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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Photoreceptor Cells, Invertebrate (0):
Recent article
Photoreceptor Cells, Invertebrate
Abstract
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Abstract
We examine how these pathways contribute to visual motion detection by combining genetic block and reconstitution of neural activity in different lamina cell types with whole-cell recordings from downstream motion-sensitive neurons. We find reduced responses to moving gratings if L1 or L2 is blocked...
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PMID: 21068841
PDF is available here.
PDF is available here.
Abstract
Abstract
Abstract
We provide evidence that Drosophila Klp64D, a homolog of Kif3A motor subunit of the heterotrimeric Kinesin II complex, is essential for viability of developing photoreceptors and localization of junctional proteins. Genetic analysis of mutant clones shows that absence of Klp64D protein in early larv...
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PMID: 20506262
PDF is available here.
PDF is available here.
Optics Express (18)18 2010
Abstract
A 3D structured light sheet microscope using a four-faceted symmetric pyramid is presented. The sample is illuminated by the resulting four beam interference field. This approach combines advantages of standing wave and structured illumination microscopy. Examples of micrographs of fluorescently lab...
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PMID: 20940819
PDF is available here.
PDF is available here.
Abstract
We conclude that larvae of P. hilaris show a photoperiodic response after removal of stemmata, in contrast to larvae of L. kumagaii....
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PMID: 20230824
PDF is available here.
PDF is available here.
Abstract
Extending axons must choose the appropriate synaptic target cells in order to assemble functional neural circuitry. The axons of the Drosophila color-sensitive photoreceptors R7 and R8 project as a single fascicle from each ommatidium, but their terminals are segregated into distinct layers within t...
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PMID: 20434326
PDF is available here.
PDF is available here.
Journal of Experimental Biology (213)Pt 14 2010
Abstract
We aimed to determine characteristics of stimuli that elicit orienting responses mediated by the AL eyes. After covering all eyes except the AL eyes, we measured orienting responses to dot stimuli that varied in size and contrast, and moved at different speeds. We found that all stimulus parameters...
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PMID: 20581266
PDF is available here.
PDF is available here.
Abstract
We compare with other species. This article outlines four grades of 'colour vision' that can be related to the behavioural uses of spectral information, and perhaps to the underlying mechanisms. In the first, even without an (image-forming) eye, simple organisms can compare photoreceptor signals to...
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PMID: 20164101
PDF is available here.
PDF is available here.
Abstract
We show that a disruption of the JmjC domain of dUTX results in a growth advantage for mutant cells over adjacent wild-type tissue due to increased proliferation. The growth advantage of dUTX mutant tissue is caused, at least in part, by increased Notch activity, demonstrating that dUTX is a Notch a...
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PMID: 20212086
PDF is available here.
PDF is available here.
Abstract
We show that chinmo is a cell-autonomous, downstream mediator of Stat92E that shares numerous functions with this protein. Loss of either gene results in malformed eyes and head capsules due to defects in eye progenitor cells. Hyperactivation of Stat92E or misexpression of Chinmo results in blood ce...
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PMID: 20412771
PDF is available here.
PDF is available here.
Journal of Neuroscience (30)15 2010
Abstract
We describe mutations in the Drosophila gene importin-beta11, which has not previously been analyzed genetically. Mutants of importin-beta11 died as late pupae from neuronal defects, and neuronal importin-beta11 was present not only at nuclear pores but also in the cytosol and at synapses. Neurons l...
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PMID: 20392948
PDF is available here.
PDF is available here.
Current Biology (20)7 2010
Abstract
Taking these results together, we demonstrate that the DN1(p)s lie at the nexus of PDF and photic signaling to produce appropriate daily behavior....
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PMID: 20362452
PDF is available here.
PDF is available here.
Current Biology (20)7 2010
Abstract
How does the Drosophila circadian control network respond to seasonal environmental changes? Genetic manipulations that target a small subset of clock neurons reveal that they integrate seasonal cues of light and temperature to modulate the daily distribution of rest and activity.
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PMID: 20392424
PDF is available here.
PDF is available here.
Journal of Neuroscience (30)4 2010
Abstract
We used proteomic, genetic, and electrophysiological approaches to characterize Retinophilin (RTP) (CG10233) in Drosophila photoreceptors and establish its involvement in dark-noise suppression. RTP possesses membrane occupation and recognition nexus (MORN) motifs, a structure shared with mammalian...
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PMID: 20107052
PDF is available here.
PDF is available here.
PLoS Biology (8)12 2010
Abstract
We show that loss of the neuron-specific v-ATPase subunit a1 leads to progressive endosomal guidance receptor accumulations after neuronal differentiation. In the embryo and in adult photoreceptors, these accumulations occur after axon pathfinding and synapse formation is complete. In contrast, rece...
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PMID: 21151882
PDF is available here.
