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Mental Status Schedule (0):
Recent article
Mental Status Schedule
Abstract
We performed biochemical characterization and quantification of TDP-43 in homogenates from parietal neocortex of subjects with aclinical diagnosis of no cognitive impairment (NCI, n = 12), mild cognitive impairment (MCI, n = 12), or AD (n = 12). Immunoblots revealed increased detergent-insoluble TDP...
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PMID: 21865887
PDF is available here.
PDF is available here.
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Abstract
To track cognitive change over time in dementia-free older adults and to examine terminal cognitive decline.
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PMID: 21832224
PDF is available here.
PDF is available here.
Psychiatry Research (188)3 2011
Abstract
These results provide insights into the relations among childhood traumatic events, substance use, and clinical features of first-episode psychosis, creating hypotheses for future research.
Copyright © 2011 Elsevier Ltd. All rights reserved....
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PMID: 21665293
PDF is available here.
PDF is available here.
Psychiatry Research (192)3 2011
Abstract
We hypothesized that the frontal lobe associated with social interaction was being stimulated. To test this hypothesis, we studied 24 patients with vascular dementia. In addition to conventional care, a 1-h session of GRA with RO was provided once a week for 3 months in the GRA-RO arm (n=12). Only s...
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PMID: 21543189
PDF is available here.
PDF is available here.
Acta Neurologica Belgica (111)1 2011
Abstract
The aim of the present study was to evaluate pain perception and evoked responses by laser stimuli (LEPs) in mild not demented Huntington's Disease (HD) patients. Twenty-eight HD patients and 30 control subjects were selected. LEPs were obtained by four scalp electrodes, (Fz, Cz, referred to the nasi...
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PMID: 21510231
PDF is available here.
PDF is available here.
Abstract
We have previously reported the specific increase of leucine-rich alpha-2-glycoprotein (LRG) in iNPH CSF, and the present study investigates its potential clinical applications....
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PMID: 21336807
PDF is available here.
PDF is available here.
Abstract
Normal-pressure hydrocephalus (NPH) is characterized by gait disturbance, cognitive impairment, with or without urinary incontinence, enlarged ventricles with or without cerebral atrophy and normal cerebrospinal fluid pressure.
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PMID: 21320833
PDF is available here.
PDF is available here.
Abstract
We performed a retrospective review of the Negative Emotion subscale (NES) score, a measure of psychological health within the ALS-Specific QoL Instrument. Analysis of 72 patients over three months, and of a subset of 48 over six months, showed stability of psychological health despite a decline in...
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PMID: 21294667
PDF is available here.
PDF is available here.
Abstract
We observed age-related declines in new forms (illusory percepts) but merely a trend in the same direction for transitions (changes from the veridical sensory experience to illusory percepts and reversals to either the veridical sensory experience or other percepts). There was no evidence that parti...
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PMID: 21506453
PDF is available here.
PDF is available here.
Journal of Clinical Psychiatry (71)suppl 2 2010
Abstract
To make an accurate differential diagnosis of schizoaffective disorder, clinicians can carefully gather information from patients and other informants, consider the information within a conceptual diagnostic framework, differentiate between schizoaffective disorder and other disorders, and reevaluat...
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PMID: 21190646
PDF is available here.
PDF is available here.
Abstract
We examined the main effects of family history and APOE varepsilon4 on brain integrity, in addition to assessing possible additive effects of these two risk factors.
Diffusion tensor imaging was performed in 136 middle-aged asymptomatic participants stratified on family history and A...
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PMID: 20713315
PDF is available here.
PDF is available here.
Abstract
Out of the 6 expected genotypes, only 5 were detected in participants: E3/3 (56.0%), E3/4 (23.6%), E4/4 (8.2%), E2/4 (3.3%), E2/3 (8.9%). The ε3 allele (72%) was the most frequent, followed by ε4 (22%) and ε2 (6%). No difference was found in plasma levels of either apoE or in apoE genotype freque...
