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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Vibrissae (0):
Recent article
Vibrissae
Abstract
We report that early gamma oscillations (EGOs) enable precise spatiotemporal thalamocortical synchronization in the neonatal rat whisker sensory system. Driven by a thalamic gamma oscillator and initially independent of cortical inhibition, EGOs synchronize neurons in a single thalamic barreloid and...
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PMID: 21998388
PDF is available here.
PDF is available here.
| < More recent | Older article > |
Abstract
We recorded single-unit firing and local field potentials from the CA1 region of hippocampus while rats performed a task in which tactile stimuli specified reward location. On each trial the rat touched a textured plate with its whiskers, and then turned towards the Left or Right water spout. Two te...
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PMID: 21305039
PDF is available here.
PDF is available here.
Nature Neuroscience (13)12 2010
Abstract
We found that performance in detecting vibrissal deflections degraded with adaptation while performance in discriminating among vibrissal deflections of different velocities was enhanced, a trend not observed in thalamus. Analysis of simultaneously recorded thalamic neurons did reveal, however, an a...
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PMID: 21102447
PDF is available here.
PDF is available here.
Neuroscience (170)2 2010
Abstract
We found that enrichment increased all SEP response components subsequent to the initial thalamocortical input, but only when evoked by single stimuli; the thalamocortical component remained unchanged across all animal groups. The optical signal exhibited no changes in amplitude or latency between g...
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PMID: 20654700
PDF is available here.
PDF is available here.
Brain research (1354) 2010
Abstract
The primary goal of this study was to examine in the rat whether neurons in the tuberomammillary nucleus (TMN) provide axon collaterals to whisker-related, sensorimotor regions at cortical and brainstem levels, using two different retrograde tracers. When injections were made at primary sensory (S1)...
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PMID: 20682294
PDF is available here.
PDF is available here.
Abstract
We compared the behavioral effects of chronic parenteral administration of a water extract of M. pruriens seed powder (MPE) alone without any additives, MPE combined with the peripheral dopa-decarboxylase inhibitor (DDCI) benserazide (MPE+BZ), LD+BZ and LD alone without BZ in the hemiparkinsonian ra...
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PMID: 20570206
PDF is available here.
PDF is available here.
Behavioural Brain Research (211)2 2010
Abstract
In order to explore the role of active whisking in object novelty detection, the performance of rats having bilateral vibrissal paralysis was compared to that of non-lesioned animals in three modified versions of the one-trial object recognition task performed in the dark. Vibrissal paralysis was in...
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PMID: 20347880
PDF is available here.
PDF is available here.
Journal of Neuroscience (30)26 2010
Abstract
We explore how facial-motoneuron spikes are translated, via an intrinsic muscle, to whisker movements. This is achieved by constructing, simulating, and analyzing a computational, biomechanical model of the motor plant, and by measuring spiking to movement transformations at small and large angles u...
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PMID: 20592215
PDF is available here.
PDF is available here.
Journal of Neuroscience (30)25 2010
Abstract
We recorded unit and field potential activity in the intermediate layers of the superior colliculus of rats during active avoidance behavior. During the period preceding the onset of the WCS, avoids are associated with a higher firing rate than escapes (unsuccessful avoids), indicating that a prepar...
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PMID: 20573897
PDF is available here.
PDF is available here.
Brain research (1336) 2010
Abstract
The primary goal of this anatomical study was to examine in the rat whether cholinergic neurons provide axon collaterals to whisker-related, sensorimotor regions at cortical, thalamic, and brainstem levels, using a combined method of retrograde tracing and choline acetyltransferase (ChAT) immunostai...
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PMID: 20381464
PDF is available here.
PDF is available here.
NeuroImage (51)2 2010
Abstract
We report a novel method to detect individual whisker barrels by using discriminant analysis to jointly characterize high order dependency among multiple voxels. Our results in the whisker barrel cortex of the awake rabbit indicate that the proposed method can differentiate reliably small clusters o...
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PMID: 20171289
PDF is available here.
PDF is available here.
Abstract
We summarize progress on detection of surface texture (roughness). Texture appears to be inferred from the statistics of complex, irregular whisker micromotion on surfaces, specifically by mean speed or by patterns of discrete, high-velocity whisker slips. These are encoded in S1 by mean firing rate...
