Find your PDFs fast.
Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Harderian Gland (0):
Recent article
Harderian Gland
Methods in Enzymology (452)452 2009
Abstract
Our results show different autophagy mechanisms in Syrian hamster HG, macroautophagy and other lysosomal-like processes such as chaperone-mediated autophagy, depending on sex and probably related to oxidative stress status. This chapter describes the methods used by us to characterize the autophagic...
|
PMID: 19200898
PDF is available here.
PDF is available here.
| < More recent | Older article > |
Abstract
The mouse aldehyde oxidase AOH2 (aldehyde oxidase homolog 2) is a molybdoflavoenzyme. Harderian glands are the richest source of AOH2, although the protein is detectable also in sebaceous glands, epidermis, and other keratinized epithelia. The levels of AOH2 in the Harderian gland and skin are contr...
|
PMID: 18981221
PDF is available here.
PDF is available here.
Avian Diseases (52)4 2008
Abstract
We compared detection of infectious bronchitis virus (IBV) by quantitative RT-PCR (qRT-PCR) in tears and trachea of IBV-infected chickens and found that quantitative detection of IBV RNA in tears is more sensitive than in tracheal homogenates. Furthermore, we demonstrated that IBV contained in chick...
|
PMID: 19166051
PDF is available here.
PDF is available here.
Abstract
We found that in primary culture of male hamster Harderian gland (HG), androgens (A) increase the MHG07 (male Harderian gland) expression and this effect is abrogated by both flutamide and cycloheximide. The present study represents a deeper analysis on MHG07 regulation by other members of steroid/t...
|
PMID: 18848890
PDF is available here.
PDF is available here.
Abstract
We report here that the HG contains an extremely high level of PPIX, 630- to 670-fold higher than in the liver, without a day-night difference, which is the consequence of both low Fech gene expression (5- to 7-fold lower than in the liver) and ALA-S over-expression (4- to 7-fold higher in the HG th...
|
PMID: 19005892
PDF is available here.
PDF is available here.
Veterinary Pathology (45)3 2008
Abstract
Harderian gland neoplasms were identified in 18 aged, adult Beechey ground squirrels (Spermophilus beecheyi) from the records of 167 wild-caught captive animals that were necropsied. All but one animal had tumors that were classified as carcinomas, with infiltrative growth and frequent metastases. T...
|
PMID: 18487500
PDF is available here.
PDF is available here.
Abstract
We found a marked sexual dichotomy in the expression of uncoupling protein-3 (UCP3), a mitochondrial protein carrier, that probably exports fatty acid anions and fatty acid peroxides from the mitochondrial matrix. Following castration and/or testosterone treatment: (1) UCP3 levels correlated with th...
|
PMID: 18247364
PDF is available here.
PDF is available here.
Journal of Experimental Biology (211)Pt 4 2008
Abstract
The secretory activity of the Harderian gland (HG) is influenced by both exogenous (such as light and temperature) and endogenous (such as prolactin, thyroid hormones and steroid hormones) factors, which vary among species. In the present study, the effects of hypothyroidism on the rat HG were exami...
|
PMID: 18245638
PDF is available here.
PDF is available here.
Abstract
We conducted a pilot study of unilateral harderian gland adenectomy, leaving the contralateral gland intact for comparison. At 1 wk after surgery, each rat was injected intravenously with 18F-FDG, and 40 min later underwent brain microPET for 20 min. Review of the resulting images showed that the fr...
|
PMID: 17877327
PDF is available here.
PDF is available here.
Tissue & Cell (39)3 2007
Abstract
These results suggested that the Harderian gland, even though it is not a lymphoid organ as a whole, but acts as an immunopotent organ in chickens, and that the gland in native chicken contains more Ig-containing plasma cells due to their scavenging....
|
PMID: 17445851
PDF is available here.
PDF is available here.
Abstract
We have previously shown that mice with a deficiency in the ABC transporter Bcrp1/Abcg2 display a novel type of protoporphyria. This protoporphyria is mild compared with ferrochelatase-dependent EPP, and in itself not sufficient to cause phototoxicity, but it might exacerbate the consequences of oth...
|
PMID: 17314268
PDF is available here.
PDF is available here.
