W P Taylor,
P L Roeder,
M M Rweyemamu,
J N Melewas,
P Majuva,
R T Kimaro,
J N Mollel,
B J Mtei,
P Wambura,
J Anderson,
P B Rossiter,
R Kock,
T Melengeya and
R Van den Ende
Abstract
In January 1997, Tanzania requested international assistance against rinderpest on the grounds that the virus had probably entered the country from southern Kenya. Over the next few months, a variety of attempts were made to determine the extent of the incursion by searching for serological and clin...
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PMID: 12537386
PDF is available here.
Abstract
Forging a scientific career in 19th-century Britain was difficult for most middle-class scientists. Despite his discovery of thallium in 1861 and later distinction as an experimental physicist that led him to the Presidency of the Royal Society (1913-1915), William Crookes (1832-1919) never obtained...
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PMID: 12369466
PDF is available here.
Abstract
These results suggest that, in addition to oncosis, apoptotic cellular death in lymphatic tissues contributes substantially to the pathogenesis of rinderpest....
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PMID: 12354541
PDF is available here.
Abstract
We used a recombinant strain of Rinderpest virus (RPV) to examine the role of this protein in determining the ability of RPV to replicate in rabbits. The recombinant was based on the RBOK vaccine strain, which is avirulent in rabbits, carrying the haemagglutinin (H) protein gene from the lapinized R...
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PMID: 12029161
PDF is available here.
Abstract
These results indicate that capripoxvirus is a suitable vector for the development of safe, effective and stable recombinant vaccines for cattle....
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PMID: 12002554
PDF is available here.
Abstract
Plasmid vaccine pBK-CMVMPILC113 expressing the matrix (M) gene of rinderpest virus was assessed for its potential to protect rabbits against a lethal viral challenge. Rabbits immunized with plasmids expressing the M gene were not protected when challenged with lapinized rinderpest virus, despite the...
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PMID: 12090294
PDF is available here.
Abstract
Rinderpest virus haemagglutinin (H) protein was expressed in eukaryotic cells and the plasmid encoding H gene was used for immunization of rabbits. The immunized rabbits were completely protected from lethal challenge with virulent lapinized rinderpest virus. Similar results were also observed in ra...
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PMID: 11958458
PDF is available here.
Abstract
We assessed whether RPV and PPRV have the potential to be neurovirulent. We describe the outcome of infection, of selected mouse strains, with isolates of RPV, PPRV, PDV, porpoise morbillivirus (PMV), dolphin morbillivirus (DMV), and a wild-type strain of MV. In the case of RPV virus, strains with d...
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PMID: 11847591
PDF is available here.
Abstract
These results suggest that epitopes at residues 383 to 387 and 587 to 592 may be immunodominant in humoral immunity to RPV infection....
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PMID: 11799164
PDF is available here.
Abstract
The author describes the activity of the British veterinary services and especially the vaccination against rinderpest in Tanganyika in the years after the Second World War as seen by late Ken Aspinall (1922-1996).
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PMID: 12146507
PDF is available here.
Abstract
We have constructed a recombinant vaccinia virus vaccine (v2RVFH) that expresses both the fusion (F) and hemagglutinin (H) genes of rinderpest virus (RPV) under strong synthetic vaccinia virus promoters. v2RVFH-infected cells express high levels of the F and H glycoproteins and show extensive syncyt...
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PMID: 11752138
PDF is available here.
Abstract
Wildlife mortality involving bongos, Tragelaphus eurycerus, and other ungulates was investigated in the north of the Congo Republic in 1997. Four bongos, one forest buffalo, Syncerus caffer nanus, and one domestic sheep were examined and sampled. Although an outbreak of rinderpest had been suspected...
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PMID: 12026060
PDF is available here.
Abstract
Rinderpest had been reported in most parts of Ethiopia when the Pan African Rinderpest Campaign (PARC) was launched. As a result of intensive disease investigation and strategic vaccination, most parts of the country are now considered provisionally free, and widespread vaccination has been replaced...
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PMID: 11556621
PDF is available here.
Abstract
We have reported the generation of a recombinant baculovirus expressing H protein and studied its protective properties in cattle. In this report, we demonstrate that the recombinant baculovirus encoded H protein expressed in insect cells gets incorporated into extracellular baculovirus. Single admi...
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PMID: 11427260
PDF is available here.
Abstract
The nucleotide sequence of the matrixprotein (M) gene of the lapinized rinderpest virus (RPV-L) was determined. The full-length cDNA of the RPV-L M gene is composed of 1460 base pairs and is supposed to contain an open reading frame of 1005 nucleotides encoding on M protein of 335 amino acids. The h...
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PMID: 11503909
PDF is available here.
Abstract
These results indicate that this ISCOM vaccine is effective in producing protective immunity in cattle and should be a suitable means of delivering glycoprotein antigens from other morbilliviruses....
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PMID: 11348698
PDF is available here.