Abstract
Actions of 5alpha-pregnan-3alpha-ol-20-one (3alpha,5alpha-THP), in the midbrain ventral tegmental area (VTA) modulate sexual receptivity of female rats. Actions of 3alpha,5alpha-THP at GABAergic substrates in the VTA are known to modulate consummatory aspects of sexual behavior among rodents, such a...
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PMID: 19576238
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Abstract
Our results indicate that FAAH inhibitors could be potent modulators of motivational and conditioned aspects of goal-directed behaviors with less prominent effects on consumatory behaviors....
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PMID: 19826190
PDF is available here.
Abstract
These results suggest that distinct aspects of the addiction process can be parsed using self-administration models, thereby facilitating the investigation of specific neurobiological adaptations that occur through the addiction process....
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PMID: 18971927
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Abstract
A series of experiments studied the effects of the kappa-opioid receptor agonist U50,488H on consummatory successive negative contrast (cSNC) in rats. In cSNC, previous experience with a 32% sucrose solution leads to greater rejection of 4% sucrose than exclusive experience with 4% sucrose. Experime...
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PMID: 18514923
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Abstract
Aplysia egg laying is a complex behavior requiring synchronized activity in many organs. Aspects of the behavior are synchronized via the direct effects of peptide bag cell neurohormones and via stimuli arising during the behavior. Stimuli synchronizing egg laying were examined by treating A. fascia...
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PMID: 18626072
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Abstract
These data suggest that antagonism of the CB(1) receptor facilitates ejaculatory processes, an effect which may be due to interactions with neuropeptidergic systems in the hypothalamus, and further, suggest a novel target for pharmacological agents aimed at treating ejaculatory-based sexual dysfunct...
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PMID: 17694389
PDF is available here.
Abstract
We attempted to identify the contribution of the selective deprivation of physical contact to the emergence of the isolation syndrome. To this end, we devised a pseudoisolated housing condition in which male 3-week-old C57BL/6 mice were caged in pairs, but were separated by a transparent perforated...
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PMID: 18513121
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Abstract
We investigate the effects of these rearing conditions on sucrose consumption and preference, and tissue levels of striatal dopamine. The possible relationship among sucrose intake, immobility behavior in the forced swimming test, and dopamine concentration was explored through correlation and regre...
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PMID: 18400393
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Abstract
Ghrelin, an endogenous ligand for the growth-hormone-secretagogue receptor, is a 28-amino acid peptide with a post-translational acyl modification necessary for its activity. It has central nervous system actions that affect appetite, body mass and energy balance. An intracerebroventricular (ICV) in...
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PMID: 18280592
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Abstract
Previous findings have demonstrated that the maternal environment is important for the development of male sexual behavior. The present study examined the effects of complete early life isolation and replacement 'stroking' stimulation on male sexual behavior and neural activation as seen by Fos immu...
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PMID: 18335501
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Abstract
We used a task featuring balanced incentive delivery and an analytic strategy designed to identify activity specific to anticipation or consumption. Reaction time data in two independent samples (n=13 and n=8) confirmed motivated responding. Functional magnetic resonance imaging revealed regions act...
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PMID: 17850241
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Abstract
Several studies have suggested dissociations between neural circuits underlying the expression of appetitive (e.g., courtship behavior) and consummatory components (i.e., copulatory behavior) of vertebrate male sexual behavior. The medial preoptic area (mPOA) clearly controls the expression of male...
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PMID: 17624413
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Abstract
Although systemic allopregnanolone (ALLO; a positive modulator of GABA(A) receptors) has been shown to enhance ethanol-reinforced responding and to modulate drinking patterns in rodents, the effects of centrally administered ALLO on ethanol intake are not known. The current work examined the effects...
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PMID: 17376546
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Abstract
We examined the reinforcer-specificity of Pavlovian conditioning in the control of appetitive and consummatory behaviors in Pavlovian-to-instrumental transfer, cue-potentiated eating, and devaluation procedures. Rats received pairings of one conditioned stimulus with sucrose and another conditioned...
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PMID: 17346758
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Abstract
The heuristic framework outlined above may help explain why dopamine-compromising manipulations that strongly diminish instrumental goal-seeking behaviors leave consummatory activity relatively unaffected....
