Abstract
The records of 33 dogs that had perianal fistula disease treated with en bloc surgical excision and bilateral anal saculectomy, and that were perioperatively administered an exclusive white fish and potato diet, were reviewed to determine outcome. By 1 year after surgery, 87.9% of the dogs had compl...
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PMID: 18981195
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Abstract
A four-year-old, entire male domestic cat was referred for assessment of a large abdominal mass of three-weeks duration. Diagnostic imaging suggested the presence of either splenic neoplasia, an abdominal abscess or haematoma. A coeliotomy was performed and an enlarged, irregular mass, including the...
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PMID: 17212749
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Abstract
A dose rate of 5 mg/kg every 24 hours was more effective at reducing the surface area and severity of PAF lesions than 2 mg/kg every 24 hours but less effective at resolving PAF lesions than previous studies using dose rates > or =5 mg/kg every 12 hours. CLINICAL RELEVANCE: Cyclosporine at 5 mg/kg e...
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PMID: 16911154
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Abstract
A 66-year-old Dutchman, living in Mali, presented with an extensive progressive perianal ulcer despite local and antibiotic treatment. Microscopic examination of the stool revealed Entamoeba histolytica/dispar cysts and phagocytosing trophozoites were seen in fresh scrapings of the ulcer, a diagnost...
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PMID: 15730040
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Abstract
These results suggest that increased expression of Mdm2 is an early event in circumanal gland tumorigenesis, and may be present in the absence of nuclear p53 protein accumulation....
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PMID: 15629477
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Abstract
We attempted to delineate intra- and interspecific differences among the anogenital gland secretions of two lemur species (Lemur catta and Propithecus verreauxi coquereli) using gas chromatography-mass spectrometry (GC-MS). The results indicate that the two species are discernible through scent. Fur...
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PMID: 15195327
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Abstract
The aim of this study was to detect immunohistochemically means growth hormone (GH) in 24 hepatoid gland adenomas and 5 hepatoid gland carcinomas and to compare the difference of immunoreactivity between types of tumors. The tumors were classified according to the WHO standards. Tissue sections whic...
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PMID: 15187372
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Abstract
The efficacy of the perineal stain as an index for sexual maturity and breeding condition in the male greater cane rat, Thryonomys swinderianus, Temminck, was investigated in 34 animals collected from hunters' kills in the Ekumfi District of Ghana, between April and June 1989. The results indicated...
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PMID: 14620588
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Abstract
The SAMP1/YitFc substrain exhibits unique characteristics when compared with the original Japanese strain. Of particular interest is the emergence of perianal fistulizing disease, to our knowledge the first report of such occurrence in an animal model of inflammatory bowel disease....
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PMID: 12671894
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Abstract
This article deals with the cytologic appearance of various glandular tissues located in the subcutaneous tissues. Normal cytologic features are described. In addition, inflammatory, infectious, neoplastic, and hyperplastic changes are discussed. Most of these features are depicted in the 60+ photom...
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PMID: 12469494
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Abstract
The skin of the perianal region is very thin and sensitive. The carbon dioxide laser is a very effective tool for removing tumors and treating conditions of this area. It offers a "no touch" method of treatment for conditions of the perianal region. There is less bleeding, less pain, less swelling w...
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PMID: 12064044
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Abstract
All dogs showed marked improvement in lesions and behaviour within 14 days of the medication. Fourteen dogs completed the trial. Two dogs were excluded due to concurrent disease. Thirteen dogs (93%) showed complete resolution of fistulas during the treatment period. Seven dogs (50%) had no recurrenc...
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PMID: 12054282
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Abstract
All dogs had resolution of clinical signs. Eight dogs went into remission; however, 5 of those 8 had recurrence of fistulas. Adverse effects of treatment were minimal and well tolerated. Cost of treatment was comparable to traditional surgical options and less than single agent cyclosporine treatmen...
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PMID: 12420778
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Abstract
We discuss strong and weak points of the data on dogs hepatoid circumanal glands published in 1950s-1990s in comparison with those obtained in our purposeful long-term investigation of various hepatoid glands. We strongly disagree with the viewpoint of Atoji et al. (1998); hepatoid circumanal glands...
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PMID: 12071053
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Abstract
We were successful in repeating the data of the discoverers of the hepatoid glands and proved that these glands are exocrine and that their cells excrete protein to intercellular channels and then to ducts and hair funnels. According to the published data, the odor of the secretory substance of the...
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PMID: 11963544
PDF is available here.
