Abstract
Approximately two-thirds of the patients with severe sepsis or septic shock are first encountered in the emergency departments (EDs) of western countries, in which bacteremia is present in about 50% of patients with severe sepsis. The situation of bacteremia presenting to the EDs in...
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PMID: 21524617
PDF is available here.
W Charles Huskins,
Charmaine M Huckabee,
Naomi P O'Grady,
Patrick Murray,
Heather Kopetskie,
Louise Zimmer,
Mary Ellen Walker,
Ronda L Sinkowitz-Cochran,
John A Jernigan,
Matthew Samore,
Dennis Wallace,
Donald A Goldmann and
STAR*ICU Trial Investigators
Abstract
We evaluated the effect of surveillance for MRSA and VRE colonization and of the expanded use of barrier precautions (intervention) as compared with existing practice (control) on the incidence of MRSA or VRE colonization or infection in adult ICUs. Surveillance cultures were obtained from patients...
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PMID: 21488763
PDF is available here.
Abstract
Typically, burn wound infections are classified by the organisms present in the wound within the first several days after injury or later by routine surveillance cultures. With universal acceptance of early excision and grafting, classification of burn wound colonization in unexcised...
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PMID: 21252689
PDF is available here.
Abstract
To investigate daptomycin pharmacokinetics in critically ill patients receiving continuous venovenous hemodialysis to develop dosing recommendations.
Prospective, open-label pharmacokinetic study.
: Intensive care units located within a teaching medical center.
Eight adults with known/suspected Gram...
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PMID: 20890189
PDF is available here.
Abstract
We reviewed performed a retrospective review of our series of excision arthroplasty patients and identified 16 patients who had undergone the procedure for sepsis, and who we had subsequently subjected to revision to a total hip arthroplasty (THA). Mean follow-up was 96 +/- 15 months. There was a si...
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PMID: 22167854
PDF is available here.
Abstract
We analyzed biopsies of acne lesions and healthy skin, and in vitro we used skin explants incubated with two P. acnes extracts--membrane fraction (MF) and cytosolic proteins--with or without zinc. IGF-1 and IGF-1R expression was evaluated using immunohistochemistry, and the IGF-1 production in super...
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PMID: 20927124
PDF is available here.
Abstract
We report a case of an 87-year-old Caucasian male with a history of a ruptured chordae of the anterior mitral leaflet, severe mitral regurgitation (MR), and atrial fibrillation who developed multisystem organ failure due to Gemella morbillorum native valve endocarditis without any precipitating fact...
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PMID: 21121507
PDF is available here.
Mobarak A Mraheil,
André Billion,
Carsten Kuenne,
Jordan Pischimarov,
Bernd Kreikemeyer,
Susanne Engelmann,
Axel Hartke,
Jean-Christophe Giard,
Maja Rupnik,
Sonja Vorwerk,
Markus Beier,
Julia Retey,
Thomas Hartsch,
Anette Jacob,
Franz Cemič,
Jürgen Hemberger,
Trinad Chakraborty and
Torsten Hain
Abstract
We report the current knowledge about the sRNAs of these socioeconomically relevant Gram-positive pathogens, overview the state-of-the-art high-throughput sRNA screening methods and summarize bioinformatics approaches for genome-wide sRNA identification and target prediction. Finally, we discuss the...
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PMID: 21255362
PDF is available here.
Abstract
We collected a total of 1000 urine samples, and 325 of these samples tested positive for a UTI via traditional culturing techniques; additionally, all 325 of these samples tested positive with the Eub338 probe in FISH analysis. FISH analyses with species-specific probes were performed in parallel to...
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PMID: 20807557
PDF is available here.
Abstract
We report a clinical isolate of Enterococcus faecium in which three distinct and excision-proficient copies of Tn916-like elements are present in the genome. All of the elements contain tet(M) genes, at least one of which confers resistance to tetracycline and minocycline. Two elements (Tn6085a, Tn6...
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PMID: 20600284
PDF is available here.
Abstract
Strain KIT 00200-70066-1(T) was isolated from the sputum of a patient with pulmonary disease. Cells of the strain were Gram-variable, facultatively anaerobic, motile, spore-forming rods and formed colourless to white colonies on tryptic soy agar at 30 °C and pH 7. The pathogenicity of...
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PMID: 19946060
PDF is available here.
Abstract
A controlled environment poultry house (1600m(2)) was divided into two separated compartments. Three hundred twenty chick containers (each containing 100 chicks) were randomly allocated to each compartment. Antimicrobial products were provided (via drinking water) to one broiler group in three diffe...
