Abstract
We raised polyclonal antibodies by immunizations of rabbits. These antibodies specifically identified pro-MMP-9 in incisional skin wound extracts from mice when used for Western blotting. Immunohistochemical analysis of paraffin embedded skin wounds from mice showed that MMP-9 protein was localized...
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PMID: 20214994
PDF is available here.
Abstract
We tested samples from small mammals from 3 villages, including Soromba, where in 2009 a British citizen probably contracted a lethal Lassa virus infection. We report the isolation and genetic characterization of Lassa virus from an area previously unknown for Lassa fever....
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PMID: 20587185
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Abstract
Helminths, 3 cestode and 8 nematode species, including 2 new genera, 5 new species, and 1 putative new species, of nematode were collected from the digestive tracts of 23 Lorentzimys nouhuysi (Murinae; Hydromyini) from Papua New Guinea. Odilia wauensis n. sp. (Heligmonellidae) most closely resembles...
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PMID: 20557207
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Abstract
The present investigation deals with the evaluation of antifilarial efficacy of liposome entrapped antiwolbachial antibiotics doxycycline and rifampicin (5 doses at 10 mg/kg, subcutaneously for 15 days) alone and/or in combination with standard filaricide diethylcarbamazine (DEC) against human lymph...
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PMID: 19954408
PDF is available here.
Abstract
We propose MWV as a tentative novel species in the Lassa-lymphocytic choriomeningitis virus complex, based on its isolation from a novel rodent species and its genetic and serological characteristics....
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PMID: 20071489
PDF is available here.
Abstract
After passage, HV positive mouse body mite group out of both 5 and 10 mites in the sixth generation, OT positive mouse body mite group out of the 10 mites in the sixth generation, both HV and OT positive mouse body mite group out of 1 mite in the fifth and sixth generation, both HV and OT positive m...
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PMID: 20654145
PDF is available here.
Abstract
We asked whether the occurrence and the extent of host gender-biased parasitism vary among higher parasite taxa, among individual species within these taxa and within parasite species among localities. To answer this question, we studied prevalence, abundance, species richness and the level of aggre...
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PMID: 19835648
PDF is available here.
David J Hughes,
Anja Kipar,
Steven G Milligan,
Charles Cunningham,
Mandy Sanders,
Michael A Quail,
Marie-Adele Rajandream,
Stacey Efstathiou,
Rory J Bowden,
Claude Chastel,
Malcolm Bennett,
Jeffery T Sample,
Bart Barrell,
Andrew J Davison and
James P Stewart
Abstract
Two novel gammaherpesviruses were isolated, one from a field vole (Microtus agrestis) and the other from wood mice (Apodemus sylvaticus). The genome of the latter, designated wood mouse herpesvirus (WMHV), was completely sequenced. WMHV had the same genome structure and predicted gene content as mur...
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PMID: 19940063
PDF is available here.
Abstract
Our findings show that, after an environmental disaster, the behaviour of helminth species might be related to their pre-catastrophe presence, their biological cycles, the host's immunological condition, the change of host dynamics, the direct effects of the perturbation, and the processes related t...
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PMID: 19580689
PDF is available here.
Abstract
We have previously developed a model of near-term intra-uterine hypoxia producing significant neonatal mortality (37%) in a small laboratory animal - the spiny mouse - which has precocial offspring at birth. The aim of the present study was to determine if this insult resulted in the appearance of b...
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PMID: 19590246
PDF is available here.
Abstract
This paper presents data on the detection of hantavirus in the excretory organs of Apodemus mice which are natural carriers of pathogenic hantaviral serotypes in the Primorye Region. Acute infection periods were detected in naturally infected rodents with the highest hantavirus dissemination to the...
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PMID: 20455471
PDF is available here.
Abstract
We suppose that Asian race can be considered as independent allopatric species. This is supported by following evidences: high divergence level (which proposes more than 1 mya of divergent evolution) between races, absence of common haplotypes and hiatus between main peaks of mismatch distribution,...
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PMID: 21090235
PDF is available here.
Abstract
This study was initiated to establish whether any South African ethnomedicinal plants (indigenous or exotic), that have been reported to be used traditionally to repel or kill mosquitoes, exhibit effective mosquito repellent properties.
Extracts of a selection of South African taxa were tested for r...
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PMID: 21029442
PDF is available here.
Abstract
We investigated the association between chronotype and Fos expression during the day and night in three major nuclei in the basal forebrain (BF) cholinergic (ACh) arousal system - medial septum (MS), vertical and horizontal diagonal band of Broca (VDB and HDB respectively) -, and whether neural acti...
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PMID: 19837140
PDF is available here.
