Abstract
We used national Medicare data to calculate the performance of hospitals on 11 medical and surgical PSIs. We designated US hospitals in the top decile of proportion of hospitalized patients who are black as "black-serving." We calculated overall and race-specific rates and examined the relationship...
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PMID: 21063225
PDF is available here.
Abstract
We describe the clinical course and outcome of patients with A. actinomycetemcomitans infection.
All patients suffering invasive A. actinomycetemcomitans infections at the National Taiwan University Hospital from January 1985 to December 2004 were included in this study. Relevant dat...
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PMID: 21195976
PDF is available here.
Abstract
These results confirm that the liver plays an important role in initiating and orchestrating the innate immune response to A. pleuropneumoniae infection....
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PMID: 19710094
PDF is available here.
S J Olsen,
S Thamthitiwat,
S Chantra,
M Chittaganpitch,
A M Fry,
J M Simmerman,
H C Baggett,
T C T Peret,
D Erdman,
R Benson,
D Talkington,
L Thacker,
M L Tondella,
J Winchell,
B Fields,
W L Nicholson,
S Maloney,
L F Peruski,
K Ungchusak,
P Sawanpanyalert and
S F Dowell
Abstract
Although pneumonia is a leading cause of death from infectious disease worldwide, comprehensive information about its causes and incidence in low- and middle-income countries is lacking. Active surveillance of hospitalized patients with pneumonia is ongoing in Thailand. Consenting patients are teste...
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PMID: 20353622
PDF is available here.
Abstract
Community-acquired pneumonia (CAP) is a major clinical problem in terms of morbidity, mortality, and use of hospital resources. It is well recognized that a delay in making the diagnosis and instituting appropriate antibiotic treatment is associated with an increased mortality. C-reactive protein ma...
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PMID: 21140960
PDF is available here.
Abstract
Our results confirm that the upper respiratory tract acts as an important reservoir of P aeruginosa colonization and infection in the mechanically ventilated patients and emphasize the importance of exogenous acquisition of P aeruginosa. A combination of early identification and eradication of airwa...
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PMID: 20627453
PDF is available here.
Abstract
We credit this patient's recovery to our facility's heightened surveillance for influenza even among the vaccinated individuals, and also in those without classic influenza-like illness....
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PMID: 21053711
PDF is available here.
Abstract
To report a case of recurrent Stenotrophomonas maltophilia ventilator-associated pneumonia (VAP) that was successfully treated with doxycycline and aerosolized colistin.
A 28-year-old male was admitted with a severe head injury and required mechanical ventilation. The patient developed S. maltophili...
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PMID: 20736426
PDF is available here.
Abstract
We determined peak and trough serum TMP and SMX concentrations and the extent of TMP/SMX CVVHDF clearance at steady-state while the patients were still anuric and oliguric.
Data on TMP and SMX pharmacokinetics in CVVHDF are lacking and dosing recommendations are inconclusive. In both patients, CVVHD...
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PMID: 20823279
PDF is available here.
Abstract
Oral decontamination with chlorhexidine prevents accumulation of pathogens in the oral cavity, and can thereby reduce the risk of translocation to and colonization of the lungs. The antiseptic agent chlorhexidine has been widely used in dentistry, it has an excellent record of safety and efficacy an...
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PMID: 20882081
PDF is available here.
Abstract
The aim of this study was to examine the clinical usefulness of serial C-reactive protein (CRP) dosages in patients with nosocomial pneumonia (NP).
Prospective and observational study performed in a 24-beds Intensive Care Unit. Sixty four patients with NP, including non-ventilated patients and those...
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PMID: 20600303
PDF is available here.
Abstract
We therefore analyzed the dynamics of multiple chemokines, which are frequently associated with type 1 (Th1) T cell immune responses, and their receptors for their expression in the lungs during Chlamydia muridarum (Cm) infections. We also examined the relationship between chemokine responses and th...
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PMID: 20622889
PDF is available here.
Abstract
We conducted an observational, cross sectional study between June 2007 and June 2008 in 100 ESRD patients half being > 65 yrs. All patients had positive sputum culture and chest X-ray findings of pneumonia Streptococcus pneumoniae was the commonest in younger while Klebsiella pneumoniae in > 65 yrs...
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PMID: 20814127
PDF is available here.