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PMID: 19822372
PDF is available here.
Abstract
We performed an 8-year retrospective study of all hospitalized patients with recurrent VRE colonization after they were documented as being clear of VRE and compared the primary colonization isolates and recolonization isolates by pulsed-field gel electrophoresis and Tn1546 typing. Review of the med...
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PMID: 20109265
PDF is available here.
Abstract
This descriptive study was conducted in a public hospital from May 2005 to October 2007, with the purpose to determine the epidemiological aspects that involve vancomycin-resistant enterococci (VRE) and describe the evolution of patients. The data was obtained from registers on patient records and t...
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PMID: 20964050
PDF is available here.
Abstract
A 64-year-old man with prostate cancer and bone metastasis admitted for nausea, left abdominal pain showed no abnormal, and fever, abdominal ultrasound or chest X-ray findings. Despite antibiotics, left abdominal pain persisted for several days. Abdominal computed tomography (CT), showed splenic inf...
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PMID: 20960939
PDF is available here.
Abstract
We suggest microbiological and histological testing of ovarian tissue as mandatory tools to guarantee safety regarding ovarian tissue transplantation.
Crown Copyright 2010. Published by Elsevier Ireland Ltd. All rights reserved....
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PMID: 20580151
PDF is available here.
Abstract
The cutaneous infectious pathology of the child is varied and frequent. Authors deal with surgical infections seen in current pediatrics, which often have to appeal to a plastic pediatric surgeon for their treatment. Superficial infections of skin and pilo-sebaceous follicles are common in big child...
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PMID: 20691574
PDF is available here.
Abstract
The spinal canal is divided into epidural, subdural and subarachnoid spaces. Intraspinal processes should be correctly placed into their space of origin. MRI is the best imaging modality to achieve this task. Accurate determination of the space of origin routinely requires the acquisition of two dif...
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PMID: 20814388
PDF is available here.
Abstract
Gram-positive bacteria such as Staphylococcus aureus have been a common cause of infection among liver transplant (LT) recipients in recent decades. The understanding of local epidemiology and its evolving trends with regard to pathogenic spectra and antibiotic susceptibility is beneficial to prophy...
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PMID: 20819529
PDF is available here.
Abstract
Of the 60 patients, 88.3% had monomicrobial infection and 11.7% had mixed infection. The mean duration from the first neurosurgical procedure to the diagnosis of meningitis was 21 days (range, 1-134 days). The median frequency of neurosurgical procedure before meningitis was 1 (range, 1-5). A total...
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PMID: 20688290
PDF is available here.
Abstract
MICs of imipenem and colistin for E. cloacae strain Ent 831 were 0.5 microg/mL and 1.0 microg/mL, respectively. Using a standard inoculum (5 x 10(5)) CFU/mL), synergism was shown with a concentration of two times the MICs of imipenem and colistin. Furthermore, four times the MIC of imipenem complete...
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PMID: 20688292
PDF is available here.
Abstract
Bacterial infection shortly after mating interferes with establishment of pregnancy. Injection of peptidoglycan-polysaccharide (PG-PS), a component of gram-positive bacteria, into sheep on day 5 after mating reduces pregnancy rate. Experiments were designed to evaluate the acute-phase response (APR)...
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PMID: 20603027
PDF is available here.
Abstract
We report what we believe to be the first confirmed Neosartorya hiratsukae CAPD-related peritonitis case in Europe. The patient died, despite early removal of the peritoneal catheter and antifungal therapy. This report highlights the impact of emerging fungal pathogens and the importance of early di...
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PMID: 20395379
PDF is available here.
Marco Fossati,
Barbara Cappelli,
Erika Biral,
Robert Chiesa,
Alessandra Biffi,
Cristina Ossi,
Matteo Moro,
Daniela Maria Cirillo,
Massimo Clementi,
Clara Soliman,
Fabio Ciceri,
Maria Grazia Roncarolo,
Luca Fumagalli and
Sarah Marktel
Abstract
We report what we believe to be the first case of a child with prolonged bone marrow aplasia following haematopoietic stem cell transplantation developing a fatal sepsis caused by Enterococcus faecium resistant to glycopeptides and linezolid....
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PMID: 20299507
PDF is available here.
Abstract
Although Gram-negative bacteria are the most common etiology of fever in neutropenic patients, the occurrence of infections caused by coagulase-negative Staphylococcus and molds has been increasing in comparison with the observations from previous studies in King Chulalongkorn Memorial Hospital. To...
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PMID: 20649055
PDF is available here.