Abstract
A survey to determine the geographical distribution and relative abundance of potential vectors of scrub typhus was conducted from October to November 2006 at 13 localities throughout the Republic of Korea. Apodemus agrarius accounted for 97.6% (80/82) of all rodents, while only 2 Myodes regulus (2/...
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PMID: 19967086
PDF is available here.
Abstract
We used artificial seeds to partition the effects of seed size, tannin content, and nutrient content on scatter-hoarding rodents in a natural pine forest in Northwest Yunnan, China. Apodemus, a common genus of Old World rodents, consistently consumed small seeds in situ but removed medium-sized seed...
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PMID: 19967858
PDF is available here.
Abstract
Four US soldiers acquired hemorrhagic fever with renal syndrome while training near the Demilitarized Zone, South Korea, in 2005. Hantaan virus sequences were amplified by reverse transcription-PCR from patient serum samples and from lung tissues of striped field mice (Apodemus agrarius) captured at...
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PMID: 19891878
PDF is available here.
Abstract
We report that peroxidase cyt c/CL complexes can utilize free fatty acid hydroperoxides (FFA-OOH) at exceptionally high rates that are approximately 3 orders of magnitude higher than for H(2)O(2). Similarly, peroxidase activity of murine liver mitochondria was high with FFA-OOH. Using EPR spin trapp...
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PMID: 19627079
PDF is available here.
Abstract
Two bacterial strains, Fuji 18-1(T) and Fuji 23-1(T), were isolated from the blood of the small Japanese field mouse (Apodemus argenteus) and the large Japanese field mouse (Apodemus speciosus), respectively, specimens of which were captured in the forest of Mount Fuji, Japan. Phenot...
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PMID: 19656930
PDF is available here.
I-Ju IJ Lin,
Zhuo Z Zhou,
Valerie J VJ Crusselle-Davis,
Babak B Moghimi,
Kunjal K Gandhi,
Archana A Anantharaman,
Dorjan D Pantic,
Suming S Huang,
Giridhararao G Jayandharan,
Li L Zhong,
Arun A Srivastava and
Jörg J Bungert
Abstract
We show here that the protein levels of upstream stimulatory factor (USF) increase during differentiation of murine erythroleukemia (MEL) cells. USF was subject to degradation by the Ca(2+)-dependent protease m-calpain in undifferentiated but not in differentiated MEL cells. Treatment of MEL cells w...
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PMID: 19491096
PDF is available here.
Abstract
A new series of 20 quinoline derivatives possessing triazolo, ureido and thioureido substituents have been synthesized and their antimycobacterial properties have been evaluated. Compounds 10, 22 and 24 inhibited Mycobacterium tuberculosis H37Rv up to 96%, 98% and 94% respectively, a...
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PMID: 19457676
PDF is available here.
Abstract
In this investigation on endoparasites (helminths) and ectoparasites of the Nile rat (Arvicanthis niloticus Desmarest, 1822), a total of 220 Nile rats were trapped from different regions of Sudan during the period January 2003-January 2006. Examination of different tissues, identific...
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PMID: 21392288
PDF is available here.
Abstract
We analysed 3 independently collected datasets of fully censused helminth burdens in wood mice, Apodemus sylvaticus, testing the a priori hypothesis of Behnke et al. (2005) that the presence of the intestinal nematode Heligmosomoides polygyrus predisposes wood mice to carrying other species of helmi...
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PMID: 19486546
PDF is available here.
Abstract
We show that CTLA-4-induced suppression of IL-2 production correlates with rapid destabilization of immunological synapse (IS) formation in murine normal T cell clones. Overexpression of Spa-1, a Rap-1-specific GTPase activating protein (GAP), abolished both Rap-1 activation and IL-2 suppression ind...
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PMID: 19490760
PDF is available here.
Abstract
Several hypotheses concerning variations in the frequency of some elementary events determining the formation and reorganization of mammalian B chromosomes are proposed on the basis of the data on their number, morphology, and DNA composition in Korean field mice Apodemus peninsulae (Mammalia, Roden...
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PMID: 19507698
PDF is available here.
Abstract
We investigated geographic variation in morphological traits of the large Japanese field mouse (Apodemus speciosus) from the Izu Island Group, Japan. There was sexual dimorphism in external characters and cranial measurements; hence, these were considered in subsequent analyses. There was geographic...
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PMID: 19798920
PDF is available here.
Abstract
A water-insoluble, detergent-soluble, surface-associated glycoprotein, designated as Dssd1, was found to induce microfilaria clearance in Mastomys coucha implanted with Setaria digitata. Intraperitoneal implantation of adult female worms of S. digitata in M. coucha could induce microfilaraemia lasti...
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PMID: 18922206
PDF is available here.