PDF is available here.
PLoS Biology (8)12 2010
Abstract
We show that loss of the neuron-specific v-ATPase subunit a1 leads to progressive endosomal guidance receptor accumulations after neuronal differentiation. In the embryo and in adult photoreceptors, these accumulations occur after axon pathfinding and synapse formation is complete. In contrast, rece...
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PMID: 21151882
PDF is available here.
PDF is available here.
Abstract
I review our current understanding of PCP signaling in the Drosophila eye and allude to parallels in vertebrates.
Copyright © 2010 Elsevier Inc. All rights reserved....
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PMID: 20959167
PDF is available here.
PDF is available here.
Abstract
Cells are sequentially recruited during formation of the Drosophila compound eye. A few simple rules are reiteratively utilized to control successive steps of eye assembly. Two themes emerge: the interplay between cell signaling and competence determines diversity of cell types and selective cell ad...
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PMID: 20959164
PDF is available here.
PDF is available here.
Abstract
We discuss emerging evidence that the different functional components of the fly eye share developmental pathways and functions with the vertebrate eye.
Copyright © 2010 Elsevier Inc. All rights reserved....
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PMID: 20959165
PDF is available here.
PDF is available here.
Abstract
The road to producing an eye begins with the decision to commit a population of cells to adopting an eye tissue fate, the process of retinal determination. Over the past decade and a half, a network of transcription factors has been found to mediate this process in all seeing animals. This retinal d...
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PMID: 20959161
PDF is available here.
PDF is available here.
Abstract
Circadian rhythms are known for locomotory and reproductive behaviours, and the functioning of sensory organs, nervous structures, metabolism and developmental processes. The mechanisms and cellular bases of control are mainly inferred from circadian phenomenologies, ablation experiments and pharmac...
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PMID: 20515741
PDF is available here.
PDF is available here.
Abstract
We cloned four cDNAs encoding visual pigment opsins, corresponding to one ultraviolet, two blue and one long wavelength-absorbing visual pigments. Duplication of the blue visual pigment class occurs also in another pierid species, Pieris rapae, suggesting that blue duplication is a general feature i...
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PMID: 19224222
PDF is available here.
PDF is available here.
EMBO Journal (28)4 2009
Abstract
One of the striking findings in developmental genetics over the past two decades is the realization that a very small number of conserved signalling pathways directs most, if not all, aspects of development of multicellular organisms, by transmitting extracellular signals to the cell nucleus, to mod...
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PMID: 19225444
PDF is available here.
PDF is available here.
Abstract
The sine oculis homeobox (SIX) protein family is a group of evolutionarily conserved transcription factors that are found in diverse organisms that range from flatworms to humans. These factors are expressed within, and play pivotal developmental roles in, cell populations that give rise to the head...
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PMID: 18989625
PDF is available here.
PDF is available here.
Abstract
Differentiation of the Drosophila compound eye from the eye imaginal disc is a progressive process: columns of cells successively differentiate in a posterior to anterior sequence, clusters of cells form at regularly spaced intervals within each column, and individual photoreceptors differentiate in...
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PMID: 19557685
PDF is available here.
PDF is available here.
Abstract
Basic variants of the evolutional program for formation of simple sensor system--structural models of gravitation receptor, organ of vision, chemoreceptor organ as well as of the nervous system at early stages of the metazoan phylogenesis--are considered from results of our own morphofunctional stud...
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PMID: 19435256
PDF is available here.
PDF is available here.
Abstract
We present the first ontogenetic examination of the eyes of philomedid ostracods (Crustacea), which exhibit extremely sexually dimorphic lateral eyes. Adult male philomedids have large compound lateral eyes, whereas females have rudimentary lateral eyes. First, we show that eye dimorphism is unlikel...
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PMID: 19245554
PDF is available here.
PDF is available here.
Abstract
We measured the in vivo absorption spectra of the two stable states A and B of photoreceptor photocycle. Data were collected using two different devices, i.e. a microspectrophotometer and a digital microscope. Our results show that the photocycle and the absorption spectra of the photoreceptor posse...
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PMID: 18764888
PDF is available here.
PDF is available here.
Abstract
An action spectrum was obtained for the suppression of arylalkylamine N-acetyltransferase (NAT) activity in the two-spotted spider mite Tetranychus urticae by irradiating the mite with monochromatic lights of various wavelengths using the Okazaki Large Spectrograph at the National Institute for Basi...
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PMID: 18764905
PDF is available here.
PDF is available here.
Visual Neuroscience (26)4 2009
Abstract
The visual abilities of sharks show substantial interspecific variability. In addition, sharks may change their habitat and feeding strategy throughout life. As the eyes of sharks continue to grow throughout the animal's lifetime, ontogenetic variability in visual ability may also occur. The topogra...