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PMID: 20299205
PDF is available here.
PDF is available here.
Abstract
We tested the hypothesis that overexpression of fetuin-A in Abcc6(-/-) mice counteracts the ectopic mineralization. Delivery of an expression construct containing full-length mouse fetuin-A complementary DNA (cDNA), linked to a His-tag, to the liver of these mice resulted in elevated serum levels of...
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PMID: 20090764
PDF is available here.
PDF is available here.
Hypertension (55)4 2010
Abstract
We investigated the role of EP1R in the cerebrovascular alterations induced by Ang II. Mice were equipped with a cranial window, and cerebral blood flow was monitored by laser-Doppler flowmetry. The attenuation in cerebral blood flow responses to whisker stimulation (-46+/-4%) and the endothelium-de...
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PMID: 20194308
PDF is available here.
PDF is available here.
Hypertension (55)4 2010
Abstract
We investigated the role of EP1R in the cerebrovascular alterations induced by Ang II. Mice were equipped with a cranial window, and cerebral blood flow was monitored by laser-Doppler flowmetry. The attenuation in cerebral blood flow responses to whisker stimulation (-46+/-4%) and the endothelium-de...
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PMID: 20194308
PDF is available here.
PDF is available here.
Hypertension (55)4 2010
Abstract
We investigated the role of EP1R in the cerebrovascular alterations induced by Ang II. Mice were equipped with a cranial window, and cerebral blood flow was monitored by laser-Doppler flowmetry. The attenuation in cerebral blood flow responses to whisker stimulation (-46+/-4%) and the endothelium-de...
|
PMID: 20194308
PDF is available here.
PDF is available here.
Hypertension (55)4 2010
Abstract
We investigated the role of EP1R in the cerebrovascular alterations induced by Ang II. Mice were equipped with a cranial window, and cerebral blood flow was monitored by laser-Doppler flowmetry. The attenuation in cerebral blood flow responses to whisker stimulation (-46+/-4%) and the endothelium-de...
|
PMID: 20194308
PDF is available here.
PDF is available here.
Hypertension (55)4 2010
Abstract
We investigated the role of EP1R in the cerebrovascular alterations induced by Ang II. Mice were equipped with a cranial window, and cerebral blood flow was monitored by laser-Doppler flowmetry. The attenuation in cerebral blood flow responses to whisker stimulation (-46+/-4%) and the endothelium-de...
|
PMID: 20194308
PDF is available here.
PDF is available here.
Hypertension (55)4 2010
Abstract
We investigated the role of EP1R in the cerebrovascular alterations induced by Ang II. Mice were equipped with a cranial window, and cerebral blood flow was monitored by laser-Doppler flowmetry. The attenuation in cerebral blood flow responses to whisker stimulation (-46+/-4%) and the endothelium-de...
|
PMID: 20194308
PDF is available here.
PDF is available here.
Hypertension (55)4 2010
Abstract
We investigated the role of EP1R in the cerebrovascular alterations induced by Ang II. Mice were equipped with a cranial window, and cerebral blood flow was monitored by laser-Doppler flowmetry. The attenuation in cerebral blood flow responses to whisker stimulation (-46+/-4%) and the endothelium-de...
|
PMID: 20194308
PDF is available here.
PDF is available here.
Hypertension (55)4 2010
Abstract
We investigated the role of EP1R in the cerebrovascular alterations induced by Ang II. Mice were equipped with a cranial window, and cerebral blood flow was monitored by laser-Doppler flowmetry. The attenuation in cerebral blood flow responses to whisker stimulation (-46+/-4%) and the endothelium-de...
|
PMID: 20194308
PDF is available here.
PDF is available here.
Hypertension (55)4 2010
Abstract
We investigated the role of EP1R in the cerebrovascular alterations induced by Ang II. Mice were equipped with a cranial window, and cerebral blood flow was monitored by laser-Doppler flowmetry. The attenuation in cerebral blood flow responses to whisker stimulation (-46+/-4%) and the endothelium-de...
|
PMID: 20194308
PDF is available here.
PDF is available here.
Hypertension (55)4 2010
Abstract
We investigated the role of EP1R in the cerebrovascular alterations induced by Ang II. Mice were equipped with a cranial window, and cerebral blood flow was monitored by laser-Doppler flowmetry. The attenuation in cerebral blood flow responses to whisker stimulation (-46+/-4%) and the endothelium-de...
|
PMID: 20194308
PDF is available here.
