Abstract
A retrospective study was performed to characterize 64 cases of anal sac gland carcinoma (ASGC) in cats. All ASGCs diagnosed between 1995 and 2007 at a private diagnostic laboratory in the UK were reviewed. Apocrine gland origin was confirmed in a subset of these tumors by immunohistochemistry and t...
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PMID: 19276061
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Abstract
Stained cytological specimens from 7 canine anal sac gland adenomas and 11 canine anal sac gland carcinomas were analyzed by computer-assisted nuclear morphometry. In each case, the nuclei of at least 100 neoplastic cells were measured, and the mean nuclear area (MNA), mean nuclear perimeter (MNP),...
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PMID: 18457852
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Abstract
A computational investigation of the sulfur-containing heterocyclic components (substituted thietanes and 1,2-dithiolanes) of Mustela anal sac secretions has been carried out. A cluster analysis of the chemical compositions of Mustela anal sac volatiles reveals little similarity with established phy...
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PMID: 18626668
PDF is available here.
Abstract
A seven-year-old, neutered male ferret was referred to our hospital with two perianal masses (2.4x3.0 and 2.4x3.5 cm, respectively) that had recurred after initial surgical excision. Complete resection of the masses was impossible as there was deep invasion along the rectum. On histopathology, the m...
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PMID: 18631226
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Abstract
This study was conducted to characterize the gross and cytological characteristics of secretions from normal feline anal sacs. Thirty cats with no recent history of anal-sac disease were selected consecutively and their anal sacs manually expressed. The color, cell counts, or presence of solid porti...
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PMID: 18282777
PDF is available here.
Abstract
Two experiments were designed to determine the efficacy of intraglandular antibiotic treatment in beef bulls. Experiment 1 was designed to evaluate the glandular tissue reaction to intraglandular antibiotic treatment. Experiment 2 was conducted to determine the efficacy intraglandular injection of a...
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PMID: 17399921
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Abstract
We describe the successful treatment of an incompletely excised ASGC by using cisplatin selectively driven within the tumor cells by trains of biphasic pulses. The dog received two courses of electrochemotherapy 14 days apart. Neither systemic nor local toxicities were detected during the whole cour...
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PMID: 18396781
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Abstract
Retrospective evaluation revealed 4 statistically significant negative prognostic indicators for survival: lack of therapy, presence of distant metastases, presence of lymph node metastases, and primary tumor size. Lymph node extirpation was a statistically significant positive prognostic indicator...
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PMID: 17427388
PDF is available here.
Abstract
The plasma concentrations of total calcium, ionised calcium, albumin, parathyroid hormone and parathyroid hormone-related protein (PTHrp) were measured in 25 dogs with lymphoma, nine dogs with primary hyperparathyroidism and seven dogs with adenocarcinoma of the apocrine gland of the anal sac. Plasm...
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PMID: 17172477
PDF is available here.
Abstract
Both immunosuppressive protocols were effective in reducing progression of AF. Subsequent draining tracts excision, cryptectomy, and anal sacculectomy were bilateral (12 dogs) or unilateral (13 dogs of which 4 had bilateral anal sacculectomy). Postoperative recovery was uneventful, except for 2 dogs...
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PMID: 17187638
PDF is available here.
Abstract
In the current study, the use of spraints for monitoring levels of polychlorinated biphenyls (PCBs) in individual otters was experimentally validated. On the basis of a detailed pattern analysis, it is concluded that in the current study, PCB concentrations in spraints that contain relatively high c...
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PMID: 17089702
PDF is available here.
Abstract
A perianal mass in a 15-year-old domestic shorthair cat with a history of a firm, painful swelling in the left ventrolateral perianal region was surgically excised and submitted for light microscopic evaluation. Histologically, this was a poorly demarcated, unencapsulated, multilobulated neoplasm th...
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PMID: 17099161
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Abstract
No surgical complications occurred. Three dogs were euthanatized; median survival, 20.6 months. One dog was alive for 19 months postoperatively. One dog had 5 sequential surgical procedures: 1 iliac lymphadenectomy and 4 debulking procedures of metastatic neoplastic tissue around and dorsal to the i...
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PMID: 16635006
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Abstract
Forty-eight dogs were eligible for post-operative follow-up 1.5 to 36 (mean 17.4, median 18) months after surgery. Lesion recurrence, faecal incontinence and stricture formation occurred in 2%, 4% and 13% of dogs, respectively. The percentage of dogs considered by their owners to have an acceptable...
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PMID: 16528387
PDF is available here.
Abstract
Dichloromethane extracts of wolverine (Gulo gulo, Mustelinae, Mustelidae) anal gland secretion were examined by gas chromatography-mass spectrometry. The secretion composition was complex and variable for the six samples examined: 123 compounds were detected in total, with the number per animal rang...
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PMID: 16132215
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Abstract
A retrospective study of anal sac tumours without pulmonary metastases, from the author's clinical records for the period July 1989 to July 2002, was conducted to establish the response to treatment with surgery and melphalan chemotherapy. Of 21 dogs with tumours of the anal sacs 19 had apocrine gla...
