Abstract
We combined a large-scale ungulate exclusion experiment with a five-year manipulation of rodent densities to quantify the impacts of three herbivore guilds (wild ungulates, domestic cattle, and rodents) on all life stages of a widespread savanna tree. We utilized demographic modeling to reveal the o...
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PMID: 21905429
PDF is available here.
Abstract
Scrub typhus, caused by antigenically disparate isolates of Orientia tsutsugamushi, is a widely distributed mite-borne human disease in the Asia Pacific region. Information regarding the heterogeneity of the immunodominant 56-kDa type-specific antigen (TSA) gene is crucial for the design and evaluati...
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PMID: 21593255
PDF is available here.
Abstract
There is increasing interest in the use of vascular targeted therapy for the treatment of non-small-cell lung cancer (NSCLC). Current approaches include antiangiogenic drugs, which prevent growth of new vessels, and tumor vascular disrupting drugs, which further compromise the functi...
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PMID: 21550553
PDF is available here.
Abstract
We conclude that a careful microscopic analysis of bone tissue and the characterization of distinctive osteonic features could give a major contribution to forensic medicine to obtain a more reliable recognition of bone findings....
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PMID: 21898971
PDF is available here.
Abstract
We detail the methodologies required to successfully generate and evaluate drill hole defects. Although performing a successful drill hole defect requires patience and dexterity, investing the time to perfect the technique will provide ample opportunity for the researcher to expand his/her particula...
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PMID: 21043001
PDF is available here.
Author(s) unavailable
Abstract
To determine sialic acids and O-acetyl groups content in Yersinia pestis and Vibrio cholerae antigens in order to establish their association with biological activity.
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PMID: 21604388
PDF is available here.
Abstract
We have made a comparative study of the sex chromosomes in 6 arvicolid species using different probes from the X and Y chromosomes of 3 species, in order to gain knowledge about intra- or interspecific preservation of euchromatic regions. Our results clearly reveal poor conservation of the euchromat...
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PMID: 20689262
PDF is available here.
Abstract
The development of the DNA microarray technique facilitated systematic studies of the modulation of gene function. Considerable attention has been focused on members of the growth factor family to elucidate the main regulators of oocyte maturation and ovarian follicle rupture. Among these growth fact...
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PMID: 21916103
PDF is available here.
Abstract
The incidence of cutaneous leishmaniasis in northern Israel began to rise in 2000, peaking at 41.0 per 100,000 in the Kinneret subdistrict during the first half of 2003.
To examine the morbidity rates of CL in northern Israel during the period 1999-2003, which would indicate whether new endemic area...
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PMID: 21243862
PDF is available here.
Abstract
Stroke is the third leading cause of death, after myocardial infarction and cancer, and the leading cause of permanent disability in Western countries. Although anti-inflammatory drugs have shown very promising results in preclinical rodent studies, they appeared to be ineffective against stroke in...
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PMID: 20979930
PDF is available here.
Abstract
Vasopressin (VP) secreted from parvocellular neurons of the hypothalamic paraventricular nucleus (PVN) stimulates pituitary adrenocorticotropic hormone (ACTH) secretion, through interaction with receptors of the V1b subtype (V1bR) in the pituitary corticotroph, mainly by potentiating the stimulatory...
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PMID: 18655869
PDF is available here.
Abstract
Huntington's disease (HD) is neither a fatal hereditary neurodegenerative disorder without satisfactory treatments nor a cure. It is caused by a CAG repeat expansion in the huntingtin gene. The clinical symptoms involve motor-, cognitive- and psychiatric disturbances. Recent studies have shown that...
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PMID: 20594177
PDF is available here.
Abstract
Direct blood pressure monitoring is the most accurate cardiovascular monitoring technique, but it is challenging in small mammals, as well as time-consuming and costly. Therefore, indirect blood pressure monitoring is most commonly used in clinic and laboratory settings. This column discusses indire...
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PMID: 20859277
PDF is available here.
Marie Moinet,
Christine Fournier-Chambrillon,
Geneviève André-Fontaine,
Stéphane Aulagnier,
Alain Mesplède,
Béatrice Blanchard,
Véronique Descarsin,
Philippe Dumas,
Yann Dumas,
Christophe Coïc,
Laurent Couzi and
Pascal Fournier
Abstract
We conducted a survey of antibody prevalence and renal carriage of pathogenic leptospira (Leptospira interrogans sensu lato) using serum and kidney samples collected from 1990 to 2007 from several free-ranging small carnivores and farmed American mink (Mustela vison) in southwestern France. An indir...