PDF is available here.
Hypertension (55)4 2010
Abstract
We investigated the role of EP1R in the cerebrovascular alterations induced by Ang II. Mice were equipped with a cranial window, and cerebral blood flow was monitored by laser-Doppler flowmetry. The attenuation in cerebral blood flow responses to whisker stimulation (-46+/-4%) and the endothelium-de...
|
PMID: 20194308
PDF is available here.
PDF is available here.
Journal of Neurotrauma (27)4 2010
Abstract
Post-traumatic morbidity reduces the quality of life for traumatic brain injury (TBI) survivors by altering neuropsychological function. After midline fluid percussion injury (FPI), diffuse pathology in the ventral posterior thalamus suggests that somatosensory whisker function may be impaired post-...
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PMID: 20067394
PDF is available here.
PDF is available here.
Journal of Neuroscience (30)14 2010
Abstract
We show that in wild-type mice, whisker potentiation and spine stabilization are most pronounced for layer 5 neurons at the border between spared and deprived barrel columns. In homozygote alphaCaMKII-T286A mice, which lack experience-dependent potentiation of responses to spared whiskers, there is...
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PMID: 20371813
PDF is available here.
PDF is available here.
Abstract
The facial palsy of the group two rats was more severe than that of group one rats, although their facial nerve function had partly recovered on the 21st post-operative day. Fibre degeneration was not only dispersed throughout the injury site but also occurred throughout the length of the nerve. Neu...
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PMID: 19930777
PDF is available here.
PDF is available here.
Neuropharmacology (58)3 2010
Abstract
We evaluated the efficacy of the new adenosine A(2A) receptor antagonist 8-ethoxy-9-ethyladenine (ANR 94) in parkinsonian models of akinesia and tremor. In addition, induction of the immediate early gene zif-268, and neuroprotective and anti-inflammatory effects of ANR 94 were evaluated. ANR 94 was...
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PMID: 19951715
PDF is available here.
PDF is available here.
Journal of Neuroscience (30)3 2010
Abstract
We show using quantitative transmission electron microscopy that a simple form of learning involving mystacial vibrissae results in approximately 70% increase in the density of inhibitory synapses on spines of neurons located in layer IV barrels that represent the stimulated vibrissae. The spines co...
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PMID: 20089926
PDF is available here.
PDF is available here.
Abstract
These results suggest that norgalanthamine, a principal of C. asiaticum, has the potential to promote hair growth via the proliferation of dermal papilla....
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PMID: 19822478
PDF is available here.
PDF is available here.
Abstract
We have previously shown that susceptibility to HSE was host-strain dependent, as severe, lethal HSE developed after injection of human Herpes simplex type 1 virus (HSV-1) into the whiskers area of DA rats, whereas PVG rats remained completely asymptomatic. In the present study we investigated the e...
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PMID: 20806060
PDF is available here.
PDF is available here.
Abstract
Mechanical allodynia was established within 3 days and lasted beyond postoperative day 24. Intraperitoneal administration of morphine (2 or 5 mg/kg) significantly blocked mechanical allodynia ipsilateral to the compression of the trigeminal ganglion. Intraperitoneal administration of morphine also i...
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PMID: 20213037
PDF is available here.
PDF is available here.
Abstract
The intracisternal administration of 25, 50, or 100 Microg of memantine, an antagonist that acts at the NMDA ion channel site, significantly suppressed the number of scratches in the second phase of the behavioral responses to formalin. Intracisternal administration of a range of doses of 5,7-dichlo...
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PMID: 20401359
PDF is available here.
PDF is available here.
Abstract
We aimed to determine the somatotopy and morphological features of the thalamocortical neurons within mouse VL. Retrograde tracing studies revealed that whisker-related VL neurons were found relatively anterior and medial to those labeled following injection of retrograde tracer into hindpaw motor a...
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PMID: 20141408
PDF is available here.
PDF is available here.
Brain Research (1283) 2009
Abstract
We investigated in the rat whether hypoglossal innervation extended to facial muscles other than the extrinsic musculature of the mystacial pad. Results showed that hypoglossal neurons also innervate the masseter muscle. Dil injected into the XII nucleus showed hypoglossal axons in the ipsilateral m...
