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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Mycobacterium (8):
Recent article
Mycobacterium
Abstract
The aim of tuberculosis treatment is to cure the individual patient with antituberculosis drugs (ATT) in a short time without emergence of drug resistance. The anti tuberculosis drugs are selected in a combination to attack all the subpopulations of tubercle bacilli with first line drugs which includ...
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PMID: 21049292
PDF is available here.
PDF is available here.
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Abstract
I (4, 3.08%), LAM (2, 1.54%), X (N = 1, 0.77%) and S (2, 1.54%). Nine isolates had SIT numbers with no identified sub-lineages while 17 had no SIT numbers. MTBss isolates were more likely to be resistant to streptomycin (p<0.008) and to any drug resistance (p<0.03) when compared to M. africanum....
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PMID: 21779354
PDF is available here.
PDF is available here.
Abstract
We tested the effect of innate immune interactions between human DC and M. vaccae on DC-dependent T cell responses. M. vaccae activation of DC via Toll like receptor (TLR)2 was compared to a specific TLR2 ligand (Pam(3)CSK4) and alternative stimulation with a TLR4 ligand (LPS). M. vaccae induced DC...
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PMID: 21483768
PDF is available here.
PDF is available here.
Molecular characteristics of "Mycobacterium canettii" the smooth Mycobacterium tuberculosis bacilli.
Abstract
We have collected 59 SmTB isolates of which 14 were newly recovered since previous reports, and performed extensive phenotypical and genotypical characterization. We take advantage of these investigations to review the current knowledge of "M. canettii". Their characteristics and the apparent lack o...
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PMID: 20692377
PDF is available here.
PDF is available here.
Abstract
Two approaches are presented for the synthesis of the macrolide core of the mycolactone polyketides. The first intertwines ring closing metathesis (RCM) within a two-step Julia olefination protocol, while the second intercepts the optimized routes of Kishi, thereby providing formal access to the myc...
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PMID: 20844795
PDF is available here.
PDF is available here.
Emerging Infectious Diseases (16)10 2010
Abstract
We compared isolates obtained in 1999 and 2005 and used data from the Queensland notification scheme to report the clinical relevance of these isolates. The incidence of notified cases of clinically significant pulmonary disease rose from 2.2 (1999) to 3.2 (2005) per 100,000 population. The pattern...
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PMID: 20875283
PDF is available here.
PDF is available here.
Abstract
We propose the previously deposited reference strain ATCC 12670(T) =DSM 44181(T) =NCIMB 10420(T), located in collections worldwide, as the type strain....
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PMID: 19915104
PDF is available here.
PDF is available here.
Biotechnology Letters (32)10 2010
Abstract
3-Hexulose-6-phosphate synthase (HPS) and 6-phosphate-3-hexuloisomerase (PHI) are two key enzymes in the formaldehyde (HCHO) assimilation pathway in methylotrophs. The HPS/PHI fusion protein, encoded by the chimeric gene of hps and phi from Mycobacterium gastri MB19, possesses both HPS and PHI activ...
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PMID: 20549541
PDF is available here.
PDF is available here.
Abstract
Our results indicate that PCR amplification and sequencing of the mycobacterial hsp65 gene is a sensitive assay for identification of NTM species in FFPE materials. However, consistent results of PCR analysis, microbiology study, histologic manifestations, radiology, and clinical presentation are im...
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PMID: 20850247
PDF is available here.
PDF is available here.
Kidney International (78)10 2010
Abstract
Abstract
We briefly review evidence that mycobacterial antigens are involved in sarcoidosis pathogenesis, and explore how defects in innate immunity might contribute to the disease.
Patients with sarcoidosis demonstrate antigen-specific immune responses against mycobacterial virulence factors systemically an...
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PMID: 20473167
PDF is available here.
PDF is available here.
Abstract
Mycobacterium spp. infection is an important health concern for Asian elephant (Elephas maximus) populations worldwide. The disease is of particular concern considering its potential to affect not only the individual animal but also herd and public health. Although elephant tuberculosis susceptibili...
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PMID: 20945642
PDF is available here.
PDF is available here.
Journal of Medical Microbiology (59)Pt 8 2010
Abstract
We report six recent pulmonary cases caused by M. microti over a period of 5 years detected in French clinical mycobacteriology laboratories of the hospital network. Our data confirm the potential of M. microti to cause clinical illness in immunocompetent patients. M. microti grew slowly from specim...
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PMID: 20488936
PDF is available here.
PDF is available here.
Abstract
All cases were followed up from 1 to 5 years with an average of 3.1 years. Recurrence was found in 2 cases who were cured after second operation. 34 cases with neurological deficits recovered totally or partially. X-ray or CT films showed spinal fusion in 57 patients. CONCLUSION:The therapeutic effe...