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PMID: 19698193
PDF is available here.
PDF is available here.
Abstract
We developed genetic techniques that link behavior to single cell-type resolution within the Drosophila central brain. We focused on the unknown function of the 10 PDF-containing large ventral lateral neurons (l-LNvs) of the Drosophila circadian brain network and show here that these cells function...
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PMID: 19060186
PDF is available here.
PDF is available here.
Abstract
We show that the temporal expression dynamics of the zinc-finger protein sequoia is the major determinant of Drosophila photoreceptor connectivity into distinct synaptic layers. Neighbouring R8 and R7 photoreceptors show consecutive peaks of elevated sequoia expression, which correspond to their seq...
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PMID: 18978776
PDF is available here.
PDF is available here.
Abstract
We show that a key step in the targeting of the R7 neuron is the active repression of the R8 targeting program. Repression is dependent on NF-YC, a subunit of the NF-Y (nuclear factor Y) transcription factor. In the absence of NF-YC, R7 axons terminate in the same layer as R8 axons. Genetic experime...
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PMID: 18978774
PDF is available here.
PDF is available here.
Journal of Neuroscience (28)50 2008
Abstract
We report a gene named tadr (for torn and diminished rhabdomeres), which, when mutated, leads to photoreceptor degeneration through a different mechanism. Degeneration in the tadr mutant is characterized by shrunk and disrupted rhabdomeres, the light sensory organelles of photoreceptor. The TADR pro...
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PMID: 19074021
PDF is available here.
PDF is available here.
Abstract
We here cloned and functionally characterized the ninaB gene from the great wax moth Galleria mellonella. We show that the recombinant purified enzyme combines isomerase and oxygenase (isomerooxygenase) activity in a single polypeptide. From kinetics and isomeric composition of cleavage products of...
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PMID: 19020100
PDF is available here.
PDF is available here.
Abstract
The Dscam family of immunoglobulin cell surface proteins mediates recognition events between neurons that play an essential role in the establishment of neural circuits. The Drosophila Dscam1 locus encodes tens of thousands of cell surface proteins via alternative splicing. These isoforms exhibit ex...
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PMID: 18837673
PDF is available here.
PDF is available here.
Abstract
This paper deals with the first characterization of the structure of the photoreceptive organelle of the unicellular alga Euglena gracilis (Euglenophyta). This organelle has a three-dimensional organization consisting of up to 50 closely stacked membrane lamellae. Ionically induced unstacking of the...
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PMID: 18722349
PDF is available here.
PDF is available here.
Abstract
We identified the first-order interneurons downstream of the chromatic channels. Serial EM revealed that small-field projection neurons Tm5 and Tm9 receive direct synaptic input from R7 and R8, respectively, and indirect input from R1-R6, qualifying them to function as color-opponent neurons. Wide-f...
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PMID: 18957224
PDF is available here.
PDF is available here.
Journal of Biological Chemistry (283)39 2008
Abstract
We identified Munc119 as a RIBEYE-interacting protein at photoreceptor ribbon synapses using five independent approaches. The PrBP/delta homology domain of Munc119 is essential for the interaction with the NADH binding region of RIBEYE(B) domain. But RIBEYE-Munc119 interaction does not depend on NAD...
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PMID: 18664567
PDF is available here.
PDF is available here.
Journal of Biological Chemistry (283)38 2008
Abstract
We assessed the therapeutic effects of heat shock transcription factor 1 (HSF1)-activating compounds, which induce multiple molecular chaperones, on polyQ-induced neurodegeneration in vivo. We found that oral administration of 17-(allylamino)-17-demethoxygeldanamycin (17-AAG) markedly suppresses com...
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PMID: 18632670
PDF is available here.
PDF is available here.
Current Biology (18)17 2008
Abstract
Our findings support a monophyletic origin for the bilaterian visual system in which the last common ancestor of flies and vertebrates already contained a primordial visual system with photoreceptors, interneurons, and projection neurons....
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PMID: 18723351
PDF is available here.
PDF is available here.
Abstract
We investigate the mechanism and role of rhodopsin inactivation. We determined the lifetime of activated rhodopsin (metarhodopsin = M( *)) in whole-cell recordings from Drosophila photoreceptors by measuring the time window within which inactivating M( *) by photoreisomerization to rhodopsin could s...
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PMID: 18786361
PDF is available here.
PDF is available here.
Abstract
We investigate the role of the crayfish caudal photoreceptor (CPR) as a candidate to form part of this pacemaking circadian system. Two circadian rhythms are documented for CPR electrical activity. These rhythms correspond to the spontaneous and light-induced discharge of action potentials. The intr...
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PMID: 18563837
PDF is available here.
PDF is available here.