Abstract
We observed both types of vesicles in both types of cells they differed, principally, in quantity. The glands also possessed prominent duct systems, with three orders of complexity. The dolphin orbital HG appears to function as a mixed heterologous gland with two types of cells that exhibit both typ...
|
PMID: 17535354
PDF is available here.
PDF is available here.
Abstract
This first in-vivo study of rat dopamine transporter binding after pre-treatment with various doses of methylphenidate showed a dose-dependent reduction of striatal dopamine transporter binding. Results indicate that in-vivo quantification of dopamine transporter binding is feasible with I-FP-CIT an...
|
PMID: 17264780
PDF is available here.
PDF is available here.
Toxicological Sciences (95)2 2007
Abstract
Urethane is an established animal carcinogen and has been classified as "reasonably anticipated to be a human carcinogen." Until recently, urethane metabolism via esterase was considered the main metabolic pathway of this chemical. However, recent studies in this laboratory showed that CYP2E1, and n...
|
PMID: 17093202
PDF is available here.
PDF is available here.
Abstract
We examined the organogenesis and histochemistry of the anterior orbital glandular mass in two species of deer (Muntiacus reevesi and Dama dama) to determine whether it comprises two distinct glands or one bilobed gland. The anterior orbital regions of 30 fetal specimens of both species, along with...
|
PMID: 17910397
PDF is available here.
PDF is available here.
Abstract
We review the historical context of Harder's discovery, and provide Harder's original Latin text as well as an English translation....
|
PMID: 17910396
PDF is available here.
PDF is available here.
Poultry Science (86)1 2007
Abstract
The comparative histopathology of 2 different strains of infectious bronchitis virus (T and N1/ 88) in vaccinated hens was studied at 110 wk of age. The Harderian gland showed similar histopathology in T- and N1/88-infected hens. The trachea and kidney of challenged vaccinated hens were protected to...
|
PMID: 17179416
PDF is available here.
PDF is available here.
Poultry Science (86)1 2007
Abstract
The comparative and sequential histopathology of different tissues of unvaccinated laying hens and cockerels were studied in chickens exposed to T and N1/88 strain of infectious bronchitis virus (IBV). The Harderian gland and trachea of hens and cockerels in both T- and N1/88-infected groups were da...
|
PMID: 17179415
PDF is available here.
PDF is available here.
Toxicologic Pathology (35)1 2007
Abstract
We evaluated representative EO-induced and equivalent spontaneous neoplasms for K-ras mutations in codons 12, 13, and 61. K-ras mutations were identified in 100% (23/23) of the EO-induced lung neoplasms and 25% (27/108) of the spontaneous lung neoplasms. Codon 12 G to T transversions were common in...
|
PMID: 17325976
PDF is available here.
PDF is available here.
Journal of Anatomy (209)5 2006
Abstract
We also characterized the Harderian gland. MRI was performed at 1.5 T in anaesthetized piglets (n = 10, 12-36 h of age). Magnetic resonance perfusion and diffusion imaging were performed at different time points, before, during and after the induction of hypoxia-ischaemia. The effects following bila...
|
PMID: 17062026
PDF is available here.
PDF is available here.
Abstract
We investigated the occurrence and characterized intraepithelial plasma cells in the Harderian gland of ducks, according to the immunoglobulin produced. Numerous intraepithelial plasma cells were found confined to the Harderian gland ducts. Plasma cells were also found in the ducts lamina propria. I...
|
PMID: 16806495
PDF is available here.
PDF is available here.
Abstract
The X-ray structure of the tetragonal form of apo acyl-CoA-binding protein (ACBP) from the Harderian gland of the South American armadillo Chaetophractus villosus has been solved. ACBP is a carrier for activated long-chain fatty acids and has been associated with many aspects of lipid metabolism. It...
|
PMID: 17012783
PDF is available here.
PDF is available here.
Abstract
We found that highest accumulations of exogenous D-Asp in HGs occurred 15 hr after the injection. Specifically, exogenous D-Asp prevalently stimulated serous secretion from the lateral portion of the gland, where immunohistochemical analysis revealed a major accumulation. Similarly, in the medial pa...
|
PMID: 16721806
PDF is available here.
PDF is available here.
Abstract
The Harderian gland, an anterior orbital structure, is either absent or vestigial in primates. This is based upon gross anatomical observations of scattered adult specimens. Though largely absent in the adult human, it is present in the fetal and neonatal stages. Thus, histological examination of th...
|
PMID: 16856596
PDF is available here.