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PMID: 15986909
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Abstract
A 4-year old, female spayed terrier was referred for hind end paresis that rapidly progressed to paralysis. Spinal radiographs revealed vertebral collapse and bony lysis. Myelography confirmed spinal cord compression and surgical exploration found an extradural soft tissue mass. Metastatic anal sac...
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PMID: 15368742
PDF is available here.
Abstract
We show directly that volatile anal scent gland odourants from male and female ferrets activated overlapping but distinguishable clusters of glomeruli located in the ventral-caudal portion of the main olfactory bulb (MOB) of breeding ferrets of both sexes. No glomerular activation was seen in the ac...
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PMID: 15305871
PDF is available here.
Abstract
A study was conducted to characterize the gross and cytological characteristics of secretions from normal canine anal sacs. Fifty dogs with no recent history of anal-sac disease were selected consecutively and their anal sacs manually expressed. Of the 47 dogs with known or estimated ages, 27 were <...
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PMID: 15315705
PDF is available here.
Abstract
We hypothesized that enzymes in the oral and anal secretions of the subfamily Nicrophorinae would inhibit bacterial growth, while secretions from the subfamily Silphinae would not. The secretions were assayed for inhibitory effects with a Microtox Analyzer that monitors the decrease in bioluminescen...
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PMID: 15260219
PDF is available here.
Abstract
Sixty-one medial iliac lymph nodes of 38 different dogs (eight with adenocarcinoma of the apocrine glands of the anal sac, 13 with multicentric lymphoma, six with multicentric lymphoma but in clinical remission, and 11 control dogs) were evaluated to assess the ability of ultrasound to identify and...
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PMID: 15072149
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Abstract
A 13-year-old dog was diagnosed with hypercalcemia of malignancy associated with adenocarcinoma of the anal sacs. Hypercalcemia was treated with intravenous (IV) 0.9% sodium chloride (NaCl), furosemide, calcitonin, and pamidronate. Hypomagnesemia was documented by 72 hours following a single, IV dos...
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PMID: 14736909
PDF is available here.
Abstract
Sex distribution was approximately equal (54% female, 46% male). One hundred four dogs underwent treatment consisting of surgery, radiation therapy, chemotherapy, or multimodal treatment. Median survival for treated dogs was 544 days (range, 0 to 1,873 days). Dogs treated with chemotherapy alone had...
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PMID: 14507100
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Abstract
We found eight new compounds in the two sympatric Mustela species, M. eversmanni and M. sibirica. These compounds had not been detected by headspace sampling with solvent desorption. Two of the newly detected compounds are nitrogen-containing compounds, indole and o-aminoacetophenone and the remaini...
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PMID: 12826534
PDF is available here.
Abstract
Tumors of the perianal area of dogs are common and include multiple tumor types. Whereas perianal adenomas occur often, adenocarcinomas of the apocrine glands of the anal sac occur less frequently. A review of the literature revealed no reports of squamous cell carcinomas arising from the epithelial...
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PMID: 12724576
PDF is available here.
Abstract
Our histological description of the fourth type of mammalian skin glands--hepatiod glands--allowed us to revise the obtained and published data mistaking the alveolar glands of the anal sacs in cats and the limb glands in deers as sebaceous. Large clusters of hepatiod glands were discovered in the a...
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PMID: 12942753
PDF is available here.
Abstract
Seventeen dogs satisfied the selection criteria. The physical characteristics of the exudate and sac varied, though 31/34 sacs were empty or soft, 22/27 exudates were light or dark brown and 19/27 exudates were a thin liquid. Total leucocyte, keratinocyte and bacilli counts were extremely variable....
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PMID: 15084008
PDF is available here.
Abstract
A 12-year-old male neutered Siamese cat presented with a history of inappetance and lethargy and an enlarged left anal sac. The anal sac was surgically excised and histopathology confirmed the diagnosis of anal sac adenocarcinoma. Perianal tumours are rare in the cat and anal sac adenocarcinoma has...
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PMID: 12468314
PDF is available here.
Abstract
Macroscopic and cytological aspects of anal sac content were evaluated in 40 normal dogs and 10 dogs each with pyoderma, Malassezia dermatitis associated with atopic dermatitis and uncomplicated atopic dermatitis. Bacteria isolated from anal sacs were compared with those from abdominal skin and hair...
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PMID: 12464064
PDF is available here.
Abstract
This article deals with the cytologic appearance of various glandular tissues located in the subcutaneous tissues. Normal cytologic features are described. In addition, inflammatory, infectious, neoplastic, and hyperplastic changes are discussed. Most of these features are depicted in the 60+ photom...
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PMID: 12469494
PDF is available here.
Abstract
GC-MS analysis of the anal sac secretion from the hooded skunk, Mephitis macroura, showed the following seven major components comprised 99% of the volatiles in this secretion: (E)-2-butene-1-thiol, 3-methyl-1-butanethiol, S-(E)-2-butenyl thioacetate, S-3-methylbutenyl thioacetate, 2-phenylethanethi...
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PMID: 12449512
PDF is available here.