Abstract
2 strains virus (ZLS6-11 and ZLS-12) were successfully isolated from 7 positive lung samples of mice and were identified as HTNV by anti-McAb and phylogenetic analysis. With sequence compation,we found that 2 strains with complete M and S segment had higher homology with HTN-type strains than with o...
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PMID: 19565882
PDF is available here.
Yong-Zhen Zhang,
Xue Dong,
Xin Li,
Chao Ma,
Hai-Ping Xiong,
Guang-Jie Yan,
Na Gao,
Dong-Mei Jiang,
Ming-Hui Li,
Lu-Ping Li,
Yang Zou and
Alexander Plyusnin
Abstract
We conducted a study to characterize etiologic agents of the outbreaks and clarify the origin of hantaviruses causing infections in humans and laboratory animals. Immunoglobulin (Ig) M or IgG antibodies against Seoul virus (SEOV) were detected in the serum samples of all 8 patients. IgG antibodies a...
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PMID: 19193263
PDF is available here.
Abstract
We present in this review show clearly that unintentional Helicobacter infection has the potential to significantly interfere with the reliability of research studies based on murine models. Therefore, frequent screening of rodent research colonies for Helicobacter spp. and the eradication of these...
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PMID: 19295050
PDF is available here.
Abstract
We developed a model of birth asphyxia resulting in mild neurological injury and cognitive impairment using a long-gestation species with precocial fetal development. Spiny mice (Acomys cahirinus) underwent caesarean-section delivery or 7.5 min of asphyxia at 37 days gestational age (term is 39 days...
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PMID: 19851070
PDF is available here.
Abstract
There is extensive and convincing evidence from experimental studies that interactions exist between helminths of different species during concurrent infections in laboratory rodents. Among the strongest interactions are those that arise from immune responses of the hosts. However, detecting compara...
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PMID: 20209801
PDF is available here.
Abstract
The experience in combining disinfestation and forestry engineering measures is described to achieve a long-term effect: in minimizing the number of murine rodents, which has considerably reduced the amount of poisoned baits placed into the environment when disinfestation is made in open areas.
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PMID: 19802943
PDF is available here.
Abstract
We demonstrate that A. agrarius mice transcribe two unique alternatively spliced testicular CD46 mRNA transcripts, both lacking exon 7, which differ from those described previously in other Apodemus species. The larger A. agrarius CD46 transcript has an insert between exons 10 and 11 which, if trans...
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PMID: 19371423
PDF is available here.
Abstract
Mastomys natalensis is the major pest rodent in sub-Saharan Africa. In this study, population genetic techniques were used to gain new insights into its dispersal behaviour, a critical parameter in pest management. Using 11 microsatellites, 272 individuals from a 300 ha area in Tanzania were genotyp...
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PMID: 19200138
PDF is available here.
Abstract
We infer that most of animals studied (196 out of 312, or 63%) have an individual variant of the B chromosome system. Only three mice lacked B chromosomes. New data for 44 A. peninsulae mice caught in 2000-2005 in 16 localities of seven regions of Altai, Siberia, and Pribaikal'e showed that all of t...
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PMID: 19178085
PDF is available here.
Abstract
An increasing number of Bartonella species originally isolated from small mammals have been identified as emerging human pathogens. During an investigation of Bartonella infection in rodent populations carried out in Taiwan in 2006, a total of 58 rodents were tested. It was determined that 10.3 % (6...
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PMID: 19018019
PDF is available here.
Abstract
Two new species of heligmosomoid Trichostrongylina nematodes belonging to the genera Neoheligmonella Durette-Desset, 1970 and Heligmonina Baylis, 1928 are described. They are parasitic in the small intestine of three species of Mastomys from Senegal living in sympatry: M. natalensis (Smith, 1834), M...
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PMID: 19202761
PDF is available here.
Nobuo Koizumi,
Maki Muto,
Seigo Yamamoto,
Yoshitaka Baba,
Momotoshi Kudo,
Yoshinobu Tamae,
Koji Shimomura,
Ichiro Takatori,
Akira Iwakiri,
Koji Ishikawa,
Hirotoshi Soma and
Haruo Watanabe
Abstract
We surveyed reservoir animals of leptospires in the northern part of Miyazaki Prefecture, where a cluster of human leptospirosis had occurred during the summer of 2006. Leptospira was isolated from 6 of 57 large Japanese field mice (Apodemus speciosus). The serogroups of the isolates were Autumnalis...
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PMID: 19050356
PDF is available here.
Abstract
Cytokine (interferon (IFN)-gamma, interleukin (IL)-2, IL-4, IL-5, IL-10) gene transcription in response to filarial antigens was determined in peripheral blood mononuclear cells of Brugia malayi-infected Mastomys coucha in the course of untreated and chemotherapeutically abbreviated infections. Tran...
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PMID: 18679719
PDF is available here.
