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Gram-Positive Bacteria (4):
Recent article
Gram-Positive Bacteria
Abstract
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Abstract
We show that RegIIIγ, a secreted antibacterial lectin, is essential for maintaining a ~50-micrometer zone that physically separates the microbiota from the small intestinal epithelial surface. Loss of host-bacterial segregation in RegIIIγ(-/-) mice was coupled to increased bacterial colonization o...
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PMID: 21998396
PDF is available here.
PDF is available here.
Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti (60)2 2011
Abstract
Lactic acid bacteria comprise several genera of gram-positive bacteria that are known for the production of structurally different antimicrobial substances. Among them, bacteriocins are nowadays in the centre of scientific interest. Bacteriocins, proteinaceous antimicrobial substances, are produced r...
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PMID: 21650008
PDF is available here.
PDF is available here.
Natural Product Reports (27)11 2010
Abstract
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences (35)11 2010
[Distribution and antibiotic resistance of pathogen isolated from mid-stream urine of 658 patients].
Abstract
To investigate the bacterial distribution and resistance to antibiotics in culture-positive urine, and to provide reference for rational use of antibiotics in clinical practice.
Distribution and antibiotic resistance to pathogens in 658 culture-positive patients from...
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PMID: 21131743
PDF is available here.
PDF is available here.
Abstract
We report the current knowledge about the sRNAs of these socioeconomically relevant Gram-positive pathogens, overview the state-of-the-art high-throughput sRNA screening methods and summarize bioinformatics approaches for genome-wide sRNA identification and target prediction. Finally, we discuss the...
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PMID: 21255362
PDF is available here.
PDF is available here.
EMBO Journal (29)21 2010
Abstract
We provide evidence that CtsR activity during heat stress is mediated by intrinsic heat sensing through a glycine-rich loop, probably in all Gram-positive species. Moreover, a function for the recently identified arginine kinase McsB is confirmed, however, not for initial inactivation and dissociati...
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PMID: 20852588
PDF is available here.
PDF is available here.
Journal of Antibiotics (63)11 2010
Abstract
Abstract
These results demonstrate that cell wall from MTV can be used to differentially bind E. coli spp. and Salmonella spp. up to 8×10(4) CFU/10 μg. Thus certain yeast cell walls may prevent enteric infections caused by selective bacteria. This methodical approach would be an accurate tool in the feed i...
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PMID: 20826190
PDF is available here.
PDF is available here.
Abstract
Defined as proteins actively transported via secretion systems, secreted proteins can have radically different subcellular destinations in monoderm (Gram-positive) bacteria. From degradative enzymes in saprophytes to virulence factors in pathogens, secreted proteins are the main tool...
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PMID: 20839850
PDF is available here.
PDF is available here.
Abstract
We expressed and purified the modified BhSGAMP-1-S and investigated its antimicrobial activity.
We synthesized the gene of BhSGAMP-1-S designed with preferred codons of Escherichia coli and expressed it as a fusion protein in E. coli TB1 by using pMAL-c2X as vector. We purified the fusion protein us...
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PMID: 21090174
PDF is available here.
PDF is available here.
Abstract
A series of novel 6-O-substituted 8a-aza-8a-homoerythromycin A ketolides was synthesized and evaluated for in vitro antibacterial activity. Key strategic elements of the synthesis include the base-induced E-Z isomerization of 3-O-descladinosyl-6-O-allylerythromycin A 9(E)-oxime followed by ring-expa...
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PMID: 20684614
PDF is available here.
PDF is available here.
Abstract
Of the 60 patients, 88.3% had monomicrobial infection and 11.7% had mixed infection. The mean duration from the first neurosurgical procedure to the diagnosis of meningitis was 21 days (range, 1-134 days). The median frequency of neurosurgical procedure before meningitis was 1 (range, 1-5). A total...
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PMID: 20688290
PDF is available here.
PDF is available here.
Metallomics (2)8 2010
Abstract
We describe the silver(i) complex of this important biological molecule and show that the binding mode is through the phenoxazine ring nitrogen. A new synthetic route to 2-aminophenoxazine-3-one is also reported....