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PMID: 20455863
PDF is available here.
PDF is available here.
Abstract
We present normative data from a large population-based sample of centenarians for several brief, global neurocognitive tasks amenable for frail elders. Comparative data from octogenarians are included. A total of 244 centenarians and 80 octogenarians from Phase III of the Georgia Centenarian Study...
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PMID: 20521181
PDF is available here.
PDF is available here.
Brain research (1349) 2010
Abstract
We examined 3,061 community residents aged 65 years or older who had a score of 24 or more on the Mini-Mental State Examination. The subjects were divided according to their score for the three-word delayed recall test into control (score: 3 or 2) and MMI (score: 1 or 0) subjects. The subjects under...
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PMID: 20599812
PDF is available here.
PDF is available here.
Journal of the Neurological Sciences (295)1-2 2010
Abstract
We have investigated it in 212 sporadic LOAD patients and 203 healthy controls from Chinese. No significantly increased risk of LOAD in the carriers of XRCC1 194Trp allele (OR=1.04, 95% CI 0.70-1.52, P=0.860) was observed. As expected, Apolipoprotein (APOE) epsilon4 allele significantly increased th...
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PMID: 20553853
PDF is available here.
PDF is available here.
Abstract
CONTEXT: Delirium occurs in many hospitalized older patients and has serious consequences including increased risk for death and admission to long-term care. Despite its importance, health care clinicians often fail to recognize delirium. Simple bedside instruments may lead to improv...
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PMID: 20716741
PDF is available here.
PDF is available here.
Abstract
The cut-off of SIS score was <2 for illiterate, <3 for elementary, and <4 for junior high school or above. The sensitivity and specificity of SIS for detecting mild AD were 88.5% and 78.3%, respectively, with an overall accuracy of 83.8%, while for detecting MCI, the sensitivity and specificity were...
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PMID: 20651813
PDF is available here.
PDF is available here.
Abstract
The subjects with no errors in the SPMSQ test (32%) consumed greater quantities of cereals, eggs, oils, and fats. After adjusting for energy intake and educational level an inverse association was seen between fish and vegetable consumption and cognitive capacity score. In addition, these subjects h...
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PMID: 20013126
PDF is available here.
PDF is available here.
Abstract
We investigated morphological asymmetry in 653 consecutive autopsy patients from a general geriatric hospital (age [mean +/- SD] = 81.1 +/- 8.9 years), focusing on those from patients with advanced argyrophilic grain disease. Paraffin sections of the bilateral posterior hippocampi were immunostained...
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PMID: 20535032
PDF is available here.
PDF is available here.
Abstract
Abstract
We investigated whether similar impairment rates were observed between the Hopkins Verbal Learning Test-Revised (HVLT-R) and Logical Memory (LM) in 90 patients with amnestic or amnestic plus MCI. On HVLT-R delayed recall, 80% of participants performed in the MCI range compared to only 32.2% on LM II...
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PMID: 20603742
PDF is available here.
PDF is available here.
Abstract
To validate the Neuropsychological Assessment Battery (NAB) List Learning test as a predictor of future multi-domain cognitive decline and conversion to Alzheimer's disease (AD), participants from a longitudinal research registry at a national AD Center were, at baseline, assigned to one of three gr...
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PMID: 20374677
PDF is available here.
PDF is available here.
Psychiatry Research (182)3 2010
Abstract
We report the case of a 51-year-old woman who was admitted at a Psychiatric Day Hospital presenting with depressive symptoms, visuospatial deficits, apraxia, and minor memory loss. The patient underwent long-term antidepressant therapy, but despite the improvement of depressive symptoms, there was p...
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PMID: 20488678
PDF is available here.
PDF is available here.
Psychiatry Research (182)3 2010
Abstract
We correlated clinical scores of behavioral and executive deficits with glucose utilization as measured by [(18)F]fluorodeoxyglucose positron emission tomography in 17 patients with frontotemporal lobar degeneration and 9 age- and sex-matched control subjects. Impairment in executive functions was m...
