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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Biological Factors (10):
Recent article
Biological Factors
Abstract
We investigated whether similar mechanisms occurred in smaller mesenteric resistance arteries from aged Wistar-Kyoto (WKY) rats, spontaneously hypertensive rats (SHRs), and SHRs treated with the angiotensin-converting enzyme inhibitor, enalapril, using immunohistochemistry, serial-section electron m...
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PMID: 19411610
PDF is available here.
PDF is available here.
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Abstract
A general approach to the tetracyclic core of the neomangicol natural products via a late-stage indene alkylation reaction is presented. This strategy sets the stage for access to the neomangicol family and, in addition, provides a potential biogenetically inspired entry to the mangicol natural prod...
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PMID: 19527042
PDF is available here.
PDF is available here.
Abstract
Five extracts from culture liquid of Hypoxylon perforatum showed antifungal activities to Sphaeropsis sapinea growth and germination. CONCLUSION: Ethyl acetate-extract from culture liquid of Hypoxylon perforatum has a highly antifungal activity to Sphaeropsis sapinea, high stability in the natural e...
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PMID: 19873755
PDF is available here.
PDF is available here.
Abstract
Lyophilizing frozen pellets, and especially spray freeze-drying, have been receiving growing interest. To design efficient and safe freeze-drying cycles, local temperature and moisture content in the product bed have to be known, but both are difficult to measure in the industry. Mathematical modeli...
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PMID: 19640137
PDF is available here.
PDF is available here.
European Journal of Pharmacology (614)1-3 2009
Abstract
We have previously shown that plasma levels of ascorbate induce constriction and blockade of dilatation mediated by endothelium-derived hyperpolarizing factor (EDHF). In this study we sought to determine if these detrimental actions were mediated by a prooxidant action of ascorbate. Since trace leve...
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PMID: 19394330
PDF is available here.
PDF is available here.
[Isolation, identification and anticancer activity of an endophytic fungi from Juglans mandshurica].
Abstract
The endophytic fungus named FSN006 was isolated from the inner bark of Juglans mandshurica. It grew quickly and formed circular colony on PDA plate. The upper side of the colony was white, while the lower side of the colony and the conditioned medium were light yellow as a result of significant yell...
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PMID: 19873766
PDF is available here.
PDF is available here.
Biofouling (25)4 2009
Abstract
These results provide new insights into the chemical properties of the undisturbed barnacle adhesive interface....
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PMID: 19263278
PDF is available here.
PDF is available here.
Ginekologia polska (80)5 2009
Abstract
1. The synthesis of leptin depends on body mass, not the duration of pregnancy. 2. Obesity in pregnancy is connected with decreased VEGF synthesis....
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PMID: 19548452
PDF is available here.
PDF is available here.
Circulation (119)17 2009
Abstract
Our study demonstrates that endothelial SK3 and IK1 channels have distinct stimulus-dependent functions, are major players in the EDHF pathway, and significantly contribute to arterial blood pressure regulation. Endothelial K(Ca) channels may represent novel therapeutic targets for the treatment of...
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PMID: 19380617
PDF is available here.
PDF is available here.
Abstract
The elaboration of a 6,6-spiroacetal scaffold to incorporate a nucleoside unit at the anomeric position is described. The novel spiroacetal-nucleoside hybrids were generated via nucleosidation of acetoxy-spiroacetal with a series of silylated nucleobases under Vorbrüggen conditions.
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PMID: 19300829
PDF is available here.
PDF is available here.
Natural Product Reports (26)3 2009
Abstract
Nature abounds with a great number of natural products containing five-membered heterocyclic subunits, such as imidazoles, oxazoles and thiazoles, and their corresponding saturated imidazolines, oxazolines and thiazolines. These naturally occurring metabolites often exhibit pharmacologically importa...
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PMID: 19240947
PDF is available here.
PDF is available here.
Natural Product Reports (26)3 2009
Abstract
This review describes secondary metabolites that have been shown to be synthesized by symbiotic bacteria, or for which this possibility has been discussed. It includes 365 references.
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PMID: 19240945
PDF is available here.
PDF is available here.
Abstract
We have reviewed the role of nitric oxide (NO) and angiotensin II receptors in the modulation of arterial stiffness in the setting of insulin resistance. There is emerging evidence that early stages of INSR may be characterized by increased basal nitric oxide activity and increased activity of non-N...
