Abstract
We conducted a 24-week, rater-blinded, flexible-dose study. Sixty patients with DSM-IV schizophrenia (n = 58) or schizoaffective disorder (n = 2) met the DSM-IV research criteria for neuroleptic-induced tardive dyskinesia and were randomly assigned to a risperidone or olanzapine group. The p...
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PMID: 20441726
PDF is available here.
Abstract
We distinguish between productivity, work role limitations, quality of work output, and extra effort required to remain productive.
Two systematic literature studies; the first to identify articles that measured work functioning in workers with CMDs, and the second to identify work functioning measu...
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PMID: 20657300
PDF is available here.
Abstract
Three quarter presented with at least two predisposing factors, the commonest being family issues (42%), relationship problems (40%) and general military stress (39%). Up to half of young male Soldiers required a MH assessment as a result of wanting to leave the Army, and were positively associated...
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PMID: 20648944
PDF is available here.
Abstract
The ABC is the first self-report that measures patient expectations about the benefits of treatment on everyday functioning, filling an important gap in available assessments of attitudes and expectations about treatment. The ABC is simple, easy to use, and has acceptable psychometric properties for...
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PMID: 19785919
PDF is available here.
Abstract
Follow-up information was collected on up to 90.0% (n = 651) of the baseline cohort of 723 participants, with 66.9% (n = 484) interviewed. In the last 2 years, 57% of individuals with schizophrenia/schizophreniform, 54% with schizoaffective disorder, 62% with affective psychosis, and 68% with other...
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PMID: 20573330
PDF is available here.
Abstract
All the sample of patients showed a significant improvement in symptomatology during hospitalization. Worse symptomatology in anxiety-depression domain of BPRS at admission in the whole sample was positively correlated with length of stay. A longer length of stay was also shown in patients with diag...
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PMID: 19585061
PDF is available here.
Abstract
The findings supported the direct effects of self-stigma on reducing psychosocial treatment adherence, and its indirect influences mediated by insight and stages of change on treatment adherence. Psychopathology was also found to have a direct effect on undermining adherence. This model showed bette...
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PMID: 19649752
PDF is available here.
Abstract
Patients with stroke with insomnia showed poor sleep patterns. Active management improved sleep patterns and helped such patients achieve functional and cognitive outcomes equivalent to those attained by patients without insomnia....
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PMID: 20068430
PDF is available here.
Abstract
The prevalence of smoking is high in persons with serious mental illness (SMI) despite associated health risks. Persons with SMI die on average 25 years earlier than the general population and an increased focus on wellness, including smoking cessation, has been a goal of federal, st...
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PMID: 20511731
PDF is available here.
Abstract
These data confirm that an accurate psychological screening can be extremely useful to support the Psychologist working in cardiac rehabilitation as it helps to plan more specifically the interventions, focusing on the objective patients' educational and psychological needs....
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PMID: 20925173
PDF is available here.
Abstract
The role of confrontation in recovery has been vigorously debated. Proponents suggest confrontation can break down denial and increase motivation. Critics point to counseling studies showing confrontation harms the therapeutic alliance and increases resistance. Frequently missing in these debates is...
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PMID: 20464806
PDF is available here.
Abstract
Our results suggest a minor contribution to antipsychotic drug response of genetic alterations in the 5-HTT gene.
2009 Elsevier B.V. All rights reserved....
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PMID: 20031235
PDF is available here.
Abstract
These results indicate that the major factors associated with occupational stress differed between male and female doctors in China. Overall, role boundary and role insufficient were the most crucial factors in male and female doctors, respectively. Therefore, occupational health education and occup...
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PMID: 19701645
PDF is available here.
Abstract
People with schizophrenia consistently report normal levels of pleasant emotion when exposed to evocative stimuli, suggesting intact consummatory pleasure. However, little is known about the neural correlates and time course of emotion in schizophrenia. This study used a well-validated affective pic...
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PMID: 20141239
PDF is available here.
Abstract
Patients who did not respond to clozapine had significantly lower total BPRS scores (P = .01) at baseline, driven primarily by lower ratings in hostility (P = .007) and activation (P = .02), compared with those who responded to clozapine. Responders and nonresponders did not differ in their age, rac...
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PMID: 20399340
PDF is available here.
Abstract
AIM: Objectives were to identify syndromes measured by BPRS-E scale and to analyse changes in syndromes' consistency in the course of a 12 year prospective study. METHOD: A group of 80 patients with diagnosis of schizophrenia was followed up in 1, 3, 7 and 12 years after their first psychiatric hosp...
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PMID: 20677438
PDF is available here.
Abstract
Our data suggest no association between investigated alleles and genotypes in FAT and response to aripiprazole. However, because several limitations characterize the present study, further investigations on larger studies are required....
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PMID: 19893579
PDF is available here.
Abstract
We used a retrospective case control study design; 926 subjects who were aged > or = 77 years at Wave 3 were examined. MMSE scores were utilized to predict falls two years later. Measurements included sociodemographic characteristics, MMSE scores, activities of daily living (ADL), instrumental activ...
