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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Humans (0):
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Humans
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Dementia is associated with increased rates and often poorer outcomes of hospitalization, including worsening cognitive status. New evidence is needed to determine whether some admissions of persons with dementia might be potentially preventable.
To determine whether...
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PMID: 22235087
PDF is available here.
PDF is available here.
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Clinical practice guidelines recommend maintaining serum potassium levels between 4.0 and 5.0 mEq/L in patients with acute myocardial infarction (AMI). These guidelines are based on small studies that associated low potassium levels with ventricular arrhythmias in the pre-β-blocker...
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PMID: 22235086
PDF is available here.
PDF is available here.
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Marijuana smoke contains many of the same constituents as tobacco smoke, but whether it has similar adverse effects on pulmonary function is unclear.
To analyze associations between marijuana (both current and lifetime exposure) and pulmonary function....
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PMID: 22235088
PDF is available here.
PDF is available here.
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Ugeskrift for laeger (173)50 2011
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Links are well established between both family history of diabetes and reduced birthweight and increased risk of diabetes in adulthood.
1) To investigate the influence of parental history of type 2 diabetes (T2DM) on offspring birthweight and adult offspring glucose t...
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PMID: 21916855
PDF is available here.
PDF is available here.
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We present the first analysis of age-at-onset in the NIMH LOAD sample that allows for both a multilocus trait model and genetic heterogeneity among the contributing sites, while at the same time accommodating age censoring, effects of known genetic covariates, and full pedigree and marker informatio...
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PMID: 21812099
PDF is available here.
PDF is available here.
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We experienced a case of a peritoneal dialysis patient with chronic hepatitis C who was successfully treated with PEG-IFN monotherapy. A 50-year old man was undergoing peritoneal dialysis because of diabetic nephropathy. Considering that his HCV genotype was 2, we decided to treat him with PEG-IFN a...
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PMID: 21873827
PDF is available here.
PDF is available here.
Aging and Mental Health (15 Suppl 1) 2011
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We reported that vitamin K₃ (menadione, 2-methyl-1,4-naphthoquinone) (compound 2) inhibits the activity of human mitochondrial DNA polymerase γ (pol γ). In this study, we investigated the inhibitory effects (IEs) of vitamin K3 and its derivatives, such as 1,4-naphthoquinone (compound 1) and 1,2-...
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PMID: 21837358
PDF is available here.
PDF is available here.
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Biochemical Pharmacology (82)11 2011
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We analyzed the effects of IFN-α2b and TGF-β1 treatments on Wnt/β-catenin pathway, Smads proteins levels, β-catenin/TCF4/Smads interaction and proliferation and apoptotic death in HepG2/C3A and Huh7 cell lines. IFN-α2b and TGF-β1 attenuated Wnt/β-catenin signal by decreasing β-catenin and Fr...
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PMID: 21843516
PDF is available here.
PDF is available here.
Journal of Neurochemistry (119)5 2011
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We have used neuroblastoma cells expressing NDM29 at its basal level (Mock cells) or at 5.4-fold higher levels (S1 cells) to investigate whether a functional differentiation correlates with morphological and biochemical development induced by NDM29 expression. First, analyzing the expression of spec...
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PMID: 21933186
PDF is available here.
PDF is available here.
Journal of Neurochemistry (119)5 2011
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We have investigated presenilin (PS)-dependent secretase-mediated processing of nectins in PS1 KO cells and primary hippocampal neurons. The loss of PS1/γ-secretase activity delayed the processing of nectin-1 and caused the accumulation of its full-length and C-terminal fragments. Over-expression o...
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PMID: 21910732
PDF is available here.
PDF is available here.
Clinical Science (122)2 2012
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We aim to provide an overview of the vast literature on angiogenesis and anti-angiogenesis factors in pre-eclampsia that have been published over the last decade. We introduce work from basic research groups who have focused on the pathophysiological basis of the disease. Furthermore, we review stud...
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PMID: 21929511
PDF is available here.
PDF is available here.
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We have discovered that other cellular stressors are integrated with glucocorticoid signaling through a new hormone-independent phosphorylation site, Ser134, on the human glucocorticoid receptor (GR). Ser134 phosphorylation is induced by a variety of stress-activating stimuli in a p38 mitogen-activa...
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PMID: 21930780
PDF is available here.
PDF is available here.
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Breast Cancer Research (Online Edition) (13 Suppl 2) 2011
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Biochemical Pharmacology (82)10 2011
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I review the form and function of TAM and discuss the role of NF-κB activation in TAM in carcinogenesis....
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PMID: 21080151
PDF is available here.
PDF is available here.
Cancer Research (71)22 2011
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We developed a curated database of 88 nuclear receptor cistrome data sets and other associated high-throughput data sets including 121 collaborating factor cistromes, 94 epigenomes, and 319 transcriptomes. Through integrative analysis of the curated nuclear receptor ChIP-chip/seq data sets, we disco...