Abstract
In the 1920s-1930s, skin glands of a new type, hepatoid glands, were described in 13 mammal species (Rodentia, Canidae, and Bovidae). The hepatoid glands resemble sebaceous glands in their morphology, bur radically differ from them in specific structure of the acinus and another type of secretion. L...
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PMID: 12561331
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Abstract
In this study, the effect of doramectin, moxidectin and netobimin was investigated in naturally infected Syphacia muris in rats. The natural infection was determined by the use of cellophane tape method on the perianal region and by the technique of centrifugal flotation of feces. The infected rats...
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PMID: 10714468
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Abstract
The femoral or cloacal region of many species of lizards and amphisbaenians exhibits epidermal glands. The pores of these glands are plugged with holocrine solid secretions that serve as semiochemical sources. Many authors assume that these glands are mainly associated with reproduction and demarcat...
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PMID: 10461130
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Abstract
We examined the ultrastructure of the apocrine sweat glands in the circumanal glands of the dog in an effort to define more precisely the relationship between the apocrine sweat glands and the circumanal glands. Paraffin sections stained with azan and sections after immunohistochemical staining with...
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PMID: 9811218
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Abstract
Lobules of the circumanal glands have many characteristics of epidermis (a basal layer, a polyhedral or "spinous layer," a granular layer, and a horny layer) and they should not be classified as glandular tissue. The cysts in lobules can be interpreted as "closed hair canals." We suggest that steroi...
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PMID: 9517843
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Abstract
All cyclosporine-group dogs, but none of the control-group dogs, were subjectively improved after 4 weeks. Mean total surface area and mean fistula depth decreased 78 and 62%, respectively, in the cyclosporine-group dogs but increased 29 and 11%, respectively, in the control-group dogs. After 16 wee...
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PMID: 9373359
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Abstract
The purpose of this pilot study was to investigate the efficacy of cyclosporin in treating perianal fistulas (PAF) in dogs. Based on resolution of all fistulas in all dogs with remission times up to > 18 months, we conclude that cyclosporin therapy is the treatment of choice for PAF in dogs.
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PMID: 8993784
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Abstract
The cat supracaudal gland is usually considered as a conglomeration of massive sebaceous glands, although the author of the only detailed description of its structure stated that it is a hepatoid gland (HG) of lower order. Investigation of the supracaudal gland in adult cats of both sexes showed tha...
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PMID: 9410272
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Abstract
Twenty-seven German shepherd dogs with perianal fistulas and histological evidence of colitis were entered in a prospective clinical study to investigate the association between perianal fistula and colitis. Additionally, the response of perianal fistula disease to immunosuppressive doses of prednis...
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PMID: 8906729
PDF is available here.
Abstract
The histology of sexual dimorphism of the dog hepatoid circumanal glands has not been studied before. Studies of hepatoid and other skin glands of the circumanal region of adult dogs and puppies (1 and 38 days) of both sexes have shown striking differences in the structure of this region in adult ma...
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PMID: 8520438
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Abstract
Cysts are specific rounded closed structures characteristic of some hepatoid glands. They never occur in other cutaneous glands of mammals. The cysts of the circumanal hepatoid glands of the dog and polar fox, the violet gland of the polar and common red fox, and the groin pouches of three species o...
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PMID: 7894314
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Abstract
Studies on the circumanal skin of a three-week-old puppy have shown that, contrary to the adult dogs, sebaceous glands are absent here (although they are well-developed in other skin sites of the puppy). Hepatoid glands accompany every hair follicle; they differ considerably from hepatoid glands of...
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PMID: 8518722
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Abstract
Both the original material and the data from literature collected in two previous papers, show a considerable diversity of structure and secretion of the glands which constitute the hepatoid gland type. According to the body of available histological (including morphometrical) and histochemical data...
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PMID: 1304851
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Abstract
On either side of the cloaca of the male Monodelphis domestica, there is a large pack of globular structures lying between the external skin and the ischial arch. The structures within each of these bilateral complexes can be classified into three groups. Group 1 comprises different kinds of glands....
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PMID: 1883869
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Abstract
Three types of skin glands, the derivatives of the outer root sheath of the hair follicle, have been compared, which are represented by hepatoid, sebaceous and apocrine sweat glands. There are three characteristic properties inherent to hepatoid glands, existence of a network of intercellular secret...
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PMID: 1955615
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Abstract
Special features of Li+ transport in several organs ensuring ion homeostasis of vertebrates (in kidneys of fishes and mammals, in gills of teleost and rectal gland of elasmobranchs) are observed in comparison to Na+ transport in the same organs. Transport processes in extrarenal excretory organs--in...
