Abstract
Mechanical signals can play a key role in regulating the chondrogenic differentiation of mesenchymal stem cells (MSCs). The objective of this study was to determine if the long-term application of cyclic hydrostatic pressure could be used to improve the functional properties of carti...
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PMID: 21783134
PDF is available here.
Abstract
We hypothesized that N-arachidonoyl-serotonin (AA-5-HT) and its analogs could be endogenously present in those tissues that have high contents of serotonin. We investigated the endogenous presence of N-acyl serotonins in different parts of the gastro-intestinal tract of pigs and mice. We discovered...
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PMID: 21798367
PDF is available here.
Circulation (124)11 Suppl 2011
Abstract
We previously showed that adenoviral-delivered overexpression of an endogenous inhibitor, the tissue inhibitor of metalloproteinases-3 (TIMP-3), significantly retarded intimal thickening in short-term autologous porcine arteriovenous interposition grafts (28 days). However, it is essential to determ...
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PMID: 21911803
PDF is available here.
Abstract
During laparoscopic abdominal hernia repair (LAHR) there is a discrepancy in relative position of mesh and fixation points during the procedure (while abdominal cavity is distended with gas) and afterwards. Therefore, after the surgery the prosthesis becomes corrugated, and tension d...
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PMID: 21991846
PDF is available here.
Abstract
These results provide additional information on PRRSV entry into Marc-145 cells....
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PMID: 21998958
PDF is available here.
Abstract
Mucosal surfaces, such as the vaginal epithelium, are natural barriers to infection that are constantly exposed to bacteria and viruses, and are therefore potential sites of entry for numerous pathogens. The vaginal epithelium can be damaged mechanically, e.g. by the incorrect use of objects such as...
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PMID: 21942546
PDF is available here.
Abstract
We aimed to determine how these two molecules modify pig kidney Na,K-ATPase. Oleic and linoleic acids did not modify reactions involving the E(1) (Na(+)) conformations of the Na,K-ATPase. In contrast, K(+) dependent reactions were strongly modified after treatment. Oleic and linoleic acids were foun...
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PMID: 21767529
PDF is available here.
Hui-Ling HL Yen,
Chi-Hui CH Liang,
Chung-Yi CY Wu,
Heather L HL Forrest,
Angela A Ferguson,
Ka-Tim KT Choy,
Jeremy J Jones,
Diana Dik-Yan DD Wong,
Peter Pak-Hang PP Cheung,
Che-Hsiung CH Hsu,
Olive T OT Li,
Kit M KM Yuen,
Renee W Y RW Chan,
Leo L M LL Poon,
Michael C W MC Chan,
John M JM Nicholls,
Scott S Krauss,
Chi-Huey CH Wong,
Yi Y Guan,
Robert G RG Webster,
Richard J RJ Webby and
Malik M Peiris
Abstract
We evaluated the direct-contact and respiratory-droplet transmissibility in ferrets of representative swine influenza viruses of different lineages obtained through a 13-y surveillance program in southern China. Whereas all viruses studied were transmitted by direct contact with varying efficiency,...
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PMID: 21825167
PDF is available here.
Abstract
Background- Functional tricuspid regurgitation (TR) is increasingly recognized as a source of morbidity. Current repair strategies focus on annular remodeling because annular dilatation is common in patients with TR. Although papillary muscle (PM) displacement is recognized in functional mitral regur...
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PMID: 21810662
PDF is available here.
Abstract
Delivery of a high ratio of plasma to packed red blood cells to patients who require massive transfusion is associated with improved survival. Hemorrhagic shock causes increased production of pro-inflammatory cytokines. These are associated with late morbidity and mortality. The use of fresh frozen p...
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PMID: 21825929
PDF is available here.
Abstract
Laser Doppler Imaging (LDI) is a noninvasive means to measure blood flow through the superficial skin capillary plexus using flux units. Our objective was to determine the ability of LDI of the skin to detect and quantify rapid, severe hemorrhage.
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PMID: 21825944
PDF is available here.
Abstract
To demonstrate the watertight seal created by the new wide-angle Landers trunkless temporary keratoprosthesis (T-TKP).
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PMID: 21825190
PDF is available here.
Abstract
To report a case of button battery-induced alkaline burn injury of the cornea and conjunctiva, with experimental findings of local damage.
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PMID: 21882589
PDF is available here.
Abstract
It has been shown that calix[4]arene C-99 inhibited myosin subfragment-1 ATPase of myometrium. This inhibition is noncompetitive as to ATP and Mg2+. At the same time, this compound reduces the seeming enzymatic hydrolysis maximum rate of nucleoside triphosphate with respect to ATP and Mg2+. With the...
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PMID: 21805859
PDF is available here.
Abstract
We suppose that the way of enzyme activation is prevalent in the condition of the moderate formation of nitric oxide and in the absence of hyper(over)production of reactive oxygen species....
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PMID: 21805860
PDF is available here.
Abstract
The present study was initiated to develop a sensitive and highly selective method for the simultaneous quantification of the nerve agent VX (O-ethyl S-[2(diisopropylamino)ethyl] methylphosphonothioate) and its toxic metabolite (EA-2192) in blood and plasma samples in vivo and in vit...