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PMID: 20701116
PDF is available here.
PDF is available here.
Abstract
All 232 cases recovered from perioperation and 230 cases got primary wound healing, only 2 cases performed with single incision one-stage posterior instrumentation and anterolateral debridement got complications of wound healing problems and the sinus formation,which delayed healed by changing dress...
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PMID: 20701117
PDF is available here.
PDF is available here.
Abstract
Abstract
Arthritis & Rheumatism (62)7 2010
Abstract
Arthritic rats treated with MG132 demonstrated a marked reduction in inflammation, pain, and joint destruction. The elevated DNA-binding activity of the NF-kappaB/p50 homodimer and p50, as well as the neuronal expression of SP and CGRP, observed in the ankle joints of arthritic rats were normalized...
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PMID: 20506183
PDF is available here.
PDF is available here.
Abstract
Nontuberculous mycobacteria (NTM) are environmental opportunistic pathogens of humans and animals. They are found in a wide variety of habitats to which humans are exposed, including drinking water distribution systems and household water and plumbing. In that regard, they are distinct from their ob...
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PMID: 20521938
PDF is available here.
PDF is available here.
Abstract
Our aim is to investigate if the clusters of postsurgical mycobacterial infections, reported between 2004 and 2008 in seven geographically distant states in Brazil, were caused by a single mycobacterial strain.
Available information from 929 surgical patients was obtained from local health authoriti...
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PMID: 20521940
PDF is available here.
PDF is available here.
Abstract
We review some of the mechanisms by which mycobacterial infection might modulate the clinical course of CNS autoimmunity. A more complete understanding of these mechanisms may lead to the development of novel immunotherapeutic tools for treating autoimmune diseases....
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PMID: 20333556
PDF is available here.
PDF is available here.
Abstract
Ergothioneine is a histidine-derived thiol of bacterial and fungal origin that has also been isolated from animal and human tissue. Recent findings point to critical functions of ergothioneine in human physiology, but its role in microbial life is poorly understood. This report describes the identif...
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PMID: 20420449
PDF is available here.
PDF is available here.
Abstract
We report a case of M abscessus with review of the literature, which revealed 1 confirmed case in an HIV/AIDS patient. Preliminary diagnosis was presumed to be pulmonary tuberculosis secondary to positive acid-fast bacilli in sputum stain. After initial treatment failure, sputum stains were repeated...
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PMID: 20375687
PDF is available here.
PDF is available here.
Abstract
Thirty-five NTM patients and 140 tuberculosis (TB) patients were reviewed. Patients with NTM pleurisy were less likely to have lung involvement and receive anti-mycobacterial treatment compared with those with tuberculous pleurisy. NTM pleurisy had a higher PE leukocyte count and a lower percentage...
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PMID: 20392359
PDF is available here.
PDF is available here.
Abstract
We looked for non-tuberculous mycobacteria (NTM) in the sputum of patients diagnosed with pulmonary tuberculosis (TB) in Oregon in 2005-2006 (n = 141). Twenty (14%) patients had NTM isolated from sputum during TB treatment. Compared to those without NTM, TB patients with NTM were more likely to have...
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PMID: 20392362
PDF is available here.
PDF is available here.
Microbiology (156)Pt 5 2010
Abstract
We described a TetR-type transcriptional repressor, kstR, that controls the expression of a number of genes involved in cholesterol catabolism. In this study, we describe a second TetR-type repressor, which we call kstR2. We knocked this gene out in Mycobacterium smegmatis and used microarrays and q...
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PMID: 20167624
PDF is available here.
PDF is available here.
Microbiology (156)Pt 5 2010
Abstract
We report here the search for and transcription analysis of this set of genes in the genus Mycobacterium. An in silico search for cellulose-targeting orthologues found that only 2.5 % of the sequenced bacterial genomes encode the Cel6, Cel12 and CBD2 gene set simultaneously, including those of the M...
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PMID: 20150238
PDF is available here.
PDF is available here.
Abstract
We propose a nitrate reduction test coupled to Bactec MGIT960 system as a simple, rapid and economic method with a total gain of time of about 3 to 4weeks over the conventional solid medium. In our study, almost all the M. tuberculosis and Mycobacterium canettii strains gave a strongly positive nitr...
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PMID: 20298726
PDF is available here.
PDF is available here.
Abstract
After three weeks of culture, smooth and non-photochromogenic colonies were formed. The niacin accumulation test was negative. The homologies of DNA sequence between the new strains and M. tuberculosis for 16S rRNA and rpoB genes were 97.8% and 90.2%, respectively. The tests with TRC and MTD kits we...