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PMID: 20178182
PDF is available here.
Abstract
Sensory rooms and the use of multisensory interventions are becoming popular in inpatient psychiatry. The empirical data supporting their use are limited, and there is only anecdotal evidence indicating effectiveness in psychiatric populations. The specific aims of this observational pilot study wer...
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PMID: 20102130
PDF is available here.
Abstract
: There was sufficient evidence of internal consistency (Cronbach alpha = .87), which supported the reliability of the BSI. There was evidence of criterion-related validity based on the Spearman rho correlation coefficient of 0.70 (P < .001) between BSI and SAI scores. Anxious patients had higher com...
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PMID: 20168191
PDF is available here.
Abstract
Impaired performance of siblings on facial emotion identification and discrimination tasks provides evidence for the hypothesis that facial emotion recognition deficits are transmitted in families and may represent a heritable endophenotype of schizophrenia....
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PMID: 20092378
PDF is available here.
Abstract
Treatment with clozapine was associated with greater odds of a pay increase (OR = 3.13; 95% CI 1.3 to 7.53, P = 0.01). However, patients on other antipsychotics had a more favourable improvement in BPRS (F = 5.44, df = 1,57, P = 0.02). Patients on other antipsychotics also had a higher count of post...
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PMID: 20113544
PDF is available here.
Abstract
We investigated the impact of a 15-month treatment with the AChE inhibitor donepezil on blood levels of the HGFs stem cell factor (SCF), stromal cell-derived factor 1 (SDF-1), granulocyte colony- stimulating factor (G-CSF) and vascular endothelial growth factor (VEGF) in 19 patients with AD and 45 a...
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PMID: 19580698
PDF is available here.
David de Lucena,
Brisa Simões Fernandes,
Michael Berk,
Seetal Dodd,
Dalton W Medeiros,
Mariana Pedrini,
Mauricio Kunz,
Fabiano Alves Gomes,
Larriany F Giglio,
Maria Inês Lobato,
Paulo Silva Belmonte-de-Abreu and
Clarissa Severino Gama
Abstract
Memantine add-on to clozapine therapy was associated with improvement in negative and positive symptoms in refractory schizophrenia patients. TRIAL REGISTRATION: clinicaltrials.gov Identifier: NCT00757978.
Copyright 2009 Physicians Postgraduate Press, Inc....
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PMID: 19906345
PDF is available here.
Abstract
Participants taking prazosin (mean dose: 5.7 +/- 0.9 mg/day) had greater improvements than those taking placebo (mean dose: 5.6 +/- 1.2 mg/day) on the NPI (mean change: -19 +/- 21 versus -2 +/- 15, chi = 6.32, df = 1, p = 0.012) and BPRS (mean change: -9 +/- 9 versus -3 +/- 5, chi = 4.42, df = 1, p...
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PMID: 19700947
PDF is available here.
Abstract
There is little research in Brazil on cognition and menopause, despite the high frequency of neuropsychiatric complaints in this phase of women's life. The authors present a cross-sectional study aimed at describing the scores by 156 menopausal women on the Mini-Mental State Examination (MMSE) and t...
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PMID: 19750376
PDF is available here.
Abstract
We review evidence regarding the anti-inflammatory actions of mood-stabilizing medication, the putative reciprocal association of inflammation with behavioral parameters and medical burden in bipolar disorder, and the potential role of anti-inflammatory agents in the treatment of bipolar disorder. D...
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PMID: 19497250
PDF is available here.
Abstract
Antipsychotics are often the first line of treatment for individuals with schizophrenia (). One challenge to effective treatment is lack of adherence to prescribed medication. Lower rates of adherence are associated with considerably higher rates of relapse and poorer course of illness. Therefore st...
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PMID: 19684494
PDF is available here.
Abstract
The rates of the major dementias were similar in the younger-, older-, and oldest-old groups except for the higher rate of FTLD and the lower rate of DLB, respectively, in the younger-old patients. The cognitive and overall dementia severity status of the oldest-old patients with AD referred to the...
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PMID: 19697887
PDF is available here.
Abstract
Overall, 21 patients (21.2%) were categorised as having 'good' and 36 (36.4%) as having 'poor' subjective QOL. 'Poor' subjective QOL correlated with anxiety/depression symptoms (OR 4.88, 95% CI 2.93-11.48), comorbid medical problems (OR 4.75, 95% CI 1.43-16.33), unemployment (OR 3.75, 95% CI 1.25-11...
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PMID: 19416124
PDF is available here.
Abstract
Origins of impaired adaptive functioning in schizophrenia remain poorly understood. Behavioral disorganization may arise from an abnormal reliance on common combinations between concepts stored in semantic memory. Avolition-apathy may be related to deficits in using goal-related requ...
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PMID: 19413402
PDF is available here.
Abstract
We identified few successful cases of switches from clozapine in our search of the literature. Although controlled clinical trial data support use of clozapine in treatment-refractory schizophrenia, some patients cannot tolerate this agent or it may increase the risk of physical problems for some pa...
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PMID: 19461396
PDF is available here.