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PMID: 21072337
PDF is available here.
PDF is available here.
Abstract
Although many antimicrobial components (i.e. antimicrobial peptides) have been found in many social Hymenoptera venoms, no antimicrobial compound is purified and characterized from parasitic Hymenoptera. From the venoms of the ectoparasitic wasp, Nasonia vitripennis, a defensin-like antimicrobial pe...
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PMID: 20362606
PDF is available here.
PDF is available here.
Hematology (15)4 2010
Abstract
Pathogens were isolated from 44% of all patients. MM patients more frequently had multiple pathogens in blood cultures (38% versus 25%). Transplantation related mortality was similar between the groups. CONCLUSION: The frequency of isolated pathogens, positive blood cultures, and the diversity of pa...
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PMID: 20670481
PDF is available here.
PDF is available here.
Abstract
These results suggest that enzymatic deproteinization of the shrimp shell wastes, using B. cereus SV1 protease, could be applicable to the chitin production process....
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PMID: 19960271
PDF is available here.
PDF is available here.
Abstract
BACKGROUND AND OBJECTIVIES: Nepeta species are used as diuretic, diaphoretic, antitussive, antispasmodic, antiasthmatic, febrifuge, emmenagogue, sedative agents, insecticidal, acaricidal, antiviral, anti-inflammatory and antioxidant. Acetone extract of Nepeta meyeri (Labiatae) was screened for antio...
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PMID: 20707285
PDF is available here.
PDF is available here.
Journal of Bacteriology (192)15 2010
Abstract
FEMS Microbiology Letters (309)1 2010
Abstract
A mesophilic, syntrophic acetate-oxidizing bacterium, designated strain Sp3(T), was isolated from sludge from a mesophilic methanogenic digestor operating at a high ammonium concentration (6.4 g L(-1) NH(4)(+)-N). The strain showed acetate-oxidizing ability in cocultivation with a hy...
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PMID: 20546311
PDF is available here.
PDF is available here.
Abstract
Different disinfecting solutions used during storage in cases result in different levels of contamination and contamination by different types of microbes. These differences are not simply because of the types of disinfectants used, suggesting that other excipients in, or formulation of, the solutio...
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PMID: 20436374
PDF is available here.
PDF is available here.
Abstract
Antibiotic resistance development is an ongoing process associated with irrational antibiotic use. WHO recommends regular surveillance programs for monitoring of antibiotic resistance. The present study is a step in this direction. A total of 124 clinical isolates of Escherichia coli, Staphylococcus...
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PMID: 20566434
PDF is available here.
PDF is available here.
Abstract
We report the biosynthesis of extracellular silver-based single nanocrystallites of well-defined composition and homogeneous morphology utilizing the gamma-proteobacterium, Shewanella oneidensis MR-1, upon incubation with aqueous silver nitrate solution. Further characterization of these particles r...
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PMID: 20509652
PDF is available here.
PDF is available here.
Abstract
Although Gram-negative bacteria are the most common etiology of fever in neutropenic patients, the occurrence of infections caused by coagulase-negative Staphylococcus and molds has been increasing in comparison with the observations from previous studies in King Chulalongkorn Memorial Hospital. To...
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PMID: 20649055
PDF is available here.
PDF is available here.
Abstract
I crustins were both identified in CrusEs, suggesting that CrusEs is a new member of type I crustins. Quantitative real-time RT-PCR was employed to examine the expression of CrusEs, and its mRNA transcript was mainly detected in haemocytes and gill. The CrusEs mRNA transcript in haemocytes was down-...
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PMID: 20144896
PDF is available here.
PDF is available here.
Pharmaceutical Biology (48)7 2010
Abstract
The epicarp and seed of Persea Americana Mill. var. Hass (Lauraceae), Persea Americana Mill. var. Shepard, and Persea americana Mill. var Fuerte cultivars of mature avocados (n = 3) were ground separately and extracted with both absolute ethanol and distilled water. Extracts were analyzed for antimi...