Abstract
13 extracts (28%) were active in vitro with MIC-values < or = 100 microg/ml, 6 extracts showed MIC-values < or = 50 microg/ml. The root extract of Securidaca longepedunculata Fresen. (Polygalaceae) and the leaf extract of Guiera senegalensis J. F. Gmel. (Combretaceae) were able to reduce parasitaemi...
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PMID: 18638537
PDF is available here.
Abstract
We examined rhythms in one element of the circadian oscillator, the PER1 protein, in a variety of cell populations in brains of diurnal female grass rats. Every 4 h five adult female grass rats kept on a 12-h light/dark (LD) cycle were perfused and their brains were processed for immunohistochemical...
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PMID: 18692118
PDF is available here.
Abstract
A new evolutionary genetic phenomenon - increase in the number of B-chromosomes (almost threefold) accompanied by change in B chromosome morphotypes - was discovered in the Artybash population of East Asian mouse Apodemus peninsulae (Mountain Altai) over a historically short period (22 years), compa...
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PMID: 18846820
PDF is available here.
Abstract
Of the 385 persons enrolled, 29.6 per cent showed evidence of past leptospiral infection. Many locally prevalent serogroups and changing patterns of prevalence in humans were identified in the five consecutive years of the study. The major serogroups were autumnalis, louisiana, australis, and grippo...
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PMID: 19052343
PDF is available here.
Abstract
5' EST from filarial gene database has been subjected to 3' rapid amplification of cDNA ends (RACE), semi-nested PCR and PCR to obtain full-length cDNA of Brugia malayi. Full-length hexokinase gene was obtained from cDNA using gene specific primers. The elicited PCR product was cloned, sequenced and...
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PMID: 18499511
PDF is available here.
Abstract
The objective of the study was to analyze the epidemiological features of hemorrhagic fever with renal syndrome (HFRS) in Montenegro. The study included 169 cases of HFRS diagnosed in the period between 1995 and 2005 according to the clinical symptoms and serological confirmation. For the analysis o...
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PMID: 18806348
PDF is available here.
Abstract
Instability of B-chromosomes was estimated in somatic and germline cells of samples Apodemus peninsulae from different localities of the species range. In 84 out of 188 animals (45%), in cells assessed for B-chromosome mosaicism, bone marrow cells with different B-chromosome number were observed. Th...
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PMID: 18825959
PDF is available here.
Abstract
A molecular epidemiological survey was conducted to investigate the presence of pathogenic Borrelia burgdorferi sensu lato (s.l.) species in the forest areas of Zhejiang province, south-east China. A total of 182 ticks of 6 species and 200 rodents of 8 species were collected and individually examine...
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PMID: 18628499
PDF is available here.
Abstract
Our results reveal that the highest genetic diversity of HTNV is in a limited geographical region of Guizhou, and suggest that Guizhou might be a radiation centre of the present form of HTNV....
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PMID: 18632971
PDF is available here.
Abstract
These results suggest that multiple Herpetosoma species or strains are enzootic to Thailand, and that Rattus and Bandicota species are possible sources of human exposure to these parasites....
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PMID: 17904918
PDF is available here.
Abstract
Our data show eight extant lineages of Late Tertiary origin: Apodemus agrarius, A. semotus, A. peninsulae, A. speciosus, A. argenteus, A. gurkha, A. mystacinus, and A. sylvaticus. Monophyly of two European lineages (A. mystacinus and A. sylvaticus) and four Asian lineages (A. agrarius, A. semotus, A...
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PMID: 18231851
PDF is available here.
Abstract
A brief review of the arboviruses isolated In Italy is presented and discussed. Some of the Arboviruses considered in this paper are endemic in the country and are transmitted by arthropods that play actually a role of vectors, (sand flyes, hard ticks and mosquitoes); other arboviruses, sporadically...
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PMID: 18693572
PDF is available here.
Abstract
A total of 210 individuals of 13 species belonging to 4 subfamilies of Muridae imported into Japan as pets were examined; 5 species of Syphacia (Nematoda: Oxyuridae), Aspiculuris tetraptera (Nematoda: Heteroxynematidae), and Rodentolepis nana (Cestoidea: Hymenolepididae) were collected. Concurrent i...
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PMID: 18605784
PDF is available here.
Abstract
Notomys alexis (Spinifex hopping mouse) is found in the arid zone of Australia. The structure and function of the kidneys allow this species to conserve water. This study investigated the rate at which N. alexis can reduce urine volume and increase the concentration of electrolytes and solutes when...
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PMID: 17374563
PDF is available here.
Abstract
These results are in agreement with the hypothesis that prolactin is one proximate mechanism of male reproductive tactics, possibly regulating differences in male parental care....
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PMID: 18230588
PDF is available here.