PDF is available here.
Abstract
We herein present a protein reference database of the rat Harderian gland that may serve as analytical tool for future proteomic work, report lipid and porphyrin handling cascades, address sequence conflicts and report structures that have not been so far described by proteomics methods....
|
PMID: 16823983
PDF is available here.
PDF is available here.
Abstract
We studied in Spalax the oxidative status of the Harderian gland (HG), an organ which is particularly vulnerable to oxidative stress in many rodents. With regard to the sexual dimorphism found in this gland, differences between males and females were determined and compared to the surface-dwelling S...
|
PMID: 16479405
PDF is available here.
PDF is available here.
Abstract
We expressed a mutant form of Calpha, L309A, in brain and Harderian (lacrimal) gland of transgenic mice. We found an altered recruitment of regulatory subunits into the complex, demonstrating a role for the carboxyterminal leucine of Calpha in regulating holoenzyme assembly in vivo. This was associa...
|
PMID: 16580638
PDF is available here.
PDF is available here.
Mechanisms of Development (123)5 2006
Abstract
We expressed an L309A mutant catalytic subunit in Harderian gland of transgenic mice. We found a delayed postnatal development and hypoplasia of the gland, causing enophthalmos. To determine why expression of the L309A mutant caused this phenotype, we determined the PP2A subunit composition. We foun...
|
PMID: 16679006
PDF is available here.
PDF is available here.
Journal of Endocrinology (189)1 2006
Abstract
We isolated cDNA for ferrochelatase from hamster liver, using the 5'- and 3'- rapid amplification of complementary DNA ends (RACE), and investigated its expression in HG from males and females. The full-length cDNA comprises an open reading frame of 1269 bp encoding a polypeptide of 422 amino-acid r...
|
PMID: 16614385
PDF is available here.
PDF is available here.
Abstract
We have recently showed that autophagic processes are in the Syrian hamster HG as the first result of an elevated porphyrin metabolism observed in both sexes. In this case, autophagy is not a cell death mechanism per se but a constant renovation system which allows to continuing with the normal glan...
|
PMID: 16874050
PDF is available here.
PDF is available here.
Abstract
The Harderian gland (HG), a sero-mucous secreting organ in the eye orbit, has long been recognized as immunologically important in chickens. During experimentation to characterize immune components of the gland, proteomics analysis revealed the presence of hematopoietic prostaglandin D synthase (H-P...
|
PMID: 16046238
PDF is available here.
PDF is available here.
Journal of Morphology (266)3 2005
Abstract
We examined the lacrimal apparatus of several specimens of Alligator mississippiensis anatomically, histologically, and histochemically and studied the embryogenesis of this system. The nasolacrimal duct possesses a distal secretory area, which is more convoluted than that of typical mammals or lepi...
|
PMID: 16163706
PDF is available here.
PDF is available here.
Abstract
More than 30 years ago it was reported that rodent Harderian glands contained a tricarboxylic acid porphyrin, which the authors named Harderoporphyrin. The recent finding in rat Harderian glands of the porphyrin glycoconjugate, protoporphyrin-1-O-acyl-beta-xyloside as a major component led to scruti...
|
PMID: 15678522
PDF is available here.
PDF is available here.
Abstract
We have found that autophagic processes are the first result of an elevated porphyrin metabolism, as it is observed in both sexes. This mechanism is considered, in this case, as a constant renovation system that allows the normal gland activity to be sustained. Furthermore, there is a second procedu...
|
PMID: 16186173
PDF is available here.
PDF is available here.
Abstract
In 1997, three lines of inbred Peromyscus leucopus--GS109A, GS16A1, and GS16B--were acquired by the Peromyscus Genetic Stock Center. Since then, records have been kept on tumors detected by visible inspection of live animals. The inbred lines GS109A and GS16A1 presented tumors with frequencies subst...
|
PMID: 16158914
PDF is available here.
PDF is available here.
Abstract
Melatonin acts through several specific receptors, including membrane receptors (MT(1) and MT(2)) and members of the RZR/ROR nuclear receptors family, which have been identified in a large variety of mammalian and nonmammalian cells types. Both membrane and nuclear melatonin receptors have been part...
|
PMID: 15978053
PDF is available here.
PDF is available here.