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PMID: 19436651
PDF is available here.
PDF is available here.
Abstract
Building a better library: The synthesis of a library of natural-product-like small molecules with unprecedented scaffold diversity has been reported (see scheme; Ns = nosylate). The library represents a significant advancement in the capability of synthetic chemists to generate structurally diverse...
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PMID: 19137520
PDF is available here.
PDF is available here.
Marine Drugs (7)4 2009
Abstract
In spite of the high abundance and species diversity of diatoms, only a few bioactive compounds from them have been described. The present study reveals a high number of mammalian cell death inducing substances in biofilm-associated diatoms sampled from the intertidal zone. Extracts from the genera...
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PMID: 20098602
PDF is available here.
PDF is available here.
Dermatology (219)3 2009
Abstract
A response was obtained in 16/17 patients (91.1%) with increased CD25(bright)FOXP3+ values and in only 3/11 patients (27.3%) who showed a CD25(bright)FOXP3+ decrease during biological treatment (p = 0.0001). Responders showed significantly higher values than did non-responders as from the first 2 mo...
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PMID: 19752528
PDF is available here.
PDF is available here.
Abstract
Our data indicate that the EDHF response in mice is caused by hydrogen peroxide, but not by P450 eicosanoids. Moreover, P450 eicosanoids are vasodilatory, largely through their ability to activate endothelial NO synthase (eNOS) and NO release....
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PMID: 18927469
PDF is available here.
PDF is available here.
Abstract
These results conclude that XN-E possesses the most potent antioxidant and antiradical activities, and that these activities could be derived from its high polyphenol content, but not the level of polysaccharides....
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PMID: 19655417
PDF is available here.
PDF is available here.
Abstract
We investigated whether sphingosine kinase, the enzyme responsible for S1P synthesis, plays a role in muscarinic receptor-mediated NO production and vascular relaxation in different blood vessel types. For this purpose, sphingosine kinase translocation and sphingolipid-dependent NO-production after...
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PMID: 18777003
PDF is available here.
PDF is available here.
Abstract
This study investigated the effects of thiopental on endothelium-dependent relaxation (EDR), and especially the effects on nitric oxide- and prostacyclin-independent EDR. Fresh porcine coronary artery rings (4 mm long), were consecutively tested with and without 20 microg/ml thiopental in Krebs-Hens...
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PMID: 19761683
PDF is available here.
PDF is available here.
Abstract
Even as further refinements of anti-TNF continue to emerge, new biologics targeting alternative mechanisms are progressing through clinical development programs and offer the opportunity for categorically new therapeutics in the years ahead. Several of these target regulatory cytokines occupy import...
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PMID: 19786766
PDF is available here.
PDF is available here.
Abstract
Little evidence supports the use of a specific support surface or dressing over other alternatives. Similarly, there is little evidence to support routine nutritional supplementation or adjunctive therapies compared with standard care....
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PMID: 19066385
PDF is available here.
PDF is available here.
Abstract
We have demonstrated that endothelium-derived hydrogen peroxide (H2O2) is an EDHF in animals and humans and that superoxide anions derived from endothelial nitric oxide synthases (NOSs) system are an important precursor for EDHF/H2O2 in mice. There are several intracellular sources of superoxide ani...
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PMID: 19034034
PDF is available here.
PDF is available here.
European Journal of Pharmacology (599)1-3 2008
Abstract
We hypothesized that cilostazol could improve endothelial dysfunctions in mesenteric arteries isolated from type 2 diabetic Otsuka Long-Evans Tokushima Fatty (OLETF) rats. Using cilostazol-treated (100 mg/kg/day for 4 weeks) or -untreated OLETF and control (Long Evans Tokushima Otsuka) rats, we exam...
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PMID: 18930728
PDF is available here.
PDF is available here.
Analyst (Cambridge UK) (133)11 2008
Abstract
The biological events occurring in the body are complex and challenging to decode. The expression, production, secretion and interaction of proteins, peptides and small molecules often occur in a fast manner and at low concentrations. Methods used to quantify these events must be rapid, selective, s...
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PMID: 18936823
PDF is available here.
PDF is available here.