Abstract
External and internal head structures of Caurinus dectes were examined and described in detail. The features are compared to conditions found in other groups of Antliophora. Caurinus is obviously crucial for the reconstruction of the mecopteran and antliophoran groundplan. It displays a remarkable s...
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PMID: 18555961
PDF is available here.
PDF is available here.
Abstract
We show that light selectively modulated the delayed rectifier (Shab) current. Shab currents were increased by light with similar kinetics to the light-induced current itself (latency approximately 20 ms), recovering to control values with a t(1/2) of approximately 60 s in darkness. Genetic disrupti...
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PMID: 18760696
PDF is available here.
PDF is available here.
Brain Research (1225) 2008
Abstract
Simple photoreceptors, namely photoresponsive neurons without microvilli and/or cilia have long been known in the central ganglion of crayfish, Aplysia, Onchidium and Helix. Recently, similar simple photoreceptors, ipRGCs were discovered in the mammalian retinas. A characteristic common to all of th...
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PMID: 18538313
PDF is available here.
PDF is available here.
Abstract
These results demonstrate that intron 1 is sufficient for high-amplitude cry mRNA cycling, show that cry upstream sequences are sufficient for expression in brain oscillator neurons, and suggest that cry spatial and circadian expression are regulated by different elements....
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PMID: 18663236
PDF is available here.
PDF is available here.
Abstract
We expected this protein to be expressed in all oscillator cells, yet CRY cellular distribution and subcellular localization has not been firmly established. Here we investigate CRY spatial expression in the brain using a newly developed CRY antibody and a novel set of cry deletion mutants. We find...
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PMID: 18663237
PDF is available here.
PDF is available here.
Abstract
We present a quantitative model explaining how QBs emerge from stochastic nonlinear dynamics of the signaling cascade. The model shows that the cascade acts as an "integrate and fire" device and explains how photoreceptors achieve reliable responses to light although keeping low background in the da...
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PMID: 18653755
PDF is available here.
PDF is available here.
Development (135)16 2008
Abstract
We show that the transcription of pros is activated by two visual-specific transcription selectors, Glass and Sine Oculis, that bind to an enhancer and promote its activation. Together with the pre-patterning transcription factor Lozenge, these factors work in a highly combinatorial manner, such tha...
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PMID: 18635611
PDF is available here.
PDF is available here.
Abstract
We show that, during metamorphosis, all Rh6 photoreceptors die, whereas the Rh5 photoreceptors switch fate by turning off Rh5 and then turning on Rh6 expression. This switch occurs without apparent changes in the programme of transcription factors that specify larval photoreceptor subtypes. We also...
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PMID: 18594514
PDF is available here.
PDF is available here.
Journal of Neuroscience (28)29 2008
Abstract
Our results suggest that the native receptor at the LMC synapse is an HCLA homomer, whereas HCLB signaling via the lamina glia plays a previously unrecognized role in shaping the LMC postsynaptic response....
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PMID: 18632929
PDF is available here.
PDF is available here.
Current Biology (18)13 2008
Abstract
We show that Ca(2+)-activated Myosin V (MyoV) pulls pigment granules to the rhabdomere. Thus, one of MyoV's several functions is also as a sensory-adaptation motor. In vitro, Ca(2+) both activates and inhibits MyoV motility; in vivo, its role is undetermined. This first demonstration of an in vivo r...
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PMID: 18585038
PDF is available here.
PDF is available here.
Journal of Experimental Biology (211)Pt 14 2008
Abstract
We have analyzed the masking effects of a lights-on (LOn) signal on Drosophila eclosion. The LOn response results in 12-21% of the flies that emerge on a given day eclosing within 10 min of the LOn signal. Flies that lack the neuropeptide eclosion hormone (EH), or in which its release is inhibited b...
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PMID: 18587121
PDF is available here.
PDF is available here.
Abstract
We demonstrate that ectopic eyes on antennae and legs extend axonal projections to the central nervous system. Furthermore, electroretinograms and morphological evidence indicate that the photoreceptor axons of at least the antennal ectopic eyes can form completely constituted ectopic synapses with...
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PMID: 18577588
PDF is available here.
PDF is available here.
Abstract
We show that camera-type eyes of the cubozoan jellyfish, Tripedalia cystophora, use genetic building blocks typical of vertebrate eyes, namely, a ciliary phototransduction cascade and melanogenic pathway. Our findings indicative of parallelism provide an insight into eye evolution. Combined, the ava...
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PMID: 18577593
PDF is available here.
PDF is available here.
Cell and Tissue Research (333)1 2008
Abstract
We have used immunohistochemistry with a range of vertebrate opsin antibodies to label the photoreceptors, and electroretinograms (ERG) to determine their spectral sensitivity. All photoreceptor cells of the two lens eyes of the box jellyfish Tripedalia cystophora and Carybdea marsupialis displayed...
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PMID: 18504619
PDF is available here.
PDF is available here.