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PMID: 21862421
PDF is available here.
Abstract
We aimed to determine the effect of using alternate LP reconstitution acids on physiologic parameters, blood loss, coagulation, oxidative DNA damage, and proinflammatory cytokines in a polytrauma and hemorrhagic shock model....
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PMID: 21818011
PDF is available here.
Abstract
Although the immunologic benefits of laparoscopic surgery have been established, effects from hand-assisted (HA) surgery have not been investigated thoroughly. We hypothesized that the HA approach maintains the immunologic advantage of laparoscopic surgery compared with the open (O) approach.
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PMID: 21741520
PDF is available here.
Abstract
The purpose of this study was to present a radiofrequency (RF) endovascular occlusion device (ie, Habib VesCoag Catheter; EMcision Ltd, London, UK) and to evaluate safety and efficacy of the device for complete occlusion of normal porcine vessels.
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PMID: 21741521
PDF is available here.
Abstract
The diverse information of efficacy of hemostatic products, obtained from different military laboratories using different models, has made it difficult to ascertain the true benefit of new hemostatic agents in military medicine. The aim of this study was to recommend a standard hemorrhage model for e...
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PMID: 21795871
PDF is available here.
Abstract
Activation of complement system has been associated with tissue injury after hemorrhage and resuscitation in rats and swine. This study investigated whether administration of human recombinant decay-accelerating factor (DAF; a complement regulatory protein that inhibits classical and alternative path...
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PMID: 21795874
PDF is available here.
Abstract
Noncompressible hemorrhage from central vascular injuries remains the leading cause of preventable death in modern combat. This report introduces a large animal model of noncompressible torso hemorrhage, which permits assessment of the various approaches to this problem.
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PMID: 21795889
PDF is available here.
Abstract
The phytochemical analysis indicated that total phenolic, flavonoid, and condensed tannin contents in the extract were 45.21 +/- 0.96 mg gallic acid equivalents/g extract, 15.39 +/- 0.58 mg catechin equivalents/g extract, and 4.90 +/- 0.20 catechin equivalents/g extract, respectively. In addition, t...
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PMID: 21780550
PDF is available here.
Abstract
The mechanism of action of non-steroidal anti-inflammatory drugs (NSAIDs), to which ketoprofen belongs, is based on their cyclo-oxigenase (COX) inhibiting action, concerning both subtype COX-1 constitutive isoform and COX-2 inducible isoform. Ketoprofen administration may be carried out by oral and p...
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PMID: 21780552
PDF is available here.
Abstract
We sampled 161 feral pigs in eastern North Carolina, USA, to determine the prevalence and antimicrobial resistance profile of Clostridium difficile and Salmonella. Seven (4.4%) and eight (5.0%) pigs tested positive for C. difficile and Salmonella, respectively, highlighting the importance of determin...
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PMID: 21719851
PDF is available here.
Abstract
These results suggest that the wild boar could be a chlamydia reservoir and may acquire chlamydiae independent of contacts with the domestic pig....
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PMID: 21719838
PDF is available here.
Abstract
We investigated the hypothesis that aortic valve biomechanics participate in the regulation of both 5HTR expression and interrelated extracellular matrix remodeling events....
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PMID: 21718840
PDF is available here.
Abstract
In a porcine model, we investigated the impact of sudden stent graft occlusion of thoracic intercostal arteries after open lumbar segmental artery (SA) ligation.
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PMID: 21718839
PDF is available here.
Abstract
We examined representations and risk perceptions associated with swine flu amongst 120 Malaysian pig farmers. Thirty-seven per cent of respondents felt at particular risk of infection, two-thirds were somewhat or very concerned about being infected. Those respondents who were the most anxious believ...
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PMID: 21936262
PDF is available here.
Abstract
The susceptibility to an initial challenge and a re-challenge inoculation with Actinobacillus pleuropneumoniae was analysed in pigs that were treated with antimicrobials of different efficacies following the first exposure to A pleuropneumoniae. In brief, 30 nine-week-old specific pathogen-free pigs...
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PMID: 21737462
PDF is available here.
Abstract
We purified activated chymotrypsin C from porcine pancreas, and identified its three active forms. Active chymotrypsin C was found to be different in the length of its 13-residue activation peptide due to carboxydipeptidase (present in the pancreas) degradation or autolysis of the activated chymotry...
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PMID: 21659382
PDF is available here.
Abstract
This study investigated methods of increasing the effectiveness of preservation solutions. Recently, it has been reported that solution effectiveness can be improved by the addition of prolactin (PRL). This study determines the effect of prolactin (PRL) on the amount and release rate of alanine amino...
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PMID: 21716192
PDF is available here.
Abstract
We have designed and produced a modular, recombinant resilin-like polypeptide bearing both mechanically active and biologically active domains to create novel biomaterial microenvironments for engineering mechanically active tissues such as blood vessels, cardiovascular tissues, and vocal folds. Pre...
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PMID: 21553895
PDF is available here.