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PMID: 20645772
PDF is available here.
PDF is available here.
Abstract
Halogen derivatives of selected 3-benzofurancarboxylic acids were prepared using 6-acetyl-5-hydroxy-2-methyl-3-benzofuranocarboxylic acid as starting material. (1)H-NMR spectra were obtained for all of the synthesized structures, and for compound VI, an X-ray crystal structure was also obtained. All...
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PMID: 20657389
PDF is available here.
PDF is available here.
Abstract
We have investigated the antibacterial activity of some new steroidal thiosemicarbazones and their Pd(II) metal complexes were prepared by the reaction of the thiosemicarbazones with [Pd(DMSO)(2)Cl(2)]. The steroidal thiosemicarbazones were prepared by the reaction of thiosemicarbazides with a stero...
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PMID: 20657393
PDF is available here.
PDF is available here.
FEMS Microbiology Letters (308)1 2010
Abstract
Rainbow trout gastroenteritis has been related to the accumulation of segmented filamentous bacteria in the digestive tract of fish, which presents lethargy, reduced appetite and accumulation of mucoid faeces. Some authors associate the comparison of illness with the presence of viable filaments, wh...
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PMID: 20455950
PDF is available here.
PDF is available here.
Abstract
Gram-positive bacteria have developed elaborate mechanisms to control ammonium assimilation, at the levels of both transcription and enzyme activity. In this review, the common and specific mechanisms of nitrogen assimilation and regulation in Gram-positive bacteria are summarized an...
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PMID: 20337720
PDF is available here.
PDF is available here.
Abstract
The study of biochemical activity of extracts obtained from marine organisms is gaining interest as some have proved to have efficient health or industrial applications. To evaluate lethality and antimicrobial activities, some chemical tests were performed on crude extracts of the octocorals Eunicea...
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PMID: 20527468
PDF is available here.
PDF is available here.
Abstract
These results extend the list of promising isothioureas with substantial activity in vitro and suggest that an in-depth study of toxicity, antimicrobial properties in vivo and nitric oxide synthase isoform selectivity of selected novel compounds is warranted....
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PMID: 20607486
PDF is available here.
PDF is available here.
Abstract
A prevalence study aimed to update the epidemiological scenario of Hospital-Acquired Infections (HAI) was performed at the San Martino University Hospital of Genoa, the Regional Reference Adult-care Center in Liguria, Italy, with more than 1300 beds.
The investigation was performed in all the wards,...
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PMID: 21155410
PDF is available here.
PDF is available here.
Abstract
A quadruplex real-time (RT) qPCR assay for the detection and quantification in 4h of Staphylococcusaureus, Pseudomonasaeruginosa, Acinetobacterbaumannii and Stenotrophomonasmaltophilia directly from bronchoalveolar lavage specimens was developed. The specificity of the assay was 100% for all four sp...
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PMID: 20353803
PDF is available here.
PDF is available here.
Current Protocols in Toxicology (Chapter 21) 2010
Abstract
The disruption of intestinal barrier leads to the penetration of noxious luminal compounds into the gut wall, causing further damage. This unit describes the assessment of enteric bacteria translocation into the intestinal wall of rats, an established method for the evaluation of bow...
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PMID: 20967745
PDF is available here.
PDF is available here.
Abstract
The bacteria cell envelope is a complex multilayered structure that serves to protect these organisms from their unpredictable and often hostile environment. The cell envelopes of most bacteria fall into one of two major groups. Gram-negative bacteria are surrounded by a thin peptidoglycan cell wall,...
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PMID: 20452953
PDF is available here.
PDF is available here.
Abstract
A cellulolytic and xylanolytic enzyme complex-producing alkalothermoanaerobacterium strain, Tepidimicrobium xylanilyticum BT14 is described. The cell was Gram-positive, rod-shaped and endospore-forming. Based on 16S rRNA gene analysis and various lines of biochemical and physiological properties, th...
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PMID: 20519913
PDF is available here.
PDF is available here.