Abstract
A 25-yr-old male freshwater crocodile (Crocodylus johnstoni) was diagnosed with pulmonary mycobacteriosis caused by Mycobacterium szulgai. Necropsy revealed fibrinous exudate in the right pleural cavity and white miliary nodules in the right lung lobe. Histopathologic examination revealed well-demar...
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PMID: 20945661
PDF is available here.
Abstract
We accessed findings and data from published and unpublished cefepime clinical trials.
We performed meta-analyses using trial- and patient-level data from comparative trials. Trial-level analyses were performed using summary data from all patients in the trials, and patient-level analyses were perfo...
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PMID: 20624065
PDF is available here.
Abstract
MICs of imipenem and colistin for E. cloacae strain Ent 831 were 0.5 microg/mL and 1.0 microg/mL, respectively. Using a standard inoculum (5 x 10(5)) CFU/mL), synergism was shown with a concentration of two times the MICs of imipenem and colistin. Furthermore, four times the MIC of imipenem complete...
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PMID: 20688292
PDF is available here.
Abstract
We further characterize this domain by identifying six residues that are essential for ExoU activity. Substitutions at each of these positions resulted in abrogation of membrane targeting, decreased ExoU-mediated cytotoxicity, and reductions in PLA(2) activity. Likewise, each of the six MLD residues...
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PMID: 20479080
PDF is available here.
Abstract
We conducted a prospective study of patients with CAP hospitalized at HaEmek Medical Center, Afula. We collected demographic, clinical and laboratory data (blood and sputum cultures, serology, pneumococcal urinary antigen test, and respiratory multiplex-polymerase chain reaction from nasopharyngeal...
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PMID: 21337816
PDF is available here.
Abstract
We report a case of pulmonary mucormycosis in which mixed infection with A. fumigatus was suspected. Pulmonary mucormycosis is a life-threatening infection in which it is rare that an antemortem diagnosis is established and organisms are isolated. We believe diagnostic tests should be performed aggr...
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PMID: 20803983
PDF is available here.
Masanori Nakanishi,
Yoshimasa Yoshida,
Nobuya Takeda,
Hirohumi Hirana,
Takahiro Horita,
Kazuhiko Shimizu,
Kazuyuki Hiratani,
Shigeo Toyoda,
Takayuki Matsumura,
Eizi Shinno,
Satoru Kawai,
Akihiro Futamura,
Masanari Ota and
Toshiki Natazuka
Abstract
Progression of symptoms was a significant factor for predicting CAP and selecting patients who required CXR. Inclusion of progression of symptoms among the other recommended criteria, namely, dyspnoea, fever > 38 degrees C, heart rate > 100 beats/min and abnormal chest findings, improved prediction...
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PMID: 20630031
PDF is available here.
Abstract
We report two children with cystic fibrosis who underwent a comprehensive assessment from diagnosis that included measurement of lung function, limited-slice high-resolution CT and BAL performed annually. Early aggressive surveillance enabled significant lung disease and bronchiectasis to be detecte...
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PMID: 20456672
PDF is available here.
Abstract
The aim of this study was to compare outcomes for patients with community-acquired pneumonia (CAP) caused by Legionella spp. following treatment with moxifloxacin or a range of comparator antimicrobial agents. Data were pooled from four sequential I.V./P.O. trials of moxifloxacin in the treatment of...
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PMID: 20685631
PDF is available here.
Abstract
We evaluated the effect of the TLR5 ligand flagellin on stimulation of antibacterial mucosal immunity in a lethal murine Pseudomonas aeruginosa pneumonia model. The intranasal pretreatment of mice with purified P. aeruginosa flagellin induced strong protection against intratracheal P. aeruginosa-ind...
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PMID: 20566829
PDF is available here.
Abstract
Cavitary pneumonia caused by Rhodococcus equi may occur in patients with defective cell-mediated immunity. Prolonged CD4 lymphopenia may develop in patients with chronic lymphocytic leukemia who receive fludarabine. The authors report the first case of a patient with chronic lymphocytic leukemia who...
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PMID: 20463575
PDF is available here.
Abstract
I (NMI), SCID mice developed pneumonia and splenomegaly and succumbed to infection, whereas wild-type mice cleared the infection by 24 days. SCID mice reconstituted with either CD4+ T cells or CD8+ T cells alone were able to control the infection, indicating that the presence of either type of T cel...