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PMID: 20493673
PDF is available here.
PDF is available here.
Psychiatria Danubina (22)2 2010
Abstract
Degeneration of cholinergic receptors causes memory disorders and irreversible impairment in cognitive functions, whose advancement can lead to clinically recognizable Alzheimer's disease (AD). Very often, the first symptoms of AD are mood swings and hence depression should be excluded by differenti...
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PMID: 20562790
PDF is available here.
PDF is available here.
Psychiatria Danubina (22)2 2010
Social behaviour vs. psychiatric features of frontotemporal dementia - Clinical report of two cases.
Abstract
We report two individuals who met current clinical criteria for behavioural or frontal variant FTD (bv-FTD), with the aim of distinguishing between psychotic symptoms and the often bizarre personality and behaviour change found in FTD. Also we review the literature on the noncognitive neuropsyhiatri...
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PMID: 20562743
PDF is available here.
PDF is available here.
Psychiatria Danubina (22)2 2010
Abstract
The graph of MMSE scores illustrates severe decline in scores, followed eventually by increase in score to sustained improvement while continuing on galantamine. Functionally, this lady has successfully negotiated a divorce, moved into her own accommodation, began travelling on holidays, including a...
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PMID: 20562785
PDF is available here.
PDF is available here.
Schizophrenia Research (119)1-3 2010
Abstract
Throughout the study, patients treated with glycopyrrolate or biperiden had significantly reduced DRS scores. Moreover, the DRS scores were significantly lower with glycopyrrolate treatment than with biperiden. In other respects, there were no significant differences in MMSE scores in patients treat...
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PMID: 20299191
PDF is available here.
PDF is available here.
Psychological Medicine (40)6 2010
A prospective study of diurnal cortisol and cognitive function in community-dwelling elderly people.
Abstract
HPA axis dysregulation seems to be associated with low cognitive performance in the elderly. Slower cortisol elimination rates could predict cognitive decline affecting principally non-verbal functioning in men and verbal functioning in women. The effects are independent of environmental context, ap...
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PMID: 19814852
PDF is available here.
PDF is available here.
Ugeskrift for laeger (172)20 2010
Abstract
A total of 142 patients were screened, among whom 100 were included (81 women and 19 men). The mean age was 83.9 years (range: 65-101 years). Background parameters: constipation 29%, urinary incontinence 41%, bacteriuria 37%. Barthel (maximum score 100): 12% score < 26, 25% score 26-49, 41% score 50...
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PMID: 20483097
PDF is available here.
PDF is available here.
Ugeskrift for laeger (172)20 2010
Abstract
The elderly population of ethnic minorities is increasing in most Western countries, but ethnic minority patients are underrepresented in dementia assessment and care. This may in part be due to cultural perceptions of dementia and lack of knowledge about the available support among ethnic minoritie...
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PMID: 20483100
PDF is available here.
PDF is available here.
Abstract
We determined the pattern of cortical metabolism that was associated with visuo-constructive performance in AD. We employed two widely used visuo-constructive tests that differ in their demand on visual perception and processing capacity. Resting state FDG-PET scans were obtained in 29 probable AD p...
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PMID: 19875130
PDF is available here.
PDF is available here.
Neuropsychologia (48)6 2010
Abstract
Our results add to existing literature and illustrate the very nature of deficits of mentalizing, measured by a faux pas test, experienced by people with medial frontal lesions. The data have also prompted that future behavioral and neuroimaging studies may be applied to further decode both the neur...
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PMID: 20156464
PDF is available here.
PDF is available here.
Psychiatrische Praxis (37)4 2010
Abstract
Patients treated by outpatient clinics at psychiatric hospitals suffered from more severe neuropsychiatric symptoms (p < 0.05), were prescribed more antidepressants and antidementia agents (p < 0.05) and, when adjusting for the severity of agitation, less neuroleptics (p < 0.05) as compared to prima...