Abstract
In 57 dogs, a closed technique was used, and in 38, an open technique was used. Only 3 dogs developed short-term complications (excessive drainage, scooting and inflammation, and seroma formation), and 14 developed long-term complications (continued licking of the surgery site, fecal incontinence, f...
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PMID: 12216905
PDF is available here.
Abstract
We conclude that platinum chemotherapy has antitumor activity in canine apocrine gland carcinoma and that further study of these agents is warranted....
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PMID: 11822797
PDF is available here.
Abstract
A 13-year-old castrated male Bassett Hound was examined because of a 2-week history of severe constipation and tenesmus. Radiography revealed a large cystic mass in the caudal portion of the abdomen that was compressing the urethra and obstructing the pelvic canal. A small perianal mass was also not...
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PMID: 11767923
PDF is available here.
Abstract
The study reports on secretion production and composition in the tubular glands of the canine anal sacs. For this purpose, light and electron microscopical (TEM, SEM) as well as several histochemical methods for the demonstration of lysosomal acidity, lipofuscin, and complex carbohydrates were used....
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PMID: 11173805
PDF is available here.
Abstract
This article describes the most common extra-abdominal surgeries performed in ferrets, including anal sacculectomy for descenting, mammary and prepucial adenoma or adenocarcinoma removal, chordomas, and perineal urethrostomy. Thoracotomy and special considerations for performing surgery on ferrets a...
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PMID: 11228924
PDF is available here.
Abstract
Circulating parathyroid hormone-related protein (PTHrP) is the primary humoral factor in dogs with spontaneous humoral hypercalcemia of malignancy (HHM) and adenocarcinomas derived from apocrine glands of the anal sac. A canine apocrine adenocarcinoma model of HHM in nude mice (CAC-8) was developed...
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PMID: 9754539
PDF is available here.
Abstract
Chronic anal sac infection or impaction can be a frustrating problem for both the dog owner and veterinarian. Anal sacculectomy may be used to resolve clinical signs when medical management fails. Four dogs, ranging in size from 6 kg to 34 kg, were treated with closed anal sacculectomies, in which t...
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PMID: 9728470
PDF is available here.
Abstract
Conventional methods have been used to study the general configuration of the wall of the Sinus paranalis in dogs. Apocrine tubular glands, elastic fibres and smooth-muscle fibres are the more significant elements of the wall, together with the epithelium and connective tissue. By means of the immun...
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PMID: 8644934
PDF is available here.
Abstract
The geometric mean Fel d I concentration was 41 U/g secretion which represents 3.4% of the total protein levels. This amount is the highest ever reported in cat tissues or secretions. CONCLUSION: The close association of Fel d I protein with skin sebaceous glands and anal sacs both with holocrine fu...
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PMID: 8835125
PDF is available here.
Abstract
The blood vessels of the anal sac in the domestic cat--A. rectalis caudalis and A. perinealis ventralis, from which the former arises--are visceral blood vessels. A rectalis caudalis, being the origin of anal sac arteries, facilitates the blood supply of the anal sac, while the duct of the anal sac...
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PMID: 7645737
PDF is available here.
Abstract
The literature about the anal sacs of healthy dogs and the pathogenesis, diagnosis and therapy of anal sac impaction and sacculitis are reviewed. Knowledge about the physiological role of the anal sacs is still confusing. The colour and consistency of the anal sac contents are variable in healthy do...
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PMID: 7815780
PDF is available here.
Abstract
We were unable to detect 2-phenylethylamine. The anal sac secretion was found to have a similar amine content....
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PMID: 1388518
PDF is available here.
Abstract
A 15-year-old dog was evaluated for a nonresponsive generalized pruritic condition of 5 months duration. Routine diagnostic testing, including intradermal testing with 63 inhaled allergens and the feeding of a home-cooked hypoallergenic diet, failed to define the cause of the pruritus. An intraderma...
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PMID: 1954743
PDF is available here.
Abstract
The presence of parathyroid hormone-related protein (PTHrP) in the apocrine adenocarcinoma tumor line (CAC-8) derived from a hypercalcemic dog was demonstrated by western and northern blot analyses. Western blots of CAC-8 tumor extracts revealed a major protein with a molecular weight of approximate...
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PMID: 2345942
PDF is available here.
Abstract
The epithelial coating of the rectal pouch and fistula was studied morphologically in 33 newborn piglets with high and low forms of anal atresia and was found to be similar to the epithelial coating of the anal canal in normal piglets: the typical epithelium of the rectum changed its character into...
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PMID: 2718639
PDF is available here.
Abstract
The problems associated with perineal surgery depend on the surgical procedure performed. Problems are encountered before, during, and after surgery. Appropriate preoperative assessment, proper surgical technique, and thorough postoperative management are required for successful results. Immediate r...
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PMID: 2520111
PDF is available here.
Abstract
Out of 87 opossums, Didelphis albiventris, captured in the Bambuí area (Minas Gerais State), 32 (36.7%) were found infected by Trypanosoma cruzi; the rates varied according to whether the specimens originated from sylvan, rural peridomiciliar or urban surroundings, being 34.9, 81.8 and 7.7 respecti...
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PMID: 2108308
PDF is available here.