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PMID: 20351144
PDF is available here.
Abstract
We report, for what is believed to be the first time, a case of severe pneumonia in a cancer patient caused by Aeromonas caviae. Detailed microbiological investigation revealed that this isolate carried three beta-lactamase-encoding genes (encoding MOX-4, CTX-M-3 and TEM-1) conferring resistance to...
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PMID: 20339022
PDF is available here.
Abstract
Study patients were divided into two groups: 61 patients with bacterial infection and 26 patients without it. Semi-quantitative PCT test (cut-off value; > or = 0.5 ng/ml) showed sensitivity of 55.7% and specificity of 84.6% for diagnosis of bacterial infection. The diagnostic value of PCT was higher...
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PMID: 20715510
PDF is available here.
Abstract
We evaluated the effectiveness of NIs in reducing influenza complications and mortality of patients with seasonal influenza, by performing a meta-analysis of randomized controlled trials (RCTs), retrieved from PubMed, Cochrane Central Register of Controlled Trials and Scopus databases, comparing NIs...
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PMID: 20488984
PDF is available here.
Abstract
Emergence of multidrug-resistant strains in intensive care units has renewed interest in colistin, which often remains the only available antimicrobial agent active against resistant Pseudomonas aeruginosa. The aim of this study is to compare lung tissue deposition and antibacterial...
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PMID: 20397007
PDF is available here.
Abstract
Intracellular bacteria are common causes of community-acquired pneumonia that grow poorly or not at all on standard culture media and do not respond to beta-lactam antibiotic therapy. Apart from well-established agents of pneumonia such as Legionella pneumophila, Mycoplasma pneumoniae, Chlamydia pne...
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PMID: 20586563
PDF is available here.
Abstract
Our objective was to evaluate the efficacy of noninvasive continuous positive airway pressure (CPAP) delivered by helmet in improving oxygenation in comparison with oxygen therapy in community-acquired pneumonia (CAP).
This was a multicenter, randomized, controlled trial enrolling pa...
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PMID: 20154071
PDF is available here.
Abstract
Our objective was to evaluate the efficacy of noninvasive continuous positive airway pressure (CPAP) delivered by helmet in improving oxygenation in comparison with oxygen therapy in community-acquired pneumonia (CAP).
This was a multicenter, randomized, controlled trial enrolling pa...
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PMID: 20154071
PDF is available here.
Abstract
Our objective was to evaluate the efficacy of noninvasive continuous positive airway pressure (CPAP) delivered by helmet in improving oxygenation in comparison with oxygen therapy in community-acquired pneumonia (CAP).
This was a multicenter, randomized, controlled trial enrolling pa...
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PMID: 20154071
PDF is available here.
Abstract
Our objective was to evaluate the efficacy of noninvasive continuous positive airway pressure (CPAP) delivered by helmet in improving oxygenation in comparison with oxygen therapy in community-acquired pneumonia (CAP).
This was a multicenter, randomized, controlled trial enrolling pa...
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PMID: 20154071
PDF is available here.
Abstract
Our objective was to evaluate the efficacy of noninvasive continuous positive airway pressure (CPAP) delivered by helmet in improving oxygenation in comparison with oxygen therapy in community-acquired pneumonia (CAP).
This was a multicenter, randomized, controlled trial enrolling pa...
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PMID: 20154071
PDF is available here.
Abstract
Our objective was to evaluate the efficacy of noninvasive continuous positive airway pressure (CPAP) delivered by helmet in improving oxygenation in comparison with oxygen therapy in community-acquired pneumonia (CAP).
This was a multicenter, randomized, controlled trial enrolling pa...
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PMID: 20154071
PDF is available here.
Abstract
Our objective was to evaluate the efficacy of noninvasive continuous positive airway pressure (CPAP) delivered by helmet in improving oxygenation in comparison with oxygen therapy in community-acquired pneumonia (CAP).
This was a multicenter, randomized, controlled trial enrolling pa...
|
PMID: 20154071
PDF is available here.
Abstract
Our objective was to evaluate the efficacy of noninvasive continuous positive airway pressure (CPAP) delivered by helmet in improving oxygenation in comparison with oxygen therapy in community-acquired pneumonia (CAP).
This was a multicenter, randomized, controlled trial enrolling pa...