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PMID: 17318502
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Abstract
Altogether, the data presented point out for an implication of dopamine in the anticipatory/preparatory aspects of feeding more than on the motivational and consummatory aspects. However, dopamine involvement in the anticipatory/preparatory component of feeding seems specifically related to very rel...
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PMID: 17031710
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Abstract
These results suggest that the separation of appetitive and consummatory phases of ethanol self-administration may prove useful in future evaluations of the pharmacological and genetic bases of ethanol reinforcement in mice....
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PMID: 17452296
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Abstract
We used a consummatory contrast paradigm to manipulate the relative value of a sucrose solution for two groups of rats. Systemic injection of the nonspecific opioid antagonist naltrexone suppressed sucrose intake; for both groups, however, this suppression was selective, occurring only for the relat...
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PMID: 16925586
PDF is available here.
Abstract
We conclude that olfaction plays a major role when D. platura females are searching for oviposition sites. Volatile compounds released from germinating beans such as 4-hydroxy-4-methyl-2-pentanone, 1-hepten-3-one, 1-octen-3-ol, and 3-octanone should be considered as key compounds that mediate ovipos...
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PMID: 16718565
PDF is available here.
Abstract
Increased ingestion of ethanol by RIIbeta(-/-) mice is likely the result of altered PKA activity within neuronal pathways that control ethanol-consummatory behaviors. Conversely, the RIIbeta subunit of PKA appears not to play a critical role in neuronal pathways that regulate appetitive behaviors di...
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PMID: 16634851
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Abstract
Overall, baclofen treatment affected reinforcer intake at doses that had no effect on reinforcer seeking, and effective doses decreased both sucrose seeking and ethanol seeking. Moreover, the effects on reinforcer intake were disparate, in that baclofen increased ethanol drinking and decreased sucro...
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PMID: 16634849
PDF is available here.
Abstract
We investigated the neural sites related to the occurrence of appetitive (ASB) and consummatory (CSB) aspects of male sexual behaviour in Japanese quail. Castrated males treated with testosterone were exposed for 5 min to one of four experimental conditions: (i) free interaction with a female (CSB g...
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PMID: 16623844
PDF is available here.
Abstract
These results support the hypothesis that corticosterone strengthens an aversive emotional component elicited by the surprising downshift in reward magnitude during the initial downshift trial.
((c) 2006 APA, all rights reserved)....
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PMID: 16719701
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Abstract
We report the development of D1A2A receptor knockout mice to investigate whether interactions between dopamine D1 and adenosine A2A receptors participate in reward-related behavior. The combined deletion of D1 and A2A receptors resulted in mice with decreased weight and appetitive processes, reduced...
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PMID: 16123762
PDF is available here.
Abstract
In consummatory successive negative contrast, rats that have had experience drinking 32% sucrose solution drink significantly less 4% sucrose solution than rats that have drunk only 4% solution. This contrast effect occurs reliably when rats are housed in wire-bottom cages, but it occurs significant...
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PMID: 16505824
PDF is available here.
Abstract
This study examined how sibutramine (0.06-4.0 mg/kg, i.m.), a clinically effective weight-loss medication which increases extracellular serotonin and norepinephrine levels, affected the appetitive and consummatory aspects of feeding of non-human primates. The effects were compared to the effects of...
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PMID: 16352322
PDF is available here.
Abstract
Non-genomic effects of steroid hormones on cell physiology have been reported in the brain. However, relatively little is known about the behavioral significance of these actions. Male sexual behavior is activated by testosterone partly through its conversion to estradiol via the enzyme aromatase in...
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PMID: 15963995
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Abstract
Three experiments explored the role of the opioid system in consummatory successive negative contrast. In Experiment 1, rats treated with the nonspecific opioid-receptor antagonist naloxone (2mg/kg) exhibited increased suppression after a shift from 32% to 6% sucrose solution (32-->6), relative to 6...
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PMID: 16135386
PDF is available here.
Abstract
Highly palatable food and drugs of abuse share the ability to stimulate dopamine transmission in the shell of the nucleus accumbens. However, while in the case of food this property is adaptively regulated in a negative fashion upon repeated exposure to the reward, no such regulation is operative to...