Abstract
Non-faecalis and non-faecium Enterococcus species can cause protean manifestations which vary with the infecting Enterococcus species. Misidentification of unusual enterococcal species might occur by the commercial identification methods and accurate identification with molecular methods is required...
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PMID: 20433865
PDF is available here.
Abstract
We included 190 patients treated with 526 cycles of chemotherapy. The follow-up period was 6 months from the diagnosis of AML. Prophylactic antibiotics were not used. We identified 604 febrile episodes with 246 episodes of sepsis. Thirty-two patients (17%) either died from infection or infection was...
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PMID: 20331735
PDF is available here.
Abstract
Traditionally, pneumonia developing in patients who receive health care services in the outpatient environment, such as nursing homes, long-term care facilities, and dialysis centers, has been classified and treated as community-acquired pneumonia (CAP). Recent studies, however, have shown that this...
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PMID: 20499775
PDF is available here.
Laurie R Solomon,
John S Cheesbrough,
Leonard Ebah,
Tamer Al-Sayed,
Michael Heap,
Nick Millband,
Dee Waterhouse,
Sandip Mitra,
Alan Curry,
Rema Saxena,
Rammohan Bhat,
Michael Schulz and
Peter Diggle
Abstract
Taurolidine-citrate use did not decrease all-cause bacteremia and was associated with a greater need for thrombolytic treatment. There was a decrease in infections caused by Gram-negative organisms and a trend to a lower frequency of bacteremia, which warrants further study.
Copyright 2010 National...
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PMID: 20207458
PDF is available here.
P Durando,
M Bassetti,
G Orengo,
P Crimi,
A Battistini,
G Tiberio,
D Bellina,
A Talamini,
F Dodi,
F Ansaldi,
C Alicino,
R Iudici,
L Sticchi,
D De Florentiis,
C Viscoli,
G Icardi and
Prevalence Study Working Group of the San Martino University Hospital of Genoa
Abstract
A prevalence study aimed to update the epidemiological scenario of Hospital-Acquired Infections (HAI) was performed at the San Martino University Hospital of Genoa, the Regional Reference Adult-care Center in Liguria, Italy, with more than 1300 beds.
The investigation was performed in all the wards,...
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PMID: 21155410
PDF is available here.
Abstract
We observed difficulties in controlling colonization with measures directed mainly by surveillance cultures and differences between responses of E faecium and E faecalis.
Copyright 2010 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Mosby, Inc. All rights rese...
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PMID: 20006408
PDF is available here.
Abstract
A quadruplex real-time (RT) qPCR assay for the detection and quantification in 4h of Staphylococcusaureus, Pseudomonasaeruginosa, Acinetobacterbaumannii and Stenotrophomonasmaltophilia directly from bronchoalveolar lavage specimens was developed. The specificity of the assay was 100% for all four sp...
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PMID: 20353803
PDF is available here.
Abstract
Health care-associated infections (HAI) remain a major cause of patient morbidity and mortality. Although the main source of nosocomial pathogens is likely the patient's endogenous flora, an estimated 20% to 40% of HAI have been attributed to cross infection via the hands of health care personnel, w...
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PMID: 20569853
PDF is available here.
Abstract
Dalbavancin, oritavancin and telavancin are semisynthetic lipoglycopeptides that demonstrate promise for the treatment of patients with infections caused by multi-drug-resistant Gram-positive pathogens. Each of these agents contains a heptapeptide core, common to all glycopeptides, which enables them...
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PMID: 20426497
PDF is available here.
Abstract
Anaerobic bacteria are the predominant indigenous flora of humans and, as a result, play an important role in infections, some of which are serious with a high mortality rate. These opportunistic pathogens are frequently missed in cultures of clinical samples because of shortcomings in collection an...
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PMID: 20426496
PDF is available here.
Abstract
We prospectively analysed the microbiological isolates of all febrile/infectious episodes occurring at our haematology unit during 2 consecutive 18-month periods. Microbiologically documented infections (MDI) and antibiotic resistance were correlated with type and status of haematological disease, n...
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PMID: 20100118
PDF is available here.
Abstract
Even when an adequate seal of the apical foramen was shown by the absence of turbidity in the bacterial leakage test, E. faecalis dentin infection was present in a high percentage of the root canals after 120 days of root filling exposure to the bacteria. Tagger's hybrid technique presented greater...
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PMID: 20416539
PDF is available here.
Abstract
Streptococcus (54.5%), Neisseria (14.7%), Actinomyces (8.4%), Gemella (4.1%), Granulicatella (3.8%), and Prevotella (1.4%) were dominant in a total of 1655 clones examined from the saliva of the healthy subjects. The dominant genera differed among the patients with odontogenic infections (a total of...