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PMID: 19523459
PDF is available here.
PDF is available here.
Journal of Neurophysiology (102)1 2009
Abstract
We used disinhibition produced by GABA receptor antagonists to unmask the excitatory sensory responses that are normally suppressed by inhibition in the main subcortical sensory relays to barrel cortex; principal trigeminal (Pr5) and primary thalamic (VPM) nuclei. We found that, within subcortical r...
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PMID: 19403743
PDF is available here.
PDF is available here.
Biological Cybernetics (100)6 2009
Abstract
We consider are: the role of spike timing; mechanisms of spike timing; decoding and context-dependence. Significant insight has come from the development of rigorous, information theoretic frameworks for tackling these questions, in conjunction with suitably designed experiments. We review both the...
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PMID: 19189120
PDF is available here.
PDF is available here.
Abstract
The twenty-first annual Barrels meeting, sponsored by NINDS, was held on 12–14 November 2008 on the campus of Johns Hopkins University, near the site of the original discovery of barrels almost 40 years ago. The longest running satellite meeting to the Society for Neuroscience Annual Meeting focuse...
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PMID: 19283554
PDF is available here.
PDF is available here.
Abstract
DHA pretreatment improved forepaw placing response to near-normal levels (9.5 +/- 0.9 treatment vs 7.1 +/- 2.2 controls; normal = 10; P < .0001). DHA attenuated hemisphere damage compared with controls (P = .0155), with particular benefit in the hippocampus with 1 mg/kg (38% protection vs albumin co...
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PMID: 19254588
PDF is available here.
PDF is available here.
Abstract
We hypothesized that 17beta-estradiol combined with an EE would accelerate cognitive recovery after focal brain ischemia in ovariectomized rats and that recovery would be related to altered expression of nerve growth factor-induced gene (NGFI)-A in the hippocampus. 17beta-estradiol or placebo pellet...
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PMID: 19302156
PDF is available here.
PDF is available here.
Abstract
We examined a murine PXE model (Abcc6(-/-)) by transplanting muzzle skin from knockout (KO) and wild-type (WT) mice onto the back of WT and KO mice using mineralization of the connective tissue capsule surrounding the vibrissae as an early phenotypic biomarker. Grafting of WT mouse muzzle skin onto...
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PMID: 18685618
PDF is available here.
PDF is available here.
Behavioural Brain Research (197)1 2009
Abstract
We quantified their behaviors during training with an ethogram and measured each individual animals' progress over the training period. Once calm under restraint, rats were conditioned to differentiate between a reward and control whisker twitch, then provide a lick response when presented with the...
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PMID: 18718491
PDF is available here.
PDF is available here.
Journal of Neuroscience (29)4 2009
Abstract
We use juxtasomal recording and stimulation techniques to probe subthreshold response properties of antidromically identified CT neurons in the rat whisker/barrel system. When neuronal firing is facilitated by depolarizing juxtasomal currents, silent neurons become responsive to whisker stimuli, per...
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PMID: 19176805
PDF is available here.
PDF is available here.
Abstract
Our data reveal that neurons in layers IV and Vb comprise a population of rapidly adapting neurons and neurons in layer Va are slowly adapting. Our findings suggest that the somatosensory cortex receive lemniscal and paralemniscal projections. A cooperation of lemniscal and paralemniscal projection...
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PMID: 19338254
PDF is available here.
PDF is available here.
Abstract
We believe that precisely controlling the timing and parameters of stimulation in closed loop can significantly improve the efficacy of this technique. Here, we present a system for closed-loop microstimulation in awake rodents chronically implanted with multielectrode arrays. The system interfaces...
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PMID: 19224714
PDF is available here.
PDF is available here.
Abstract
We suggest using the term 'vibrissal sense' for the vibrissa system of aquatic mammals.
2009 S. Karger AG, Basel....
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PMID: 19996585
PDF is available here.
PDF is available here.
Abstract
We delivered tactile stimuli to the rat vibrissae using a new 24 whisker stimulator. We tested sequences of rostrocaudal whisker deflections that generate multivibrissal motion patterns in different directions across the mystacial pad, allowing to disambiguate local from global sensory integration....
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PMID: 19109915
PDF is available here.
PDF is available here.