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PMID: 20966265
PDF is available here.
Abstract
A cross-sectional study into risk factors for Salmonella was undertaken using data gathered from 252 fattening turkey flocks in the UK. The data was derived from the EU baseline survey conducted during 2006 and 2007, in addition to a voluntary questionnaire. Multivariate logistic regression models i...
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PMID: 20163746
PDF is available here.
Abstract
We investigated helminth parasitism in 2 South American rodent species, Ctenomys australis and C. talarum (Octodontidae), to determine whether the unusual solitary and subterranean nature of these hosts would impact their patterns of infection. We applied generalized linear models to infection data...
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PMID: 20500917
PDF is available here.
Abstract
We present analysis of data on comparative chromosome painting produced using various chromosome-specific libraries for members of different Glires groups. Based on the results of comparative cytogenetic and molecular studies, the modern rodents can be conventionally classified into two groups with...
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PMID: 21061636
PDF is available here.
Abstract
I use two experiments on offshore islands in Cook Strait, New Zealand, to test the hypothesis that seabird restoration will restore island ecosystem functioning following invasive rodent removal. The first is a small-scale single-island fertilization experiment that simulates seabird recovery. This...
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PMID: 20666244
PDF is available here.
Abstract
Our study revealed that the B. tenagophila Taim isolate is susceptible to E. paraensei infection, although infection did not alter its resistance to S. mansoni infection....
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PMID: 20721499
PDF is available here.
Abstract
The protrogomorph condition of the rodent masticatory apparatus is thought to be present in only one living species, the mountain beaver Aplodontia rufa. The major anatomical difference between protrogomorphs and sciuromorphs is that the relative size of one part of the masseter muscle, the anterior...
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PMID: 20160427
PDF is available here.
Abstract
We isolated arenavirus RNA from white-toothed woodrats (Neotoma leucodon) captured in a region of Mexico in which woodrats are food for humans. Analyses of nucleotide and amino acid sequence data indicated that the woodrats were infected with a novel Tacaribe serocomplex virus, proposed name Real de...
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PMID: 20507759
PDF is available here.
Jônatas S Abrahão,
André T Silva-Fernandes,
Larissa S Lima,
Rafael K Campos,
Maria I M C Guedes,
Marcela M G Cota,
Felipe L Assis,
Iara A Borges,
Milton F Souza-Júnior,
Zélia I P Lobato,
Cláudio A Bonjardim,
Paulo C P Ferreira,
Giliane S Trindade and
Erna G Kroon
Abstract
We conducted a serosurvey of 344 wild animals. Neutralizing antibodies against orthopoxvirus were detected by plaque-reduction neutralizing tests in 84 serum samples. Amplicons from 6 monkey samples were sequenced. These amplicons identified vaccinia virus genetically similar to strains from bovine...
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PMID: 20507750
PDF is available here.
Abstract
We tested these predictions using extensive data on the faunas of fleas (Insecta: Siphonaptera) and gamasid mites (Acari: Parasitiformes) parasitic on rodents across the Palaearctic. For each pair of host species, we computed the similarity in parasite faunas based on both species composition as wel...
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PMID: 20036668
PDF is available here.
Abstract
Anoplocephalid cestodes have a worldwide distribution, but relatively few species are known from South American rodents. By examining the collections of the Harold W. Manter Laboratory of Parasitology and the United States National Parasite Collection, 6 new species of Monoecocestus Beddard, 1914, a...
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PMID: 20557205
PDF is available here.
Abstract
We will discuss findings that have revealed the role of designated populations of neurons for the key network functions including coordinating muscle activity and generating rhythmic activity. These findings are summarized in proposed organizational principles for the mammalian segmental CPG.
2010 E...
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PMID: 20494103
PDF is available here.
Abstract
Hepatitis E is a worldwide public health problem, especially in areas with poor sanitation. This study examines the potential hepatitis E virus (HEV) animal reservoirs and the current status of HEV infection among animals and humans in an endemic area of Xinjiang, China. One thousand...