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PMID: 16129462
PDF is available here.
Abstract
Previous studies have demonstrated that consumption of a low-valued food substance may decrease if access to a high-valued substance will soon be available (negative anticipatory contrast). Research has also demonstrated that responding for a low-valued reinforcer may increase if responding for a hi...
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PMID: 15913919
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Abstract
Numerous studies suggest an essential role for the intermediate (IRt) and parvocellular (PCRt) reticular formation (RF) in consummatory ingestive responses. Although the IRt and PCRt contain a large proportion of neurons with projections to the oromotor nuclei, these areas of the RF...
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PMID: 15912497
PDF is available here.
Abstract
Withdrawal from chronic cocaine reduces extracellular glutamate levels in the nucleus accumbens by decreasing cystine/glutamate exchange (xc-). Activating xc- with N-acetylcysteine restores extracellular glutamate and prevents cocaine-induced drug seeking. It was hypothesized that the activation of...
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PMID: 16000629
PDF is available here.
Abstract
In the present study, rats received amygdala lesions (AMX) on either Postnatal Day 7 (PD 7; immature brain) or PD 21 (almost mature brain), and adult social activity was studied after short-term isolation housing. Sham-operated rats demonstrated increased following and approaching behavior after 7 d...
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PMID: 15998203
PDF is available here.
Abstract
SR141716A impacts on motivational processes in both the appetitive and consummatory phases of feeding behaviour....
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PMID: 15821957
PDF is available here.
Abstract
Taken together, these data suggest that chronic ethanol exposure increases ethanol intake without clearly enhancing its reinforcing value. Furthermore, NPY has a greater impact on the consummatory factors mediating ethanol intake than appetitive factors mediating ethanol seeking....
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PMID: 15834223
PDF is available here.
Abstract
The preoptic area-anterior hypothalamus (POAH) continuum is critical for the integration of environmental, physiological, and behavioral cues associated with reproduction in vertebrates. In the present study, radiofrequency lesions in the POAH abolished sexual behavior in the leopard gecko (Eublepha...
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PMID: 15533318
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Abstract
We investigated the role of estrogens in the activation of an another index of ASB, the female-induced activation of rhythmic cloacal sphincter movements (RCSMs) that are produced in reaction to the visual presentation of a female. Consummatory sexual behavior (CSB) was also assessed by the frequenc...
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PMID: 15518995
PDF is available here.
Abstract
Male sexual behavior in both field and laboratory settings has been studied in birds since the 19th century. Birds are valuable for the investigation of the neuroendocrine mechanisms of sexual behavior, because their behavior can be studied in the context of a large amount of field data, well-define...
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PMID: 15488549
PDF is available here.
Abstract
We again utilized this lesion to assess the importance of these same neurons for the consummatory phase of glucoprivic feeding. To test consummatory responses, milk was infused intraorally through a chronic cheek fistula until rejected. Appetitive responses were tested in the same rats using pellete...
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PMID: 15276785
PDF is available here.
Abstract
Rats shifted from 4% to 32% sucrose displayed successive negative contrast by initiating significantly fewer bouts of licking than control rats maintained on 4% sucrose. No significant increase in dopamine (DA) efflux in the nucleus accumbens (NAc) was observed during consumption of 4% sucrose by ra...
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PMID: 15301614
PDF is available here.
Abstract
We suggest that Fos is associated with the inhibition of sexual behavior following ejaculation in the CVM, and that auditory information arising from the DC and Tz is combined with copulation-related sensory information in the subparafasicular nucleus and projected to the hypothalamus. In addition,...
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PMID: 15051527
PDF is available here.
Abstract
In the present study, the authors examined the effects of diazepam (Valium) on various physical, social, and emotional variables within the framework of a task designed to test risk-taking behavior. Participants received either 10 mg of diazepam or a placebo. After the participants tasted strong-fla...
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PMID: 15088864
PDF is available here.
Abstract
We recorded the firing activity of rat NAc neurons during the performance of a discriminative stimulus task. In this task, the animal must make an operant response to an intermittently presented cue to obtain a sucrose reward delivered in a reward receptacle. Uncued entries to the receptacle were no...
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PMID: 14645378
PDF is available here.
