Abstract
We report that certain Microlepidoptera chemically dissolve pollen grains with exudates from their mouthparts.
Field observations and experiments in tropical China revealed that two species of Deltophora (Gelechioidea) are the exclusive pollinators of two species of Phyllanthus (Phyl...
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PMID: 21552530
PDF is available here.
Abstract
ABSTRACT: Forming synaptic connections of the appropriate strength between specific neurons is crucial for constructing neural circuits to control behavior. A recent paper in Neural Development describes the use of a synapse-specific label in Caenorhabditis elegans to implicate local...
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PMID: 21663686
PDF is available here.
Ying-Chang YC Lu,
Chen-Chi CC Wu,
Wen-Sheng WS Shen,
Ting-Hua TH Yang,
Te-Huei TH Yeh,
Pei-Jer PJ Chen,
I-Shing IS Yu,
Shu-Wha SW Lin,
Jau-Min JM Wong,
Qing Q Chang,
Xi X Lin and
Chuan-Jen CJ Hsu
Abstract
We established a knock-in mouse model (i.e., Slc26a4(tm1Dontuh/tm1Dontuh) mice) homozygous for the c.919-2AG mutation, which is a common mutation in East Asians. Mice were then subjected to audiologic assessment, a battery of vestibular evaluations, and inner ear morphological studies. All Slc26a4(t...
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PMID: 21811566
PDF is available here.
Abstract
We therefore examined memory in arouser (aru) mutant flies, which have recently been identified as having ethanol sensitivity deficits. The aru mutant flies showed memory deficits in both short-term place memory and olfactory memory tests. Flies with a revertant aru allele had wild-type levels of me...
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PMID: 21818402
PDF is available here.
Abstract
These results demonstrate for the first time that the preimplantation embryo in vivo is sensitive to maternal systemic inflammation, with effects on blastocyst cell lineage allocation and consequences for behavior, adiposity and innate immune response in adult offspring. Critically, we identify a no...
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PMID: 21771319
PDF is available here.
Abstract
We look at the relationship between the pattern of brain damage and spatial memory deficits in two chronic models of TLE (lithium-pilocarpine, LIP and kainic acid, KA) from two different rat strains (Wistar and Sprague-Dawley) using the Morris water maze and the elevated plus maze in combination wit...
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PMID: 21829459
PDF is available here.
Abstract
Recent clinical findings support the notion that the progressive deterioration of cholesterol homeostasis is a central player in Alzheimer's disease (AD). Epidemiological studies suggest that high midlife plasma total cholesterol levels are associated with an increased risk of AD. This paper reports...
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PMID: 21829488
PDF is available here.
Abstract
Multichannel single-unit recordings were used to investigate the activity of individual neurons and neuronal ensembles in the rat brain following the application of noxious laser stimuli of increasing intensity to the hindpaw. Four brain regions were monitored, including two within the lateral senso...
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PMID: 21864358
PDF is available here.
Abstract
To explore the effect of Bushen Huoxue Decoction (BHD) on the orphan receptor (Nurr1) and tyrosine hydroxylase (TH) in the brain of rats with Parkinson's disease (PD).
One hundred and twenty SD rats were divided into 100 in the model group and 20 in the normal control...
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PMID: 21258896
PDF is available here.
Abstract
The aim of the present study was to investigate the role of GABAergic and nitriergic modulation in the antianxiety effect of thymoquinone, a major constituent of Nigella sativa, in mice under unstressed and stressed conditions. Thymoquinone (10 and 20 mg/kg), methylene blue (1 mg/kg)...
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PMID: 21857076
PDF is available here.
Ahmad Pazirandeh,
Taranum Sultana,
Momina Mirza,
Björn Rozell,
Kjell Hultenby,
Karin Wallis,
Björn Vennström,
Ben Davis,
Anders Arner,
Rainer Heuchel,
Matthias Löhr,
Lennart Philipson and
Kerstin Sollerbrant
Abstract
We constructed a mouse line in which the CAR gene could be disrupted at any chosen time point in a broad spectrum of cell types and tissues. All knockouts examined displayed a dilated intestinal tract and atrophy of the exocrine pancreas with appearance of tubular complexes characteristic of acinar-...