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PMID: 20439982
PDF is available here.
Abstract
Rodents feed with and disperse plant seeds, which may thereby affect the seed spatiotemporal distribution, germination, and seedling establishment, and eventually play an important role in the restoration of deforested area. Taking the State-owned Yugong Forest Farm in Jiyuan of Henan, China as stud...
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PMID: 20707107
PDF is available here.
Takaaki Koma,
Kumiko Yoshimatsu,
Noemi Pini,
David Safronetz,
Midori Taruishi,
Silvana Levis,
Rika Endo,
Kenta Shimizu,
Shumpei P Yasuda,
Hideki Ebihara,
Heinz Feldmann,
Delia Enria and
Jiro Arikawa
Abstract
These results indicated that a screening ELISA using an E. coli-expressed antigen followed by a serotyping ELISA using trN100s is useful for epidemiological surveillance in regions where two or more hantavirus species cocirculate....
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PMID: 20335425
PDF is available here.
Abstract
We ask 1) whether we can replicate this result in rodents, 2) whether different autosomes replicate on average at different times, and 3) whether this might explain differences in their substitution rates. Finally we ask 4) whether X, Y, and autosome replicate at different times and 5) whether any d...
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PMID: 20026481
PDF is available here.
Abstract
OBJECTIVE: To critically evaluate the clinical evidence, and when not available, the animal data, most relevant to concerns that isoflavone exposure in the form of supplements or soy foods has feminizing effects on men. DESIGN: Medline literature review and cross-reference of published data. RESULT(...
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PMID: 20378106
PDF is available here.
Abstract
The spiny rat (Trinomys moojeni) is a rodent found in the Atlantic Forest, which is considered one of the most diverse and threatened biomes in the world. Knowledge on reproductive biology and physiology is critical to conservation and species management, allowing the prevention of extinction and th...
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PMID: 20018466
PDF is available here.
Abstract
Oscillatory fluctuations of local field potentials (LFPs) in the theta (4-8 Hz) and gamma (25-140 Hz) band are held to play a mechanistic role in various aspects of memory including the representation and off-line maintenance of events and sequences of events, the assessment of novelty, the inductio...
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PMID: 20181475
PDF is available here.
Abstract
The results show the need to increase the entomological surveillance in this region, given that the possibility of new cases of Chagas disease occurring through vector transmission was detected....
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PMID: 20464139
PDF is available here.
Stephen D Goble,
Liping Wang,
K Lulu Howell,
Alka Bansal,
Richard Berger,
Linda Brockunier,
Jerry DiSalvo,
Scott Feighner,
Bart Harper,
Jiafang He,
Amanda Hurley,
Donna Hreniuk,
Emma Parmee,
Michael Robbins,
Gino Salituro,
Anthony Sanfiz,
Eric Streckfuss,
Eloisa Watkins,
Ann E Weber,
Mary Struthers and
Scott D Edmondson
Abstract
A series of amide derived beta(3)-adrenergic receptor (AR) agonists is described. The discovery and optimization of several series of compounds derived from 1, is used to lay the SAR foundation for second generation beta(3)-AR agonists for the treatment of overactive bladder.
Copyright 2010 Elsevier...
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PMID: 20181479
PDF is available here.
Abstract
Spermatogonial stem cells (SSCs) maintain spermatogenesis throughout the reproductive life of mammals. While A(single) spermatogonia comprise the rodent SSC pool, the identity of the stem cell pool in the primate spermatogenic lineage is not well established. The prevailing model is that primate spe...
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PMID: 19880674
PDF is available here.
Abstract
Calcium signaling plays a key role in bone turnover, regulating both osteoblasts and osteoclasts. Despite this the role of calmodulin, the primary intracellular calcium receptor regulatory protein, has received little attention. In this brief review, the function of Ca(2+)/calmodulin signaling in os...
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PMID: 20392260
PDF is available here.
Abstract
The work attempts to explain the previously discovered phenomenon of excessive taxonomic status of the species and subspecies of Cuban hutias relative to their protein genetic divergence. The reasons underlying the fragmentary distribution of the species belonging to the family Capromyidae over the...
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PMID: 20297656
PDF is available here.