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PMID: 20560401
PDF is available here.
PDF is available here.
Journal of Infection (60)5 2010
Abstract
Available evidence shows that MV is effective in preventing TB in PPD strong positive/type 2 diabetes mellitus/aged people of clinical cured pulmonary TB, and is safe, well-tolerated and effective in inducing biologically relevant immune response against TB in HIV-infected patients. High-quality tri...
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PMID: 20156481
PDF is available here.
PDF is available here.
Abstract
A 1-year-old, entire male Tasmanian devil living in captivity was presented because of a nodular inguinal lesion that subsequently developed a draining sinus tract. A second, similar lesion developed later in the ipsilateral axillary region. A deep representative biopsy specimen of abnormal subcutan...
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PMID: 20529031
PDF is available here.
PDF is available here.
Abstract
The microbial adhesion to hydrocarbons (MATH) assay has been used widely to characterize microbial cell hydrophobicity and/or the extent of cell adhesion to hydrophobic liquids. The classical MATH assay involves spectrophotometric absorbance measurements of the initial and final cell concentrations...
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PMID: 20129613
PDF is available here.
PDF is available here.
Abstract
Extraction of genomic DNA from mycobacteria requires special consideration because (i) many mycobacterial species exhibit extremely slow growth, and thus produce only small amounts of starting material, and (ii) a robust and waxy cell wall renders mycobacteria difficult to lyse. Hence, mycobacterial...
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PMID: 20360362
PDF is available here.
PDF is available here.
Microbiology (156)Pt 4 2010
Abstract
Carbon monoxide dehydrogenase (CO-DH) is an enzyme catalysing the oxidation of CO to carbon dioxide in Mycobacterium sp. strain JC1 DSM 3803. Cloning of the genes encoding CO-DH from the bacterium and sequencing of overlapping clones revealed the presence of duplicated sets of genes for three subuni...
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PMID: 20035005
PDF is available here.
PDF is available here.
Abstract
Frequent "contaminants" detected during mycobacterial culture of decontaminated samples are bacteria of the order Actinomycetales. These are usually bacteria classified as the family Corynebacterineae, genera Corynebacterium, Dietzia, Gordonia, Nocardia, Rhodococcus and Tsukamurella. These bacteria...
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PMID: 20503156
PDF is available here.
PDF is available here.
Abstract
Nontuberculous mycobacterial lung disease associated radiographically with nodules and bronchiectasis occurs primarily in women. These patients are associated with a specific morphotype, including low BMI, tall stature, scoliosis, pectus excavatum and mitral valve prolapse. The pathophysiologic link...
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PMID: 20087178
PDF is available here.
PDF is available here.
Journal of Biochemistry (147)4 2010
Abstract
The gene encoding a catalase-peroxidase (KatG) was cloned from chromosomal DNA of a fast-growing Mycobacterium sp. strain JC1 DSM 3803. The nucleotide sequence of a 5.7 kb EcoRI fragment containing the katG and its flanking regions was determined. The fragment (5,706 bps) contained two complete open...
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PMID: 19933836
PDF is available here.
PDF is available here.
Abstract
Analysis of the transcriptional profiles of Mycobacterium tuberculosis after treatment with antimycobacterial compounds has improved our understanding of the ways mycobacteria respond to antibiotic stress, and revealed new insights into the mode of action of different antimycobacterial compound clas...
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PMID: 20401587
PDF is available here.
PDF is available here.
Abstract
Legionella and Mycobacterium can proliferate within free-living amoebae (FLA) where they are protected from disinfectants at concentrations that can kill bacteria but not protozoa. Despite effective treatment of drinking water, microbes can enter water utility distribution systems (DS) and hence the...
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PMID: 20009249
PDF is available here.
PDF is available here.
Abstract
Tuberculosis (TB) is caused by pathogenic species within the Mycobacterium tuberculosis complex (MTBC). In the present case, a 40-year-old African man was admitted acutely. Despite negative microscopy, anti-TB treatment was initialized. Thirteen hours after hospitalisation, the patie...
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PMID: 20156408
PDF is available here.
PDF is available here.
Abstract
We estimate here whether being undocumented is a determinant of TB, independently of origin. Cross-sectional study including undocumented migrants in a TB screening program in 2002; results were compared to 12,904 age and frequency matched participants in a general TB screening program conducted at...
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PMID: 19582582
PDF is available here.
PDF is available here.
Abstract
Revista Medica de Chile (138)2 2010
Abstract
We report two patients with perianal tuberculosis. An 82-year-old male presenting with purulent perianal discharge and weight loss. A pelvic magnetic resonance imaging showed a low trans sphincteric anorectal fistula with abscess formation. A fistulectomy was performed and the pathological study sho...