Abstract
Our in vivo experiments, consisting of i.p. injection of 2.0 mumol/g b.w. D-Asp in frogs collected during two periods of differing glandular activity (high or medium-low secretory activity), revealed that HG can to take up and accumulate D-Asp and that this amino acid may modulate the exocrine secre...
|
PMID: 15744756
PDF is available here.
PDF is available here.
Anatomy and Embryology (209)5 2005
Abstract
The anatomical, histological, histochemical and ultrastructural characteristics of the Harderian gland of the armadillo Chaetophractus villosus were described. The gland is the largest structure in the bony orbit. It is situated in the anteroventral region of the orbit. Obvious structural difference...
|
PMID: 15883851
PDF is available here.
PDF is available here.
Life Sciences (76)20 2005
Abstract
The effects of ghrelin, a peptide hormone secreted from the stomach, on melatonin remain unknown. The aim of the study was to investigate possible ghrelin-melatonin interactions by studying the effect of ghrelin treatment on melatonin production in rat pineal and Harderian glands. Young (9 weeks) an...
|
PMID: 15748632
PDF is available here.
PDF is available here.
Abstract
A 22-month-old, female rabbit was presented with a 1-day history of acute unilateral exophthalmos. Ultrasonography and computed tomography (CT) of the orbit revealed an orbital mass. Retrobulbar lymphoma was diagnosed following fine-needle aspiration biopsy (FNAB). Thoracic radiographs were normal,...
|
PMID: 16008706
PDF is available here.
PDF is available here.
Abstract
The purpose of the study was to support of the International Life Sciences Institute (ILSI) alternative carcinogenicity models initiative to evaluate the carcinogenic potential of the nongenotoxic carcinogen, clofibrate, a peroxisome proliferator-activated receptor (PPAR) alpha agonist, following or...
|
PMID: 16257850
PDF is available here.
PDF is available here.
Avian Diseases (48)3 2004
Abstract
The events during the pathogenesis of chicken anemia virus (CAV) infection following intramuscular (IM) and oral inoculation were further elucidated and compared by sequential clinical, pathologic, and morphometric histopathologic evaluations, and by sequential determination of CAV genome concentrat...
|
PMID: 15529971
PDF is available here.
PDF is available here.
Abstract
Standard methods for risk assessments resulting from human exposures to mixed radiation fields in Space consisting of different particle types and energies rely upon quality factors. These are generally defined as a function of linear energy transfer (LET) and are assumed to be proportional to the r...
|
PMID: 15446807
PDF is available here.
PDF is available here.
Endocrinology (145)7 2004
Abstract
The effects of T(3) administration on the rat Harderian gland were examined at morphological, biochemical, and molecular levels. T(3) induced hypertrophy of the two cell types (A and B) present in the glandular epithelium. In type A cells, the hypertrophy was mainly due to an increase in the size of...
|
PMID: 15064282
PDF is available here.
PDF is available here.
Abstract
I and type II. These cells contain dense secretory vesicles in their cytoplasm and they are connected laterally with desmosomes. At the basal site of these cells, myoepithelial cells are present. Plasma cells are observed in the subepithelial region of the gland. In the interlobular trabeculae, form...
|
PMID: 15144280
PDF is available here.
PDF is available here.
Abstract
The blind subterranean mole rat superspecies Spalax ehrenbergi is an extreme example of mammalian adaptation to life underground. Though this rodent is totally visually blind, harboring a drastically degenerated subcutaneous rudimentary eye, its daily activity rhythm is entrainable to LD cycles. Thi...
|
PMID: 14964701
PDF is available here.
PDF is available here.
Abstract
We examined the effect of hypoxic ischemia and hypoxia vs. normoxia on postnatal murine brain substrate transporter concentrations and function. We detected a transient increase in the neuronal brain glucose transporter isoform (GLUT-3) in response to hypoxic ischemia after 4 h of reoxygenation. Thi...
|
PMID: 14525722
PDF is available here.
PDF is available here.
Abstract
Reversed-phase TLC systems using ion-pairing reagents are described for the separation without prior derivatization of the porphyrins of rat Harderian gland. Porphyrins with R(f) values greater than protoporphyrin but smaller than coproporphyrin, representing harderoporphyrin, were labile to 1 m NaO...
|
PMID: 14648610
PDF is available here.