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PMID: 20225175
PDF is available here.
PDF is available here.
Abstract
A score of less than 40 in the abridged version of the Cross-Cultural Cognitive Examination was independently correlated with an increase in mortality within the next two years....
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PMID: 20602071
PDF is available here.
PDF is available here.
CNS Spectrums (15)5 2010
Abstract
The mean age of the subjects was 53.6 years (SD=15.8), 65% were female, and mean HRSD(24) was 33.9 (SD=6.7). Mean demographic-corrected T-scores for each neurocognitive measure were in the average to borderline range, and HRSD(24) values were unrelated to performance on the MMSE, RAVLT immediate and...
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PMID: 20448521
PDF is available here.
PDF is available here.
Abstract
We discuss the results in terms of the utility of these measures as potential indicators of cognitive impairment....
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PMID: 20480679
PDF is available here.
PDF is available here.
Perceptual and Motor Skills (110)2 2010
Abstract
Qualitative analysis of item content conducted on two versions of mental status examinations indicated that the Modified Mini-Mental State examination is a more pragmatic screening device to use not only for early detection of dementia but also as a basis for developing individualized care planning...
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PMID: 20499546
PDF is available here.
PDF is available here.
Abstract
We examined drug effects cross-sectionally at baseline, 6 months, and 12 months. There were no significant differences in efficacy among the three AEDs. LEV caused fewer adverse events than the other AEDs. PB produced persistent negative cognitive side effects. LEV was associated with improved cogni...
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PMID: 20188634
PDF is available here.
PDF is available here.
Abstract
We were able to distinguish patients with mild DLB from those with AD with a high level of accuracy. Our findings suggest that combining MR imaging and SPECT modalities is a useful and practical approach for diagnostically differentiating DLB from AD....
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PMID: 20075101
PDF is available here.
PDF is available here.
Abstract
The computer self test (CST) is an interactive, internet-based instrument designed to assess functional cognitive domains impaired by Alzheimer's disease (AD) and mild cognitive impairment (MCI). This study consisted of 215 total subjects with a mean age of 75.24. The 84 cognitively impaired patient...
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PMID: 20164591
PDF is available here.
PDF is available here.
Abstract
We investigated whether hallucinations in AD were associated with greater treatment benefits with rivastigmine. Data were pooled from two randomized, double-blind, 6-month, mild-to-moderate AD trials comparing rivastigmine with placebo. Co-primary efficacy parameters were the Alzheimer Disease Asses...
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PMID: 20164585
PDF is available here.
PDF is available here.
Neuroreport (21)4 2010
Abstract
Multiple regression voxel-based morphometry analyses were used to examine the relationship between regional gray matter volumes and neurocognitive performance in 10 patients with amnestic mild cognitive impairment and 20 healthy age-matched controls. Cognitive functioning was assessed with seven sta...
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PMID: 20042900
PDF is available here.
PDF is available here.
Abstract
Abstract
In this study, the lengthy NPA chosen introduced a statistically and clinically significant source of selection bias. These results highlight the importance of selecting brief and well tolerated assessments when possible. However, researchers are challenged by weighing the improved selection bias as...
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PMID: 20437940
PDF is available here.
PDF is available here.
Psychiatrische Praxis (37)2 2010
Abstract
MMSE scores may in fact be used for dementia survival prognoses in counseling family and professional caregivers of dementia patients, but also for socioeconomic management of the increasing dementia burden for society....
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PMID: 20183772
PDF is available here.
PDF is available here.
Abstract
We explored the association of Alzheimer's disease (AD) Assessment Scale (ADAS-Cog) item scores with AD severity using cross-sectional and longitudinal data from the same study. Post hoc analyses were performed using placebo data from a 12-month trial of patients with mild-to-moderate AD (N =281 ran...
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PMID: 19949163
PDF is available here.
PDF is available here.