Journal of Neuroscience (28)51 2008
Abstract
We show that the magnitude of the experience-dependent regulation of vesicular zinc is significantly increased through enriched-environment housing. Mice were reared either in a deprived environment and subsequently housed in deprived, minimally enriched, or enriched conditions after the removal of...
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PMID: 19091988
PDF is available here.
PDF is available here.
Abstract
We aimed to determine the nature of the tactile information encoded by neurons in the whisker somatosensory relay nucleus (VPm). We wanted to distinguish whether VPm neurons encode similar stimulus features, acting as a single information channel, or encode diverse features. We recorded responses to...
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PMID: 19081382
PDF is available here.
PDF is available here.
Abstract
We find that whisker deprivation increases LTP in the layer IV to II/III pathway and that PKA antagonists block the additional LTP. No LTP was seen in undeprived CaMKII-T286A mice, but whisker deprivation again unmasked PKA-sensitive LTP. Infusion of a PKA agonist potentiated EPSPs in deprived wild-...
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PMID: 19081380
PDF is available here.
PDF is available here.
Abstract
Journal of Neuroscience (28)50 2008
Abstract
This study investigated the role of sensory experience in the refinement of whisker sensory relay synapses in the ventral posterior medial nucleus (VPm) of the murine thalamus. Sensory deprivation was done by whisker plucking, and synaptic connectivity was determined by whole-cell patch-clamp record...
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PMID: 19074025
PDF is available here.
PDF is available here.
Journal of Neuroscience (28)49 2008
Abstract
We show that single whisker stimulation also evokes symmetrical areas of suprathreshold and subthreshold neuronal activation that spread extensively away from peak activity, effectively ignoring cortical borders by spilling deeply into multiple cortical territories of different modalities (auditory,...
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PMID: 19052219
PDF is available here.
PDF is available here.
Journal of Neuroscience (28)49 2008
Abstract
We examined this question using patch recordings of neurons in the barrel cortex of anesthetized rats while repetitively stimulating the principal whisker. We found that inhibition adapts more than excitation, causing the balance between them to shift toward excitation. A comparison of the latency o...
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PMID: 19052224
PDF is available here.
PDF is available here.
Journal of Neuroscience (28)49 2008
Abstract
We have previously reported that mGluR5 signaling via PLC-beta1 regulates the development of whisker patterns within S1 (barrel) cortex of mice (Hannan et al., 2001). However, whether these defects arise from the loss of postsynaptic mGluR5 signaling, and whether the level of mGluR5 is important for...
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PMID: 19052194
PDF is available here.
PDF is available here.
Abstract
We show that heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2 (HS3ST-2) is a marker for specific subsets of TrkC-expressing cutaneous low-threshold mechanosensory and proprioceptive mechanosensory neurons. Two-color in situ analysis revealed that almost all HS3ST-2 signals colocalized with TrkC...
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PMID: 18839409
PDF is available here.
PDF is available here.
Journal of Neurophysiology (100)5 2008
Abstract
We induced active whisking in anesthetized rats, monitored the movement of whiskers across surfaces, and concurrently recorded from trigeminal ganglion (TG) neurons. We show that tactile information is transmitted through high-frequency micromotions superimposed on whisking macro motions. Consistent...
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PMID: 18799602
PDF is available here.
PDF is available here.
Journal of Neuroscience (28)44 2008
Abstract
We used field potential, single-unit, and intracellular recordings to show that, although cells in the intermediate layers of the superior colliculus respond relatively effectively to single whiskers, the cells respond much more robustly to simultaneous, or nearly simultaneous, wide-field (multiwhis...
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PMID: 18971463
PDF is available here.
PDF is available here.
Journal of Neuroscience (28)44 2008
Abstract
We directly measure thalamic firing synchrony and its stimulus-induced modulation over time, using simultaneous single unit recordings from individual thalamic barreloids in the rat somatosensory whisker/barrel system. Employing whisker deflections varying in velocity or frequency and a cross-correl...
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PMID: 18971458
PDF is available here.
PDF is available here.
Abstract
We evaluated this issue at the peripheral level in enucleated rats. Whisker muscles in enucleated rats 160 days of age or older showed increased cytochrome oxidase activity, capillary density, motor plate size, and amplitude of evoked field potentials as compared with their control counterparts. Suc...
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PMID: 18838691
PDF is available here.
PDF is available here.