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PMID: 20171911
PDF is available here.
Diana Panesso,
Jinnethe Reyes,
Sandra Rincón,
Lorena Díaz,
Jessica Galloway-Peña,
Jeannete Zurita,
Carlos Carrillo,
Altagracia Merentes,
Manuel Guzmán,
Javier A Adachi,
Barbara E Murray and
Cesar A Arias
Abstract
Enterococcus faecium has emerged as an important nosocomial pathogen worldwide, and this trend has been associated with the dissemination of a genetic lineage designated clonal cluster 17 (CC17). Enterococcal isolates were collected prospectively (2006 to 2008) from 32 hospitals in Colombia, Ecuador...
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PMID: 20220167
PDF is available here.
Abstract
Two of 20 TGCR pigs died immediately (unrecognized preoperative autopsy-proven pneumonia). The median procedure times were 70.5 and 19.0 minutes for TGCR and LCR, respectively; weight gains were 7.1 and 8.2 kg, respectively. The median adhesion scores were 4.3 and 3.7, respectively (P = .26); subsco...
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PMID: 20170909
PDF is available here.
Abstract
We describe a rare case of a 53-year-old man with a long history of alcohol abuse, with Enterococcus gallinarum meningitis, an organism that rarely causes human infection and is primarily found in the gastrointestinal tract of poultry. The patient improved with high-dose ampicillin and gentamicin th...
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PMID: 20464133
PDF is available here.
Abstract
The transmission of multidrug-resistant organisms (MRSA, VRE and ESBL producing bacteria) occurs predominantly if health-care workers are not compliant with hand hygiene procedures. The impact of single-room isolation in transmission prevention is often overestimated. As long as hand disinfection is...
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PMID: 20379942
PDF is available here.
Abstract
Infected mesh after laparoscopic ventral herniorrhapy without systemic sepsis may be amenable to nonoperative treatment. A conservative approach that includes percutaneous drainage followed by antibiotic irrigation is a potential alternative to prosthetic removal in carefully selected patients. Furt...
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PMID: 20156120
PDF is available here.
Abstract
We describe an unusual case of Lactobacillus casei bacteraemia in a heavy dairy consumer woman, with a one month history of low grade fever and admitted to our hospital for sudden onset of severe thoracic pain due to dissection of the aortic arch and ascending aorta. The patient underwent four weeks...
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PMID: 20518281
PDF is available here.
Abstract
We report for the first time that many clinical isolates of Enterococcus faecalis, a common pathogen in infective endocarditis, aggregate human platelets. 84 isolates from human blood and urine were screened for their ability to aggregate platelets from four different donors. Platelet aggregation oc...
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PMID: 20109578
PDF is available here.
Abstract
Carbonyl ylide cycloaddition strategy was employed in the synthesis of platensimycin analogs. 7-Phenylplatensimycin and 11-methyl-7-phenylplatensimycin are more potent analogs of platensimycin.
2010 Elsevier Ltd. All rights reserved.
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PMID: 20207542
PDF is available here.
Abstract
It clearly appears that the percentage of patients with P. acnes strains resistant to erythromycin is similar to that in other countries, but lower for tetracycline or doxycycline in comparison to other European countries....
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PMID: 20465665
PDF is available here.
Abstract
It is worth emphasizing that airway support is the priority in patients with deep neck infections. Empirical antibiotic treatments must cover gram-positive and gram-negative aerobic and anaerobic pathogens. Surgical exploration and drainage may be mandatory in selected cases at presentation or in ca...
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PMID: 20392031
PDF is available here.
Abstract
Rainbow trout gastroenteritis (RTGE) is an emerging syndrome linked to the presence of large numbers of the segmented filamentous bacterium "Candidatus arthromitus" within the intestine. The present study examined the histopathological changes of the digestive tract of 152 trout with...
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PMID: 20106826
PDF is available here.
Abstract
Rainbow trout gastroenteritis (RTGE) is an emerging syndrome linked to the presence of large numbers of the segmented filamentous bacterium "Candidatus arthromitus" within the intestine. The present study examined the histopathological changes of the digestive tract of 152 trout with...
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PMID: 20106826
PDF is available here.
Abstract
Rainbow trout gastroenteritis (RTGE) is an emerging syndrome linked to the presence of large numbers of the segmented filamentous bacterium "Candidatus arthromitus" within the intestine. The present study examined the histopathological changes of the digestive tract of 152 trout with...
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PMID: 20106826
PDF is available here.