Abstract
We use a library of peptide derivatives to demonstrate that the antimicrobial activity can be localized to a particular region. Overlapping fragments of the N-terminal region were tested for their ability to kill Gram-positive and Gram-negative bacteria. We demonstrate that the most N-terminal fragm...
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PMID: 20176896
PDF is available here.
PDF is available here.
Abstract
This study assessed the spectrum of activity of torezolid (TR-700), the active moiety of torezolid phosphate (TR-701), and proposes tentative MIC and disk diffusion breakpoints as well as quality control ranges. The in vitro susceptibilities of 1,096 bacterial isolates, representing 23 different spe...
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PMID: 20231392
PDF is available here.
PDF is available here.
Abstract
The in vitro activity of CEM-101, a new fluoroketolide, was determined against Gram-positive organisms with various macrolide susceptibility profiles. Experiments for determination of the MICs and minimum bactericidal concentrations (MBCs), timed killing, single-step and multistep mutation rates, th...
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PMID: 20176910
PDF is available here.
PDF is available here.
Trends in Microbiology (18)5 2010
Abstract
We focus on recent advances in one of the longest-studied Gram-negative pilus systems, the chaperone/usher assembled pili, along with the newcomer to the field, the sortase-assembled pili of Gram-positive bacteria. In both systems, a wealth of new structural and molecular details has emerged recentl...
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PMID: 20378353
PDF is available here.
PDF is available here.
Abstract
We tested different plant extracts, their mixtures and phenolic acids on selected gram-positive (Staphylococcus aureus, Bacillus cereus, and Listeria monocytogenes) and gram-negative bacteria (Escherichia coli O157:H7, Salmonella Infantis, Campylobacter jejuni, Campylobacter coli) with the disk diff...
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PMID: 20171250
PDF is available here.
PDF is available here.
Journal of Ethnopharmacology (128)3 2010
Abstract
The tested microbes Micrococcus flavus and Escherichia coli were highly susceptible to extract CE and antimicrobial activity of CB is comparable to that of extract CE against Escherichia coli and Staphylococcus faecalis while it is better than that of extract CE, against Klebsiella pneumoniae. Both...
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PMID: 20176098
PDF is available here.
PDF is available here.
Journal of Ethnopharmacology (128)3 2010
Abstract
A new bioactive compound was isolated and identified as a cassane diterpene, niloticane. Niloticane showed antibacterial activity against Gram-positive bacteria Bacillus subtilis and Staphylococcus aureus with MIC values of 4 and 8microg/mL, respectively. With Gram-negative bacteria, niloticane show...
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PMID: 20138134
PDF is available here.
PDF is available here.
Applied Spectroscopy (64)4 2010
Abstract
Raman spectra of Gram-positive and Gram-negative plant bacteria have been measured with micro-Raman spectrometers equipped with 785 and 514.5 nm lasers. The Gram-positive bacteria Microbacterium testaceum, Paenibacillus validus, and Clavibacter michiganensis subsp. michiganensis have strong caroteno...
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PMID: 20412629
PDF is available here.
PDF is available here.
Abstract
Eucalyptus oil (EO) and its major component, 1,8-cineole, have antimicrobial effects against many bacteria, including Mycobacterium tuberculosis and methicillin-resistant Staphylococcus aureus (MRSA), viruses, and fungi (including Candida). Surprisingly for an antimicrobial substance, there are also...
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PMID: 20359267
PDF is available here.
PDF is available here.
Abstract
Due to the great variability in antimicrobial resistance patterns, local reports of cumulative antimicrobial susceptibility data are necessary in every health center. The purpose is to guide clinical decisions and the early detection of patterns that allow preventive measures to avoid dissemination...
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PMID: 20556314
PDF is available here.
PDF is available here.
Abstract
Our in vitro antimicrobial susceptibility results for CEM-101 demonstrate better activity compared with other MLS(B) class agents among a diverse group of uncommonly isolated bacterial pathogens; these results provide an impetus for possible expanded indications during Phase 2 and 3 clinical trials....
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PMID: 20022192
PDF is available here.
PDF is available here.