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PMID: 20154071
PDF is available here.
Abstract
Our objective was to evaluate the efficacy of noninvasive continuous positive airway pressure (CPAP) delivered by helmet in improving oxygenation in comparison with oxygen therapy in community-acquired pneumonia (CAP).
This was a multicenter, randomized, controlled trial enrolling pa...
|
PMID: 20154071
PDF is available here.
Abstract
Our objective was to evaluate the efficacy of noninvasive continuous positive airway pressure (CPAP) delivered by helmet in improving oxygenation in comparison with oxygen therapy in community-acquired pneumonia (CAP).
This was a multicenter, randomized, controlled trial enrolling pa...
|
PMID: 20154071
PDF is available here.
Abstract
Our objective was to evaluate the efficacy of noninvasive continuous positive airway pressure (CPAP) delivered by helmet in improving oxygenation in comparison with oxygen therapy in community-acquired pneumonia (CAP).
This was a multicenter, randomized, controlled trial enrolling pa...
|
PMID: 20154071
PDF is available here.
Abstract
Our objective was to evaluate the efficacy of noninvasive continuous positive airway pressure (CPAP) delivered by helmet in improving oxygenation in comparison with oxygen therapy in community-acquired pneumonia (CAP).
This was a multicenter, randomized, controlled trial enrolling pa...
|
PMID: 20154071
PDF is available here.
Abstract
Our objective was to evaluate the efficacy of noninvasive continuous positive airway pressure (CPAP) delivered by helmet in improving oxygenation in comparison with oxygen therapy in community-acquired pneumonia (CAP).
This was a multicenter, randomized, controlled trial enrolling pa...
|
PMID: 20154071
PDF is available here.
Abstract
Our objective was to evaluate the efficacy of noninvasive continuous positive airway pressure (CPAP) delivered by helmet in improving oxygenation in comparison with oxygen therapy in community-acquired pneumonia (CAP).
This was a multicenter, randomized, controlled trial enrolling pa...
|
PMID: 20154071
PDF is available here.
Abstract
Our objective was to evaluate the efficacy of noninvasive continuous positive airway pressure (CPAP) delivered by helmet in improving oxygenation in comparison with oxygen therapy in community-acquired pneumonia (CAP).
This was a multicenter, randomized, controlled trial enrolling pa...
|
PMID: 20154071
PDF is available here.
Abstract
Our objective was to evaluate the efficacy of noninvasive continuous positive airway pressure (CPAP) delivered by helmet in improving oxygenation in comparison with oxygen therapy in community-acquired pneumonia (CAP).
This was a multicenter, randomized, controlled trial enrolling pa...
|
PMID: 20154071
PDF is available here.
Abstract
Our objective was to evaluate the efficacy of noninvasive continuous positive airway pressure (CPAP) delivered by helmet in improving oxygenation in comparison with oxygen therapy in community-acquired pneumonia (CAP).
This was a multicenter, randomized, controlled trial enrolling pa...
|
PMID: 20154071
PDF is available here.
Abstract
Our objective was to evaluate the efficacy of noninvasive continuous positive airway pressure (CPAP) delivered by helmet in improving oxygenation in comparison with oxygen therapy in community-acquired pneumonia (CAP).
This was a multicenter, randomized, controlled trial enrolling pa...
|
PMID: 20154071
PDF is available here.
Abstract
Our objective was to evaluate the efficacy of noninvasive continuous positive airway pressure (CPAP) delivered by helmet in improving oxygenation in comparison with oxygen therapy in community-acquired pneumonia (CAP).
This was a multicenter, randomized, controlled trial enrolling pa...
|
PMID: 20154071
PDF is available here.
Abstract
Our objective was to evaluate the efficacy of noninvasive continuous positive airway pressure (CPAP) delivered by helmet in improving oxygenation in comparison with oxygen therapy in community-acquired pneumonia (CAP).
This was a multicenter, randomized, controlled trial enrolling pa...
|
PMID: 20154071
PDF is available here.
Abstract
Our objective was to evaluate the efficacy of noninvasive continuous positive airway pressure (CPAP) delivered by helmet in improving oxygenation in comparison with oxygen therapy in community-acquired pneumonia (CAP).
This was a multicenter, randomized, controlled trial enrolling pa...
|
PMID: 20154071
PDF is available here.