Abstract
We summarize and discuss our recent findings on a four domain cation channel named NALCN which has been previously described as mediating a TTX-resistant leak sodium current in neurons. We recently reported that NALCN is also expressed in rodent islets of Langerhans as well as in the mouse MIN6 panc...
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PMID: 21099296
PDF is available here.
Abstract
We also wish to point out the irrelevance of the adjective dermotropic or viscerotropic to qualify L. braziliensis and L. infantum, respectively, when these species are hosted by nonhuman hosts. Our data suggest that T. laurentius may act at least as a maintenance host of both tested Leishmania spec...
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PMID: 20126407
PDF is available here.
Abstract
Fibroblast growth factor 21 (FGF21) is an atypical member of the FGF family that functions as an endocrine hormone. Pharmacologic studies show that FGF21 has broad metabolic actions in obese rodents and primates that include enhancing insulin sensitivity, decreasing triglyceride concentrations, and c...
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PMID: 19906798
PDF is available here.
Abstract
We detected in these chromocenters the typical highly repeated DNA of this genus after in situ hybridization, the M31 chromodomain through immunofluorescence as well as dense Giemsa staining after C-banding. In species that present low amounts of heterochromatin, only 1 or 2 chromocenters were obser...
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PMID: 20389031
PDF is available here.
Abstract
Folliculostellate cells (FSC) have been reported in pituitary of several mammalian species. FSC morphology and secreted substances have been instrumental to the understanding of their function. The purpose of this work was to perform an immunohistochemical, morphometric and ultrastructural study of...
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PMID: 20353904
PDF is available here.
Abstract
We investigated the role of endogenously-produced versus exogenously-administered melatonin in a major thermal injury rat model with well-characterized gut inflammatory complications. Our rationale is that understanding in vivo melatonin mechanisms in control and inflamed tissues will improve our un...
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PMID: 20567497
PDF is available here.
Abstract
Explanations for the dynamics of tick-borne disease systems usually focus on changes in the transmission potential in natural enzootic cycles. These are undoubtedly important, but recent analyses reveal that they may not be quantitatively the most significant side of the interaction between infected...
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PMID: 20630144
PDF is available here.
Abstract
The two-year rodent bioassay remains the mainstay for carcinogenicity testing, although numerous difficulties have been identified. Fundamentally, a chemical can increase the risk of cancer (1) by damaging DNA directly (DNA reactive) or (2) indirectly by increasing the number of DNA replications (no...
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PMID: 20215581
PDF is available here.
Abstract
Distribution of fleas by their rodents hosts was investigated by field experiments using the method of individual labeling both the parasites and the hosts. The experimental site was situated in sand landscapes of the northwestern Precaspian region. Pattern of the contacts between rodents leading to...
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PMID: 20349635
PDF is available here.
Abstract
Schistosoma japonicum remains highly endemic in many counties in China and has recently re-emerged, to a large extent, in previously controlled areas. To test the hypothesis that small rodents and less agriculturally important domestic animals such as dogs and cats may play an important role in the...
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PMID: 19723358
PDF is available here.
Abstract
The karyotypes of the lesser Egyptian jerboa Jaculus jaculus and the greater Egyptian jerboa Jaculus orientalis from Tunisia are described and compared with available data particularly from Egypt. The species examined have a similar karyotype consisting of 2n = 48 chromosomes and a fundamental numbe...
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PMID: 20968190
PDF is available here.
Abstract
We report a case of severe leptospirosis infection (Weil's disease) in Tokyo. A 54-year-old man admitted on September 14, 2006, for a 5-day inability to walk due to severe progressive bilateral leg pain, shoulder pain, and fever exhibited jaundice, conjunctival suffusion, hypoxia, and grasping pain...
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PMID: 20170016
PDF is available here.
Abstract
We review technical aspects of both in utero and exo utero surgical approaches and how these surgeries are used in conjunction with other experimental applications.
Copyright (c) 2010 Elsevier Inc. All rights reserved....
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PMID: 20691868
PDF is available here.
Abstract
We intracerebrally inoculated four species of epidemic-sympatric rodents with CWD. Transmission was efficient in all species; the onset of disease was faster in the two vole species than the two Peromyscus spp. The results for inocula prepared from CWD-positive deer with or without CWD-resistant gen...
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PMID: 19828611
PDF is available here.