Abstract
We explored the association of Alzheimer's disease (AD) Assessment Scale (ADAS-Cog) item scores with AD severity using cross-sectional and longitudinal data from the same study. Post hoc analyses were performed using placebo data from a 12-month trial of patients with mild-to-moderate AD (N =281 ran...
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PMID: 19949163
PDF is available here.
PDF is available here.
Abstract
Disease-specific assessments are not currently available for patients with Parkinson's disease dementia (PDD). This study evaluated the criterion-related validity and test-retest reliability of the Alzheimer's Disease Assessment scale cognitive subscale (ADAS-cog) in terms of sensiti...
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PMID: 19359706
PDF is available here.
PDF is available here.
Abstract
Disease-specific assessments are not currently available for patients with Parkinson's disease dementia (PDD). This study evaluated the criterion-related validity and test-retest reliability of the Alzheimer's Disease Assessment scale cognitive subscale (ADAS-cog) in terms of sensiti...
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PMID: 19359706
PDF is available here.
PDF is available here.
Abstract
Disease-specific assessments are not currently available for patients with Parkinson's disease dementia (PDD). This study evaluated the criterion-related validity and test-retest reliability of the Alzheimer's Disease Assessment scale cognitive subscale (ADAS-cog) in terms of sensiti...
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PMID: 19359706
PDF is available here.
PDF is available here.
Abstract
Wandering is a complex behavior, and defining wandering has been challenging. The current study used the integrated circuit (IC) tag monitoring system to describe the distance moved per day and the spatial movements of patients with dementia. The study was conducted in a 60-bed semia...
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PMID: 20107237
PDF is available here.
PDF is available here.
Abstract
Wandering is a complex behavior, and defining wandering has been challenging. The current study used the integrated circuit (IC) tag monitoring system to describe the distance moved per day and the spatial movements of patients with dementia. The study was conducted in a 60-bed semia...
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PMID: 20107237
PDF is available here.
PDF is available here.
Abstract
Wandering is a complex behavior, and defining wandering has been challenging. The current study used the integrated circuit (IC) tag monitoring system to describe the distance moved per day and the spatial movements of patients with dementia. The study was conducted in a 60-bed semia...
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PMID: 20107237
PDF is available here.
PDF is available here.
Abstract
Despite a dramatic growth of Asian communities in North America, the cultural norms, values, and practices of Asians are generally unknown in the professional community, posing a significant challenge in diagnosis and treatment of mental health problems. This article addresses the major mental healt...
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PMID: 20391230
PDF is available here.
PDF is available here.
Psychology and Aging (25)1 2010
Abstract
We examined instructed and spontaneous emotion regulation in patients with frontotemporal lobar degeneration (FTLD, N = 32), which presents with profound emotional and personality changes; patients with Alzheimer's disease (AD, N = 17), which presents with profound memory impairment; and neurologica...
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PMID: 20230125
PDF is available here.
PDF is available here.
Psychology and Aging (25)1 2010
Abstract
We investigated emotion perception skills involved in decoding facial expressions of emotion in healthy older adults, compared with those with Alzheimer's disease (AD) or late-life mood disorder (MD). Although those with MD were mildly impaired in identifying emotional expressions, this was not caus...
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PMID: 20230126
PDF is available here.
PDF is available here.
Psychology and Aging (25)1 2010
Abstract
We report findings from an intervention study that investigates the impact of group reminiscence (GR) and individual reminiscence (IR) activities on older adults living in care settings. This research aimed to provide a theory-driven evaluation of reminiscence based on a social identity framework. T...
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PMID: 20230136
PDF is available here.
PDF is available here.
Abstract
We investigated oxidative stress in human postmortem frontal cortexfrom individuals characterized as mild cognitive impairment (n= 8), mild/moderate Alzheimer disease (n = 4), and late-stage Alzheimer disease (n = 9). Samples from subjects with no cognitive impairment (n = 10) that were age- and post...
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PMID: 20084018
PDF is available here.
PDF is available here.