Abstract
These results provide no support for the experimental hypothesis. Rather, the data seem best interpreted as a lesion-induced disruption of the comparison mechanism responsible for anticipatory negative contrast. By this analysis, different comparison mechanisms underlie simultaneous and anticipatory...
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PMID: 15113262
PDF is available here.
Abstract
This report describes the responses of an experienced gorilla mother to inappropriate maternal behavior displayed by her young adult daughter toward a newborn baby and repeated acts of baby-transfer between these two females in a captive social group of lowland gorillas ( Gorilla g. gorilla). The qu...
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PMID: 14586802
PDF is available here.
Abstract
The enhancement of dopamine during transfer into the operant chamber does not depend on anticipation or operant training with ethanol or water reinforcement. Furthermore, the difference between the time course of accumbal dopamine and ethanol in dialysates suggests that the dopamine response is not...
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PMID: 14574227
PDF is available here.
Abstract
We employed a negative incentive contrast procedure to examine whether a decrease of sucrose concentration in a regularly visited flower type affects bumblebee (Bombus impatiens) consummatory or choice behavior. Subjects were trained to enter a test arena where they foraged on a single, red, artific...
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PMID: 12954395
PDF is available here.
Abstract
These results suggest that the Formosan leaf-nosed bats are selective of their roosts, but the pattern of their roost selection differs from those reported for bats of temperate regions. The reasons for such differences may be related to differences in body size, behavior, and reproductive strategy...
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PMID: 12951409
PDF is available here.
Abstract
We measured appetitive sexual behavior by administering behavioral tests in bilevel chambers and quantifying anticipatory level changes during a 5-min period prior to introduction of a stimulus female. In addition, we recorded standard measures of consummatory male sexual behavior after the female w...
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PMID: 13129487
PDF is available here.
Abstract
The ability of Antabuse (disulfiram) to influence ethanol consumption and learning in harnessed honey bees was investigated. In the first series of experiments a factorial design was used with 5 levels of ethanol concentration (0%, 1%, 5%, 10%, 20%), 4 doses of Antabuse (0, 37 microg/g, 3.7 microg/g...
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PMID: 12785614
PDF is available here.
Abstract
Behavioral suppression is observed when animals shift from a high to a lower magnitude of reward in comparison to animals that continuously receive the lower magnitude reward. As previously reported, systemic administration of benzodiazepines promotes recovery from this negative contrast. This study...
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PMID: 12667910
PDF is available here.
Abstract
We investigate the consequences of size-dependent competition among the individuals of a consumer population by analyzing the dynamic properties of a physiologically structured population model. Only 2 size-classes of individuals are distinguished: juveniles and adults. Juveniles and adults both fee...
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PMID: 12464491
PDF is available here.
Abstract
The data support the conclusion that ethanol seeking in the P rat can be influenced by environmental history, whereas consummatory behavior appears to be under more explicit genetic control. This gene-environment interaction suggests that, in the P rat, seeking behavior, initially set at higher leve...
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PMID: 12608490
PDF is available here.
Abstract
Two groups of rats, 'shifted' (32-4% sucrose) and 'unshifted' (4-4% sucrose), were given access to sucrose solutions for 5 min/day for 10 days. On day 11, shifted animals had access to a devalued incentive (4% sucrose) and subgroups of each group received doses of amisulpride (10 or 60 mg/kg, i.p.)...
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PMID: 12478217
PDF is available here.
Abstract
These findings indicate that appetitive and consummatory processes are distinct and that P rats have an increased tendency to both seek and drink ethanol and sucrose solutions, making this selected line useful when modeling both "craving" and "loss of control" related behaviors involved in excessive...
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PMID: 12436053
PDF is available here.
Abstract
The present study set out to establish the chronic mild stress (CMS) animal model of depression in male CD-1 mice, a commonly used mouse strain. Mice were exposed to a series of mild stressors (e.g. soiled bedding, paired housing, cage tilt, white noise) presented in a continuous unpredictable fashi...
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PMID: 12095069
PDF is available here.
Abstract
These results are considered in the context of anatomical projections from these amygdalar areas to other brain regions involved in feeding, and the role of amygdala subregions in the acquisition of motivational value in conditioning....
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PMID: 12175595
PDF is available here.