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PMID: 21940749
PDF is available here.
PDF is available here.
Journal of Biological Chemistry (286)44 2011
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We report here that testicular nuclear receptor 4 (TR4), a member of the nuclear receptor family, modulates DNA repair specifically through the transcription-coupled (TC) NER pathway but not the global genomic NER pathway. The level of Cockayne syndrome B protein (CSB), a member of the TC-NER pathwa...
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PMID: 21918225
PDF is available here.
PDF is available here.
Federal Register (76)214 2011
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This final rule sets forth updates to the home health prospective payment system (HH PPS) rates, including: the national standardized 60-day episode rates; the national per-visit rates; and the low utilization payment amount (LUPA) under the Medicare PPS for home health agencies effe...
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PMID: 22059280
PDF is available here.
PDF is available here.
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We summarize our current understanding of PD-1 and its ligands ranging from discovery to clinical significance....
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PMID: 21061197
PDF is available here.
PDF is available here.
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We present the results of studies confirming the importance of DCI to HCV pathogenesis. Computational models incorporating proteomic data from HCV patient liver biopsy specimens recapitulated our original predictions regarding DCI and link HCV-associated alterations in cellular metabolism and liver...
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PMID: 21917952
PDF is available here.
PDF is available here.
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Subacute sclerosing panencephalitis (SSPE) is a fatal sequela associated with measles and is caused by persistent infection of the brain with measles virus (MV). The SI strain was isolated in 1976 from a patient with SSPE and shows neurovirulence in animals. Genome nucleotide sequence analyses showed...
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PMID: 21917959
PDF is available here.
PDF is available here.
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We sought to characterize the modular sequence in the GaLV Env CTD required for this restriction in the presence of Vpu. Using a systematic mutagenesis scan, we determined that the motif that makes GaLV Env sensitive to Vpu is INxxIxxVKxxVxRxK. This region in the CTD of GaLV Env is predicted to form...
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PMID: 21917962
PDF is available here.
PDF is available here.
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We demonstrate that the RNA-binding activity of NP is necessary for stabilization of cRNA, whereas, surprisingly, homo-oligomerization of NP is not essential. However, both RNA binding and homo-oligomerization activities are essential for genome replication....
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PMID: 21917965
PDF is available here.
PDF is available here.
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The liver-specific microRNA miR-122 is required for efficient hepatitis C virus (HCV) RNA replication both in cell culture and in vivo. In addition, nonhepatic cells have been rendered more efficient at supporting this stage of the HCV life cycle by miR-122 expression. This study investigated how miR...
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PMID: 21917968
PDF is available here.
PDF is available here.
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We describe the magnitude, kinetics, and nature of the virus-specific T cell response using intracellular gamma interferon (IFN-γ) staining and fluorochrome-labeled major histocompatibility complex (MHC) class I-peptide complexes. We demonstrate that influenza virus-infected patients develop recall...
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PMID: 21917970
PDF is available here.
PDF is available here.
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We report that BST-2 antibody treatment facilitates virus release from BST-2(+) cells by interfering with the tethering activity of BST-2. BST-2 antibodies were unable to release already tethered virions and were most effective when added early during virus production. BST-2 antibody treatment did n...
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PMID: 21917971
PDF is available here.
PDF is available here.
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We provide an overview of the field of epigenetics in relation to ARTs....
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PMID: 21848664
PDF is available here.
PDF is available here.
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J. Neurochem. (2011) 119, 507-520. ABSTRACT: In vitro blood-brain barrier (BBB) models often consist of brain microvascular endothelial cells (BMECs) that are co-cultured with other cells of the neurovascular unit, such as astrocytes and neurons, to enhance BBB properties. Obtaining primary astrocyte...
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PMID: 21854389
PDF is available here.
PDF is available here.
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We studied the localization, activation and function of protease-activated receptor 1 (PAR-1) at the CNS synapse utilizing rat brain synaptosomes and slices. Confocal immunofluoresence and transmission electron microscopy in brain slices with pre-embedding diaminobenzidine (DAB) immunostaining found...
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PMID: 21854391
PDF is available here.
PDF is available here.
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We hypothesized that, with hypertension, localized iNOS inhibition would restore vasodilation in response to NO-dependent stimuli, and iNOS expression would be increased and phosphorylated vasodilator-stimulated phosphoprotein would be decreased. For, in vivo protocols, 4 intradermal microdialysis f...
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PMID: 21931069
PDF is available here.
PDF is available here.
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We established a new limited sampling strategy to assess CYP3A activity and evaluated the time course of reversible (voriconazole) and irreversible (ritonavir) CYP3A inhibition. In this randomized trial, two groups, each with eight healthy participants, received CYP3A inhibitors voriconazole or riton...
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PMID: 21937987
PDF is available here.
PDF is available here.
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