Abstract
We performed this study to evaluate the hemostatic efficacy of the FAST Dressing in treating a grade V liver injury in noncoagulopathic swine.
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PMID: 21817977
PDF is available here.
Abstract
Advanced hemostatic dressings perform superior to standard gauze (SG) in animal hemorrhage models but require 2 minutes to 5 minutes application time, which is not feasible on the battlefield.
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PMID: 21817978
PDF is available here.
Abstract
We hypothesized that prolonged use of TIVS in SMA injuries would jeopardize EC integrity....
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PMID: 21817984
PDF is available here.
Abstract
A method for the determination of malondialdehyde (MDA) concentrations in specimens of animal tissues and feed has been developed using high performance liquid chromatography. The MDA concentration in acidified urine samples was determined after its conversion with 2,4-dinitrophenylh...
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PMID: 21727037
PDF is available here.
M M Schmidt,
K D KD Winter,
V V Dantzer,
J J Li,
P M PM Kragh,
Y Y Du,
L L Lin,
Y Y Liu,
G G Vajta,
P T PT Sangild,
H H Callesen and
J S JS Agerholm
Abstract
We report on mortality of cloned transgenic or non-transgenic piglets produced as part of several investigations. Large White (LW) sows (n = 105) received hand-made cloned LW or minipig blastocysts and delivered either spontaneously or after prostaglandin induction followed by either Caesarean secti...
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PMID: 21635813
PDF is available here.
Abstract
Two experiments were performed in the present study that demonstrated that boar spermatozoa are capable of surviving rapid cooling rates within a range of 15-5 °C before freezing. Boar ejaculates diluted in Beltsville thawing solution (BTS) (1:1, v/v) were held at 17-20 °C and shipped over a 24-h t...
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PMID: 21635817
PDF is available here.
Abstract
The shelf life of fresh Italian pork sausages packed in modified atmosphere was studied. Samples were packed using different levels of oxygen (high and low) with different levels of carbon dioxide (high-low) in the atmospheres headspace and were stored at 4 °C for 9 days. Microbial,...
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PMID: 21693619
PDF is available here.
Abstract
Wound exudate and bleeding could be easily seen when using gauze and green foam, but were not visible under the black foam. Such visibility facilitates monitoring of the wound status. No difference was found in the quantity or characteristics of the granulation tissue formed under the green foam or...
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PMID: 21727880
PDF is available here.
Abstract
These results suggest that the active site region may be amongst the earliest parts of the structure to unfold. Detergent-solubilized Na,K-ATPases from the two sources show the similar differences in thermal stability as the membrane-bound species, but inactivation occurs at a lower temperature for...
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PMID: 21712026
PDF is available here.
Dhanasekaran Vijaykrishna,
Gavin J D Smith,
Oliver G Pybus,
Huachen Zhu,
Samir Bhatt,
Leo L M Poon,
Steven Riley,
Justin Bahl,
Siu K Ma,
Chung L Cheung,
Ranawaka A P M Perera,
Honglin Chen,
Kennedy F Shortridge,
Richard J Webby,
Robert G Webster,
Yi Guan and
J S Malik Peiris
Abstract
We quantify the epidemiological, genetic and antigenic dynamics of SwIV in Hong Kong using a data set of more than 650 SwIV isolates and more than 800 swine sera from 12 years of systematic surveillance in this region, supplemented with data stretching back 34 years. Intercontinental virus movem...
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PMID: 21614079
PDF is available here.
Jennifer Lee JL Young,
Elham E Khanifar,
Navneet N Narula,
Cervando Gerardo CG Ortiz-Vanderdys,
Surendra Babu SB Kolla,
Donald Lowell DL Pick,
Petros George PG Sountoulides,
Oskar Grau OG Kaufmann,
Kathryn Elizabeth KE Osann,
Victor Buu VB Huynh,
Adam Geoffrey AG Kaplan,
Lorena Aurora LA Andrade,
Michael Ken MK Louie,
Elspeth Marguerita EM McDougall and
Ralph Victor RV Clayman
Abstract
To our knowledge the optimal freeze cycle length in renal cryotherapy is unknown. Ten-minute time based freeze cycles were compared to temperature based freeze cycles to -20C.
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PMID: 21600606
PDF is available here.
Abstract
We designed an experimental model of renal ischemia-reperfusion to evaluate the preemptive effect of intravenous sildenafil according to the dose administered (0.7 vs 1.4 mg/kg) and the time of administration (30 minutes before ischemia or during ischemia).
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PMID: 21600605
PDF is available here.
Abstract
In organic farming animal welfare is one important aspect included in the internationally agreed organic principles of health, ecology, fairness and care (IFOAM 2006), reflecting expectation of consumers and farmers. The definition of organic animal welfare includes-besides traditional terms of anima...
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PMID: 21559784
PDF is available here.
Abstract
Chronic exercise attenuates coronary artery disease (CAD) in humans largely independent of reductions in risk factors, thus major protective mechanisms of exercise are directly within the coronary vasculature. Further, tight control of diabetes risk factors, e.g. blood glucose, can b...
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PMID: 21596923
PDF is available here.