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PMID: 20461312
PDF is available here.
PDF is available here.
Abstract
We performed in vitro susceptibility testing by Etest of four carbapenems for M. abscessus isolates. Imipenem demonstrated the most in vitro activity, and testing of other carbapenems provided no additional value....
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PMID: 20018813
PDF is available here.
PDF is available here.
Chinese Medical Journal (123)2 2010
Abstract
The prevalence of NTM in Shanghai showed a tendency to increase over the course of the study. The five most commonly isolated NTM species showed high drug resistance to first line anti-tuberculosis drugs....
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PMID: 20137367
PDF is available here.
PDF is available here.
Abstract
We report that the genomes of Mycobacterium species and those of other high G+C Gram-positive bacteria lack orthologs of many, if not all, highly conserved genes diagnostic of endospore formation in the genomes of low G+C Gram-positive bacteria. We also failed to detect the presence of endospores by...
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PMID: 20080769
PDF is available here.
PDF is available here.
Abstract
Abstract
I cases.
EPTB accounts for 10-15 percent of all cases of tuberculosis. Mycobacterium was present in 10.5 percent samples. 48 isolates out of 54 samples were found to be M. tuberculosis. The maximum numbers of M. tuberculosis were isolated from lymph node aspiration....
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PMID: 21209509
PDF is available here.
PDF is available here.
Euro surveillance : bulletin europeen sur les maladies transmissibles = European communicable disease bulletin (15)11 2010
Abstract
Abstract
We aim to describe a method in this chapter performed in a six-well plate format. This method can also be extended accurately to a 96-well plate format according to the necessity of the project. In addition to evaluating a range of prospective drug candidates, this method would also contribute to el...
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PMID: 20401596
PDF is available here.
PDF is available here.
Abstract
In this study, a series of fourteen ring-substituted 8-hydroxyquinoline derivatives were prepared. The synthesis procedures are presented. The compounds were analyzed using RP-HPLC to determine lipophilicity. They were tested for their activity related to inhibition of photosynthetic electron transp...
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PMID: 20110891
PDF is available here.
PDF is available here.
Abstract
Seeding of 117,579 samples of clinical materials at the Central Microbiological Laboratory, Moscow Research and Practical Centre of Tuberculosis, resulted in isolation of 15,786 (13,4%) mycobacterial cultures, with 15,333 (97.1%) ones being identified as M. tuberculosis complex and 490 (3.1%) as non...
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PMID: 20420209
PDF is available here.
PDF is available here.
Khirurgiia ()6 2010
Abstract
We present a case operated from us in Multi Pro File Hospital Cherven Bryag. A 54 years old male patient with peritonitis due to perforated intestinal TB and upper intestinal fistulas. The patient was not aware of suffering from pulmonary TB in the past....
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PMID: 21972722
PDF is available here.
PDF is available here.
Abstract
A search for C(35)-terpenes from non-saponified extracts of 12 non-pathogenic Mycobacterium species was carried out. Octahydroheptaprenyl mycolic acyl esters were isolated from M. chlorophenolicum cells which were also found from M. thermoresistibile, M. vanbaalenii, M. aichiense, M. smegmatis, and...
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PMID: 20057120
PDF is available here.
PDF is available here.
Abstract
Abstract
Abstract
We analyzed, with INNO LiPA MYCOBACTERIA (Innogenetics) and with GenoType Mycobacterium (Hein), 317 strains, belonging to 136 species, 61 of which had never been assayed before. INNO LiPA misidentified 20 taxa, the majority of which cross-reacted with the probes specific for Mycobacterium fortuitum...
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PMID: 19906898
PDF is available here.
PDF is available here.
Abstract
To prevent transmission of mycobacterial pathogens, medical devices must be disinfected by germicides with proven mycobactericidal activity. The quantitative carrier test EN 14563 provides an international standard for evaluation of the mycobactericidal activity of disinfectants under practical cond...
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PMID: 19948860
PDF is available here.
PDF is available here.
Abstract
Mycobacterium asiaticum was first reported as a cause of human disease in 1982, with only a few cases in the literature to date. This study aims to review the clinical significance of M. asiaticum isolates in Queensland, Australia. A retrospective review (1989 to 2008) of patients with M. asiaticum...
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PMID: 19864478
PDF is available here.
PDF is available here.
Abstract
A multiplex method using the SNaPshot technique was developed to screen for six common mycobacterial species: Mycobacteria tuberculosis, M. avium, M. intracellulare, M. chelonae, M. kansasii, and M. gordonae. A total of 468 mycobacterial clinical isolates were subjected to analysis for the presence...
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PMID: 19889900
PDF is available here.
PDF is available here.