PDF is available here.
Abstract
It was found that when Fura-2-loaded cells were excited by light at 340/380 nm, [Ca2+]c increased spontaneously, indicating a photodynamic action powered by light at 340/380 nm. In contrast, with the visible spectrum calcium probe Fluo-3 (lambda(ex) = 475 nm), carbachol at 10 microm induced [Ca2+]c...
|
PMID: 14510778
PDF is available here.
PDF is available here.
Abstract
Dorsal lacrimal glands, superior glands of the third eyelid and Harderian glands (deep gland of the third eyelid) from 19 bison and 18 cattle free of apparent ocular disease were examined to compare the normal anatomical properties of these glands. All glands were characterized and measured (length...
|
PMID: 12969024
PDF is available here.
PDF is available here.
Transgenic Research (12)3 2003
Abstract
We established two lines of transgenic rats carrying a full sequence of HERV-R under control of its own long terminal repeat (LTR) promoter. One line with tandem integration of multiple copies of the transgene expressed HERV-R mRNA in various organs with different expression levels and relatively hi...
|
PMID: 12779120
PDF is available here.
PDF is available here.
Shi yan sheng wu xue bao (36)2 2003
Abstract
The distribution of Bursin in major immune organs such as bursa of Fabricius (BF), thymus (Th), Harderian gland(HG) and spleen(Sp) was investigated and compared in both chicken and duck by immuno-histochemical staining method with anti-Bursin monoclonal antibody (McAb)2F9-4. Its distributions in bon...
|
PMID: 12858515
PDF is available here.
PDF is available here.
Abstract
In the present paper, binding of melatonin to purified cell nuclei from harderian glands of male and female hamsters was assessed. Binding of 125I-melatonin to cell nuclei fulfills the criteria for binding to a receptor site. Binding kinetics exhibit properties such as dependence on time and tempera...
|
PMID: 12614480
PDF is available here.
PDF is available here.
Abstract
We investigated the effects of diazepam (DZP) and its three metabolites: nordiazepam (NZP), oxazepam (OZP), and temazepam (TZP) on pineal gland nocturnal melatonin secretion. We looked at the effects of benzodiazepines on pineal gland melatonin secretion both in vitro (using organ perifusion) and in...
|
PMID: 12723886
PDF is available here.
PDF is available here.
Journal of Morphology (255)3 2003
Abstract
The orbital Harderian gland of the common tree shrew (Tupaia glis) was investigated at the macroscopic and microscopic levels. In the glands of both sexes only one acinar cell type was found. The cell is characterized by the presence of numerous lipid vacuoles of variable size and by a small number...
|
PMID: 12520550
PDF is available here.
PDF is available here.
Abstract
Immunohistochemical staining for lactoferrin was evident in the lacrimal gland and gland of the third eyelid in cattle and bison and the deep gland of the third eyelid (Harder's gland) in cattle. Equivocal staining for lactoferrin was seen for the Harder's gland in bison. An 80-kd band (lactoferrin)...
|
PMID: 12518886
PDF is available here.
PDF is available here.
Abstract
We have now studied the effects of continuous light (LL), which suppresses melatonin secretion by the pineal gland. Measurements were performed in two different circadian phases, in order to detect the presence or absence of day/night differences. In LL, no differences between circadian phases of su...
|
PMID: 12485373
PDF is available here.
PDF is available here.
Abstract
Harderian glands of the Wistar albino rats normal and adrenalectomized were investigated by light microscopy. In normal, these glands have a tubuloalveolar structure. The gland is located in the medio posterior aspect of the orbit. It is lobulated and appears homogeneous in colour and texture. Harde...
|
PMID: 14594194
PDF is available here.
PDF is available here.
Abstract
These results clearly demonstrate that the sand rat Harderian gland is affected by the diabetic syndrome induced by the synthetic diet....
|
PMID: 12470977
PDF is available here.
PDF is available here.
Journal of Anatomy (201)3 2002
Abstract
The intra-orbital lacrimal gland (Harderian gland, or HG) of the female rat was studied by magnetic resonance imaging (MRI) to evaluate whether MRI can be used to visualize the gland in vivo and localized-1H-spectroscopy detect its lipid content. The results were correlated with post-mortem anatomic...
|
PMID: 12363274
PDF is available here.
PDF is available here.