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PMID: 1819169
PDF is available here.
Abstract
Although neoplastic changes in canine hepatoid perianal glands (HPG) are quite common, the biological behaviour is sometimes difficult to assess on the basis of the histopathological examination. In an attempt to detect differences in the glycoconjugate expression between normal and neoplastic HPG,...
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PMID: 2267415
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Abstract
alpha 2u-Globulin, the principal urinary protein of the male rat, has extensive sequence homology with many lipid binding proteins. The highest concentration of alpha 2u-globulin is found in the preputial gland, a holocrine secretory organ with pheromonal function. Meibomian and perianal glands are...
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PMID: 2463299
PDF is available here.
Abstract
Two cows with synchronised oestrous cycles were housed with a Friesian bull. During the midcycle period of the cows, one cow was given an intradermal injection of adrenaline in the perineal region. This caused local sweat gland discharge. The other cow was treated with water. The number and types of...
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PMID: 3413941
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Abstract
This paper describes a structural and histological study of the pre-anal glands of Hemidactylus flaviviridis. Only males possess these glands, which have a tubulo-acinar structure. They are holocrine in nature and become hyperactive during the breeding period. Thus they may be involved in the produc...
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PMID: 3693051
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Abstract
Epimastigotes were found multiplying in the anal glands and in hemocultures of an opossum; rare metacyclics were seen in the cultures. The flagellate is possibly T. (Megatrypanum) freitasi Rego, Magalhães & Siqueira, 1957, but its final identification is still pending.
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PMID: 3796278
PDF is available here.
Abstract
Gross and microanatomic features which may predispose the German Shepherd Dog to perianal fistulae formation were studied in 2 groups of clinically healthy dogs: a predisposed group (German Shepherd Dogs) and a control group comprising breeds not ordinarily affected by perianal fistulae. The dimensi...
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PMID: 4026029
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Abstract
During a 14-year period, carcinoma of the anal sac apocrine glands was found in 52 pastel and 8 sapphire mink (Mustela vison) kept for studies on slow viral diseases. The pastel mink varied in age from 72 to 135 months (mean age 108 months), the sapphire mink from 63 to 100 months (mean age 81 month...
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PMID: 4002534
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Abstract
Scanning electron micrographs showed that both epimastigotes and metacyclic trypomastigotes of Trypanosoma cruzi are attached by the flagellum to the epithelium of the rectal gland of Triatoma dimidiata. The flagellates tended to cover the surface of the gland and there was a marked predominance of...
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PMID: 6143481
PDF is available here.
Abstract
In the canine circumanal gland, the morphological alterations of peroxisomes during differentiation and maturation of the glandular cells were studied by electron microscopy, cytochemistry and freeze-etch technique. Each of the following three cell types has its own characteristic peroxisomal popula...
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PMID: 6721224
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Abstract
Transmission electron and light microscopy studies were carried out on morphologic characteristics of cellular organelles of normal and different neoplastic cells of hepatoid circumanal glands of 16 dogs. The ultrastructural features of the reserve and transitional cells in the adenomas and carcinom...
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PMID: 6838042
PDF is available here.
Abstract
The skins of mice, rats, rabbits, sheep, guinea pigs, and dogs were cultured for Propionibacterium acnes. Only the sebaceous regions (perianal gland) of guinea pigs harbored a significant P. acnes population. Analysis of the lipid from this region revealed a significant percentage of triglycerides,...
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PMID: 7259157
PDF is available here.
Abstract
Male C57BL/Icrf alpha t mice receiving long courses of weekly subcutaneous injections of 8.25 or 12.5 mg/kg, 1,2-dimethylhydrazine (DMH) developed perianal carcinomas as well as tumours at other sites. Tumours of the perianal gland or its associated hair root sheath and overlying skin included sebac...
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PMID: 7245248
PDF is available here.
Abstract
The cloaca of Myxine glutinosa was examined by histochemical and scanning electron microscopical methods. No copulation organ could be found in Myxine and no detectable differences in the anatomy of the cloaca between male and female Myxine glutinosa. The anal gland which is the only gland in the cl...
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PMID: 6461140
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Abstract
The present study applied the twin-ion technique of gas chromatography/mass spectrometry to establish 7 alpha-hydroxylation of 5 alpha-androstane-3 beta, 17 beta-diol by canine prostate, epididymis and perianal glands. 5 alpha-[4-14C, 7 beta-2H0.52]Androstane-3 beta, 17 beta-diol (0.5 microM) was in...
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PMID: 7408872
PDF is available here.