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PMID: 21674029
PDF is available here.
Abstract
We previously established a mouse model of FM-like pain, induced by intermittent cold stress (ICS).
In this study, we find that ICS exposure causes a transient increase in plasma corticosterone concentration, but not in anxiety or depression-like behaviors. A single intrathecal injec...
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PMID: 21933442
PDF is available here.
Abstract
We manipulated levels of Ena, the Drosophila homologue of Mena, in migrating embryonic macrophages (haemocytes). Consistent with data from fibroblasts in vitro, Ena localises to regions of actin dynamics within migrating haemocytes, stimulates lamellipodial dynamics and positively regulates the numb...
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PMID: 21045209
PDF is available here.
Abstract
We examined interactions among Cordia alliodora myrmecophytic trees, their symbiotic ants Azteca pittieri, coccoid hemipterans, and foliar herbivores in two Neotropical dry forests. The tree makes two investments in symbiotic ants: it supplies nesting space, as domatia, and it provides phloem to coc...
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PMID: 21560674
PDF is available here.
Abstract
The purpose of the study was to evaluate the kinematic characteristics of pelvic limb joints in orthopaedically normal dogs during stair ascent.
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PMID: 21243173
PDF is available here.
Abstract
We review the body of evidence investigating the relationship between hippocampal neurogenesis and learning to conclude the functional role of adult-born hippocampal neurons. First, factors that could explain discrepancies among experiments are taken into account. Then, in addition to methodological...
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PMID: 21591906
PDF is available here.
Abstract
We tested the sensory and motor recovery of the sciatic nerve with Hargreaves method, using an apparatus from Ugo Basile, Italy. Testing was continued for both legs of each rat, injured and uninjured, starting preoperatively (0 day), and then 1, 7, 14, 21, and 28 days postoperatively. The same exper...
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PMID: 21648317
PDF is available here.
Abstract
We will focus this review on three main aspects; first of all, the impact of Bdnf polymorphism on fear related characteristics in humans and animal models. Secondly, we will discuss BDNF-TrkB activity regulation by epigenetic, transcriptional and post-translational events, and finally we will discus...
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PMID: 21639804
PDF is available here.
Abstract
We tested Xybrex (Orthocon, Inc., Irvington, NY), a slow-release formulation of lidocaine that blocks rat sciatic nerve for 1-2 days, for its ability to suppress postincisional pain.
A plantar paw incision was made in rats, either along the midline (Brennan model) or at the lateral edge, 30 min afte...
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PMID: 21169797
PDF is available here.
Abstract
We presented an overview of the current literature in which the effects of radioactive pollutants on behavior in humans, rodents, fish and wildlife species are addressed. When possible, we have also indicated the potential underlying mechanisms of the behavioral alterations and parameters measured....
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PMID: 21170702
PDF is available here.
Abstract
Our previous study revealed that centrally acting non-narcotic antitussives inhibited G-protein-coupled inwardly rectifying K(+) (GIRK) channel currents in brain neurons, and that the tipepidine antitussives had a novel antidepressive-like effect on rats. Furthermore, the antitussives revealed multi...
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PMID: 20713091
PDF is available here.
Abstract
We found no ecotoxicological effects of wastewater ozonation on invertebrates (n=82), but significant adverse effects on bacteria (n=24) and fish (n=5). As information on functional endpoints or trophic interactions is lacking, we applied a bioassay relating to leaf litter decomposition to fill this...
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PMID: 21044796
PDF is available here.
Abstract
We tested for heterosis in a cross of two replicate lines of mice selectively bred for high voluntary wheel running for 53 generations. Mice were paired to produce four sets of F1 offspring: two purebred High Runner (HR) lines and the hybrid reciprocal crosses. The purebred HR showed statistically s...
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PMID: 21184162
PDF is available here.