Pharmacotherapy (30)4 2010
Abstract
Ceftaroline is a novel, broad-spectrum, advanced-generation cephalosporin whose action is mediated by binding to penicillin-binding proteins in bacteria, consistent with other beta-lactam antibiotics. Ceftaroline is distinct in that it has antimicrobial activity against multidrug-resistant Staphyloc...
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PMID: 20334458
PDF is available here.
PDF is available here.
Abstract
We observed the clinical and microbiological characteristics of several stages of bloodstream infections (BSI), as well as the mortality attributed to it in a tertiary hospital in the northeast of Brazil (in the city of Maceió, Alagoas). A prospective cohort of 143 patients who had at least one pos...
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PMID: 20563445
PDF is available here.
PDF is available here.
Abstract
Carbonyl ylide cycloaddition strategy was employed in the synthesis of platensimycin analogs. 7-Phenylplatensimycin and 11-methyl-7-phenylplatensimycin are more potent analogs of platensimycin.
2010 Elsevier Ltd. All rights reserved.
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PMID: 20207542
PDF is available here.
PDF is available here.
Journal of Antibiotics (63)4 2010
Abstract
Abstract
A series of 3,4-dihydro-2H-benzo[e]-, 2,3-dihydro-1H-naphtho[1,2-e]-, 3,4-dihydro-2H-naphtho[2,1-e][1,3]oxazine and 1,2-bis(3,4-dihydrobenzo[e][1,3]oxazin-3(4H)-yl)ethane derivatives was obtained through an eco-friendly Mannich type condensation-cyclization reaction of phenols or naphthols with form...
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PMID: 20116901
PDF is available here.
PDF is available here.
Abstract
Semicarbazide-formaldehyde resin (SFRs) was prepared by the condensation of semicarbazide with formaldehyde in an acidic medium and its polymer metal complexes were prepared with transition metal ions. All the synthesized polymers were characterized by elemental analysis, FTIR, (1)H NMR, (13)C NMR,...
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PMID: 20138409
PDF is available here.
PDF is available here.
Abstract
We synthesized, characterized and checked the antimicrobial activity of fatty acid analogs of cholesterol. The synthesized compounds were characterized using IR, (1)H NMR, (13)C NMR and mass spectral data and tested for their antimicrobial activity by disk diffusion assay with slight modifications a...
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PMID: 20106564
PDF is available here.
PDF is available here.
Abstract
As in many other developing countries, conditions that may foster antibiotic resistance in Mexico differ from developed countries, and so resistance prevalence. Fecal pollution and other traits of overcrowded, poor cities, might create ideal settings for selecting, exchanging and mai...
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PMID: 20351451
PDF is available here.
PDF is available here.
Planta Medica (76)5 2010
Abstract
The purpose of this study was to attempt the reproducible coculture of more than two fungi for biosynthesis of potential antineoplastic substances. Five different fungi were simultaneously inoculated into broth cultures and grown for two weeks. Cancer cell line bioassay-guided fractionation, NMR, an...
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PMID: 19941263
PDF is available here.
PDF is available here.
Phytopathology (100)3 2010
Abstract
The molecular interactions between Clavibacter michiganensis subsp. michiganensis and tomato plant were studied by following the expression of bacterial virulence and host-defense genes during early stages of infection. The C. michiganensis subsp. michiganensis genes included the plasmid-borne cellu...
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PMID: 20128699
PDF is available here.
PDF is available here.
Immunology (129)3 2010
Abstract
We have previously shown that intake of antigenic dietary protein is critical for inducing maturation of the immune system as well as for the development of T helper type 1 (Th1) immunity. In this study, we show that administration of an amino acid (aa)-based diet during the development of the immun...
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PMID: 20002788
PDF is available here.
PDF is available here.
Immunology (129)3 2010
Abstract
We have previously shown that intake of antigenic dietary protein is critical for inducing maturation of the immune system as well as for the development of T helper type 1 (Th1) immunity. In this study, we show that administration of an amino acid (aa)-based diet during the development of the immun...
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PMID: 20002788
PDF is available here.
PDF is available here.